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Disease on EC 1.2.1.59 - glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
6-phosphofructokinase deficiency
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Acidosis
Binding of cytosolic proteins to myofibrils in ischemic rat hearts.
Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones.
Effects of treatment with pyruvate and tromethamine in experimental myocardial ischemia.
Acidosis, Lactic
Regulation of glyceraldehyde 3-phosphate dehydrogenase expression by metformin in HepG2 cells.
Acquired Immunodeficiency Syndrome
Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block.
[Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference]
ACTH-Secreting Pituitary Adenoma
Decreased expression of corticotropin-releasing factor-binding protein mRNA in ACTH-secreting pituitary adenomas.
Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion.
Acute Kidney Injury
The modifier protein of glyceraldehyde-3-phosphate dehydrogenase reduces free radical-mediated renal damage in a rat model of acute kidney injury.
Acute Lung Injury
A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
Adenocarcinoma
Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma.
CD133 mRNA expression and microsatellite instability in colorectal carcinoma.
Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases.
Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma.
Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin.
Increased expression of glycolysis-associated genes in oncogene-transformed and growth-accelerated states.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma.
Sequential histochemical and morphometric studies on preneoplastic and neoplastic lesions induced in rat colon by 1,2-dimethylhydrazine.
Simultaneous down-regulation of tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer.
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism.
UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells.
Adenocarcinoma of Lung
Aberrant Methylation and Differential Expression of SLC2A1, TNS4, GAPDH, ATP8A2, and CASZ1 Are Associated with the Prognosis of Lung Adenocarcinoma.
Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro.
Guanylate binding protein 1 (GBP-1) promotes cell motility and invasiveness of lung adenocarcinoma.
Inferring genome-wide functional modulatory network: a case study on NF-?B/RelA transcription factor.
LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis.
Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme.
The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis.
The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
Adenolymphoma
Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors.
Adenoma
Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas.
Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction.
Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine.
Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors.
Selection and validation of reliable reference genes for RT-qPCR analysis in a large cohort of pituitary adenomas.
Selection of an internal control gene for quantitation of mRNA in colonic tissues.
Adenoma, Bile Duct
Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet.
Adenoma, Liver Cell
Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet.
Adenoma, Oxyphilic
Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors.
Adenomatous Polyposis Coli
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Albinism
Correlations between photosynthetic enzymes, CO2-fixation and plastid structure in an albino mutant of Zea mays L.
Alkalosis
Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones.
alpha-Thalassemia
A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe.
Alzheimer Disease
A Proteomic Approach for the Involvement of the GAPDH in Alzheimer Disease in the Blood of Moroccan FAD Cases.
Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
AMPK activation does not enhance autophagy in neurons in contrast to MTORC1 inhibition: different impact on ?-amyloid clearance.
Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease.
An investigation of the correlation between the S-glutathionylated GAPDH levels in blood and Alzheimer's disease progression.
Assessment of GAPDH expression by quantitative real time PCR in blood of Moroccan AD cases.
Association and heterogeneity at the GAPDH locus in Alzheimer's disease.
Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders.
Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease.
Disclosure of a pro-apoptotic glyceraldehyde-3-phosphate dehydrogenase promoter: anti-dementia drugs depress its activation in apoptosis.
Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.
Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-? Aggregation and Cytotoxicity.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease.
Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-? Amyloidogenesis in Alzheimer Disease.
Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.
Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain.
Glyceraldehyde-3-phosphate dehydrogenase tetramer dissociation and amyloid fibril formation induced by negatively charged membranes.
Isolation of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) cDNA from the distal half of mouse chromosome 16: further indication of a link between Alzheimer's disease and glycolysis.
MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Non-native glyceraldehyde-3-phosphate dehydrogenase can be an intrinsic component of amyloid structures.
Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration.
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation.
Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein.
Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance.
Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts.
Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts.
Amyotrophic Lateral Sclerosis
Determination of protein and RNA expression levels of common housekeeping genes in a mouse model of neurodegeneration.
Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis.
GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Anaphylaxis
Glyceraldehyde-3-phosphate dehydrogenase as a major allergen in rambutan-induced anaphylaxis.
Anemia
Increased membrane activity of glyceraldehyde 3-phosphate dehydrogenase in erythrocytes of patients with homozygous sickle cell anaemia.
Anemia, Sickle Cell
Increased membrane activity of glyceraldehyde 3-phosphate dehydrogenase in erythrocytes of patients with homozygous sickle cell anaemia.
Anthrax
Surface localized and extracellular Glyceraldehyde-3-phosphate dehydrogenase of Bacillus anthracis is a plasminogen binding protein.
Arthritis
Gapdh Gene Expression Is Modulated by Inflammatory Arthritis and Is not Suitable for qPCR Normalization.
Oxidation of articular cartilage glyceraldehyde-3-phosphate dehydrogenase (G3PDH) occurs in vivo during carrageenin-induced arthritis.
Arthritis, Rheumatoid
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.
Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204.
Asthenozoospermia
Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa.
Asthma
beta-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels.
Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge.
Novel insights in mammalian catalase heme maturation: Effect of NO and thioredoxin-1.
Reference genes for real-time qPCR in leukocytes from asthmatic patients before and after anti-asthma treatment.
Astrocytoma
ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.
E3 ubiquitin ligase siah?1 nuclear accumulation is critical for homocysteine?induced impairment of C6 astroglioma cells.
GAPDH is not regulated in human glioblastoma under hypoxic conditions.
Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma.
Selection of reference genes for gene expression studies in astrocytomas.
Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR.
Ataxia Telangiectasia
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.
Atherosclerosis
Expression Profile and Subcellular Localization of GAPDH in the Smooth Muscle Cells of Human Atherosclerotic Plaque: An Immunohistochemical and Ultrastructural Study with Biological Therapeutic Perspectives.
Atrial Fibrillation
Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart.
Autoimmune Diseases
Identification of Glyceraldehyde-3-Phosphate and Alcohol Dehydrogenases as Autoantigens in Doberman Hepatitis.
Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders.
Natural product 1,2,3,4,6-penta-O-galloyl-?-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.
Avitaminosis
Vitamin B6 deficiency causes activation of RNA polymerase and general enhancement of gene expression in rat liver.
Azoospermia
Quantification of cyclin A1 and glyceraldehyde-3-phosphate dehydrogenase expression in testicular biopsies of infertile patients by fluorescence real-time RT-PCR.
Bacterial Infections
Bacterial endotoxin lipopolysaccharide induces up-regulation of glyceraldehyde-3-phosphate dehydrogenase in rat liver and lungs.
Determination of internal controls for quantitative real time RT-PCR analysis of the effect of Edwardsiella tarda infection on gene expression in turbot (Scophthalmus maximus).
Evaluation of candidate reference genes for quantitative expression studies in Asian seabass (Lates calcarifer) during ontogenesis and in tissues of healthy and infected fishes.
Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment.
beta-Thalassemia
Analysis of Erythrocyte and Platelet Membrane Proteins in Various Forms of beta-Thalassemia.
Blast Crisis
Gene Expression upon Proliferation and Differentiation of Hematopoietic Cells with Ph Chromosome ex vivo.
Bluetongue
Simultaneous detection of bluetongue virus RNA, internal control GAPDH mRNA, and external control synthetic RNA by multiplex real-time PCR.
Brain Infarction
Structural change and degradation of cytoskeleton due to the acrolein conjugation with vimentin and actin during brain infarction.
Brain Injuries
Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling
Brain Injuries, Traumatic
Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury.
Hydrocortisone 21-hemisuccinate did not prevent exogenous GAPDH-induced apoptosis in human neuroblastoma cells.
Inhibition of EphA/Ephrin-A signaling using genetic and pharmacologic approaches improves recovery following traumatic brain injury in mice.
Brain Ischemia
Disruption of the GluR2/GAPDH complex protects against ischemia-induced neuronal damage.
Brain Neoplasms
Expression of ?-adrenergic receptors in pediatric malignant brain tumors.
[Enzymes in cerebrospinal fluid (HK, TIM, GAPDH, PGK, enolase, PK, LDH, GPT, ChE) in normal samples, in brain neoplasms and other neurologic diseases]
Breast Neoplasms
A microfluidic approach to parallelized transcriptional profiling of single cells.
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Alteration of GLIS3 gene expression pattern in patients with breast cancer.
Autophagy-related prognostic signature for breast cancer.
Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats.
Comparative expression of fibroblast growth factor mRNAs in benign and malignant breast disease.
Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods.
Cytosolic and Transmembrane Protein Extraction Methods of Breast and Ovarian Cancer Cells: A Comparative Study.
Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes.
Efficient Dual siRNA and Drug Delivery Using Engineered Lipoproteoplexes.
Enhanced gene expression in breast cancer cells in vitro and tumors in vivo.
Enzymes of carbohydrate metabolism in human breast carcinoma: relationship with serum hormones.
Estrogen receptor alpha (ER alpha) mRNA copy numbers in immunohistochemically ER alpha-positive-, and negative breast cancer tissues.
Fatty acid-bearing albumin but not fatty acid-depleted albumin induces HIF-1 activation in human renal proximal tubular epithelial cell line HK-2.
Gene expression and pathologic response to neoadjuvant chemotherapy in breast cancer.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component.
Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3.
Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer.
Glycolaldehyde induces apoptosis in a human breast cancer cell line.
Heterogeneous Cell Types in Single-cell-derived Clones of MCF7 and MDA-MB-231 Cells.
Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues.
Identification of potential prognostic biomarkers for node-negative breast tumours by proteomic analysis: a multicentric 2004 national PHRC study.
Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy.
Measurement of mRNA levels in tumor xenografts with quantitative autoradiography and in situ hybridization.
Nitroxyl inhibits breast tumor growth and angiogenesis.
Novel insight into the role of GAPDH playing in tumor.
Overexpression of Stat3 increases circulating cfDNA in breast cancer.
Parallel assessment of circulatory cell-free DNA by PCR and nucleosomes by ELISA in breast tumors.
Profiling protein expression in circulating tumour cells using microfluidic western blotting.
Proteomics using mammospheres as a model system to identify proteins deregulated in breast cancer stem cells.
Quantitative detection of circulating epithelial cells by Q-RT-PCR.
RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.
Shortening of apparent transverse relaxation time of inorganic phosphate as a breast cancer biomarker.
Single-cell multiple gene expression analysis based on single-molecule-detection microarray assay for multi-DNA determination.
Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
Tissue-Specific Warburg Effect in Breast Cancer and Cancer-Associated Adipose Tissue-Relationship between AMPK and Glycolysis.
Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells.
[Breast cancer diagnostics based on extracellular DNA and RNA circulating in blood]
Brucellosis
Brucella abortus L7/L12 recombinant protein induces strong Th1 response in acute brucellosis patients.
Bulbo-Spinal Atrophy, X-Linked
Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Burkitt Lymphoma
The mode of actions of glyceraldehyde-3-phosphate dehydrogenase identified as an immunoglobulin production stimulating factor.
ca2+/calmodulin-dependent protein kinase deficiency
Hypomorphic CAMKK2 in EA.hy926 endothelial cells causes abnormal transferrin trafficking, iron homeostasis and glucose metabolism.
Candidiasis
Clinical strains of Candida albicans express the surface antigen glyceraldehyde 3-phosphate dehydrogenase in vitro and in infected tissues.
Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model.
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
The cell wall-associated glyceraldehyde-3-phosphate dehydrogenase of Candida albicans is also a fibronectin and laminin binding protein.
Candidiasis, Invasive
Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model.
Carcinogenesis
Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target.
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.
GAPDH: A common enzyme with uncommon functions.
Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase.
Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma.
Increased expression of glycolysis-associated genes in oncogene-transformed and growth-accelerated states.
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review.
Moonlighting glyceraldehyde-3-phosphate dehydrogenase: posttranslational modification, protein and nucleic acid interactions in normal cells and in human pathology.
Novel protein and immune response markers of human serous tubal intraepithelial carcinoma of the ovary.
Novel roles for GAPDH in cell death and carcinogenesis.
Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases.
Proteomics using mammospheres as a model system to identify proteins deregulated in breast cancer stem cells.
Selection of reference genes for real-time PCR in human hepatocellular carcinoma tissues.
Similarity between glyceraldehyde-3-phosphate dehydrogenase and a 37,000-dalton protein which is abundantly expressed in human lung cancers.
Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis.
The bioenergetic signature of cancer: a marker of tumor progression.
Transcriptional regulation of glyceraldehyde-3-phosphate dehydrogenase by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.
Carcinoma
Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors.
Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells.
Alteration of glyceraldehyde-3-phosphate dehydrogenase activity and messenger RNA content by androgen in human prostate carcinoma cells.
Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines.
Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells.
Chromatin-associated proteins HMGB1/2 and PDIA3 trigger cellular response to chemotherapy-induced DNA damage.
Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma.
Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines.
Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas.
Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Elevated GAPDH Expression is Associated with the Proliferation and Invasion of Lung and Esophageal Squamous Cell Carcinomas.
Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas.
Evaluation of digital real-time PCR assay as a molecular diagnostic tool for single-cell analysis.
Evidence for the presence of a critical histidine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cells.
Exploring polyps to colon carcinoma voyage: can blocking the crossroad halt the sequence?
Expression of human prostatic acid phosphatase and prostate specific antigen genes in neoplastic and benign tissues.
Gene expression profiles in thyroid carcinomas.
Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma.
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines.
Glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites carcinoma cells its possible role in the high glycolysis of malignant cells.
Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis.
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine.
Identification of a critical lysine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cell. Comparison with the rabbit muscle enzyme.
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma.
Identification of reference genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq.
Identification of suitable reference genes for investigating gene expression in human gallbladder carcinoma using reverse transcription quantitative polymerase chain reaction.
Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers.
Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells.
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells.
Oxidative stress in HPV-driven viral carcinogenesis: redox proteomics analysis of HPV-16 dysplastic and neoplastic tissues.
Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors.
Reference gene selection for head and neck squamous cell carcinoma gene expression studies.
Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide.
RT-PCR amplification of RNA extracted from formalin-fixed, paraffin-embedded oral cancer sections: analysis of p53 pathway.
Sequential histochemical and morphometric studies on preneoplastic and neoplastic lesions induced in rat colon by 1,2-dimethylhydrazine.
Specific inhibition of glyceraldehyde-3-phosphate dehydrogenase by koningic acid (heptelidic acid).
The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions.
The bioenergetic signature of cancer: a marker of tumor progression.
[Proteomic identification and comparison of differentiation-related proteins in gastric carcinoma cell lines]
[Quantitative analysis of epidermal growth factor receptor mRNA in laryngeal carcinoma by reverse transcription-real time polymerase chain reaction with TagMan probe]
Carcinoma, Basal Cell
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Carcinoma, Ehrlich Tumor
Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase.
Properties of the glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites tumor cells.
Carcinoma, Hepatocellular
Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro.
Anti-hepatocarcinogenic and Anti-oxidant Effects of Mangrove Plant Scyphiphora hydrophyllacea.
Cationic lipid nanodisks as an siRNA delivery vehicle.
Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma.
Comparison of glyceraldehyde-3-phosphate dehydrogenase and 28s-ribosomal RNA gene expression in human hepatocellular carcinoma.
Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway.
Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-?.
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
Glyceraldehyde-3-phosphate dehydrogenase mRNA expression in hepatocellular carcinoma.
Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase.
Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma.
High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis.
Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.
Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis.
Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.
Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism.
Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior.
p53 is not necessary for nuclear translocation of GAPDH during NO-induced apoptosis.
Targets of 3-Bromopyruvate, a New, Energy Depleting, Anticancer Agent.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.
Carcinoma, Non-Small-Cell Lung
Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells.
Choice of endogenous control for gene expression in nonsmall cell lung cancer.
Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPK? signaling in STK11 mutant lung cancer.
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy.
Carcinoma, Ovarian Epithelial
Association of metastin/a G-protein-coupled receptor signaling and Down syndrome critical region 1 in epithelial ovarian cancer.
Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer.
Carcinoma, Papillary
Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction.
Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors.
Carcinoma, Renal Cell
Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma.
Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.
Carcinoma, Squamous Cell
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Elevated GAPDH Expression is Associated with the Proliferation and Invasion of Lung and Esophageal Squamous Cell Carcinomas.
Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas.
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma.
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Reference gene selection for head and neck squamous cell carcinoma gene expression studies.
Carcinoma, Transitional Cell
Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas.
Cardiomegaly
Identification of Potentially Relevant Genes for Excessive Exercise-Induced Pathological Cardiac Hypertrophy in Zebrafish.
Cardiomyopathies
Differential expression of tissue inhibitors of metalloproteinases in the failing human heart.
Cardiomyopathy, Alcoholic
From the Cover: Alcohol Inhibition of the Enzymatic Activity of Glyceraldehyde 3-Phosphate Dehydrogenase Impairs Cardiac Glucose Utilization, Contributing to Alcoholic Cardiomyopathy.
Cardiomyopathy, Dilated
Differential expression of tissue inhibitors of metalloproteinases in the failing human heart.
Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium.
Cardiotoxicity
Toxicity Evaluation and Biomarker Selection with Validated Reference Gene in Embryonic Zebrafish Exposed to Mitoxantrone.
Cardiovascular Diseases
Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1.
Cataract
"Moonlighting" GAPDH Protein Localizes with AMPA Receptor GluA2 and L1 Axonal Cell Adhesion Molecule at Fiber Cell Borders in the Lens.
Changes in calpain II mRNA in young rat lens during maturation and cataract formation.
Proteomic analysis of human age-related nuclear cataracts and normal lens nuclei.
Revival of inactive glyceraldehyde 3-phosphate dehydrogenase in human cataract lenses by reduction.
Thioredoxin, thioredoxin reductase, and alpha-crystallin revive inactivated glyceraldehyde 3-phosphate dehydrogenase in human aged and cataract lens extracts.
Central Nervous System Protozoal Infections
Expression, purification, enzymatic characterization and crystallization of glyceraldehyde-3-phosphate dehydrogenase from Naegleria gruberi, the first one from phylum Percolozoa.
Chagas Disease
3D QSAR studies on binding affinities of coumarin natural products for glycosomal GAPDH of Trypanosoma cruzi.
Development and characterization of an immobilized enzyme reactor (IMER) based on human glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies.
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors.
Expression, purification and kinetic characterization of His-tagged glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi.
Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors.
Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design.
Cholesteatoma
Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients.
Chordoma
Validation of reference genes in human chordoma.
Choriocarcinoma
Nuclear beta-catenin and Ki-67 expression in choriocarcinoma and its pre-malignant form.
Transglutaminase 2-dependent deamidation of glyceraldehyde-3-phosphate dehydrogenase promotes trophoblastic cell fusion.
Coinfection
Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig-to-baboon renal xenotransplantation in vivo.
Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda.
Molecular characterization of native Australian trypanosomes in quokka (Setonix brachyurus) populations from Western Australia.
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza.
Colitis, Ulcerative
Enhanced intramucosal cytotoxic lymphocyte gene expression in ulcerative colitis.
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
Colonic Neoplasms
Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Celastrol inhibits colorectal cancer through TGF-?1/Smad signaling.
Gene expression profile analysis of colon cancer grade II into grade III transition by using system biology.
Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma.
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression.
Gossypol decreased cell viability and down-regulated the expression of a number of genes in human colon cancer cells.
Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.
Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma.
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.
Selection of an internal control gene for quantitation of mRNA in colonic tissues.
Serum availability affects expression of common house-keeping genes in colon adenocarcinoma cell lines: implications for quantitative real-time PCR studies.
Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use.
Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.
Colorectal Neoplasms
Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells.
Apolipoprotein M increases the expression of vitamin D receptor mRNA in colorectal cancer cells detected with duplex fluorescence reverse transcription-quantitative polymerase chain reaction.
Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate.
Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma.
Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma.
Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer.
Increased translocator protein (TSPO) mRNA levels in colon but not in rectum carcinoma.
Is GAPDH a relevant housekeeping gene for normalisation in colorectal cancer experiments?
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Novel insight into the role of GAPDH playing in tumor.
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.
Ropivacaine inhibits the proliferation and migration of colorectal cancer cells through ITGB1.
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Vitamin C Targets GAPDH to Kill KRAS- and BRAF-Mutant Cancer Cells.
Vitamin C, a Multi-Tasking Molecule, Finds a Molecular Target in Killing Cancer Cells.
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
[Expression of osteopontin mRNA and its protein in colorectal cancer and liver metastatic tissues]
Congenital Hypothyroidism
Glyceraldehyde-3-phosphate dehydrogenase activity in developing brain during experimental cretinism.
Connective Tissue Diseases
Glyceraldehyde 3-phosphate dehydrogenase is a novel autoantigen leading autoimmune responses to proliferating cell nuclear antigen multiprotein complexes in lupus patients.
Contracture
Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid.
Metabolic myopathy produced by dinitrofluorobenzene inhibition of creatine phosphokinase.
COVID-19
Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases.
Interferon-stimulated gene products as regulators of central carbon metabolism.
Crohn Disease
Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies.
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
Cryptosporidiosis
Cryptosporidiosis Modulates the Gut Microbiome and Metabolism in a Murine Infection Model.
Cystadenoma
[Study of the genes correlated with cyst calcification in patients with cystic echinococcosis].
Cystic Fibrosis
Decreased basal chloride secretion and altered cystic fibrosis transmembrane conductance regulatory protein, Villin, GLUT5 protein expression in jejunum from leptin-deficient mice.
Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation.
Cysts
Differential dissolved protein expression throughout the life cycle of Giardia lamblia.
Effect of mebendazole and praziquantel on glucosephosphate isomerase and glyceraldehydephosphate dehydrogenase in Echinococcus granulosus cyst wall harbored in mice.
Dehydration
Dehydration and ABA increase mRNA levels and enzyme activity of cytosolic GAPDH in the resurrection plant Craterostigma plantagineum.
Mind the GAP: Purification and characterization of urea resistant GAPDH during extreme dehydration.
Validation of novel reference genes for reverse transcription quantitative real-time PCR in drought-stressed sugarcane.
[Activity of NADP-dependent glyceraldehyde-phosphate dehydrogenase and phosphoenolpyruvate carboxylase in wheat leaves under water stress]
Dengue
Dengue virus nonstructural 3 protein interacts directly with human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and reduces its glycolytic activity.
Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity.
Endogenous gene selection for relative quantification PCR and IL6 transcript levels in the PBMC's of severe and non-severe dengue cases.
HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons.
Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors.
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells.
Recombinant dengue virus-like particles from Pichia pastoris: efficient production and immunological properties.
Dermatitis, Atopic
Reference genes for canine skin when using quantitative real-time PCR.
Relative importance of IL-4 and IL-13 in lesional skin of atopic dermatitis.
Dermatitis, Contact
Quantitative polymerase chain reaction using an external control mRNA for determination of gene expression in a heterogeneous cell population.
Diabetes Complications
Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance.
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes.
Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.
Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos.
Methylglyoxal can modify GAPDH activity and structure.
Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.
Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.
The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity.
[Molecular pathophysiology of late complications diabetes mellitus--hyperglycemia-induced changes]
Diabetes Mellitus
Fudenine, a C-terminal truncated rat homologue of mouse prominin, is blood glucose-regulated and can up-regulate the expression of GAPDH.
Oxidation of glyceraldehyde-3-phosphate dehydrogenase decreases sperm motility in diabetes mellitus.
The Shepherds' Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds.
Diabetes Mellitus, Type 1
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes.
Diabetes Mellitus, Type 2
Assessment of cell-free DNA with microvascular complication of type II diabetes mellitus, using PCR and ELISA.
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes.
Metabolism of [1,3-(13)C]glycerol-1,2,3-tris(methylsuccinate) and glycerol-1,2,3-tris(methyl[2,3-(13)C]succinate) in hepatocytes from Goto-Kakizaki rats.
Poly(ADP-ribosylated) proteins in mononuclear cells from patients with type 2 diabetes identified by proteomic studies.
Succination of proteins in diabetes.
[Contribution to the study of glyceraldehyde-3-phosphate dehydrogenase in patients with type 2 diabetes].
Diabetic Angiopathies
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction.
Diabetic Nephropathies
Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.
Diabetic Retinopathy
Assessment of cell-free DNA with microvascular complication of type II diabetes mellitus, using PCR and ELISA.
Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy.
High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules.
Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells.
Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.
Dirofilariasis
Glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis participate in heartworm disease endarteritis via plasminogen/plasmin system.
Distemper
Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions.
Down Syndrome
Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome.
Isolation of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) cDNA from the distal half of mouse chromosome 16: further indication of a link between Alzheimer's disease and glycolysis.
Sensitivity of DCSR3/GAPDH Ratio Using Quantitative Real-Time PCR in the Rapid Prenatal Diagnosis for Down Syndrome.
[Application of real-time fluorescence quantitative polymerase chain reaction techniques for prenatal diagnosis of Down syndrome]
[Rapid diagnosis of Down's syndrome by multiplex real-time fluorescence relative quantitative PCR]
Dupuytren Contracture
Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain.
Dwarfism
Plastidial glyceraldehyde-3-phosphate dehydrogenase deficiency leads to altered root development and affects the sugar and amino Acid balance in Arabidopsis.
Dysentery, Bacillary
Characterization and structure of glyceraldehyde-3-phosphate dehydrogenase type 1 from Escherichia coli.
Encephalitis, Japanese
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein.
Encephalitis, Tick-Borne
Cloning and Expression of Recombinant Tick-Borne Encephalitis Virus-like Particles in Pichia pastoris.
Encephalomyelitis
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.
Encephalomyelitis, Autoimmune, Experimental
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.
Endarteritis
Glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis participate in heartworm disease endarteritis via plasminogen/plasmin system.
Endocarditis
pH-regulated secretion of a glyceraldehyde-3-phosphate dehydrogenase from Streptococcus gordonii FSS2: purification, characterization, and cloning of the gene encoding this enzyme.
Epilepsy
Disruption of the GluA2/GAPDH complex using TAT-GluA2NT1-3-2 peptide protects against AMPAR-mediated excitotoxicity after epilepsy.
Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease.
Quantitative characterization of regional differences in the GABAA-receptor alpha1-subunit mRNA expression in the rat brain.
[Dual role for the glycolytic enzyme GAPDH in GABAergic neurotransmission and in human epilepsy]
Epilepsy, Absence
Elevated sterol regulatory elementary binding protein 1 and GluA2 levels in the hippocampal nuclear fraction of Genetic Absence Epilepsy Rats from Strasbourg.
Esophageal Neoplasms
Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with Autophagy.
Esophageal Squamous Cell Carcinoma
Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma.
Eye Infections
Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding.
Fallopian Tube Neoplasms
The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
Fascioliasis
Identification and characterization of glyceraldehyde 3-phosphate dehydrogenase from Fasciola gigantica.
Fatty Liver
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance.
Rat strain differences in susceptibility to alcohol-induced chronic liver injury and hepatic insulin resistance.
Fetal Diseases
Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos.
Fetal Growth Retardation
GAPDH, 18S rRNA and YWHAZ are suitable endogenous reference genes for relative gene expression studies in placental tissues from human idiopathic fetal growth restriction.
Fibroma
Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain.
Fibrosarcoma
The characterization of exosomes from fibrosarcoma cell and the useful usage of Dynamic Light Scattering (DLS) for their evaluation.
Filariasis
DNA vaccine encoding the moonlighting protein Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH) leads to partial protection in a mouse model of human filariasis.
Foot Rot
Reference gene selection for quantitative PCR studies in sheep neutrophils.
Friedreich Ataxia
Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders.
Ganglioneuroblastoma
Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues.
Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma.
Ganglioneuroma
Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma.
Gastric Fistula
Expression of immediate early genes in rat gastric myenteric neurones: a physiological response to feeding.
Gastritis
Comparative study of gastric cancer and chronic gastritis via network analysis.
Gastroschisis
Enterocytic gene expression is altered in experimental gastroschisis.
Glaucoma
Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.
Glioblastoma
A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.
Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro.
ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.
Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress.
Expression of insulin-like growth factor binding protein-2 (IGFBP-2) gene in negative and positive human cytomegalovirus glioblastoma multiforme tissues.
GAPDH is not regulated in human glioblastoma under hypoxic conditions.
High-selectivity cytology via lab-on-a-disc western blotting of individual cells.
Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells.
Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH.
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2.
Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells.
Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR.
Glioma
ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.
Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells.
HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell.
Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH.
Hydrogen Peroxide-Induced Oxidative Stress Activates Proteasomal Trypsin-Like Activity in Human U373 Glioma Cells.
MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2.
Novel insight into the role of GAPDH playing in tumor.
On the Relevance of Glycolysis Process on Brain Gliomas.
Quantitative reverse transcription-PCR measurement of tissue factor mRNA in glioma.
Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR.
Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation.
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Glomerulonephritis
Bacterial infection-related glomerulonephritis in adults.
CLCN5 5'UTR isoforms in human kidneys: differential expression analysis between controls and patients with glomerulonephritis.
Glyceraldehyde-3-phosphate dehydrogenase of Mycoplasma pneumoniae induces infection-related glomerulonephritis?.
Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy.
Glomerulonephritis, IGA
Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy.
Glomerulonephritis, Membranous
Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy.
Th2 cytokines increase and stimulate B cells to produce IgG4 in idiopathic membranous nephropathy.
Glomerulosclerosis, Focal Segmental
Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy.
glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency
A simple screening procedure for glucose phosphate isomerase, phosphofructokinase, aldolase and glyceraldehyde-3-phosphate dehydrogenase deficiencies.
Glyceraldehyde-3-phosphate dehydrogenase is required for efficient repair of cytotoxic DNA lesions in Escherichia coli.
Study of a kindred with hereditary spherocytosis and glyceraldehyde-3-phosphate dehydrogenase deficiency.
glycogen phosphorylase deficiency
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Glycogen Storage Disease Type V
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Glycosuria
Thyroid hormone treatment decreases hepatic glucose production and renal reabsorption of glucose in alloxan-induced diabetic Wistar rats.
Goiter
Validation of reference genes for normalization gene expression in reverse transcription quantitative PCR in human normal thyroid and goiter tissue.
Goiter, Nodular
Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker.
Granuloma
Effects of regulatory T cells on glyceraldehyde-3-phosphate dehydrogenase vaccine efficacy against Schistosoma japonicum.
Granulomatous Disease, Chronic
S-thiolation of glyceraldehyde-3-phosphate dehydrogenase induced by the phagocytosis-associated respiratory burst in blood monocytes.
Hearing Loss, Noise-Induced
Associations of Genetic Variation in Glyceraldehyde 3-Phosphate Dehydrogenase Gene with Noise-Induced Hearing Loss in a Chinese Population: A Case-Control Study.
Heart Arrest
Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model.
Heart Diseases
GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury.
Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.
Heart Failure
Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure.
Expression of proinflammatory cytokines in the failing human heart: comparison of recent-onset and end-stage congestive heart failure.
Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.
Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart.
Proteomic analysis of left ventricular remodeling in an experimental model of heart failure.
Reduced activity of enzymes coupling ATP-generating with ATP-consuming processes in the failing myocardium.
Reduced gene expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure.
Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies.
Selection of reference genes for gene expression studies in heart failure for left and right ventricles.
Hemochromatosis
Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes.
Hepatitis
Evaluation of hepatocyte-derived microRNA-122 for diagnosis of acute and chronic hepatitis of dogs.
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma.
Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitis.
Specific interaction between the hepatitis delta virus RNA and glyceraldehyde 3-phosphate dehydrogenase: an enhancement on ribozyme catalysis.
The hepatitis delta virus RNA genome interacts with eEF1A1, p54(nrb), hnRNP-L, GAPDH and ASF/SF2.
[Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference]
Hepatitis A
Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function.
Interaction of glyceraldehyde-3-phosphate dehydrogenase with secondary and tertiary RNA structural elements of the hepatitis A virus 3' translated and non-translated regions.
Specific interaction of glyceraldehyde 3-phosphate dehydrogenase with the 5'-nontranslated RNA of hepatitis A virus.
Hepatitis B
A yeast system for stable expression of hepatitis B surface antigen.
Controlled fed-batch fermentation of recombinant Saccharomyces cerevisiae to produce hepatitis B surface antigen.
Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model.
Expression of hepatitis B surface antigen in Saccharomyces cerevisiae utilizing glyceraldeyhyde-3-phosphate dehydrogenase promoter of Pichia pastoris
Expression of hepatitis B surface antigen in Saccharomyces cerevisiae utilizing glyceraldeyhyde-3-phosphate dehydrogenase promoter of Pichia pastoris.
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis.
Identification of glyceraldehyde-3-phosphate dehydrogenase as a cellular protein that binds to the hepatitis B virus posttranscriptional regulatory element.
Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis.
PCR Multiplexing Based on a Single Fluorescent Channel Using Dynamic Melting Curve Analysis.
Phosphorylation of the hepatitis B virus core protein by glyceraldehyde-3-phosphate dehydrogenase protein kinase activity.
Production of hepatitis B virion-like particles in yeast.
Role of glyceraldehyde-3-phosphate dehydrogenase binding to hepatitis B virus posttranscriptional regulatory element in regulating expression of HBV surface antigen.
[Optimization of cDNA microarray fabrication]
Hepatitis B, Chronic
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
Hepatitis C
HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons.
Human hepatic glyceraldehyde-3-phosphate dehydrogenase binds to the poly(U) tract of the 3' non-coding region of hepatitis C virus genomic RNA.
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells.
Hepatitis C, Chronic
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
Hepatitis, Alcoholic
Housekeeping gene variability in the liver of alcoholic patients.
Hepatitis, Chronic
Evaluation of hepatocyte-derived microRNA-122 for diagnosis of acute and chronic hepatitis of dogs.
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis.
Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use.
Hernias, Diaphragmatic, Congenital
Circulating cell-free fetal messenger RNA levels after fetoscopic interventions of complicated pregnancies.
Hodgkin Disease
Expression of housekeeping genes in Hodgkin's disease lymph nodes.
Huntington Disease
Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
Alteration of nuclear glyceraldehyde-3-phosphate dehydrogenase structure in Huntington's disease fibroblasts.
Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders.
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis.
GAPDH binders as potential drugs for the therapy of polyglutamine diseases: Design of a new screening assay.
Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.
Glyceraldehyde 3-phosphate dehydrogenase augments the intercellular transmission and toxicity of polyglutamine aggregates in a cell model of Huntington disease.
Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.
Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.
Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase.
Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington's disease.
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation.
Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Hypercholesterolemia
Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats.
Hyperglycemia
Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways.
Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1.
Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments.
Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy.
High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules.
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.
Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications.
Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells.
Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.
Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin.
Tissue-specific selection of stable reference genes for real-time PCR normalization in an obese rat model.
Type 2 diabetes mellitus: Role of melatonin and oxidative stress.
Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice.
Hyperinsulinism
The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows.
Hypersensitivity
Immunomodulatory effect of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in allergic conditions in vitro and in vivo.
Hypertension
Dietary capsaicin-mediated attenuation of hypertension in a rat model of renovascular hypertension.
Influence of pressure overload and ACE inhibitor therapy on constitutive protein mRNA expression in the spontaneously hypertensive rat.
Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling
Hypertension, Pulmonary
GAPDH is critical for superior efficacy of female bone marrow-derived mesenchymal stem cells on pulmonary hypertension.
Hypotension
[Does nitric oxide stress exist?]
Infarction, Middle Cerebral Artery
BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains.
Glyceraldehyde-3-phosphate dehydrogenase versus toluidine blue as a marker for infarct volume estimation following permanent middle cerebral artery occlusion in mice.
Induction of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression in rat brain after focal ischemia/reperfusion.
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Infections
?-Actin: Not a Suitable Internal Control of Hepatic Fibrosis Caused by Schistosoma japonicum.
A Panel of Stably Expressed Reference Genes for Real-Time qPCR Gene Expression Studies of Mallards (Anas platyrhynchos).
A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice.
Accumulation of cytosolic glyceraldehyde-3-phosphate dehydrogenase RNA under biological stress conditions and elicitor treatments in potato.
An improved infectivity assay combining cell culture with real-time PCR for rapid quantification of human adenoviruses 41 and semi-quantification of human adenovirus in sewage.
Anti-CTLA-4 monoclonal antibody improves efficacy of the glyceraldehyde-3-phosphate dehydrogenase protein vaccine against Schistosoma japonicum in mice.
Assessment of reference gene stability in Rice stripe virus and Rice black streaked dwarf virus infection rice by quantitative Real-time PCR.
Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores.
Changes in the contents of metabolites and enzyme activities in rice plants responding to Rhizoctonia solani Kuhn infection: activation of glycolysis and connection to phenylpropanoid pathway.
Citrobacter rodentium NleB Protein Inhibits Tumor Necrosis Factor (TNF) Receptor-associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production.
Clinical strains of Candida albicans express the surface antigen glyceraldehyde 3-phosphate dehydrogenase in vitro and in infected tissues.
Cloning and heterologous overexpression of three gap genes encoding different glyceraldehyde-3-phosphate dehydrogenases from the plant pathogenic bacterium Pseudomonas syringae pv. tomato strain DC3000.
Construction and immune effect of Haemophilus parasuis DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in mice.
Cytoskeletal Alteration Is an Early Cellular Response in Pulmonary Epithelium Infected with Aspergillus fumigatus Rather than Scedosporium apiospermum.
Dengue virus NS1 protein interacts with the ribosomal protein RPL18: this interaction is required for viral translation and replication in Huh-7 cells.
Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity.
Determination of suitable reference genes for RT-qPCR analysis of murine Cytomegalovirus in vivo and in vitro.
Development and validation of a multiplex qPCR assay for detection and relative quantification of HPV16 and HPV18 E6 and E7 oncogenes.
Development of species-specific IgM antibodies and elevation of mucosal immune response in Labeo rohita using recombinant bicistronic nano DNA vaccine priming.
Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells.
Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues.
Effect of acute infectious disease on human isometric muscle endurance.
Effects of a diabetogenic strain of encephalomyocarditis (EMC) virus on protein synthesis in mouse islets of Langerhans.
Evaluation and validation of reference gene stability during Marek's disease virus (MDV) infection.
Evaluation of reference genes for real-time PCR studies of Brazilian Somalis sheep infected by gastrointestinal nematodes.
Evaluation of the suitability of six host genes as internal control in real-time RT-PCR assays in chicken embryo cell cultures infected with infectious bursal disease virus.
Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model.
Excreted cytoplasmic proteins contribute to pathogenicity in Staphylococcus aureus.
Glyceraldehyde 3-phosphate dehydrogenase negatively regulates human immunodeficiency virus type 1 infection.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein.
Glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda has protective antigenicity against Vibrio anguillarum in Japanese flounder.
Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells.
Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression.
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Glyceraldehyde-3-phosphate dehydrogenase, an immunogenic Streptococcus equi ssp. zooepidemicus adhesion protein and protective antigen.
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy.
Hypoxia promotes Chlamydia trachomatis L2/434/Bu growth in immortal human epithelial cells via activation of the PI3K-AKT pathway and maintenance of a balanced NAD+/NADH ratio.
Identification and selection of normalization controls for quantitative transcript analysis in Blumeria graminis.
Identification of immunogenic proteins and evaluation of recombinant PDHA1 and GAPDH as potential vaccine candidates against Streptococcus iniae infection in flounder (Paralichthys olivaceus).
Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection.
Identification of Reference Genes in Chicken Intraepithelial Lymphocyte Natural Killer Cells Infected with Very-virulent Infectious Bursal Disease Virus.
Immunisation with Salmonella typhimurium-delivered glyceraldehyde-3-phosphate dehydrogenase protects mice against challenge infection with Echinococcus multilocularis eggs.
Immunoprotection of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Lactococcus garvieae against Lactococcosis in tilapia.
Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions.
Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis.
Induction of Protective Immune Responses Against Schistosomiasis haematobium in Hamsters and Mice Using Cysteine Peptidase-Based Vaccine.
Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment.
InterFeriNg with Acet?lation: Stress-Levels of Acetate Improve Memory T Cell Function.
Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53.
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells.
Mucosal immunisation with novel Streptococcus pneumoniae protein antigens enhances bacterial clearance in an acute mouse lung infection model.
Multiplex PCR as a tool for the diagnosis of Leishmania spp. kDNA and the gapdh housekeeping gene of mammal hosts.
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-?B activation.
Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase.
Proteome profiling of the dimorphic fungus Penicillium marneffei extracellular proteins and identification of glyceraldehyde-3-phosphate dehydrogenase as an important adhesion factor for conidial attachment.
Quantitative detection for low levels of Helicobacter pylori infection in experimentally infected mice by real-time PCR.
Real time PCR for monitoring regulation of host gene expression in herpes simplex virus type 1-infected human diploid cells.
Relative expression analysis of IL-5 and IL-6 genes in tropical sheep breed Pelibuey infected with Haemonchus contortus.
Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus.
Role of cytosolic glyceraldehyde-3-phosphate dehydrogenase in visceral organ infection by Leishmania donovani.
Role of secreted glyceraldehyde-3-phosphate dehydrogenase in the infection mechanism of enterohemorrhagic and enteropathogenic Escherichia coli: interaction of the extracellular enzyme with human plasminogen and fibrinogen.
Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture.
Selection and Validation of Suitable Reference Genes for RT-qPCR Analysis in Apolygus lucorum (Hemiptera: Miridae).
Selection of reference genes for gene expression studies in virus-infected monocots using quantitative real-time PCR.
Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus.
Surface Display of Aeromonas hydrophila GAPDH in Attenuated Vibrio anguillarum to Develop a Noval Multivalent Vector Vaccine.
Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus.
The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner.
Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways.
Translational control of viral and host protein synthesis during the course of herpes simplex virus type 1 infection: evidence that initiation of translation is the limiting step.
Vaccine efficacy of recombinant GAPDH of Edwardsiella tarda against Edwardsiellosis.
VACCINE-INDUCED PROTECTION AGAINST MURINE SCHISTOSOMIASIS MANSONI WITH LARVAL EXCRETORY-SECRETORY ANTIGENS AND PAPAIN OR TYPE-2 CYTOKINES.
Validation of reference genes for expression analysis in the salivary gland and the intestine of Rhodnius prolixus (Hemiptera, Reduviidae) under different experimental conditions by quantitative real-time PCR.
Validation of reference genes for quantifying changes in gene expression in virus-infected tobacco.
Validation of superior reference genes for qRT-PCR and Western blot analyses in marine Emiliania huxleyi-virus model system.
Infertility
Anti-GAPDHS antibodies: a biomarker of immune infertility.
Approaches to post-testicular contraception.
Plastidial glyceraldehyde-3-phosphate dehydrogenase deficiency leads to altered root development and affects the sugar and amino Acid balance in Arabidopsis.
Infertility, Male
Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray.
The plastidial glyceraldehyde-3-phosphate dehydrogenase is critical for viable pollen development in Arabidopsis.
Inflammatory Bowel Diseases
5-aminosalicylic acid prevents oxidant mediated damage of glyceraldehyde-3-phosphate dehydrogenase in colon epithelial cells.
Elucidation of colon-protective efficacy of diosgenin in experimental TNBS-induced colitis: inhibition of NF-?B/IkB-? and Bax/Caspase-1 signaling pathways.
The Effect of IL-26 on TNF-?-Induced CXCL8 Responses by Colonic Epithelial Cell Lines.
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
Influenza, Human
18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells.
On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: Potential implications for biological management of adenocarcinomas.
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza.
Typing (A/B) and subtyping (H1/H3/H5) of influenza A viruses by multiplex real-time RT-PCR assays.
Insulin Resistance
Association Between First Episode Schizophrenia, Metabolic Syndrome and Insulin Resistance-Related Proteins in Female Balb/C Mice.
Expression of the receptor of advanced glycation end-products (RAGE) and membranal location in peripheral blood mononuclear cells (PBMC) in obesity and insulin resistance.
Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.
Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy.
Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance.
Intellectual Disability
A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe.
Intestinal Volvulus
Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH).
DNA vaccine encoding the moonlighting protein Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH) leads to partial protection in a mouse model of human filariasis.
Iron Deficiencies
The effect of iron status on glyceraldehyde 3-phosphate dehydrogenase expression in rat liver.
Ischemic Stroke
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Keratoconus
Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients.
Kidney Neoplasms
Novel insight into the role of GAPDH playing in tumor.
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
[Novel reference gene RPN1 for normalization of quantitative data in lung and kidney cancer].
Laryngeal Neoplasms
Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx.
Leiomyoma
Expression of a mitochondrial progesterone receptor (PR-M) in leiomyomata and association with increased mitochondrial membrane potential.
mRNA-expression of often used house-keeping genes and the relation between RNA and DNA are sex steroid-dependent parameters in human myometrium and fibroids.
Leukemia
Characterization of an immortalized oviduct cell line from the cynomolgus monkey (Macaca fascicularis).
Digital quantification of gene expression using emulsion PCR.
Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs.
Loss of Pax5 exploits Sca1-BCR-ABLp190 susceptibility to confer the metabolic shift essential for pB-ALL.
Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia.
Structure/function in neuroprotection and apoptosis.
Urea-nuclease treatment of concentrated retrovirions preserves viral RNA and removes polymerase chain reaction-amplifiable cellular RNA and DNA.
[RT-PCR detecting NUP98-HOX fusion gene in leukemia]
[Significance of dynamic detection of WT1 expression on monitoring minimal residual disease in leukemia patients following allogeneic bone marrow transplantation]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia.
Gene Expression upon Proliferation and Differentiation of Hematopoietic Cells with Ph Chromosome ex vivo.
Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase.
Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia.
Listeriosis
Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH.
Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase.
Liver Cirrhosis
Down-regulation of hepatic and renal 11 beta-hydroxysteroid dehydrogenase in rats with liver cirrhosis.
High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis.
Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis.
Liver Diseases
Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection.
High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis.
Mycobacterial DNA not detected in liver sections from patients with primary biliary cirrhosis.
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB.
Liver Neoplasms
Analysis of Key Genes Regulating the Warburg Effect in Patients with Gastrointestinal Cancers and Selective Inhibition of This Metabolic Pathway in Liver Cancer Cells.
CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer.
Novel insight into the role of GAPDH playing in tumor.
Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR.
Lung Diseases
PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells.
Lung Injury
Identification of differentially expressed proteins in the injured lung from zinc chloride smoke inhalation based on proteomics analysis.
Lung Neoplasms
A sequence-based approach to identify reference genes for gene expression analysis.
Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells.
ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology.
BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
Choice of endogenous control for gene expression in nonsmall cell lung cancer.
Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPK? signaling in STK11 mutant lung cancer.
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR.
Direct Binding of Glyceraldehyde 3-Phosphate Dehydrogenase to Telomeric DNA Protects Telomeres against Chemotherapy-Induced Rapid Degradation.
Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers.
Gene expression of somatostatin receptor subtypes SSTR2a, SSTR3 and SSTR5 in peripheral blood of neuroendocrine lung cancer affected patients.
Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients.
Novel insight into the role of GAPDH playing in tumor.
PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy.
Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure.
Similarity between glyceraldehyde-3-phosphate dehydrogenase and a 37,000-dalton protein which is abundantly expressed in human lung cancers.
Simultaneous down-regulation of tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer.
The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors.
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
Lyme Disease
A glyceraldehyde-3-phosphate dehydrogenase homolog in Borrelia burgdorferi and Borrelia hermsii.
Lymphoma
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1?
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-?B-Dependent Mechanism.
Glycolytic biomarkers predict transformation in patients with follicular lymphoma.
Investigation of the expression of housekeeping genes in non-Hodgkin's lymphoma.
Molecular characterization of BCL6 breakpoints in primary diffuse large B-cell lymphomas of the central nervous system identifies GAPD as novel translocation partner.
Sirt1/Nrf2 signalling pathway prevents cognitive impairment in diabetic rats through anti?oxidative stress induced by miRNA?23b?3p expression.
Tumor hypoxia and metabolism -- towards novel anticancer approaches.
Lymphoma, B-Cell
Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
Lymphoma, Non-Hodgkin
GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1?
Lymphoma, T-Cell
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-?B-Dependent Mechanism.
Glutathione-garlic sulfur conjugates: slow hydrogen sulfide releasing agents for therapeutic applications.
Macular Degeneration
Studies on the mechanism of early onset macular degeneration in cynomolgus (Macaca fascicularis) monkeys. I. Abnormal concentrations of two proteins in the retina.
Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress.
Malaria
Direct RNA detection without nucleic acid purification and PCR: Combining sandwich hybridization with signal amplification based on branched hybridization chain reaction.
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria.
Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion.
Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection.
Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target.
Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
Malnutrition
Prolactin receptor gene expression and foetal adipose tissue.
The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows.
Marek Disease
Evaluation and validation of reference gene stability during Marek's disease virus (MDV) infection.
Mastitis
Characterization of two proteins of Staphylococcus aureus isolated from bovine clinical mastitis with homology to glyceraldehyde-3-phosphate dehydrogenase.
Technical note: Validation of candidate reference genes for normalization of quantitative PCR in bovine mammary epithelial cells responding to inflammatory stimuli.
Melanoma
Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma.
Detecting homozygous deletions in the CDKN2A(p16(INK4a))/ARF(p14(ARF)) gene in urinary bladder cancer using real-time quantitative PCR.
Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases.
Gene expression profiling of melanocytic lesions.
Glyceraldehyde-3-phosphate dehydrogenase expression is altered by hypoxia in melanoma cells and primary human melanocytes.
Hypoxia-induced HIF1? targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis.
Identification of robust reference genes for studies of gene expression in FFPE melanoma samples and melanoma cell lines.
Isolation of tumorigenic circulating melanoma cells.
Novel insight into the role of GAPDH playing in tumor.
Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma.
Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations.
Sensitivity to extrinsically supplied interferon and the endogenous expression of interferon in melanoma cell lines.
Sperm-specific glyceraldehyde-3-phosphate dehydrogenase is expressed in melanoma cells.
Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis.
The Highlighted Role of GAPDH and Nitric-Oxide Synthase Regulator Activity in Proton Beam Irradiated Melanoma BLM Cells.
The normalization of gene expression data in melanoma: investigating the use of glyceraldehyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for quantitative real-time PCR.
[Expression of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in melanoma cells changes their energy metabolism].
Melanoma, Experimental
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Memory Disorders
Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-? Aggregation and Cytotoxicity.
Meningioma
Selection of suitable reference genes for quantitative real-time polymerase chain reaction in human meningiomas and arachnoidea.
Validation of Reference Genes for Expression Studies in Human Meningiomas under Different Experimental Settings.
VEGF-A mRNA measurement in meningiomas using a new simplified approach: branched DNA and chemiluminescence.
Meningitis
Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes.
Metabolic Syndrome
New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells.
Microphthalmos
Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter.
Microvascular Angina
Altered transcriptional activity of gene encoding GAPDH in peripheral blood mononuclear cells from patients with cardiac syndrome X - an important part in pathology of microvascular angina?
Motor Neuron Disease
Effects of gene therapy on muscle 18S rRNA expression in mouse model of ALS.
Movement Disorders
Reduction of GAPDH in lenses of Parkinson's disease patients: A possible new biomarker.
Mucopolysaccharidoses
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.
Multiple Myeloma
MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4.
Multiple Sclerosis
Identification of Suitable Reference Genes for Peripheral Blood Mononuclear Cell Subset Studies in Multiple Sclerosis.
Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with multiple sclerosis.
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.
Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease.
Muscle Spasticity
Tail muscle parvalbumin content is decreased in chronic sacral spinal cord injured rats with spasticity.
Muscular Atrophy
Proteomic analysis of muscle affected by motor neuron degeneration: The wobbler mouse model of amyotrophic lateral sclerosis.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Muscular Diseases
Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid.
Mycoses
Evaluation of Reference Genes for Reverse Transcription Quantitative PCR Studies of Physiological Responses in the Ghost Moth, Thitarodes armoricanus (Lepidoptera, Hepialidae).
Selection of optimized candidate reference genes for qRT-PCR normalization in rice (Oryza sativa L.) during Magnaporthe oryzae infection and drought.
Myocardial Infarction
Decreased expression of cardiac sarcoplasmic reticulum Ca(2+)-pump ATPase in congestive heart failure due to myocardial infarction.
Increased Expression Level of Long Noncoding RNA H19 in Plasma of Patients with Myocardial Infarction.
Relation between expression of TNF alpha, iNOS, VEGF mRNA and development of heart failure after experimental myocardial infarction in rats.
Validation of reference genes for the determination of platelet transcript level in healthy individuals and in patients with the history of myocardial infarction.
Myocardial Ischemia
Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.
Myocarditis
[Selection of reference genes for transcription analysis for myocarditis studies].
Myoclonic Epilepsies, Progressive
Glyceraldehyde 3-phosphate dehydrogenase and endothelin-1 immunoreactivity is associated with cerebral white matter damage in dentatorubral-pallidoluysian atrophy.
Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases.
nad(p)h oxidase (h2o2-forming) deficiency
Novel effect of oxidized low-density lipoprotein: cellular ATP depletion via downregulation of glyceraldehyde-3-phosphate dehydrogenase.
Nasal Polyps
Expression of neutrophil gelatinase-associated lipocalin in nasal polyps.
[Relationship between expressions of GATA-3 and interleukin-5 in nasal polyps]
Nasopharyngeal Carcinoma
MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.
Neoplasm Metastasis
Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis.
BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases.
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway.
Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases.
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression.
Human-specific GAPDH qRT-PCR is an accurate and sensitive method of xenograft metastasis quantification.
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review.
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.
Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases.
Single-cell protein profiling in microchambers with barcoded beads.
Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities.
There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue.
Neoplasms
2-Deoxyglucose and Newcastle Disease Virus Synergize to Kill Breast Cancer Cells by Inhibition of Glycolysis Pathway Through Glyceraldehyde3-Phosphate Downregulation.
3-Bromopyruvate as a potential pharmaceutical in the light of experimental data.
3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines.
3-Bromopyruvate-Conjugated Nanoplatform-Induced Pro-Death Autophagy for Enhanced Photodynamic Therapy against Hypoxic Tumor.
A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA.
A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR?125b binding site.
A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR.
A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation.
A reverse transcription-quantitative competitive polymerase chain reaction (RT-qcPCR) technique to measure cytokine gene expression in domestic mammals.
A sequence-based approach to identify reference genes for gene expression analysis.
Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors.
Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro.
Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells.
Acetyl Eburicoic Acid from Laetiporus sulphureus var. miniatus Suppresses Inflammation in Murine Macrophage RAW 264.7 Cells.
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
Acute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy.
Affinity-Driven Covalent Modulator of the Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Cascade.
Alteration of GLIS3 gene expression pattern in patients with breast cancer.
Alteration of glyceraldehyde-3-phosphate dehydrogenase activity and messenger RNA content by androgen in human prostate carcinoma cells.
Alterations of repeated sequences in 5' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome.
Aminoquinolines as Translational Models for Drug Repurposing: Anticancer Adjuvant Properties and Toxicokinetic-Related Features.
Analyzing time-series microarray data reveals key genes in spinal cord injury.
Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines.
Antitumor Efficacy and Mechanism in Hepatoma H22-Bearing Mice of Brucea javanica Oil.
Association of Cone-Rod Homeobox Transcription Factor Messenger RNA With Pediatric Metastatic Retinoblastoma.
Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma.
Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis.
Basic Biology of GAPDH.
Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas.
Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis.
Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer.
C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia.
Calcium Fructoborate Prevents Skin Cancer Development in Balb-c Mice: Next Part, Reverse Inflammation, and Metabolic Alteration.
Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism.
Chaperonin-Dendrimer Conjugates for siRNA Delivery.
Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells.
Chemical targeting of GAPDH moonlighting function in cancer cells reveals its role in tubulin regulation.
Choice of endogenous control for gene expression in nonsmall cell lung cancer.
Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling.
Competitive method-based electrochemiluminescent assay with protein-nucleotide conversion for ratio detection to efficiently monitor the drug resistance of cancer cells.
Consensus reference gene(s) for gene expression studies in human cancers: end of the tunnel visible?
Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes.
Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor.
Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma.
Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.
Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation.
Critical protein GAPDH and its regulatory mechanisms in cancer cells.
Cytokine Expression by Human Macrophage-Like Cells Derived from the Monocytic Cell Line THP-1 Differs Between Treatment With Milk from Preterm- and Term-Delivering Mothers and Pasteurized Donor Milk.
Cytokine gene signatures in neural tissue of horses with equine protozoal myeloencephalitis or equine herpes type 1 myeloencephalopathy.
Cytokine mRNA quantification in duodenal mucosa from dogs with chronic enteropathies by real-time reverse transcriptase polymerase chain reaction.
Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy.
Cytotoxicity of chemotherapeutic agents in glyceraldehyde-3-phosphate dehydrogenase-depleted human lung carcinoma A549 cells with the accelerated senescence phenotype.
Decreased expression of cytochromes P450 1A2, 2E1, and 3A4 and drug transporters Na+-taurocholate-cotransporting polypeptide, organic cation transporter 1, and organic anion-transporting peptide-C correlates with the progression of liver fibrosis in chronic hepatitis C patients.
Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma.
Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target.
Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells.
Detection and quantitation of circulating cancer cells in the peripheral blood of lung cancer patients.
Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva.
Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting Warburg effect.
Development and validation of cytokine quantitative, real time RT-PCR assays for characterization of Asian elephant immune responses.
DEVELOPMENT AND VALIDATION OF QUANTITATIVE PCR ASSAYS TO MEASURE CYTOKINE TRANSCRIPT LEVELS IN THE FLORIDA MANATEE ( TRICHECHUS MANATUS LATIROSTRIS).
Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies.
Diagnostic and prognostic value of the detection of hTERT mRNA in renal tumors.
Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker.
Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy.
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells.
Differential display and integrin alpha 6 messenger RNA overexpression in hepatocellular carcinoma.
Direct comparison of GAPDH, beta-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia.
Discovery of novel glyceraldehyde-3-phosphate dehydrogenase inhibitor via docking-based virtual screening.
Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases.
Disruption of NAD(+) binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions.
Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress.
Dissociation between tumor shrinkage and hormonal response during somatostatin analog treatment in an acromegalic patient: preferential expression of somatostatin receptor subtype 3.
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.
Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway.
Dysregulated bioenergetics: a key regulator of joint inflammation.
Ectophosphatase activity in the triple-negative breast cancer cell line MDA-MB-231.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis.
Elucidation of colon-protective efficacy of diosgenin in experimental TNBS-induced colitis: inhibition of NF-?B/IkB-? and Bax/Caspase-1 signaling pathways.
Enhanced gene expression in breast cancer cells in vitro and tumors in vivo.
Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase.
Enzyme activities at the surface of intact Ehrlich tumor cells with albumin in the isotonic assay medium.
Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas.
Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-?.
Evolution of GAPDH as a druggable target of tumor glycolysis?
Expression of a heptelidic acid-insensitive recombinant GAPDH from Trichoderma virens, and its biochemical and biophysical characterization.
Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development.
Expression of estrogen receptor (ER) subtypes and ERbeta isoforms in colon cancer.
Expression of MMP-10 in lung cancer.
Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion.
Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues.
Expression of vascular endothelial growth factor isoforms and platelet-derived endothelial cell growth factor in bladder cancer.
Expression Profile and Subcellular Localization of GAPDH in the Smooth Muscle Cells of Human Atherosclerotic Plaque: An Immunohistochemical and Ultrastructural Study with Biological Therapeutic Perspectives.
Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies.
Expression, purification and characterization of GAPDH-ChSase ABC I from Proteus vulgaris in Escherichia coli.
Functional and molecular characterization of glioblastoma multiforme-derived cancer stem cells.
GAPDH and PUM1: Optimal Housekeeping Genes for Quantitative Polymerase Chain Reaction-Based Analysis of Cancer Stem Cells and Epithelial-Mesenchymal Transition Gene Expression in Rectal Tumors.
GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.
GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1?
GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors.
GAPDH is not regulated in human glioblastoma under hypoxic conditions.
GAPDH with NAD+-binding site mutation competitively inhibits the wild-type and affects glucose metabolism in cancer.
Gene expression profiles in thyroid carcinomas.
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes.
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death.
Glyceraldehyde-3-phosphate dehydrogenase and other enzymatic activity in normal mouse lung and in lung tumors.
Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype.
Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer.
Glyceraldehyde-3-phosphate dehydrogenase is a microtubule binding protein in a human colon tumor cell line.
Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal.
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression.
Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase.
Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma.
Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity.
Glypican-3 mRNA expression level in Wilms tumor: correlation with histological type, stage, and outcome.
GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity.
HCV RNA levels in hepatocellular carcinomas and adjacent non-tumorous livers.
HDM2-binding partners: interaction with translation elongation factor EF1alpha.
High bad and bcl-xL gene expression and combined bad, bcl-xL, bax and bcl-2 mRNA levels: molecular predictors for survival of stage 2 soft tissue sarcoma patients.
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
High level of ezrin mRNA expression in an osteosarcoma biopsy sample with lung metastasis.
Higher tumor to benign ratio of the androgen receptor mRNA expression associates with prostate cancer progression after radical prostatectomy.
Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.
HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy.
Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.
Hypoxia-induced tumor cell resistance is overcome by synergistic GAPDH-siRNA and chemotherapy co-delivered by long-circulating and cationic-interior liposomes.
Identification and Quantification of Transient Receptor Potential Vanilloid 1 (TRPV1) in Equine Articular Tissue.
Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter.
Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer.
Identification of GAPDH as a protein target of the saframycin antiproliferative agents.
Identification of human serum protein targets of Qianggu Decoction () in primary type I osteoporosis based on tandem mass tag labeling and liquid chromatography-tandem mass spectrometry technology.
Identification of key genes implicated in the suppressive function of human FOXP3+CD25+CD4+ regulatory T cells through the analysis of time?series data.
Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins.
Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization.
Identification of valid endogenous control genes for determining gene expression in human glioma.
Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study group.
IGF1R gene expression as a predictive marker of response to ionizing radiation for patients with locally advanced HPV16-positive cervical cancer.
In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development.
Inactivation of glyceraldehyde-3-phosphate dehydrogenase of human malignant cells by methylglyoxal.
Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions.
Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.
Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer.
Increased translocator protein (TSPO) mRNA levels in colon but not in rectum carcinoma.
Inferring genome-wide functional modulatory network: a case study on NF-?B/RelA transcription factor.
Influenza virus infection elicits protective antibodies and T cells specific for host cell antigens also expressed as tumor-associated antigens: a new view of cancer immunosurveillance.
Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats.
Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase.
Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells.
Isolation and characterization of complementary DNA clones corresponding to genes induced in mouse epidermis in vivo by tumor promoters.
Keratinocyte autophagy enables the activation of keratinocytes and fibroblasts and facilitates wound healing.
Lactate does not activate NF-?B in oxidative tumor cells.
Localization of non-native D-glyceraldehyde-3-phosphate dehydrogenase in growing and apoptotic HeLa cells.
Metabolic markers and HSP60 in chemonaive serous solid ovarian cancer versus ascites.
MicroRNA let-7i-3p affects osteoblast differentiation in ankylosing spondylitis via targeting PDK1.
MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics.
Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells.
Modulation of glyceraldehyde-3-phosphate dehydrogenase activity by surface functionalized quantum dots.
Modulation of immunity and inflammatory gene expression in buffalo (Bubalus bubalis) with some digestive disorders.
Modulatory effect of mycobacterium cell wall extract (Regressin) on lymphocyte blastogenic activity and macrophage cytokine gene transcription in swine.
Modulatory roles of glycolytic enzymes in cell death.
Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer.
Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells.
Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase.
Molecular diagnosis of sentinel lymph node metastases in cervical cancer using squamous cell carcinoma antigen.
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity.
Natural product 1,2,3,4,6-penta-O-galloyl-?-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.
Nitroxyl inhibits breast tumor growth and angiogenesis.
Novel insight into the role of GAPDH playing in tumor.
Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior.
On the Relevance of Glycolysis Process on Brain Gliomas.
Overexpression of osteopontin in hepatocellular carcinoma.
Pan-Cancer Analysis of TCGA Data Revealed Promising Reference Genes for qPCR Normalization.
Partial volume rat lung irradiation: Temporal fluctuations of in-field and out-of-field DNA damage and inflammatory cytokines following irradiation.
Persistence of multiple tumor-specific T-cell clones is associated with complete tumor regression in a melanoma patient receiving adoptive cell transfer therapy.
Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications.
Pharmacological targets and molecular mechanisms of plumbagin to treat colorectal cancer: A systematic pharmacology study.
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.
Platyphylloside Isolated From Betula platyphylla Inhibit Adipocyte Differentiation and Induce Lipolysis Via Regulating Adipokines Including PPAR? in 3T3-L1 Cells.
Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases.
Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease.
Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx.
Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study.
Progesterone Treatment Attenuates Glycolytic Metabolism and Induces Senescence in Glioblastoma.
Properties of the glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites tumor cells.
Protective effects of Toll-like receptor 4 inhibitor eritoran on renal ischemia-reperfusion injury.
Protein and gene expression of tumor-associated antigen RCAS1 in esophageal squamous cell carcinoma.
Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer.
Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathways.
Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia.
Quantitation of estrogen receptor mRNA copy numbers in breast cancer cell lines and tumors.
Quantitation of O6-methylguanine-DNA methyltransferase gene messenger RNA in gliomas by means of real-time RT-PCR and clinical response to nitrosoureas.
Quantitation of vascular endothelial growth factor mRNA levels in human breast tumors and metastatic lymph nodes.
Quantitative PCR analysis of c-erb B-2 (HER2/neu) gene amplification and comparison with p185(HER2/neu) protein expression in breast cancer drill biopsies.
Quantitative real-time RT-PCR measurement of cytokine mRNA expression in the skin of normal cats and cats with allergic skin disease.
Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure.
Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers.
Reduced plasma RNA integrity in nasopharyngeal carcinoma patients.
Reference gene selection for head and neck squamous cell carcinoma gene expression studies.
Reference gene selection for quantitative real-time reverse-transcriptase PCR in orchardgrass subjected to various abiotic stresses.
Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders.
Relative down-regulation of apoptosis and autophagy genes in colorectal cancer.
Relative quantification of BCL2 mRNA for diagnostic usage needs stable uncontrolled genes as reference.
Removing the cells from adult bone marrow derived stem cell therapy does not eliminate cardioprotection.
Retinoic acid receptors alpha, beta and gamma, and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer.
Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling
Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations.
Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion.
Selection of an internal control gene for quantitation of mRNA in colonic tissues.
Selection of candidate housekeeping controls in tomato plants using EST data.
Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme.
Single-cell protein profiling in microchambers with barcoded beads.
Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease.
Smoking Modulates Gene Expression of Type I Collagen, Bone Sialoprotein, and Osteocalcin in Human Alveolar Bone.
Stressors Due to Handling Impair Gut Immunity in Meagre (Argyrosomus regius): The Compensatory Role of Dietary L-Tryptophan.
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNF?-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction.
Structural Study of Monomethyl Fumarate-Bound Human GAPDH.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities.
Technical note: Validation of candidate reference genes for normalization of quantitative PCR in bovine mammary epithelial cells responding to inflammatory stimuli.
Telomerase RNA as a detection marker in the serum of breast cancer patients.
The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma.
The diverse functions of GAPDH: Views from different subcellular compartments.
The Effect of Bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene?
The Effect of IL-26 on TNF-?-Induced CXCL8 Responses by Colonic Epithelial Cell Lines.
The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
The mitochondrial bioenergetic capacity of carcinomas.
The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
The role of posttranslational modification in moonlighting glyceraldehyde-3-phosphate dehydrogenase structure and function.
There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue.
Thioredoxin, a regulator of gene expression.
Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala).
TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer.
Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways.
Transcriptional profiling of cell lines derived from an orthotopic pancreatic tumor model reveals metastasis-associated genes.
Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2.
Tumor hypoxia and metabolism -- towards novel anticancer approaches.
Two-stage hepatectomy with effective perioperative chemotherapy does not induce tumor growth or growth factor expression in liver metastases from colorectal cancer.
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism.
Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.
Up-regulation of Key Glycolysis Proteins in Cancer Development.
Upregulation of glyceraldehyde-3-phosphate dehydrogenase mRNA in the spleen of tumor-bearing mice.
Validation of common reference genes stability in exosomal mRNA-isolated from liver and breast cancer cell lines.
Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR.
Vitamin C Targets GAPDH to Kill KRAS- and BRAF-Mutant Cancer Cells.
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
[Expression of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in melanoma cells changes their energy metabolism].
[Monitoring IgH levels in patients with B-cell malignancy by real-time quantitative PCR after hematopoietic stem cell transplantation and its significance]
[Proteomic analysis of morphine rabbit myocardium with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry]
[Quantitative analysis of epidermal growth factor receptor mRNA in laryngeal carcinoma by reverse transcription-real time polymerase chain reaction with TagMan probe]
[Selection and quantitative detection of target genes in oral squamous cell carcinoma]
[The vascular endothelial growth factor in patients with advanced ovarian cancer on the background of chemotherapy according to the AP scheme.]
Neoplastic Cells, Circulating
Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study.
Nephritis, Hereditary
Expression of type IV collagen alpha 3 and alpha 4 chain mRNA in X-linked Alport syndrome.
Nephrosis
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Nephrotic Syndrome
Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy.
Nervous System Diseases
Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease.
Neuralgia
Identification and validation of reference genes for expression studies in a rat model of neuropathic pain.
Proteomic analysis of differential proteins related to the neuropathic pain and neuroprotection in the dorsal root ganglion following its chronic compression in rats.
Neuroblastoma
A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.
A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine.
Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death.
Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure.
An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells.
Development of a real-time polymerase chain reaction assay for prediction of the uptake of meta-[(131)I]iodobenzylguanidine by neuroblastoma tumors.
DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis.
Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues.
GAPDH siRNA Regulates SH-SY5Y Cell Apoptosis Induced by Exogenous ?-Synuclein Protein.
GAPDH-targeted therapy - A new approach for secondary damage after traumatic brain injury on rats.
Homocysteine induces glyceraldehyde-3-phosphate dehydrogenase acetylation and apoptosis in the neuroblastoma cell line Neuro2a.
Melatonin alters the metabolism of the beta-amyloid precursor protein in the neuroendocrine cell line PC12.
NK sensitivity of neuroblastoma cells determined by a highly sensitive coupled luminescent method.
Novel mechanism of Hsp70 chaperone-mediated prevention of polyglutamine aggregates in a cellular model of huntington disease.
Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury.
Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis.
Possible involvement of ADP-ribosylation of particular enzymes in cell death induced by nitric oxide-donors in human neuroblastoma cells.
Prolyl oligopeptidase participates in the cytosine arabinoside-induced nuclear translocation of glyceraldehyde 3-phosphate dehydrogenase in a human neuroblastoma cell line.
Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells.
Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma.
Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery.
Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Neurodegenerative Diseases
A Proteomic Approach for the Involvement of the GAPDH in Alzheimer Disease in the Blood of Moroccan FAD Cases.
Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease.
Effect of Resveratrol and Tiron on The Inactivation of Glyceraldehyde-3-Phosphate Dehydrogenase Induced by Superoxide Anion Radical.
Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis.
GAPDH as a sensor of NO stress.
Glycation of ?-synuclein amplifies the binding with glyceraldehyde-3-phosphate dehydrogenase.
Glycation of glyceraldehyde-3-phosphate dehydrogenase inhibits the binding with ?-synuclein and RNA.
Glyceraldehyde-3-phosphate dehydrogenase and apoptosis.
Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.
Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates.
Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling.
Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases.
Glyceraldehyde-3-phosphate dehydrogenase: Aggregation mechanisms and impact on amyloid neurodegenerative diseases.
Increased expression of GAPDH in cynomolgus monkeys with spontaneous cognitive decline and amyloidopathy reminiscent of an Alzheimer's-type disease is reflected in the circulation.
Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation.
Moonlighting glyceraldehyde-3-phosphate dehydrogenase: posttranslational modification, protein and nucleic acid interactions in normal cells and in human pathology.
Multiple binding partners.
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.
Nuclear translocation and accumulation of glyceraldehyde-3-phosphate dehydrogenase involved in diclazuril-induced apoptosis in Eimeria tenella (E. tenella).
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation.
Proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase: a possible site of action of antiapoptotic drugs.
Properties and functional diversity of glyceraldehyde-3-phosphate dehydrogenase.
Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse.
Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts.
Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders.
Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology.
Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease.
Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase.
Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing ?-synuclein Oligomeric Species Toxicity.
Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts.
The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death.
The biological significance of oxidative modifications of cysteine residues in proteins illustrated with the example of glyceraldehyde-3-phosphate dehydrogenase.
The diverse functions of GAPDH: Views from different subcellular compartments.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
[Oxidative modification of glyceraldehyde-3-phosphate dehydrogenase influences its interaction with endogenous neuroprotector isatin].
[The biological significance of oxidative modifications of cysteine residues in proteins illustrated with the example of glyceraldehyde-3-phosphate dehydrogenase].
Neuroectodermal Tumors, Primitive, Peripheral
Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip.
Neuroendocrine Tumors
ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology.
GeneChip, geNorm, and gastrointestinal tumors: novel reference genes for real-time PCR.
Nevus
Gene expression profiling of melanocytic lesions.
Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma.
Non-alcoholic Fatty Liver Disease
Protein interaction mapping interpretation of none alcoholic fatty liver disease model of rats after fat diet feeding.
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB.
Obesity
Adipose-tissue-specific increase in glyceraldehyde-3-phosphate dehydrogenase activity and mRNA amounts in suckling pre-obese Zucker rats. Effect of weaning.
An overview on recent in vivo biological application of cerium oxide nanoparticles.
Comparative secretome analysis of rat stomach under different nutritional status.
Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.
High-Fat Diet Alters the Expression of Reference Genes in Male Mice.
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB.
[Apolipoprotein E gene expression in peripheral blood monocyte in children with obesity]
Onchocerciasis
Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH).
Oncogene Addiction
Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.
Osteoarthritis
Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain.
Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro.
Osteophyte
Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats.
Osteoporosis
Identification of human serum protein targets of Qianggu Decoction () in primary type I osteoporosis based on tandem mass tag labeling and liquid chromatography-tandem mass spectrometry technology.
Osteosarcoma
Analyzing time-series microarray data reveals key genes in spinal cord injury.
Biological evaluation of chitosan nanofiber membrane for guided bone regeneration.
Decreased long non-coding RNA lincFOXF1 indicates poor progression and promotes cell migration and metastasis in osteosarcoma.
Identification of valid reference housekeeping genes for gene expression analysis in tumor neovascularization studies.
Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines.
[Corrigendum] Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway.
Ovarian Neoplasms
A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR?125b binding site.
Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation.
Cytosolic and Transmembrane Protein Extraction Methods of Breast and Ovarian Cancer Cells: A Comparative Study.
Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype.
Metabolic markers GAPDH, PKM2, ATP5B and BEC-index in advanced serous ovarian cancer.
Quantification of total plasma cell-free DNA in ovarian cancer using real-time PCR.
Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response.
The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer.
Pancreatic Neoplasms
Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer.
Comparative peptidome profiling reveals critical roles for peptides in the pathology of pancreatic cancer.
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity.
Novel insight into the role of GAPDH playing in tumor.
Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer.
Ribosomal highly basic 23-kDa protein as a reliable standard for gene expression analysis.
Pancreatitis
Pancreatic GAPDH gene expression during ontogeny and acute pancreatitis induced by caerulein.
Pancreatitis, Chronic
Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer.
Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides.
Ribosomal highly basic 23-kDa protein as a reliable standard for gene expression analysis.
Papilloma
On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: Potential implications for biological management of adenocarcinomas.
Paralysis
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in tissues of the rat by acrylamide and related compounds.
Unimpaired energy metabolism in experimental neuropathy induced by p-bromophenylacetylurea.
Paramyxoviridae Infections
Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and LA protein with cis-acting RNAs of human parainfluenza virus type 3.
Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro.
Parasitic Diseases
Development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies.
Enhancing the Stability of Haemonchus contortus Glyceraldehyde-3-Phosphate Dehydrogenase and Binding of Host Albumin to the Parasite Enzyme.
Production of Sm37-GAPDH, a major therapeutical target in human schistosomiasis.
Parathyroid Neoplasms
Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism.
Parkinson Disease
A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons.
Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice.
Age-dependent accumulation of oligomeric SNCA/?-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme.
Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in ?-synuclein aggregation.
Deprenyl enhances the teratogenicity of hydroxyurea in organogenesis stage mouse embryos.
GAPDH as a sensor of NO stress.
GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease.
Genetic variants in GAPDH confer susceptibility to sporadic Parkinson's disease in a Chinese Han population.
Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.
Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease.
Identification of tyrosine nitration in UCH-L1 and GAPDH.
Inactivation of glyceraldehyde-3-phosphate dehydrogenase by the dopamine metabolite, 3,4-dihydroxyphenylacetaldehyde.
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease.
Novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase: covalent modification of NAD-binding site by aromatic thiols.
Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease.
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation.
Parkinson disease: GAPDH mutations can increase or decrease the risk of PD.
Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease.
Reduction of GAPDH in lenses of Parkinson's disease patients: A possible new biomarker.
Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease.
Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing ?-synuclein Oligomeric Species Toxicity.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Parkinsonian Disorders
Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation.
Peripheral Nerve Injuries
Quantification of Gene Expression after Painful Nerve Injury: Validation of Optimal Reference Genes.
Persistent Hyperplastic Primary Vitreous
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease.
Pheochromocytoma
Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease.
[Expression of adrenomedullin and its receptor mRNA in the tissues of normal adrenal medulla and pheochromocytoma]
Phytoplasma Disease
The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthoraperniciosa, the causal agent of witches' broom disease of Theobroma cacao.
Pituitary Neoplasms
Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion.
Pneumococcal Infections
Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.
Subcutaneous immunization with Streptococcus pneumoniae GAPDH confers effective protection in mice via TLR2 and TLR4.
Pneumonia
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza.
Pneumonia, Pneumocystis
Evaluation of a real-time PCR assay for the diagnosis of Pneumocystis pneumonia.
Polycystic Kidney Diseases
Abnormal glyceraldehyde-3-phosphate dehydrogenase binding and glycolytic flux in Autosomal Dominant Polycystic Kidney Disease after a mild oxidative stress.
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
Polycystic Kidney, Autosomal Dominant
Abnormal glyceraldehyde-3-phosphate dehydrogenase binding and glycolytic flux in Autosomal Dominant Polycystic Kidney Disease after a mild oxidative stress.
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
Porcine Reproductive and Respiratory Syndrome
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Pre-Eclampsia
Altered mRNA expression of ecNOS and iNOS in myometrium and placenta from women with preeclampsia.
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.
LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis.
PP011. Increased placental expression of angiogenin inhibitor (Ribonuclease inhibitor), a novel gene in pre-eclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A novel protein complex distinct from mismatch repair binds thioguanylated DNA.
Prostatic Hyperplasia
DD3(PCA3) gene expression in cancer and prostatic hyperplasia.
Diagnostic and prognostic scoring system for prostate cancer using urine and plasma biomarkers.
Expression of human prostatic acid phosphatase and prostate specific antigen genes in neoplastic and benign tissues.
Prostatic Neoplasms
Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma.
Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer.
Effective small interfering RNA delivery in vitro via a new stearylated cationic peptide.
Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes.
Expression analysis and clinical utility of L-Dopa decarboxylase (DDC) in prostate cancer.
Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells.
Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling.
Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer.
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.
Novel insight into the role of GAPDH playing in tumor.
Reference gene for primary culture of prostate cancer cells.
The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy.
There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue.
Proteinuria
Can glomerular mRNAs in human type 1 diabetes be used to predict transition from normoalbuminuria to microalbuminuria?
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Psoriasis
Variation in epidermal housekeeping gene expression in different pathological states.
Pulmonary Disease, Chronic Obstructive
Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers.
Urban PM2.5 activates GAPDH and induces RBC damage in COPD patients.
Rabies
Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues.
Rectal Neoplasms
GAPDH and PUM1: Optimal Housekeeping Genes for Quantitative Polymerase Chain Reaction-Based Analysis of Cancer Stem Cells and Epithelial-Mesenchymal Transition Gene Expression in Rectal Tumors.
Relapsing Fever
A glyceraldehyde-3-phosphate dehydrogenase homolog in Borrelia burgdorferi and Borrelia hermsii.
Respiratory Distress Syndrome
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
Respiratory Tract Diseases
Quantitation of respiratory syncytial virus RNA in nasal aspirates of children by real-time RT-PCR assay.
Retinal Diseases
Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders.
Retinitis
[Activity of glyceraldehyde-3-phosphate dehydrogenase in the rabbit retina and in experimental pigmentary retinitis induced by monoiodoacetate. Histochemi-study.]
Retinitis Pigmentosa
Evaluation of splicing efficiency in lymphoblastoid cell lines from patients with splicing-factor retinitis pigmentosa.
Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.
Retinoblastoma
Endogenous CRX expression and IRBP promoter activity in retinoblastoma cells.
Sarcoma
Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase.
Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy.
Sarcoma, Avian
Urea-nuclease treatment of concentrated retrovirions preserves viral RNA and removes polymerase chain reaction-amplifiable cellular RNA and DNA.
Sarcoma, Ewing
Identification of driver genes associated with chemotherapy resistance of Ewing's sarcoma.
Schistosomiasis
Identification of proteins inducing short-lived antibody responses from excreted/secretory products of Schistosoma japonicum adult worms by immunoproteomic analysis.
Production of interleukin-10 by peripheral blood mononuclear cells from residents of a marshland area in China endemic for Schistosoma japonicum.
Structure determination and analyses of the GAPDH from the parasite Schistosoma mansoni, the first one from a platyhelminth.
The functional and immunological significance of some schistosome surface molecules.
Schistosomiasis japonica
Cloning, molecular characterization, and functional activity of Schistosoma japonicum glyceraldehyde-3-phosphate dehydrogenase, a putative vaccine candidate against schistosomiasis japonica.
Identification of proteins inducing short-lived antibody responses from excreted/secretory products of Schistosoma japonicum adult worms by immunoproteomic analysis.
Schistosomiasis mansoni
Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase.
Scoliosis
Familial or Sporadic Idiopathic Scoliosis - classification based on artificial neural network and GAPDH and ACTB transcription profile.
Seizures
Disruption of GluR2/GAPDH Complex Interaction by TAT-GluR2NT1-3-2 Peptide Protects against Neuronal Death Induced by Epilepsy.
GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.
Reference Gene Validation in the Brain Regions of Young Rats after Pentylenetetrazole-Induced Seizures.
Seminoma
Standardization strategy for quantitative PCR in human seminoma and normal testis.
Sepsis
A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation.
Glyceraldehyde-3-phosphate Dehydrogenase is an Inappropriate Housekeeping Gene for Normalising Gene Expression in Sepsis.
Severe Acute Respiratory Syndrome
Development of a quantitative assay for SARS coronavirus and correlation of GAPDH mRNA with SARS coronavirus in clinical specimens.
Shock, Septic
Identification of key genes and pathways using bioinformatics analysis in septic shock children.
[Does nitric oxide stress exist?]
Skin Diseases
Quantitative real-time RT-PCR measurement of cytokine mRNA expression in the skin of normal cats and cats with allergic skin disease.
Reference gene screening of Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans for quantitative real-time PCR studies.
Sleep Apnea, Obstructive
Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy.
Sleep Deprivation
Validation of commonly used reference genes for sleep-related gene expression studies.
Small Cell Lung Carcinoma
Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients.
Spinal Cord Injuries
Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats.
Spinocerebellar Ataxias
Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders.
Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Spondylitis, Ankylosing
MicroRNA let-7i-3p affects osteoblast differentiation in ankylosing spondylitis via targeting PDK1.
Squamous Cell Carcinoma of Head and Neck
Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas.
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Reference gene selection for head and neck squamous cell carcinoma gene expression studies.
RT-PCR amplification of RNA extracted from formalin-fixed, paraffin-embedded oral cancer sections: analysis of p53 pathway.
Starvation
A feeding protocol for delivery of agents to assess development in Varroa mites.
Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation.
Atg11 is required for initiation of glucose starvation-induced autophagy.
CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer.
Changes in glycolytic activity of Lactococcus lactis induced by low temperature.
Control of glycolysis by glyceraldehyde-3-phosphate dehydrogenase in Streptococcus cremoris and Streptococcus lactis.
Effects of prebiotic oligosaccharides consumption on the growth and expression profile of cell surface-associated proteins of a potential probiotic Lactobacillus rhamnosus FSMM15.
Embryotoxicity of the nitric oxide donor sodium nitroprusside in preimplantation bovine embryos in vitro.
Evaluation and validation of experimental condition-specific reference genes for normalization of gene expression in Asia II-I Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae).
GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis.
GAPDH, rhbC, and vapA gene expression in Rhodococcus equi cultured under different iron concentrations.
GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway.
Increased expression of GAPDH protein is not indicative of nitrosative stress or apoptosis in liver of starved rainbow trout (Oncorhynchus mykiss).
Inosine-stimulated insulin release and metabolism of inosine in isolated mouse pancreatic islets.
Metabolic changes in the African fruit beetle, Pachnoda sinuata, during starvation.
MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4.
Mucin- and carbohydrate-stimulated adhesion and subproteome changes of the probiotic bacterium Lactobacillus acidophilus NCFM.
Regulation of endothelial cell survival and death by the MAP kinase/ERK kinase kinase 3 - glyceraldehyde-3-phosphate dehydrogenase signaling axis.
Screening and evaluation of the stability of expression of reference genes in Lymantria dispar (Lepidoptera: Erebidae) using qRT-PCR.
Selection and validation of experimental condition-specific reference genes for qRT-PCR in Metopolophium dirhodum (Walker) (Hemiptera: Aphididae).
Selective induction of cell cycle regulatory genes cdk1 (p34cdc2), cyclins A/B, and the tumor suppressor gene Rb in transformed cells by okadaic acid.
Starvation and temperature upshift cause an increase in the enzymatically active cell wall-associated glyceraldehyde-3-phosphate dehydrogenase protein in yeast.
Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics.
The Candida albicans cell wall-associated glyceraldehyde-3-phosphate dehydrogenase activity increases in response to starvation and temperature upshift.
Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways.
Translation inhibition reveals interaction of 2'-deoxy and 2'-O-methyl molecular beacons with mRNA targets in living cells.
Stomach Neoplasms
Comparative study of gastric cancer and chronic gastritis via network analysis.
Differential regulation of LRRC37A2 in gastric cancer by DNA methylation.
Identification of novel biomarkers, MUC5AC, MUC1, KRT7, GAPDH, CD44 for gastric cancer.
MYC quantitation in cell-free plasma DNA by real-time PCR for gastric cancer diagnosis.
Novel insight into the role of GAPDH playing in tumor.
Optimization of reference genes for normalization of the quantitative polymerase chain reaction in tissue samples of gastric cancer.
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNF?-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction.
Streptococcal Infections
Regulation of the phosphorylation of human pharyngeal cell proteins by group A streptococcal surface dehydrogenase: signal transduction between streptococci and pharyngeal cells.
Stroke
Increased cerebral expressions of MMPs, CLDN5, OCLN, ZO1 and AQPs are associated with brain edema following fatal heat stroke.
Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke.
Synovitis
Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204.
Synucleinopathies
?-Synuclein Overexpression in SH-SY5Y Human Neuroblastoma Cells Leads to the Accumulation of Thioflavin S-positive Aggregates and Impairment of Glycolysis.
Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme.
Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in ?-synuclein aggregation.
Tauopathies
Identification of non-Alzheimer's disease tauopathies-related proteins by proteomic analysis.
Tendinopathy
Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies.
Teratocarcinoma
In vitro anticancer activity of ethanol extract of Adhatoda vasica Nees on human ovarian cancer cell lines.
Testicular Neoplasms
Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells.
Thrombosis
Variations in platelet protein associated with arterial thrombosis.
Thymoma
In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development.
PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy.
Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy.
Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA levels in thymoma.
Thyroid Neoplasms
Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker.
Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells.
Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy.
Toxoplasmosis
Identification of antigenic proteins of Toxoplasma gondii RH strain recognized by human immunoglobulin G using immunoproteomics.
Triple Negative Breast Neoplasms
Thioridazine hydrochloride: an antipsychotic agent that inhibits tumor growth and lung metastasis in triple-negative breast cancer via inducing G0/G1 arrest and apoptosis.
Trypanosomiasis, African
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
Genetic validation of aldolase and glyceraldehyde-3-phosphate dehydrogenase as drug targets in Trypanosoma brucei.
Tuberculosis
Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection.
Discovery of new targeting agents against GAPDH receptor for antituberculosis drug delivery.
Expression of glyceraldehyde-3-phosphate dehydrogenase from M. tuberculosis in E. coli. Purification and characteristics of the untagged recombinant enzyme.
Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy.
Inhibitors of Glyceraldehyde 3-Phosphate Dehydrogenase and Unexpected Effects of Its Reduced Activity.
Kinetic and mechanistic characterization of the glyceraldehyde 3-phosphate dehydrogenase from Mycobacterium tuberculosis.
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1.
Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin.
Mycobacterium tuberculosis glyceraldehyde-3-phosphate dehydrogenase plays a dual role-As an adhesin and as a receptor for plasmin(ogen).
Repurposing ethyl bromopyruvate as a broad-spectrum antibacterial.
Sequence and characterization of the glyceraldehyde-3-phosphate dehydrogenase of Mycobacterium avium: correlation with an epidermal growth factor binding protein.
Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block.
Ureteral Obstruction
28S-ribosomal RNA is superior to glyceraldehyde-3-phosphate dehydrogenase as a RNA reference gene in p53-deficient mice with unilateral ureteral obstruction.
Unilateral ureteral obstruction induces renal tubular cell production of tumor necrosis factor-alpha independent of inflammatory cell infiltration.
Urinary Bladder Neoplasms
Clinical significance of thymidylate synthase expression in bladder cancer.
Expression of vascular endothelial growth factor isoforms and platelet-derived endothelial cell growth factor in bladder cancer.
Novel insight into the role of GAPDH playing in tumor.
Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer.
Uterine Cervical Neoplasms
Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines.
Expression of RAR beta2 gene by real-time RT-PCR: Differential expression in normal subjects compared to cervical cancer patients normalised against GAPDH as a housekeeping gene.
IGF1R gene expression as a predictive marker of response to ionizing radiation for patients with locally advanced HPV16-positive cervical cancer.
Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers.
Vaccinia
Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes.
Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro.
Vesicular Stomatitis
A GAPDH mutant defective in Src-dependent tyrosine phosphorylation impedes Rab2-mediated events.
Vibrio Infections
Characterization of OmpK, GAPDH and their fusion OmpK-GAPDH derived from Vibrio harveyi outer membrane proteins: their immunoprotective ability against vibriosis in large yellow croaker (Pseudosciaena crocea).
Pleurocidin Peptide Enhances Grouper Anti-Vibrio harveyi Immunity Elicited by Poly(lactide-co-glycolide)-Encapsulated Recombinant Glyceraldehyde-3-phosphate Dehydrogenase.
Viremia
CD4+CD25+ regulatory T cells are infected and activated during acute FIV infection.
Virus Diseases
18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells.
Assessment of reference gene stability influenced by extremely divergent disease symptoms in Solanum lycopersicum L.
Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues.
Differential modulations of two glyceraldehyde 3-phosphate dehydrogenase mRNAs in response to bacterial and viral challenges in a marine teleost Oplegnathus fasciatus (Perciformes).
Endogenous gene selection for relative quantification PCR and IL6 transcript levels in the PBMC's of severe and non-severe dengue cases.
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Host cell proteins interacting with the 3' end of TGEV coronavirus genome influence virus replication.
Interferon-stimulated gene products as regulators of central carbon metabolism.
Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes.
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells.
Real time PCR for monitoring regulation of host gene expression in herpes simplex virus type 1-infected human diploid cells.
Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus.
Selection and validation of candidate reference genes for quantitative real-time PCR studies in the shrimp Penaeus vannamei under viral infection.
Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus.
Using host 28S ribosomal RNA as a housekeeping gene for quantitative real-time reverse transcription-PCR (qRT-PCR) in virus-infected animal cells.
Whooping Cough
Multiplex real-time PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis.
Wilms Tumor
Glypican-3 mRNA expression level in Wilms tumor: correlation with histological type, stage, and outcome.