show all | hide all No of entries

Information on EC 1.3.1.115 - 3-oxocholoyl-CoA 4-desaturase

for references in articles please use BRENDA:EC1.3.1.115
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Contains flavin. The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7alpha-dehydroxylation pathway. The enzyme catalyses the stereo-specific oxidation of its substrates and has no activity with the 7beta anomers. cf. EC 1.3.1.116, 7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase.
Specify your search results
Select one or more organisms in this record:
The expected taxonomic range for this enzyme is: Clostridium scindens
Synonyms
3-oxo-DELTA4-cholenoic acid oxidoreductase, BaiCD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
show the reaction diagram
(1)
-
-
-
7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
show the reaction diagram
(2)
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.