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Information on EC 1.2.1.25 - 2-oxoisovalerate dehydrogenase (acylating)

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IUBMB Comments
Also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxopentanoate.
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The enzyme appears in viruses and cellular organisms
Synonyms
2-oxoisovalerate dehydrogenase, alpha-ketoisovalerate dehydrogenase, dehydrogenase, 2-oxoisovalerate (acylating), more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-methyl-2-oxobutanoate + CoA + NAD+ = 2-methylpropanoyl-CoA + CO2 + NADH
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