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Information on EC 1.2.1.58 - phenylglyoxylate dehydrogenase (acylating)

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IUBMB Comments
Requires thiamine diphosphate as cofactor. The enzyme from the denitrifying bacterium Azoarcus evansii is specific for phenylglyoxylate. 2-Oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate. Also reduces viologen dyes. Contains iron-sulfur centres and FAD.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
phenylglyoxylate:acceptor oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phenylglyoxylate + NAD+ + CoA = benzoyl-S-CoA + CO2 + NADH + H+
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PATHWAY SOURCE
PATHWAYS
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