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EC Tree
IUBMB Comments Broad specificity; reduces a number of compounds produced by Pseudomonas from aromatic hydrocarbons by ring fission.
The expected taxonomic range for this enzyme is: Pseudomonas cruciviae
Synonyms
reductase,2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate),
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reductase,2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate)
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2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+
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2,6-dioxo-6-phenylhexanoate:NADP+ DELTA2-oxidoreductase
Broad specificity; reduces a number of compounds produced by Pseudomonas from aromatic hydrocarbons by ring fission.
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate + NADPH
2,6-dioxo-6-phenylhexanoate + NADP+
2-methoxy-6-oxo-6-phenylhexa-2,3-dienoic acid methyl ester + NADPH
2-methoxy-6-oxo-6-phenylhexa-2-enoic acid methyl ester + NADP+
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enzymes I and II
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2-methoxy-6-oxo-6-phenylhexa-2,4-dienoic acid methyl ester + NADPH
2-methoxy-6-oxo-6-phenylhexa-2-enoic acid methyl ester + NADP+
ring fission product of 3-methoxycatechol + NADPH
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enzymes I and II
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ring fission products from 3-isopropylcatechol + NADPH
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enzymes I, II and III
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ring fission products from 3-methylcatechol + NADPH
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enzymes I, II and III
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ring fission products from biphenyl-2,3-diol + NADPH
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enzymes I, II and III
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ring fission products of catechol + NADPH
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enzymes I and II
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate + NADPH
2,6-dioxo-6-phenylhexanoate + NADP+
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate + NADPH
2,6-dioxo-6-phenylhexanoate + NADP+
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2-methoxy-6-oxo-6-phenylhexa-2,4-dienoic acid methyl ester + NADPH
2-methoxy-6-oxo-6-phenylhexa-2-enoic acid methyl ester + NADP+
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2-methoxy-6-oxo-6-phenylhexa-2,4-dienoic acid methyl ester + NADPH
2-methoxy-6-oxo-6-phenylhexa-2-enoic acid methyl ester + NADP+
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enzyme III
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p-chloromercuribenzoate
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0.013
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activity of reducing enzyme III in cells grown on glucose
0.049
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activity of reducing enzyme III in cells grown on biphenyl
2.5
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate reducing enzyme III
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6
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate reducing enzyme III
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brenda
S93B1, 2-hydroxy-6-oxo-phenylhexa-2,4-dienoate reducing enzymes I, II, III
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brenda
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170000
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170000
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate reducing enzyme III, gel filtration
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2-hydroxy-6-oxo-phenylhexa-2,4-dienoate reducing enzyme III
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Omori, T.; Ishigooka, H.; Minoda, Y.
Purification and some properties of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) reducing enzyme from Pseudomonas cruciviae S93B1 involved in the degradation of biphenyl
Agric. Biol. Chem.
50
1513-1518
1986
Pseudomonas cruciviae
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brenda
Omori, T.; Ishigooka, H.; Minoda, Y.
A new metabolic pathway for meta ring-fission compounds of biphenyl
Agric. Biol. Chem.
52
503-509
1988
Pseudomonas cruciviae
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brenda
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1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
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