We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Information on EC 1.2.1.81 - sulfoacetaldehyde dehydrogenase (acylating) for references in articles please use BRENDA:EC1.2.1.81
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments The enzyme is involved in degradation of sulfoacetate. In this pathway the reaction is catalysed in the reverse direction. The enzyme is specific for sulfoacetaldehyde and NADP+.
The expected taxonomic range for this enzyme is: Cupriavidus necator
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SauS
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-sulfoacetaldehyde + CoA + NADP+ = sulfoacetyl-CoA + NADPH + H+
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating)
The enzyme is involved in degradation of sulfoacetate. In this pathway the reaction is catalysed in the reverse direction. The enzyme is specific for sulfoacetaldehyde and NADP+.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-sulfoacetaldehyde + CoA + NADP+
sulfoacetyl-CoA + NADPH + H+
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
2-sulfoacetaldehyde + CoA + NADP+
sulfoacetyl-CoA + NADPH + H+
specific for NADP+, no activity with NAD+. The enzyme is specific for sulfoacetaldehyde. No activity with: acetaldehyde, phosphonoacetaldehyde, glycolaldehyde, formaldehyde, propionaldehyde, succinic semialdehyde, glyoxylate, betaine aldehyde, glyceraldehyde, and 2-oxobutanoic acid
-
-
r
2-sulfoacetaldehyde + CoA + NADP+
sulfoacetyl-CoA + NADPH + H+
specific for NADP+, no activity with NAD+. The enzyme is specific for sulfoacetaldehyde. No activity with: acetaldehyde, phosphonoacetaldehyde, glycolaldehyde, formaldehyde, propionaldehyde, succinic semialdehyde, glyoxylate, betaine aldehyde, glyceraldehyde, and 2-oxobutanoic acid
-
-
r
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
the enzyme is involved in degradation of sulfoacetate
-
-
?
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
the enzyme is involved in degradation of sulfoacetate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
Q0K845
the enzyme is involved in degradation of sulfoacetate
-
-
?
sulfoacetyl-CoA + NADPH + H+
2-sulfoacetaldehyde + CoA + NADP+
Q0K845
the enzyme is involved in degradation of sulfoacetate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NADP+
specific for NADP+, no activity with NAD+
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
-
no inhibition: acetaldehyde, phosphonoacetaldehyde, glycolaldehyde, formaldehyde, propionaldehyde, succinic semialdehyde, glyoxylate, betaine aldehyde, glyceraldehyde, and 2-oxobutanoic acid
-
additional information
no inhibition: acetaldehyde, phosphonoacetaldehyde, glycolaldehyde, formaldehyde, propionaldehyde, succinic semialdehyde, glyoxylate, betaine aldehyde, glyceraldehyde, and 2-oxobutanoic acid
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.33
2-sulfoacetaldehyde
pH 9.0, temperature not specified in the publication
0.102
CoA
pH 9.0, temperature not specified in the publication
0.064
NADP+
pH 9.0, temperature not specified in the publication
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
UniProt
brenda
-
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
inducible activity. Extracts of acetate-, taurine-, or isethionate-grown cells show no activity, extracts of sulfoacetate-grown cells catalyze the reaction
brenda
-
inducible activity. Extracts of acetate-, taurine-, or isethionate-grown cells show no activity, extracts of sulfoacetate-grown cells catalyze the reaction
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
malfunction
deletion mutant does not grow on sulfoacetate
malfunction
-
deletion mutant does not grow on sulfoacetate
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SAUS_CUPNH
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
493
0
51647
Swiss-Prot
A0A1X7BVV5_9RHOB
469
0
49259
TrEMBL
A0A2Z2NY54_9GAMM
478
0
50786
TrEMBL
A0A375EFT5_9BURK
481
0
50339
TrEMBL
A0A375GUX5_9BURK
481
0
50658
TrEMBL
A0A0N7MAQ0_9RHOB
473
0
49900
TrEMBL
A0A177HC31_9RHOB
469
0
50173
TrEMBL
A0A0P1IKW7_9RHOB
467
0
49294
TrEMBL
A0A0N7LR76_9RHOB
473
0
49338
TrEMBL
A0A1R4H3L2_9GAMM
470
0
50809
TrEMBL
A0A1X6ZYN3_9RHOB
467
0
49612
TrEMBL
A0A3N6HSR5_9ACTN
472
0
49621
TrEMBL
A0A011PYP7_9PROT
465
0
49160
TrEMBL
A0A1X6ZQQ9_9RHOB
467
0
50512
TrEMBL
A0A1J5R6R4_9ZZZZ
480
0
51258
TrEMBL
A0A1J5R6T9_9ZZZZ
475
0
50894
TrEMBL
A0A375BML8_9BURK
481
0
50459
TrEMBL
A0A1K0IP04_CUPNE
493
0
51471
TrEMBL
A0A238JLA6_9RHOB
471
0
49705
TrEMBL
A0A0P1EXY1_9RHOB
467
0
49752
TrEMBL
A0A2S6TG73_9PROT
442
0
46414
TrEMBL
A0A0P1G9L7_9RHOB
467
0
49171
TrEMBL
A0A1X6YZA5_9RHOB
469
0
49640
TrEMBL
A0A2H6IWE8_9BACT
477
0
50596
TrEMBL
A0A0M6YQK1_9RHOB
469
0
50948
TrEMBL
A0A2S6UQD3_9PROT
473
0
51803
TrEMBL
A0A1V5EAD0_9DELT
463
0
50753
TrEMBL
A0A1Y5SHM6_9RHOB
466
0
49527
TrEMBL
A0A1Y5SQ71_9RHOB
469
0
49220
TrEMBL
M1ZFW5_9FIRM
[Clostridium] ultunense Esp
462
0
51007
TrEMBL
M1ZB15_9FIRM
[Clostridium] ultunense Esp
465
0
50901
TrEMBL
A0A375IC76_9BURK
481
0
50688
TrEMBL
A0A2S6U954_9PROT
474
0
50182
TrEMBL
A0A0D6JJ56_9RHIZ
483
0
52399
TrEMBL
A0A1M4PL84_9FIRM
[Clostridium] ultunense Esp
428
0
47074
TrEMBL
A0A0U1NNA7_9RHOB
461
0
48727
TrEMBL
A0A375IZ70_9BURK
481
0
50585
TrEMBL
A0A1N7RZW6_9BURK
481
0
50878
TrEMBL
A0A238KKG2_9RHOB
90
0
9784
TrEMBL
V5C668_9GAMM
471
0
50778
TrEMBL
A0A0P1IMJ9_9RHOB
283
0
30784
TrEMBL
A0A2R8C970_9RHOB
469
0
49257
TrEMBL
A0A3N6GUM9_9ACTN
474
0
49919
TrEMBL
A0A1X6ZIW8_9RHOB
473
0
49498
TrEMBL
A0A1M4PL46_9FIRM
[Clostridium] ultunense Esp
372
0
43052
TrEMBL
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
52000
2 * 52000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dimer
2 * 52000, SDS-PAGE
dimer
-
2 * 52000, SDS-PAGE
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
4°C or -18°C, 1 week, 30% loss of activity
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
inducible activity. Extracts of acetate-, taurine-, or isethionate-grown cells show no activity, extracts of sulfoacetate-grown cells catalyze the reaction
inducible activity. Extracts of acetate-, taurine-, or isethionate-grown cells show no activity, extracts of sulfoacetate-grown cells catalyze the reaction
inducible activity. Extracts of acetate-, taurine-, or isethionate-grown cells show no activity, extracts of sulfoacetate-grown cells catalyze the reaction
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Weinitschke, S.; Hollemeyer, K.; Kusian, B.; Bowien, B.; Smits, T.H.; Cook, A.M.
Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16
J. Biol. Chem.
285
35249-35254
2010
Cupriavidus necator, Cupriavidus necator (Q0K845), Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1 (Q0K845)
brenda
Select items on the left to see more content.
html completed
HOME
login
history
all enzymes
BRENDA home
History
1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating)
more
top
Information
