Information on EC - formaldehyde dismutase

for references in articles please use BRENDA:EC1.2.98.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
       formaldehyde dismutase
IUBMB Comments
The enzyme contains a tightly but noncovalently bound NADP(H) cofactor, as well as Zn2+ and Mg2+. Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP+ by reaction with a second formaldehyde, yielding methanol. The enzyme from the bacterium Mycobacterium sp. DSM 3803 also catalyses the reactions of EC, alcohol dehydrogenase (nicotinoprotein) and EC, methanol dehydrogenase (nicotinoprotein) . Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors [1,2].
Specify your search results
Select one or more organisms in this record: ?
Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes
aldehyde dismutase, cannizzanase, dismutase, formaldehyde, FDM, N,N9-dimethyl-4-nitrosoaniline oxidoreductase, more
2 formaldehyde + H2O = formate + methanol
show the reaction diagram
Select items on the left to see more content.