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Information on EC 1.2.5.2 - aldehyde dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.2.5.2

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IUBMB Comments

Wide specificity; acts on straight-chain aldehydes up to C10, aromatic aldehydes, glyoxylate and glyceraldehyde. The enzymes contains a PQQ cofactor and multiple hemes that deliver the electrons to the membrane quinone pool.

The enzyme appears in viruses and cellular organisms

Synonyms
adh iib, adh iig, pqq-aldh, swit_4395, formaldehyde-oxidizing enzyme, pqq-alddh, tetrahydrofurfuryl alcohol dehydrogenase, pyrroloquinoline quinone-dependent aldehyde dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an aldehyde + a quinone + H2O = a carboxylate + a quinol
show the reaction diagram
PATHWAY SOURCE
PATHWAYS