Any feedback?
No. of entries
Information on EC 1.2.1.16 - succinate-semialdehyde dehydrogenase [NAD(P)+]
for references in articles please use BRENDA:EC1.2.1.16
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree 1 Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
- 1.2.1.16
-
gamma-aminobutyric
- seizure
-
neurotransmitter
- transaminase
-
gamma-hydroxybutyric
-
4-hydroxybutyric
- aldh5a1
- epilepsy
-
shunt
- aciduria
-
subdural
- hematoma
-
gabaergic
-
ssadhd
- hypotonia
- gaba-transaminase
- gaba-t
- 4-aminobutyrate
- vigabatrin
-
neurometabolic
-
globus
-
tonic-clonic
-
pallidi
-
2.6.1.19
-
hyperintensities
-
evacuation
showSynonyms
succinic semialdehyde dehydrogenase, ssdh, succinate semialdehyde dehydrogenase, succinate-semialdehyde dehydrogenase, spssadh, gabd1, ssa dehydrogenase, cce4228 protein, cce4228, st0064, more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
BsSSADH
cce4228
cce4228 protein
dehydrogenase, succinate semialdehyde (nicotinamide adenine dinucleotide (phosphate))
-
-
-
-
gabD
GabD dehydrogenase
GabD1
gapN-2
NAD(P)+-dependent succinate semialdehyde dehydrogenase
-
NAD(P)+-dependent succinic semialdehyde dehydrogenase
NAD+/NADP+-dependent benzaldehyde dehydrogenase
SSA dehydrogenase
SSADH
SSADH-II
SSADHase
SSDH
-
-
-
-
SSO1842
ST0064
succinate semialdehyde dehydrogenase
succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))
-
-
-
-
succinate-semialdehyde dehydrogenase (NAD(P))
-
-
-
-
succinate-semialdehyde dehydrogenase (NAD(P)+)
-
-
-
-
succinic semialdehyde dehydrogenase
YneI
additional information
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+
-
-
-
-
succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+
mechanism is sequential, consistent with rapid-equilibrium ordered bi-bi system and a steady-state ordered bi-bi system
-
succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+
proposed enzymatic mechanism of cce4228 protein, overview
succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+
proposed enzymatic mechanism of cce4228 protein, overview
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
redox reaction
-
-
-
-
reduction
-
-
-
-
oxidation
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY SOURCE
PATHWAYS
KEGG
MetaCyc
4-aminobutanoate degradation III
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
succinate-semialdehyde:NAD(P)+ oxidoreductase
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
37250-88-7
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-naphthaldehyde + NAD+ + H2O
2-naphthoate + NADH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
2-naphthaldehyde + NADP+ + H2O
2-naphthoate + NADPH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
3-chlorobenzaldehyde + NAD+ + H2O
3-chlorobenzoate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
3-hydroxy-benzaldehyde + NAD+ + H2O
3-hydroxybenzoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
3-hydroxybenzaldehyde + NAD+ + H2O
3-hydroxybenzoate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
3-sulfopropanal + NAD(P)+ + H2O
3-sulfopropanoate + NAD(P)H + 2 H+
Substrates: -
Products: -
Products: -
?
4-chloro-benzaldehyde + NAD+ + H2O
4-chlorobenzoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
4-chlorobenzaldehyde + NAD+ + H2O
4-chlorobenzoate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
acetaldehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + 2 H+
-
Substrates: mandelate pathway
Products: -
Products: -
ir
beta-hydroxysuccinic semialdehyde + NADP+ + H2O
beta-hydroxysuccinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
cyclohexanal + NAD+ + H2O
cyclohexanecarboxylic acid + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
decanal + NAD+ + H2O
decanoate + NADH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
decanal + NADP+ + H2O
decanoate + NADPH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
heptanal + NAD+ + H2O
heptanoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
hexanal + NAD+ + H2O
hexanoate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
hexanal + NAD+ + H2O
hexanoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
malonic semialdehyde + NADP+ + H2O
malonate + NADPH + H+
-
Substrates: hydrolyzed at 8.7% the rate of succinate semialdehyde
Products: -
Products: -
?
octanal + NAD+ + H2O
octanoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
pentanal + NAD+ + H2O
pentanoate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
pentanal + NAD+ + H2O
pentanoate + NADH + H+
-
Substrates: good substrate
Products: -
Products: -
?
phenylacetaldehyde + NAD+ + H2O
phenylacetate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD(P)+ + H2O
succinate + NAD(P)H + 2 H+
Substrates: -
Products: -
Products: -
?
succinic semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NAD+ + H2O
2-oxoglutarate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NAD+ + H2O
2-oxoglutarate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NADP+ + H2O
2-oxoglutarate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NADP+ + H2O
2-oxoglutarate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: mandelate pathway
Products: -
Products: -
ir
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + H+
-
Substrates: weak reaction
Products: -
Products: -
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + H+
-
Substrates: weaker reaction compared to NAD+
Products: -
Products: -
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + H+
-
Substrates: weaker reaction compared to NAD+
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: NADP+ is the preferred cofactor
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: NADP+ is the preferred cofactor
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: NADP+ is the preferred cofactor
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: NADP+ is the preferred cofactor
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: NADP+ is the preferred cofactor
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
r
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: degradation of 3,4-dihydroxyphenylacetate in Arthrobacter sp.
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: degradation of 3,4-dihydroxyphenylacetate in Arthrobacter sp.
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
Substrates: involved in the degradation of gamma-aminobutyrate
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: involved in the degradation of gamma-aminobutyrate
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: implicated in 4-hydroxyphenylacetic acid and gamma-aminobutyric acid catabolism
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: implicated in 4-hydroxyphenylacetic acid and gamma-aminobutyric acid catabolism
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
ir
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: at 9% of the rate with NAD+
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: involved in the degradation of gamma-aminobutyrate
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: involved in the degradation of gamma-aminobutyrate
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: pathway for utilization of 4-aminobutyric acid as nitrogen source for Saccharomyces cerevisiae
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
succinic semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinic semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
additional information
?
-
Substrates: protein cce4228 shows similar catalytic efficiency towards succinate semialdehyde (SSA) at saturated concentration of NAD+ or NADP+
Products: -
Products: -
-
additional information
?
-
Substrates: protein cce4228 shows similar catalytic efficiency towards succinate semialdehyde (SSA) at saturated concentration of NAD+ or NADP+
Products: -
Products: -
-
additional information
?
-
-
Substrates: only the aldehyde forms and not the gem-diol forms of the specific substrate succinic semialdehyde , of selected aldehyde substrates, and of the inhibitor 3-tolualdehyde bind to the enzyme. Residue cysteine311 is crucial for their discrimination
Products: -
Products: -
?
additional information
?
-
-
Substrates: almost no activity with DL-glyceraldehyde, DL-glyceraldehyde 3-phosphate, and glycoaldehyde
Products: -
Products: -
?
additional information
?
-
-
Substrates: other aldehydes, such as formaldehyde, acetaldehyde and glutaraldehyde, are very poor substrates
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
Substrates: the enzyme is also active with D-glyceraldehyde 3-phosphate (Ga3P), cf. EC 1.2.1.90. Values obtained reflect a 3500 and 87fold higher catalytic efficiency when SSA/NADP+ or SSA/NAD+ pairs, respectively, are used instead of Ga3P/NADP+ or Ga3P/NAD+. Preference for NADP+ when SSA is the substrate
Products: -
Products: -
-
additional information
?
-
-
Substrates: no activity with 2-chlorobenzaldehyde, 3-chlorobenzaldehyde, and acetaldehyde
Products: -
Products: -
?
additional information
?
-
-
Substrates: no activity is observed with 2-chlorobenzaldehyde
Products: -
Products: -
?
additional information
?
-
-
Substrates: the 3- and 4-chloro substituents as well as the 3-hydroxy substituent are all electron withdrawing. All these compounds show a reduction in reaction velocity from that of the unsubstituted benzaldehyde
Products: -
Products: -
?
additional information
?
-
-
Substrates: almost no activity with D,L-glyceraldehyde, D,L-glyceraldehyde-3-phosphate, and D,L-glycolaldehyde
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme shows no detectable activity with hexanal or benzaldehyde
Products: -
Products: -
?
additional information
?
-
-
Substrates: the enzyme shows no detectable activity with hexanal or benzaldehyde
Products: -
Products: -
?
additional information
?
-
Substrates: neither propionaldehyde nor phthalaldehyde seves as substrate
Products: -
Products: -
?
additional information
?
-
-
Substrates: neither propionaldehyde nor phthalaldehyde seves as substrate
Products: -
Products: -
?
additional information
?
-
Substrates: neither propionaldehyde nor phthalaldehyde seves as substrate
Products: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-naphthaldehyde + NAD+ + H2O
2-naphthoate + NADH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
2-naphthaldehyde + NADP+ + H2O
2-naphthoate + NADPH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NAD+ + H2O
2-oxoglutarate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate semialdehyde + NADP+ + H2O
2-oxoglutarate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
3-sulfopropanal + NAD(P)+ + H2O
3-sulfopropanoate + NAD(P)H + 2 H+
Substrates: -
Products: -
Products: -
?
acetaldehyde + NADP+ + H2O
succinate + NADPH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + 2 H+
-
Substrates: mandelate pathway
Products: -
Products: -
ir
decanal + NAD+ + H2O
decanoate + NADH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
decanal + NADP+ + H2O
decanoate + NADPH + H+
Substrates: low dehydrogenase activity
Products: -
Products: -
?
succinate semialdehyde + NAD(P)+ + H2O
succinate + NAD(P)H + 2 H+
Substrates: -
Products: -
Products: -
?
succinic semialdehyde + NAD+ + H2O
succinate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: mandelate pathway
Products: -
Products: -
ir
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
-
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + 2 H+
Substrates: -
Products: -
Products: -
?