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Information on EC 1.3.1.116 - 7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase

for references in articles please use BRENDA:EC1.3.1.116
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IUBMB Comments
Contains FAD and FMN. The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7alpha-dehydroxylation pathway. The enzyme catalyses the stereo-specific oxidation of its substrate and has no activity with the 7alpha anomer. cf. EC 1.3.1.115, 3-oxocholoyl-CoA 4-desaturase.
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The expected taxonomic range for this enzyme is: [Clostridium] scindens
Synonyms
7beta-hydroxy-3-oxo-DELTA4-cholenoic acid oxidoreductase, BaiH, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
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PATHWAY SOURCE
PATHWAYS
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