Information on EC 1.3.1.109 - butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin)

for references in articles please use BRENDA:EC1.3.1.109
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme is a complex of a flavin-containing dehydrogenase component (Bcd) and an electron-transfer flavoprotein dimer (EtfAB). The enzyme complex, isolated from the bacteria Acidaminococcus fermentans and butanoate-producing Clostridia species, couples the exergonic reduction of (E)-but-2-enoyl-CoA to butanoyl-CoA by NADH to the endergonic reduction of ferredoxin by NADH, using electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.
Specify your search results
Select one or more organisms in this record: ?
Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
2
+
2
reduced ferredoxin [iron-sulfur] cluster
=
+
2
+
2
oxidized ferredoxin [iron-sulfur] cluster
Synonyms
BCD, Bcd/electron-transfer flavoprotein complex, Bcd/EtfAB, BcdA-EtfBC, Bct/Etf complex, bifurcating butanoyl-CoA dehydrogenase, bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex, bifurcating butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase (NAD+, ferredoxin), butanoyl-CoA dehydrogenase/Etf complex, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
butanoyl-CoA + 2 NAD+ + 2 reduced ferredoxin [iron-sulfur] cluster = (E)-but-2-enoyl-CoA + 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster
show the reaction diagram
-
-
-
-
Select items on the left to see more content.