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Information on EC 1.18.1.6 - adrenodoxin-NADP+ reductase

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IUBMB Comments
A flavoprotein (FAD). The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component of the mitochondrial cytochrome P-450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones.
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Word Map
  • 1.18.1.6
  • dioxygenase
  • carbazole
  • 1,9a-dioxygenase
  • 25-hydroxyvitamin
  • cardo
  • rieske
  • p450scc
  • putidaredoxin
  • alpha-triol
  • rieske-type
  • 26-hydroxylation
  • beta-cholestane-3
  • ring-hydroxylating
  • novosphingobium
  • rig-i-mediated
  • meta-cleavage
  • 25-hydroxylase
  • spry
  • ariadne
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
2
reduced adrenodoxin
+
+
=
2
oxidized adrenodoxin
+
Synonyms
ferredoxin reductase, nadph-adrenodoxin reductase, nadph adrenodoxin reductase, nadph-dependent adrenodoxin reductase, adrenodoxin oxidoreductase, nadph:adrenodoxin reductase, adx reductase, adrenodoxin:nadp+ oxidoreductase, nadph:adrenodoxin oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 reduced adrenodoxin + NADP+ + H+ = 2 oxidized adrenodoxin + NADPH
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PATHWAY SOURCE
PATHWAYS
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