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Information on EC 1.21.4.1 - D-proline reductase

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IUBMB Comments
The reaction is observed only in the direction of D-proline reduction. Other dithiols can function as reducing agents; the enzyme contains a pyruvoyl group and a selenocysteine residue, both essential for activity.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
a [PrdC protein with a selenide-sulfide bridge]
=
+
a [PrdC protein with thiol/selenol residues]
Synonyms
d-proline reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-aminopentanoate + a [PrdC protein with a selenide-sulfide bridge] = D-proline + a [PrdC protein with thiol/selenol residues]
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-
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