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Information on EC 1.2.1.41 - glutamate-5-semialdehyde dehydrogenase and Organism(s) Mus musculus and UniProt Accession Q9Z110

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Mus musculus
UNIPROT: Q9Z110 not found.
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The taxonomic range for the selected organisms is: Mus musculus
The enzyme appears in selected viruses and cellular organisms
Synonyms
aldh18a1, pyrroline-5-carboxylate synthase, pyrroline-5-carboxylate synthetase, gamma-glutamyl phosphate reductase, aldh4, glutamic-gamma-semialdehyde dehydrogenase, glutamate semialdehyde dehydrogenase, glutamic gamma-semialdehyde dehydrogenase, pyrroline 5-carboxylate dehydrogenase, glutamate-gamma-semialdehyde dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Aldh18a1
isozyme
beta-glutamylphosphate reductase
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dehydrogenase, glutamate semialdehyde
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gamma-glutamyl phosphate reductase
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glutamate semialdehyde dehydrogenase
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Glutamate-5-semialdehyde dehydrogenase
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glutamate-gamma-semialdehyde dehydrogenase
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glutamic gamma-semialdehyde dehydrogenase
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Glutamyl-gamma-semialdehyde dehydrogenase
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GPR
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GSA dehydrogenase
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reductase, gamma-glutamyl phosphate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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SYSTEMATIC NAME
IUBMB Comments
L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)
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CAS REGISTRY NUMBER
COMMENTARY hide
54596-29-1
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetaldehyde + NAD+ + H2O
acetate + NADH + H+
show the reaction diagram
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?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
isozyme Aldh4a1 mRNA expression is highest in small intestine
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
P5CS_MOUSE
795
0
87266
Swiss-Prot
Mitochondrion (Reliability: 1)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Alnouti, Y.; Klaassen, C.D.
Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice
Toxicol. Sci.
101
51-64
2008
Mus musculus (Q9Z110)
Manually annotated by BRENDA team