Reference on EC 1.2.1.5 - aldehyde dehydrogenase [NAD(P)+] and Organism(s) Homo sapiens and UniProt Accession P47895
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Izaguirre, G.; Pietruszko, R.; Cho, S.; MacKerell, A.D., Jr.
Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs
J. Biomol. Struct. Dyn.
19
429-447
2001
Homo sapiens
King, G.; Holmes, R.S.
Human corneal aldehyde dehydrogenase: purification, kinetic characterisation and phenotypic variation
Biochem. Mol. Biol. Int.
31
49-63
1993
Homo sapiens
Sreerama, L.; Sladek, N.E.
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance
Biochem. Pharmacol.
45
2487-2505
1993
Homo sapiens
Glatt, H.; Rost, K.; Frank, H.; Seidel, A.; Kollock, R.
Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH2 and ALDH3A1
Arch. Biochem. Biophys.
477
196-205
2008
Homo sapiens (P30838)
Ho, K.K.; Mukhopadhyay, A.; Li, Y.F.; Mukhopadhyay, S.; Weiner, H.
A point mutation produced a class 3 aldehyde dehydrogenase with increased protective ability against the killing effect of cyclophosphamide
Biochem. Pharmacol.
76
690-696
2008
Homo sapiens (P30838), Homo sapiens
Quash, G.; Fournet, G.; Courvoisier, C.; Martinez, R.M.; Chantepie, J.; Paret, M.J.; Pharaboz, J.; Joly-Pharaboz, M.O.; Gore, J.; Andre, J.; Reichert, U.
Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture
Eur. J. Med. Chem.
43
906-916
2008
Homo sapiens (P30838), Homo sapiens
Marchitti, S.A.; Deitrich, R.A.; Vasiliou, V.
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase
Pharmacol. Rev.
59
125-150
2007
Homo sapiens (P30838), Homo sapiens (P43353), Homo sapiens (P47895)
Marchitti, S.A.; Brocker, C.; Stagos, D.; Vasiliou, V.
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
Expert. Opin. Drug Metab. Toxicol.
4
697-720
2008
Homo sapiens
Koenig, U.; Amatschek, S.; Mildner, M.; Eckhart, L.; Tschachler, E.
Aldehyde dehydrogenase 1A3 is transcriptionally activated by all-trans-retinoic acid in human epidermal keratinocytes
Biochem. Biophys. Res. Commun.
400
207-211
2010
Homo sapiens (P47895)
Gonzalez-Segura, L.; Ho, K.K.; Perez-Miller, S.; Weiner, H.; Hurley, T.D.
Catalytic contribution of threonine 244 in human ALDH2
Chem. Biol. Interact.
202
32-40
2013
Homo sapiens
Alam, M.F.; Laskar, A.A.; Choudhary, H.H.; Younus, H.
Human salivary aldehyde dehydrogenase: purification, kinetic characterization and effect of ethanol, hydrogen peroxide and sodium dodecyl sulfate on the activity of the enzyme
Cell Biochem. Biophys.
74
307-315
2016
Homo sapiens (P30838)
Tomita, H.; Tanaka, K.; Tanaka, T.; Hara, A.
Aldehyde dehydrogenase 1A1 in stem cells and cancer
Oncotarget
7
11018-11032
2016
Homo sapiens
Ma, Z.; Jiang, L.; Li, G.; Liang, D.; Li, L.; Liu, L.; Jiang, C.
Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
Bioorg. Chem.
101
103971
2020
Homo sapiens (P30838)
Buchman, C.D.; Hurley, T.D.
Inhibition of the aldehyde dehydrogenase 1/2 family by psoralen and coumarin derivatives
J. Med. Chem.
60
2439-2455
2017
Homo sapiens (P30838)
Wang, B.; Chen, X.; Wang, Z.; Xiong, W.; Xu, T.; Zhao, X.; Cao, Y.; Guo, Y.; Li, L.; Chen, S.; Huang, S.; Wang, X.; Fang, M.; Shen, Z.
Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic acid-dependent NAD+ reduction
Oncotarget
8
67043-67055
2017
Homo sapiens (P30838)
