Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 1.2.1.20 - glutarate-semialdehyde dehydrogenase

for references in articles please use BRENDA:EC1.2.1.20

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme, characterized from multiple Pseudomonas strains, participates in L-lysine degradation. Unlike earlier claims, it prefers NADP+ to NAD+.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
glutarate semialdehyde dehydrogenase, gsa dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-oxopentanoate + NADP+ + H2O = glutarate + NADPH + H+
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-lysine degradation I, L-lysine degradation III, L-lysine degradation IV, L-lysine degradation X
Highest Expressing Human Cell Lines
Cell Line Links Gene Links