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Abortion, Spontaneous
Cytogenetic investigation of fetuses and infants conceived through intracytoplasmic sperm injection.
Acidosis
Buffering hypercapnic acidosis worsens acute lung injury.
Acidosis
Effect of oxidative stress and acidosis on diaphragm contractile function.
Acne Vulgaris
Oxidative stress in acne vulgaris.
Acute Kidney Injury
An evaluation of antioxidant effects on recovery from postischemic acute renal failure.
Acute Lung Injury
Lung injury and complement activation: role of neutrophils and xanthine oxidase.
Acute Lung Injury
Xanthine oxidase contributes to lung leak in rats subjected to skin burn.
Adenoma
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission.
Airway Obstruction
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Alagille Syndrome
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Albuminuria
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2.
Alopecia
Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients.
Aortic Aneurysm
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Aortic Coarctation
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Aortic Valve Insufficiency
Aortic dilatation resulting in chronic aortic regurgitation and complicated by aortic dissection in a patient with Turner's syndrome.
Apnea
Apnea stimulates the adaptive response to oxidative stress in elephant seal pups.
Apnea
Purine nucleoside phosphorylase and xanthine oxidase activities in erythrocytes and plasma from marine, semiaquatic and terrestrial mammals.
Arteriosclerosis
The treatment of hyperuricemia.
Arthritis
The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis.
Arthritis
[The effect of free radicals on the rabbit articular chondrocytes in monolayer culture]
Arthritis, Gouty
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
Asymptomatic Infections
Posttranslational ruling of xanthine oxidase activity in bovine milk by its substrates.
Atherosclerosis
Assessment of paraoxonase 1, xanthine oxidase and glutathione peroxidase activities, nitric oxide and thiol levels in women with polycystic ovary syndrome.
Atherosclerosis
Atherogenic Lipid Profile and Systolic Blood Pressure are Associated with Carotid Artery Intima-media Thickness in Children with Turner Syndrome.
Atherosclerosis
Circulating mononuclear cells nuclear factor-kappa B activity, plasma xanthine oxidase, and low grade inflammatory markers in adult patients with familial hypercholesterolaemia.
Atherosclerosis
Effects of garlic extract consumption on plasma and erythrocyte antioxidant parameters in atherosclerotic patients.
Atherosclerosis
Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence.
Atherosclerosis
Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.
Atherosclerosis
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Atherosclerosis
Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.
Bicuspid Aortic Valve Disease
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Blister
[XO karyotype state: primordial germ cells and blisters of the neck]
Bone Diseases, Metabolic
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Bone Resorption
Xanthine oxidase mediates cytokine-induced, but not hormone-induced bone resorption.
Brachydactyly
Limb anomalies in chromosomal aberrations.
Brain Edema
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Brain Edema
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.
Brain Injuries
Protective mechanism of grape seed oil on carbon tetrachloride-induced brain damage in ?-irradiated rats.
Brain Injuries
The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.
Brain Injuries
Xanthine oxidase does not contribute to apoptosis after brain hypoxia-ischemia in immature rabbits.
Brain Injuries
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Brain Ischemia
No conversion of xanthine dehydrogenase to oxidase in canine cerebral ischemia.
Brain Ischemia
X chromosome dosage and the response to cerebral ischemia.
Brain Ischemia
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Breast Neoplasms
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
Breast Neoplasms
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Carcinogenesis
Effects of aqueous green tea extract on activities of DNA turn-over enzymes in cancerous and non-cancerous human gastric and colon tissues.
Carcinogenesis
Xanthine Oxidase/Dehydrogenase Activity as a Source of Oxidative Stress in Prostate Cancer Tissue.
Carcinoma
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Carcinoma, Embryonal
De novo X-chromosome inactivation in somatic hybrid cells between the XO mouse embryonal carcinoma cell and XY rat lymphocyte.
Carcinoma, Embryonal
Requirement of mitoses for the reversal of X-inactivation in cell hybrids between murine embryonal carcinoma cells and normal female thymocytes.
Carcinoma, Embryonal
Variable X chromosome inactivation patterns in near-tetraploid murine EC x somatic cell hybrid cells differentiated in vitro.
Carcinoma, Hepatocellular
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Carcinoma, Hepatocellular
Imbalance of purine metabolism in hepatomas of different growth rates as expressed in behavior of xanthine oxidase (EC 1.2.3.2).
Carcinoma, Hepatocellular
Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture.
Carcinoma, Squamous Cell
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Cardiomyopathies
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Cardiomyopathies
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
Cardiomyopathies
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Cardiomyopathies
Xanthine Oxidase Inhibition Prevents Atrial Fibrillation in a Canine Model of Atrial Pacing-Induced left Ventricular Dysfunction.
Cardiomyopathy, Dilated
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Cardiotoxicity
Purine versus non-purine xanthine oxidase inhibitors against cyclophosphamide-induced cardiac and bone marrow toxicity in rats.
Cardiotoxicity
Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice.
Cardiovascular Diseases
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Cardiovascular Diseases
Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.
Cardiovascular Diseases
High-cholesterol diet increases xanthine oxidase and decreases nitric oxide synthase activities in erythrocytes from rats.
Cardiovascular Diseases
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Cardiovascular Diseases
Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?
Cardiovascular Diseases
Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels.
Cardiovascular Diseases
Role of Community Pharmacies for the Detection of Potentially Inappropriate Xanthine Oxidase Inhibitor Prescriptions.
Cardiovascular Diseases
The role of urate and xanthine oxidase inhibitors in cardiovascular disease.
Cardiovascular Diseases
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Cardiovascular Diseases
Xanthine oxidase-derived extracellular superoxide anions stimulate activator protein 1 activity and hypertrophy in human vascular smooth muscle via c-Jun N-terminal kinase and p38 mitogen-activated protein kinases.
Cataract
Xanthine oxidase activity in patients with age-related cataract associated with hypertension.
Cerebral Infarction
Evaluation of Antioxidant and Cerebroprotective Effect of Medicago sativa Linn. against Ischemia and Reperfusion Insult.
Chemical and Drug Induced Liver Injury
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study.
Cholera
Biphasic alterations in cardiac beta-adrenoceptor signal transduction mechanism due to oxyradicals.
Cholestasis
Serum xanthine oxidase in human liver disease.
Cholestasis
The effect of ursodeoxycholic acid on oxidative stress level and DNase activity in rat liver after bile duct ligation.
Cholestasis
The impact of hepatic xanthine oxidase and xanthine dehydrogenase activities on liver function in chronic cholestasis.
Cholestasis, Extrahepatic
Plasma superoxide radical in jaundiced patients and role of xanthine oxidase.
Chondrocalcinosis
Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
Colitis, Ulcerative
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Colonic Neoplasms
Endophytic naphthopyrone metabolites are co-inhibitors of xanthine oxidase, SW1116 cell and some microbial growths.
Color Vision Defects
Brief historical note: the concept of "gonadal dysgenesis".
Coma
Quantifying the Optical and Physical Consequences of Daily Cleaning on Conventional and Wavefront-guided Scleral Lenses.
Congenital Abnormalities
Radiological and clinical analysis of Madelung's deformity in children.
Contracture
Effect of reactive oxygen species on K+ contractures in the rat diaphragm.
Coronary Artery Disease
The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial.
Coronary Disease
Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease.
COVID-19
Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19.
Craniosynostoses
Turner-mongolism polysyndrome. Review of the first eight known cases.
Crohn Disease
Crohn's disease in Turner's syndrome with X-chromosomal mosaicism of 45 XO and 47 XXX.
Crohn Disease
Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants.
Crohn Disease
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Cryptorchidism
Seminoma in a 12-year-old male with 46 XY/45 XO karyotype.
Cysts
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Diabetes Mellitus
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Diabetes Mellitus
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2.
Diabetes Mellitus
[45, XO Turner's syndrome associated with menarche and diabetes mellitus]
Diabetes Mellitus
[Duodenal angiodysplasia and Turner's syndrome. Case report]
Diabetes Mellitus, Type 2
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Diabetes, Gestational
Oxidant status in maternal and cord plasma and placental tissue in gestational diabetes.
Diabetic Angiopathies
Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice.
Diabetic Cardiomyopathies
Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy.
Diabetic Nephropathies
NON-PURINE SELECTIVE XANTHINE OXIDASE INHIBITOR AMELIORATES GLOMERULAR ENDOTHELIAL INJURY IN InsAkita DIABETIC MICE.
Disorder of Sex Development, 46,XY
Male pseudohermaphroditism with XO chromosomal constitution on bone-marrow cells.
Disorder of Sex Development, 46,XY
Premature gonadal failure in female dogs and cats.
Disorders of Sex Development
Premature gonadal failure in female dogs and cats.
Down Syndrome
Antenatal diagnosis of coarctation of the aorta: a multicenter experience.
Down Syndrome
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Down Syndrome
Thickened nuchal fold in fetuses not at risk for aneuploidy.
Down Syndrome
[Association of trisomy 21 and gonosomal trisomy. Apropos of 2 cases]
Duodenal Ulcer
Histamine, xanthine oxidase generated oxygen-derived free radicals and Helicobacter pylori in gastroduodenal inflammation and ulceration.
Dupuytren Contracture
Free radicals and Dupuytren's contracture.
Eosinophilia
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study.
Esophageal Neoplasms
Molybdenum: an essential trace element.
Essential Hypertension
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Essential Hypertension
Different pathomechanisms of essential and obesity-associated hypertension in adolescents.
Eye Injuries
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
Fasciculation
Lipid peroxidation and changes in cytochrome c oxidase and xanthine oxidase activity in organophosphorus anticholinesterase induced myopathy.
Fragile X Syndrome
Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cells.
Gastritis
Histamine, xanthine oxidase generated oxygen-derived free radicals and Helicobacter pylori in gastroduodenal inflammation and ulceration.
Glomerulonephritis, IGA
The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.
Glucose Intolerance
Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Glucose-6-phosphate dehydrogenase deficiency in an XO individual.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell Anemia.
Glucosephosphate Dehydrogenase Deficiency
Glucose-6-phosphate dehydrogenase deficiency in an XO individual.
Glucosephosphate Dehydrogenase Deficiency
Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell Anemia.
Gonadal Dysgenesis
Anorexia nervosa and gonadal dysgenesis. Further evidence of a relationship.
Gonadal Dysgenesis
Gonadal dysgenesis in a newborn with XO karyotype.
Gonadal Dysgenesis
Intersexual phenotypes and sex chromosome complements of five South American opossums (Monodelphis domestica).
Gonadal Dysgenesis
Perinatal oocyte loss in XO mice and its implications for the aetiology of gonadal dysgenesis in XO women.
Gonadal Dysgenesis
Pregnancies following ovum donation in gonadal dysgenesis.
Gonadal Dysgenesis
The influence of age and sex on the metabolism of testosterone.
Gonadal Dysgenesis
X-chromosome inactivation may explain the difference in viability of XO humans and mice.
Gonadal Dysgenesis
[Etiological, clinical and hormonal characteristics of a group of patients with permanent hypogonadism]
Gonadal Dysgenesis
[Gonadal dysgenesis with hemaphroditism in cases with XX and XO sex chromosome constitution]
Gonadal Dysgenesis
[Gonadal dysgenesis with karyotype XO in the neonatal age. Long-term study with karyotype studies]
Gonadal Dysgenesis
[PURE GONADAL DYSGENESIS WITH XO KARYOTYPE.]
Gonadal Dysgenesis
[The syndrome of multiple malformations associated with gonadal dysgenesis (Turner syndrome) with XO chromosome formula.]
Gonadoblastoma
Coexistence of hereditary angioedema and Turner's syndrome.
Gonadoblastoma
Ultrastructure of gonadoblastoma.
Gout
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Gout
3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a potent inhibitor of xanthine oxidase: A potential therapeutic agent for treatment of hyperuricemia and gout.
Gout
Anti-Gouty Arthritis and Antihyperuricemia Effects of Sunflower (Helianthus annuus) Head Extract in Gouty and Hyperuricemia Animal Models.
Gout
Antioxidant and xanthine oxidase inhibitory properties and LC-MS/MS identification of compoundsof ethanolic extract from Mulberry leaves.
Gout
Cardiovascular Safety of Urate Lowering Therapies.
Gout
Characterization of the xanthine oxidase inhibitory activity of alk(en)yl phenols and related compounds.
Gout
Cleroda-4(18),13-dien-15,16-olide as novel xanthine oxidase inhibitors: An integrated in silico and in vitro study.
Gout
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
Gout
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors.
Gout
Drug Interaction Between Febuxostat and Thiopurine Antimetabolites: A Review of the FDA Adverse Event Reporting System and Medical Literature.
Gout
Effects of extracts from Corylopsis coreana Uyeki (Hamamelidaceae) flos on xanthine oxidase activity and hyperuricemia.
Gout
Effects of Temperature on the Composition and Xanthine Oxidase Inhibitory Activities of Caffeic Acid Roasting Products.
Gout
Evaluation of antigout activity of Phyllanthus emblica fruit extracts on potassium oxonate-induced gout rat model.
Gout
Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.
Gout
Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies.
Gout
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.
Gout
Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro.
Gout
High-performance liquid chromatography coupled with post-column dual-bioactivity assay for simultaneous screening of xanthine oxidase inhibitors and free radical scavengers from complex mixture.
Gout
Identification of a potent xanthine oxidase inhibitor from oxidation of caffeic acid.
Gout
Identification of crypto- and neochlorogenic lactones as potent xanthine oxidase inhibitors in roasted coffee beans.
Gout
Identification of the biologically active constituents of Camellia japonica leaf and anti-hyperuricemic effect in vitro and in vivo.
Gout
Improving cardiovascular and renal outcomes in gout: what should we target?
Gout
In vitro and in silico pharmaceutical activities of the methylated cyclic pentapeptide, persipeptides.
Gout
In vitro and in silico xanthine oxidase inhibitory activity of selected phytochemicals widely present in various edible plants.
Gout
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Gout
Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis).
Gout
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Gout
Isolation, characterization, and xanthine oxidase inhibitory activities of flavonoids from the leaves of Perilla frutescens.
Gout
Kinetic study on the inhibition of xanthine oxidase by extracts from two selected Algerian plants traditionally used for the treatment of inflammatory diseases.
Gout
Molecular mechanism of an adverse drug-drug interaction of allopurinol and furosemide in gout treatment.
Gout
Mori Ramulus (Chin.Ph.)-the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract.
Gout
Natural Products and Extracts as Xantine Oxidase Inhibitors - A Hope for Gout Disease?
Gout
S-allyl cysteine as potent anti-gout drug: Insight into the xanthine oxidase inhibition and anti-inflammatory activity.
Gout
Screening of Potential Xanthine Oxidase Inhibitors in Gnaphalium hypoleucum DC. by Immobilized Metal Affinity Chromatography and Ultrafiltration-Ultra Performance Liquid Chromatography-Mass Spectrometry.
Gout
Screening of xanthine oxidase inhibitors in complex mixtures using online HPLC coupled with postcolumn fluorescence-based biochemical detection.
Gout
Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase.
Gout
Standardization and xanthine oxidase inhibitory potential of Zanthoxylum armatum fruits.
Gout
Synthesis and evaluation of hydroxychalcones as multifunctional non-purine xanthine oxidase inhibitors for the treatment of hyperuricemia.
Gout
Synthesis, structure-activity relationships, and mechanistic studies of 5-arylazo-tropolone derivatives as novel xanthine oxidase (XO) inhibitors.
Gout
The inhibitory kinetics and mechanism of dietary vitamins D3 and B2 on xanthine oxidase.
Gout
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Gout
Two 6-(propan-2-yl)-4-methyl-morpholine-2,5-diones as new non-purine xanthine oxidase inhibitors and anti-inflammatory agents.
Gout
Xanthine Oxidase and Transforming Growth Factor Beta-activated Kinase 1: Potential Targets for Gout Intervention.
Gout
Xanthine oxidase inhibiting effects of noni (Morinda citrifolia) fruit juice.
Gout
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Gout
Xanthine oxidase inhibitors: patent landscape and clinical development (2015-2020).
Gout
Xanthine oxidase inhibitory activity of northeastern North American plant remedies used for gout.
Gout
Xanthine oxidase inhibitory activity of the methanolic extracts of selected Jordanian medicinal plants.
Gout
Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones.
Gout
Xanthine oxidase inhibitory peptides derived from tuna protein: virtual screening, inhibitory activity, and molecular mechanisms.
Gout
[Allopurinol and its role in the treatment of sarcopenia].
Granuloma
Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice.
Head and Neck Neoplasms
Do CO2 and oxidative stress induce cancer?: a brief study about the evaluation of PON 1, CAT, CA and XO enzyme levels on head and neck cancer patients.
Heart Diseases
Xanthine oxidase inhibitor, febuxostat ameliorates the high salt intake-induced cardiac hypertrophy and fibrosis in Dahl salt-sensitive rats.
Heart Failure
Allopurinol and global left myocardial function in heart failure patients.
Heart Failure
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Heart Failure
Allopurinol, Xanthine Oxidase, and Cardiac Ischemia.
Heart Failure
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment.
Heart Failure
Delayed treatment effects of xanthine oxidase inhibition on systolic overload-induced left ventricular hypertrophy and dysfunction.
Heart Failure
Disproportionate enhancement of myocardial contractility by the xanthine oxidase inhibitor oxypurinol in failing rat myocardium.
Heart Failure
Effect of Allopurinol on Myocardial Energy Metabolism in Chronic Heart Failure Rats After Myocardial Infarct.
Heart Failure
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
Heart Failure
Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study.
Heart Failure
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Heart Failure
Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload.
Heart Failure
The treatment of hyperuricemia.
Heart Failure
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Heart Failure
Uric acid and xanthine oxidase in heart failure - Emerging data and therapeutic implications.
Heart Failure
Xanthine oxidase inhibition improves left ventricular dysfunction in dilated cardiomyopathic hamsters.
Heart Failure
Xanthine Oxidase Inhibition Preserves Left Ventricular Systolic but not Diastolic Function in Cardiac Volume Overload.
Hemophilia B
Hemophilia B in a phenotypically normal girl with XX (ring) XO mosaicism.
Hepatitis
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Hepatitis, Chronic
Serum xanthine oxidase in human liver disease.
Hypercholesterolemia
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Hyperemia
Vascular dysfunction and oxidative stress caused by acute formaldehyde exposure in female adults.
Hyperglycemia
Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase.
Hyperglycemia
Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.
Hyperinsulinism
Effect of serum insulin on the association between hyperuricemia and incident heart failure.
Hyperlipidemias
Pivotal role of xanthine oxidase in the initiation of tubulointerstitial renal injury in rats with hyperlipidemia.
Hyperlipoproteinemias
[Study of the level of lipids in the blood serum of patients with Shereshevsky-Turner syndrome]
Hypertension
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Hypertension
Allopurinol does not Decrease Blood Pressure or Prevent the Development of Hypertension in the Doca-Salt Rat Model.
Hypertension
Aortic Dissecting Aneurysm with a Bicuspid Aortic Valve in Turner's Syndrome: Report of a Case.
Hypertension
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Hypertension
Different pathomechanisms of essential and obesity-associated hypertension in adolescents.
Hypertension
Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats.
Hypertension
Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro.
Hypertension
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Hypertension
Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Hypertension
Role of xanthine oxidase in dexamethasone-induced hypertension in rats.
Hypertension
The treatment of hyperuricemia.
Hypertension
Xanthine oxidase activation in mild gestational hypertension.
Hypertension
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Hypertension
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Hypertension
Xanthine oxidase inhibitor febuxostat reduces atrial fibrillation susceptibility by inhibition of oxidized CaMKII in Dahl salt-sensitive rats.
Hypertension
Xanthine oxidase mediates hypoxia-inducible factor-2? degradation by intermittent hypoxia.
Hypertension
[Duodenal angiodysplasia and Turner's syndrome. Case report]
Hypertension, Pulmonary
Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats.
Hypertension, Pulmonary
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia.
Hypertension, Pulmonary
Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow.
Hyperthyroidism
The Effect of Experimental Thyroid Dysfunction on Markers of Oxidative Stress in Rat Pancreas.
Hyperthyroidism
The role of allopurinol on oxidative stress in experimental hyperthyroidism.
Hypertrophy, Right Ventricular
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia.
Hypogonadism
The phytohemagglutinin response of human peripheral blood lymphocytes as a function of donor age: a re-examination using BrdU-Hoechst flow cytometry.
hypoxanthine phosphoribosyltransferase deficiency
The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Hypoxia-Ischemia, Brain
The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.
Ichthyosis
Sex-linked ichthyosis in XO gonadal dysgenesis.
Ichthyosis, X-Linked
Dosage of the Sts gene in the mouse.
Infarction, Middle Cerebral Artery
X chromosome dosage and the response to cerebral ischemia.
Infections
A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.
Infections
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Infections
Hepatic xanthine oxidase activity and purine nucleosides levels as physiological mediators to analyze a subcutaneous treatment with (PhSe)2 in mice infected by Toxoplasma gondii.
Infections
Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice.
Infections
Involvement of xanthine oxidase activity with oxidative and inflammatory renal damage in silver catfish experimentally infected with Streptococcus agalactiae: Interplay with reactive oxygen species and nitric oxide.
Infections
Pathogenesis of cytomegalovirus-associated pneumonitis in ICR mice: possible involvement of superoxide radicals.
Infections
Protective effect of n-acetylcysteine in a model of influenza infection in mice.
Infections
Role of Host Xanthine Oxidase in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli.
Infections
Role of host xanthine oxidase in infection due to enteropathogenic and Shiga-toxigenic Escherichia coli.
Infections
Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.
Infections
Superoxide radical is involved in the sclerotial differentiation of filamentous phytopathogenic fungi: identification of a fungal xanthine oxidase.
Infections
Temporal pattern changes in duodenal protein tyrosine nitration events in response to Eimeria acervulina infection in chickens.
Infections
Urine xanthine oxidase activity in urinary tract infection.
Infections
Xanthine oxidase activity affects pro-oxidative and pro-inflammatory profiles in spleen of silver catfish experimentally infected with Aeromonas caviae.
Infertility
Fertility, sex determination, and the X chromosome.
Infertility
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion.
Infertility
Haldane's rule and heterogametic female and male sterility in the mouse.
Infertility
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Infertility
Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background.
Infertility
Sterility associated with an XO karyotype in a Belgian mare.
Infertility
Sterility associated with an XO karyotype in a miniature horse mare.
Infertility
The significance of the XO syndrome in infertility of the mare.
Infertility, Male
Oxidative stress and male infertility.
Infertility, Male
Sex-ratio meiotic drive in Drosophila simulans is related to equational nondisjunction of the Y chromosome.
Inflammatory Bowel Diseases
Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients.
Influenza, Human
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Influenza, Human
Hemagglutination by influenza virus; the XO phase of influenza A virus.
Influenza, Human
Protective effect of n-acetylcysteine in a model of influenza infection in mice.
Insulin Resistance
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Insulin Resistance
Atherogenic Lipid Profile and Systolic Blood Pressure are Associated with Carotid Artery Intima-media Thickness in Children with Turner Syndrome.
Insulin Resistance
Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats.
Insulin Resistance
Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.
Insulin Resistance
Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?
Insulin Resistance
Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway.
Insulin Resistance
Weight loss, xanthine oxidase and serum urate levels: A prospective, longitudinal study of obese patients.
Insulin Resistance
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Insulin Resistance
Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice.
Intellectual Disability
Molybdenum: an essential trace element.
Intellectual Disability
Turner-mongolism polysyndrome. Review of the first eight known cases.
Joint Diseases
[The effect of free radicals on the rabbit articular chondrocytes in monolayer culture]
Keratoconus
A comparison of the visual acuity outcome between Clearkone and RGP lenses.
Keratoconus
Quantifying the Optical and Physical Consequences of Daily Cleaning on Conventional and Wavefront-guided Scleral Lenses.
Kidney Failure, Chronic
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Klinefelter Syndrome
Chromatin-negative Klinefelter's syndrome with focal megalencephaly.
Klinefelter Syndrome
Comparative cephalometric analysis in patients with X-chromosome aneuploidy.
Klinefelter Syndrome
Human molecular cytogenetics: diagnosis, prognosis, and disease management.
Klinefelter Syndrome
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Klinefelter Syndrome
XXY syndrome XY XO mosaicism and acentric chromosomal fragments in male schizophrenics.
Lens Subluxation
Molybdenum: an essential trace element.
Leukemia
Characterization of two newly established EBV-containing lymphoblastoid cell lines from patients with myeloid leukemias.
Leukemia
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chronic myelogenous leukemia presenting in the blastic phase and its association with a 45 XO Ph1 karyotype.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chronic myelogenous leukemia. Association with 45 XO Philadelphia chromosome karyotype and prolonged survival.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Males with chronic myeloid leukemia and the 45, XO, Ph1 chromosome pattern.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Juvenile chronic myelocytic leukemia associated with neurofibromatosis and 45, XO karyotype (author's transl)]
Leukemia, Myelomonocytic, Chronic
Characterization of two newly established EBV-containing lymphoblastoid cell lines from patients with myeloid leukemias.
Liver Diseases
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Liver Diseases
Salivary clearance and urinary metabolic pattern of caffeine in healthy children and in pediatric patients with hepatocellular diseases.
Liver Diseases
Serum xanthine oxidase in human liver disease.
Liver Diseases
Simultaneous liver and lung injury following gut ischemia is mediated by xanthine oxidase.
Lung Diseases
Detection of xanthine oxidase activity products by EPR and HPLC in bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease.
Lung Injury
FNLP injures endotoxin-primed rat lung by neutrophil-dependent and -independent mechanisms.
Lung Injury
Gut ischemia mediates lung injury by a xanthine oxidase-dependent neutrophil mechanism.
Lung Injury
Hyperoxia and xanthine dehydrogenase/oxidase activities in rat lung and heart.
Lung Injury
Lung injury after hepatoenteric ischemia-reperfusion: role of xanthine oxidase.
Lung Injury
PentaLyte decreases lung injury after aortic occlusion-reperfusion.
Lung Injury
Xanthine oxidase promotes neutrophil sequestration but not injury in hyperoxic lungs.
Lymphangioma, Cystic
Hygroma of the neck in XO abortuses. Report of two cases.
Lymphangioma, Cystic
The significance of cystic hygroma in fetuses.
Malaria
Levels and interactions of plasma xanthine oxidase, catalase and liver function parameters in Nigerian children with Plasmodium falciparum infection.
Malaria
Malaria inflammation by xanthine oxidase-produced reactive oxygen species.
Malaria
The impact of xanthine oxidase (XO) on hemolytic diseases.
Malaria, Cerebral
Malaria inflammation by xanthine oxidase-produced reactive oxygen species.
Metabolic Syndrome
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Metabolic Syndrome
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Metabolic Syndrome
Inhibitory effects of various solvent extracts from Rhamnus frangula leaves on some inflammatory and metabolic enzymes.
Metabolic Syndrome
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Muscular Atrophy
Inhibition of xanthine oxidase by allopurinol prevents skeletal muscle atrophy: role of p38 MAPKinase and E3 ubiquitin ligases.
Muscular Atrophy
Redox regulation of E3 ubiquitin ligases and their role in skeletal muscle atrophy.
Muscular Diseases
Lipid peroxidation and changes in cytochrome c oxidase and xanthine oxidase activity in organophosphorus anticholinesterase induced myopathy.
Myocardial Infarction
Allopurinol therapy of ischemic heart disease with infarct extension.
Myocardial Infarction
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
Myocardial Infarction
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment.
Myocardial Infarction
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
Myocardial Infarction
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Myocardial Ischemia
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?
Myocardial Ischemia
Ischemic heart diseases in Egypt: role of xanthine oxidase system and ischemia-modified albumin.
Myocardial Reperfusion Injury
Hydrogen peroxide mediates reperfusion injury in the isolated rat heart.
Myocardial Stunning
Selective effects of oxygen free radicals on excitation-contraction coupling in ventricular muscle. Implications for the mechanism of stunned myocardium.
Neoplasm Metastasis
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Neoplasms
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Neoplasms
A novel cancer therapy based on oxygen radicals.
Neoplasms
A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain.
Neoplasms
Adenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder cancer: a preliminary study.
Neoplasms
Adenosine deaminase, 5'-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in gastric juices from patients with gastric cancer, ulcer, and atrophic gastritis.
Neoplasms
Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders.
Neoplasms
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
Neoplasms
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Neoplasms
Brief historical note: the concept of "gonadal dysgenesis".
Neoplasms
Conversion of xanthine dehydrogenase to xanthine oxidase as a possible marker for hypoxia in tumours and normal tissues.
Neoplasms
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Neoplasms
Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition.
Neoplasms
Determination of oxygen derived free radicals producer (xanthine oxidase) and scavenger (paraoxonase1) enzymes and lipid parameters in different cancer patients.
Neoplasms
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Neoplasms
Effects of aqueous soybean, mistletoe and red clover extracts on activities of adenosine deaminase and xanthine oxidase enzyme.
Neoplasms
Eicosapentaenoic acid and oxypurinol in the treatment of muscle wasting in a mouse model of cancer cachexia.
Neoplasms
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.
Neoplasms
Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer.
Neoplasms
IFN-? regulates xanthine oxidase-mediated iNOS-independent oxidative stress in maneb- and paraquat-treated rat polymorphonuclear leukocytes.
Neoplasms
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia.
Neoplasms
Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12-myristate-13-acetate in NIH3T3 cells.
Neoplasms
Monosodium Urate and Tumor Necrosis Factor-? Increase Apoptosis in Human Chondrocyte Cultures.
Neoplasms
Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters.
Neoplasms
Pro-Oxidant Enzymes, Redox Balance and Oxidative Damage to Proteins, Lipids and DNA in Colorectal Cancer Tissue. Is Oxidative Stress Dependent on Tumour Budding and Inflammatory Infiltration?
Neoplasms
Reductive activation of doxorubicin by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumors.
Neoplasms
Serum level of Xanthine oxidase, Uric Acid, and NADPH oxidase1 in Stage I of Multiple Myeloma.
Neoplasms
Superoxide radical potentiates invasive capacity of rat ascites hepatoma cells in vitro.
Neoplasms
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
Neoplasms
The xanthine oxidase inhibitor oxypurinol reduces cancer cachexia-induced cardiomyopathy.
Neoplasms
Transforming growth factor-betas block cytokine induction of catalase and xanthine oxidase mRNA levels in cultured rat cardiac cells.
Neoplasms
Tumor necrosis factor-alpha alters response of lung cancer cells to oxidative stress.
Neoplasms
Tumor-targeting chemotherapy by a xanthine oxidase-polymer conjugate that generates oxygen-free radicals in tumor tissue.
Neoplasms
X-linked tumor suppressor genes act as presumed contributors in the sex chromosome- autosome crosstalk in cancers.
Neoplasms
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
Neoplasms
Xanthine oxidase released from reperfused hind limbs mediate kupffer cell activation, neutrophil sequestration, and hepatic oxidative stress in rats subjected to tourniquet shock.
Neoplasms
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Neoplasms
[Effects of psychological stress on xanthine oxidase expression, activity and related markers in adipose tissue of mice].
Nephritis
Oxidant stress in hyperlipidemia-induced renal damage.
Nephrolithiasis
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Neurofibromatoses
[Juvenile chronic myelocytic leukemia associated with neurofibromatosis and 45, XO karyotype (author's transl)]
Neurologic Manifestations
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.
Non-alcoholic Fatty Liver Disease
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Non-alcoholic Fatty Liver Disease
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Noonan Syndrome
Brief historical note: the concept of "gonadal dysgenesis".
Obesity
Body mass index is independently associated with xanthine oxidase activity in overweight/obese population.
Obesity
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Obesity
Inhibitory effects of various solvent extracts from Rhamnus frangula leaves on some inflammatory and metabolic enzymes.
Obesity
Weight Loss Mediated Reduction in Xanthine Oxidase Activity and Uric Acid Clearance in Adolescents with Severe Obesity.
Obesity
Xanthine oxidase and cardiovascular risk in obese children.
Oophoritis
Premature gonadal failure in female dogs and cats.
Osteoarthritis
In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis.
Osteomyelitis
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Otitis Media with Effusion
Protective effect of melatonin on experimental otitis media with effusion in guinea pigs.
Overweight
Xanthine oxidase activation in mild gestational hypertension.
Pancreatitis
The mechanism of conversion of xanthine dehydrogenase to xanthine oxidase in acute pancreatitis in the canine isolated pancreas preparation.
Pancreatitis
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Pancreatitis, Alcoholic
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Papilloma
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Persistent Infection
Hepatic xanthine oxidase activity and purine nucleosides levels as physiological mediators to analyze a subcutaneous treatment with (PhSe)2 in mice infected by Toxoplasma gondii.
Pituitary Neoplasms
[TURNER'S SYNDROME WITH PITUITARY ADENOMA AND XO KARYOTYPE.]
Pre-Eclampsia
Is Xanthine Oxidase, a Marker in Pre-eclampsia? A Case-Control Study.
Pre-Eclampsia
Maternal and fetal plasma adenosine deaminase, xanthine oxidase and malondialdehyde levels in pre-eclampsia.
Pre-Eclampsia
Plasma xanthine oxidase, superoxide dismutase and glutathione peroxidase activities and uric acid levels in severe and mild pre-eclampsia.
Prostatic Neoplasms
Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.
Proteinuria
Modulation of proteinuria and renal xanthine oxidase activity by dietary proteins in acute adriamycin nephrosis in rats: lack of correlation with intra- and extracellular amino acids.
Proteinuria
Potential sources of oxidative stress that induce postexercise proteinuria in rats.
Proteinuria
Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis.
Proteinuria
Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.
Pseudopseudohypoparathyroidism
Limb anomalies in chromosomal aberrations.
Pulmonary Disease, Chronic Obstructive
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Pulmonary Disease, Chronic Obstructive
Implication of xanthine oxidase in muscle oxidative stress in COPD patients.
Pulmonary Disease, Chronic Obstructive
Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways.
Pulmonary Disease, Chronic Obstructive
Xanthine oxidase is involved in exercise-induced oxidative stress in chronic obstructive pulmonary disease.
Pulmonary Edema
Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema.
Pulmonary Edema
Xanthine oxidase-derived oxygen radicals induce pulmonary edema via direct endothelial cell injury.
Pulmonary Edema
[Effect of the products released from the activated human neutrophils and endotoxin on bovine pulmonary endothelial cells]
Renal Insufficiency
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Renal Insufficiency
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
Renal Insufficiency
The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Renal Insufficiency, Chronic
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Renal Insufficiency, Chronic
Efficacy of xanthine oxidase inhibitor for chronic kidney disease patients with hyperuricemia.
Renal Insufficiency, Chronic
Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.
Reperfusion Injury
4-Amino-6-hydroxypyrazolo [3,4-d]pyrimidine (AHPP) conjugated PEG micelles: water soluble polymeric xanthine oxidase inhibitor.
Reperfusion Injury
A reappraisal of xanthine dehydrogenase and oxidase in hypoxic reperfusion injury: the role of NADH as an electron donor.
Reperfusion Injury
Allopurinol enhances the contractile response to dobutamine and exercise in dogs with pacing-induced heart failure.
Reperfusion Injury
Comparison of warm and cold ischemia of the canine small intestine.
Reperfusion Injury
Effects of the acetylene compound from Atractylodes rhizome on experimental gastric ulcers induced by active oxygen species.
Reperfusion Injury
Existence and participation of xanthine oxidase in reperfusion injury of ischemic rabbit myocardium.
Reperfusion Injury
Hyperoxia and xanthine dehydrogenase/oxidase activities in rat lung and heart.
Reperfusion Injury
Mechanisms of gastrointestinal ischemia-reperfusion injury and potential therapeutic interventions: a review and its implications in the horse.
Reperfusion Injury
PentaLyte decreases lung injury after aortic occlusion-reperfusion.
Reperfusion Injury
The hypoxanthine-xanthine oxidase axis is not involved in the initial phase of clinical transplantation-related ischemia-reperfusion injury.
Reperfusion Injury
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Reperfusion Injury
Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats.
Reperfusion Injury
Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme.
Reperfusion Injury
Xanthine oxidase formation during experimental ischemia of the equine small intestine.
Reperfusion Injury
Xanthine oxidase mediates elastase-induced injury to isolated lungs and endothelium.
Reperfusion Injury
Xanthine oxidase: its role in the no-reflow phenomenon.
Reperfusion Injury
[Role of active oxygen species and lipid peroxidation in liver injury induced by ischemia-reperfusion]
Reperfusion Injury
[The role of xanthine dehydrogenase (xanthine oxidase) in ischemia-reperfusion injury in rat kidney]
Respiratory Distress Syndrome
Acute and chronic effects of xanthine oxidase on lung thorax-compliance in guinea pigs.
Sarcoma
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Sarcopenia
Evaluation of Oxidative Stress Parameters and Antioxidant Status in Plasma and Erythrocytes of Elderly Diabetic Patients with Sarcopenia.
Seminoma
Seminoma in a 12-year-old male with 46 XY/45 XO karyotype.
Sepsis
Alterations in antioxidant status during neonatal sepsis.
Sepsis
The impact of xanthine oxidase (XO) on hemolytic diseases.
Sepsis
Xanthine oxidase activity in patients with sepsis.
Sex Chromosome Aberrations
Human blastocysts of normal and abnormal karyotypes display distinct transcriptome profiles.
Sex Chromosome Aberrations
Mental illness and sex chromosome aberration: renewed interest in light of a current survey.
Sex Chromosome Aberrations
[Mixed gonadal dysgenesis]
Situs Inversus
Genotoxic assessment of small mammals at an illegal dumpsite at the aomori-iwate prefectural boundary.
Spinal Cord Injuries
Xanthine oxidase in experimental spinal cord injury.
Staphylococcal Infections
A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.
steryl-sulfatase deficiency
Dosage of the Sts gene in the mouse.
Stomach Diseases
Myeloperoxidase, xanthine oxidase and superoxide dismutase in the gastric mucosa of helicobacter pylori positive and negative pediatric patients.
Stomach Ulcer
Upregulation of xanthine oxidase by tobacco smoke condensate in pulmonary endothelial cells.
Stroke
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
Subarachnoid Hemorrhage
Production of uric acid in cerebrospinal fluid after subarachnoid hemorrhage in dogs: investigation of the possible role of xanthine oxidase in chronic vasospasm.
Teratozoospermia
[Sperm sex chromosome analysis and preimplantation genetic diagnosis of patients with sex chromosome anomalies]
Trisomy 13 Syndrome
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Trisomy 18 Syndrome
Antenatal diagnosis of coarctation of the aorta: a multicenter experience.
Trisomy 18 Syndrome
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Turner Syndrome
Androgens, estrogens, and the ultimate height in XO gonadal dysgenesis.
Turner Syndrome
Aortic dilatation resulting in chronic aortic regurgitation and complicated by aortic dissection in a patient with Turner's syndrome.
Turner Syndrome
Blood typing invalidates alleged evidence of fertility of XO mare.
Turner Syndrome
Brief historical note: the concept of "gonadal dysgenesis".
Turner Syndrome
Characteristic cardiovascular anomalies of XO Turner syndrome, XX and XY phenotype and XO-XX Turner mosaic.
Turner Syndrome
Comparative cephalometric analysis in patients with X-chromosome aneuploidy.
Turner Syndrome
Crohn's disease in Turner's syndrome with X-chromosomal mosaicism of 45 XO and 47 XXX.
Turner Syndrome
Cytogenetic and molecular findings in patients with Turner's syndrome stigmata.
Turner Syndrome
Defects in the first wave of folliculogenesis in mouse XO ovaries.
Turner Syndrome
Detection of chromosomal abnormalities in the dysmorphic fetus using fluorescence in situ hybridization: evaluation for monosomy X genotype.
Turner Syndrome
Does growth hormone treatment of patients with Turner's syndrome cause an abnormal body shape?
Turner Syndrome
Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome.
Turner Syndrome
Embryonal carcinoma arising in Turner's syndrome.
Turner Syndrome
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Turner Syndrome
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion.
Turner Syndrome
Genotype, phenotype, and karyotype correlation in the XO mouse model of Turner Syndrome.
Turner Syndrome
Growth deficiency dysmorphic syndromes.
Turner Syndrome
Growth of Argentinian girls with Turner syndrome.
Turner Syndrome
Hyperandrogenism in a girl with Turner syndrome: A case report.
Turner Syndrome
Hypertensive Cerebral Hemorrhage in a Patient with Turner Syndrome Caused by Deletion in the Short Arm of the X Chromosome.
Turner Syndrome
Hypoplastic left heart syndrome with premature closure of foramen ovale: report of an unusual type of totally anomalous pulmonary venous return.
Turner Syndrome
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Turner Syndrome
Influence of oestrogen in high and low doses on plasma steroid concentrations in girls with tall stature and Turner syndrome.
Turner Syndrome
Letter: Asynchronous growth of scalp hair in XO Turner syndrome.
Turner Syndrome
Molecular detection of XO - Turner syndrome.
Turner Syndrome
Mosaicism in Turner's syndrome reflects the lethality of XO.
Turner Syndrome
No evidence for chromosomal mosaicism in multiple tissues of 10 patients with 45, XO Turner syndrome.
Turner Syndrome
Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background.
Turner Syndrome
Prepubertal periodontitis: a genetic analysis.
Turner Syndrome
Radioimmunoassay of progesterone in saliva.
Turner Syndrome
Radiological and clinical analysis of Madelung's deformity in children.
Turner Syndrome
Sex differences in brain expression of X- and Y-linked genes.
Turner Syndrome
Sex-linked ichthyosis in XO gonadal dysgenesis.
Turner Syndrome
Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain.
Turner Syndrome
Source of single X in XO Turner syndrome: a comment.
Turner Syndrome
Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cells.
Turner Syndrome
The D triisomy syndrome and XO gonadal dysgenesis in two sisters.
Turner Syndrome
The mouse as a model of fundamental concepts related to Turner syndrome.
Turner Syndrome
The position of the external ear in Turner's syndrome.
Turner Syndrome
Three novel mutations causing complete T(4)-binding globulin deficiency.
Turner Syndrome
Toxicity and outcome of intensive chemotherapy for acute lymphoblastic leukemia complicated with Turner's syndrome.
Turner Syndrome
Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome.
Turner Syndrome
Tunnel subaortic stenosis in XO Turner's syndrome.
Turner Syndrome
Turner's syndrome and carbohydrate metabolism. II. Parotid salivary insulin concentration in normal subjects and in patients with gonadal dysgenesis.
Turner Syndrome
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Turner Syndrome
Typical Turner's syndrome with 45 XO karyotype and normal menstruation. Cytogenetic and histological findings.
Turner Syndrome
Virilization in Turner syndrome.
Turner Syndrome
X-chromosome inactivation may explain the difference in viability of XO humans and mice.
Turner Syndrome
X-chromosome monosomy in the myelin-deficient rat mutant.
Turner Syndrome
[45, XO Turner's syndrome associated with menarche and diabetes mellitus]
Turner Syndrome
[A case of 45 XO Turner's syndrome. Cytohormonal interpretation of the vaginal smear in the test of ovarian stimulation with chorionic gonadotropin]
Turner Syndrome
[Chronic type A aortic dissection associated with Turner syndrome; report of a case].
Turner Syndrome
[Clinical difference between XO Turner's syndrome and 45,X-46,XX mosaicism]
Turner Syndrome
[COMMENTS ON THE XO TYPE OF TURNER'S SYNDROME.]
Turner Syndrome
[DISCUSSION OF THE PATERNAL ORIGIN OF THE X CHROMOSOME FROM A TURNER SYNDROME, XO, PROTANOPE AND XG (A-).]
Turner Syndrome
[Discussion of the paternal origin of the X of a protanopic and Xg(a--) XO Turner syndrome. New numerical estimation]
Turner Syndrome
[Echographic diagnosis of cystic hygroma. Apropos of a case]
Turner Syndrome
[Effects of weakly androgenic anabolic steroids on growth in Turner's syndrome]
Turner Syndrome
[FAMILIAL TURNER'S SYNDROME. STUDY OF 2 FAMILIES WITH XO AND XX KARYOTYPES.]
Turner Syndrome
[Feedback--regulation mechanisms using a multiple graded mestranol-norethisterone sequential preparation in XO Turner's syndrome]
Turner Syndrome
[Height in Turner's syndrome: correlation with parents' height]
Turner Syndrome
[Hygroma colli in the ultrasound image as an early indication of fetal Ullrich-Turner syndrome]
Turner Syndrome
[Significance of dermatoglyphics and palmar furrows for genetic and clinical problem formation in gynecology and obstetrics]
Turner Syndrome
[Stimulation test of the adenohypophysis with arginine, gonadotropin-releasing hormone (GRH), and thyrotropin-releasing hormone (TRH) in 45, XO patients with Turner's syndrome (author's transl)]
Turner Syndrome
[Turner's syndrome with karyotype XO associated with the Debré-Fibiger syndrome]
Turner Syndrome
[TURNER'S SYNDROME WITH PITUITARY ADENOMA AND XO KARYOTYPE.]
Turner Syndrome
[XO type of Turner's syndrome associated with coarctation of aorta---case report (author's transl)]
Turner Syndrome
[XY, XO, XX mosaicism with Turner's syndrome]
Urinary Bladder Neoplasms
Adenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder cancer: a preliminary study.
Urinary Bladder Neoplasms
Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients.
Urinary Tract Infections
Urine xanthine oxidase activity in urinary tract infection.
Urogenital Abnormalities
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Vascular Diseases
Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease.
Vascular Ring
Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.
Vascular Ring
Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings.
Vascular System Injuries
Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta.
Vascular System Injuries
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Vasospasm, Intracranial
Production of uric acid in cerebrospinal fluid after subarachnoid hemorrhage in dogs: investigation of the possible role of xanthine oxidase in chronic vasospasm.
Virus Diseases
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Virus Diseases
Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19.
Vitiligo
Oxidant-antioxidant enzymes and lipid peroxidation in generalized vitiligo.
Vitiligo
Presence of epidermal allantoin further supports oxidative stress in vitiligo.
Whooping Cough
Biphasic alterations in cardiac beta-adrenoceptor signal transduction mechanism due to oxyradicals.
xanthine oxidase deficiency
Molybdenum: an essential trace element.
XYY Karyotype
Detection of sex chromosome aneuploidies using quantitative fluorescent PCR in the Hungarian population.
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Krenitsky, T.A.; Spector, T.; Hall, W.W.
Xanthine oxidase from human liver: purification and characterization
Arch. Biochem. Biophys.
247
108-119
1986
Homo sapiens
brenda
Radi, R.; Rubbo, H.; Bush, K.; Freeman, B.A.
Xanthine oxidase binding to glycosaminoglycans: kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes
Arch. Biochem. Biophys.
339
125-135
1997
Homo sapiens
brenda
Pritsos, C.A.
Cellular distribution, metabolism and regulation of the xanthine oxidoreductase enzyme system
Chem. Biol. Interact.
129
195-208
2000
Bos taurus, Homo sapiens
brenda
Zikakis, J.P.; Dressel, M.A.; Silver, M.R.
Bovine, caprine, and human milk xanthine oxidases: isolation, purification, and characterization
Instrum. Anal. Foods, Recent Prog. (Proc. Symp. Int. Flavor Conf. , 3rd Ed. , Charalambous, G. , Inglett, G. , eds. )
2
243-303
1983
Bos taurus, Canis lupus familiaris, Capra hircus, Cavia porcellus, Oryctolagus cuniculus, Equus asinus, Equus caballus, Erythrocebus patas, Felis catus, Ovis aries, Homo sapiens, Mus musculus, Rattus norvegicus, Erythrocebus patas Patas monkey
-
brenda
Griguer, C.E.; Oliva, C.R.; Kelley, E.E.; Giles, G.I.; Lancaster, J.R.; Gillespie, G.Y.
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells
Cancer Res.
66
2257-2263
2006
Homo sapiens
brenda
Yamaguchi, Y.; Matsumura, T.; Ichida, K.; Okamoto, K.; Nishino, T.
Human Xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate
J. Biochem.
141
513-524
2007
Homo sapiens
brenda
Kalra, S.; Paul, M.K.; Balaram, H.; Mukhopadhyay, A.K.
Application of HPLC to study the kinetics of a branched bi-enzyme system consisting of hypoxanthine-guanine phosphoribosyltransferase and xanthine oxidase - an important biochemical system to evaluate the efficiency of the anticancer drug 6-mercaptopurine
J. Chromatogr. B
850
7-14
2007
Bos taurus, Homo sapiens
brenda
Akcam, M.; Elmas, O.; Yilmaz, A.; Caglar, S.; Artan, R.; Gelen, T.; Aliciguezel, Y.
Myeloperoxidase, xanthine oxidase and superoxide dismutase in the gastric mucosa of Helicobacter pylori positive and negative pediatric patients
Mol. Cell. Biochem.
290
125-130
2006
Homo sapiens
brenda
Landmesser, U.; Spiekermann, S.; Preuss, C.; Sorrentino, S.; Fischer, D.; Manes, C.; Mueller, M.; Drexler, H.
Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease
Arterioscler. Thromb. Vasc. Biol.
27
943-948
2007
Homo sapiens
brenda
Begas, E.; Kouvaras, E.; Tsakalof, A.; Papakosta, S.; Asprodini, E.K.
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios
Biomed. Chromatogr.
21
190-200
2007
Homo sapiens
brenda
Hsieh, J.F.; Wu, S.H.; Yang, Y.L.; Choong, K.F.; Chen, S.T.
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors
Bioorg. Med. Chem.
15
3450-3456
2007
Homo sapiens
brenda
George, J.; Struthers, A.D.
The role of urate and xanthine oxidase inhibitors in cardiovascular disease
Cardiovasc. Ther.
26
59-64
2008
Homo sapiens, Rattus norvegicus
brenda
Huang, X.F.; Li, H.Q.; Shi, L.; Xue, J.Y.; Ruan, B.F.; Zhu, H.L.
Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities
Chem. Biodivers.
5
636-642
2008
Homo sapiens
brenda
Luchtemberg, M.N.; Petronilho, F.; Constantino, L.; Gelain, D.P.; Andrades, M.; Ritter, C.; Moreira, J.C.; Streck, E.L.; Dal-Pizzol, F.
Xanthine oxidase activity in patients with sepsis
Clin. Biochem.
41
1186-1190
2008
Homo sapiens
brenda
Gupta, S.; Rodrigues, L.M.; Esteves, A.P.; Oliveira-Campos, A.M.; Nascimento, M.S.; Nazareth, N.; Cidade, H.; Neves, M.P.; Fernandes, E.; Pinto, M.; Cerqueira, N.M.; Bras, N.
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors
Eur. J. Med. Chem.
43
771-780
2008
Homo sapiens
brenda
Shin, M.H.; Moon, Y.J.; Seo, J.E.; Lee, Y.; Kim, K.H.; Chung, J.H.
Reactive oxygen species produced by NADPH oxidase, xanthine oxidase, and mitochondrial electron transport system mediate heat shock-induced MMP-1 and MMP-9 expression
Free Radic. Biol. Med.
44
635-645
2008
Homo sapiens
brenda
Aranda, R.; Domenech, E.; Rus, A.D.; Real, J.T.; Sastre, J.; Vina, J.; Pallardo, F.V.
Age-related increase in xanthine oxidase activity in human plasma and rat tissues
Free Radic. Res.
41
1195-1200
2007
Homo sapiens, Rattus norvegicus
brenda
Khosravan, R.; Kukulka, M.J.; Wu, J.T.; Joseph-Ridge, N.; Vernillet, L.
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase
J. Clin. Pharmacol.
48
1014-1024
2008
Homo sapiens
brenda
Matesanz, N.; Lafuente, N.; Azcutia, V.; Martin, D.; Cuadrado, A.; Nevado, J.; Rodriguez-Manas, L.; Sanchez-Ferrer, C.F.; Peiro, C.
Xanthine oxidase-derived extracellular superoxide anions stimulate activator protein 1 activity and hypertrophy in human vascular smooth muscle via c-Jun N-terminal kinase and p38 mitogen-activated protein kinases
J. Hypertens.
25
609-618
2007
Homo sapiens
brenda
Mostefai, H.A.; Agouni, A.; Carusio, N.; Mastronardi, M.L.; Heymes, C.; Henrion, D.; Andriantsitohaina, R.; Martinez, M.C.
Phosphatidylinositol 3-kinase and xanthine oxidase regulate nitric oxide and reactive oxygen species productions by apoptotic lymphocyte microparticles in endothelial cells
J. Immunol.
180
5028-5035
2008
Homo sapiens
brenda
Kudo, M.; Moteki, T.; Sasaki, T.; Konno, Y.; Ujiie, S.; Onose, A.; Mizugaki, M.; Ishikawa, M.; Hiratsuka, M.
Functional characterization of human xanthine oxidase allelic variants
Pharmacogenet. Genomics
18
243-251
2008
Homo sapiens
brenda
Mittal, A.; Phillips, A.R.; Loveday, B.; Windsor, J.A.
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery
World J. Surg.
32
288-295
2008
Felis silvestris, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Mukoyoshi, M.; Nishimura, S.; Hoshide, S.; Umeda, S.; Kanou, M.; Taniguchi, K.; Muroga, H.
In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition
Xenobiotica
38
496-510
2008
Homo sapiens
brenda
Iswantini, D.; Darusman, L.; Hidayat, R.
Indonesian Sidaguri (Sida rhombifolia L.) as antigout and inhibition kinetics of flavonoids crude extract on the activity of xanthine oxidase
J. Biol. Sci.
9
504-508
2009
Homo sapiens
-
brenda
Naoghare, P.K.; Kwon, H.T.; Song, J.M.
On-chip assay for determining the inhibitory effects and modes of action of drugs against xanthine oxidase
J. Pharm. Biomed. Anal.
51
1-6
2010
Homo sapiens
brenda
Boumerfeg, S.; Baghiani, A.; Messaoudi, D.; Khennouf, S.; Arrar, L.
Antioxidant properties and xanthine oxidase inhibitory effects of Tamus communis L. root extracts
Phytother. Res.
23
283-288
2009
Bos taurus, Ovis aries, Homo sapiens
brenda
Dai, Y.; Cao, Y.; Zhang, Z.; Vallurupalli, S.; Mehta, J.L.
Xanthine oxidase induces foam cell formation through LOX-1 and NLRP3 activation
Cardiovasc. Drugs Ther.
31
19-27
2017
Homo sapiens
brenda
Lopez-Cruz, R.I.; Perez-Milicua, M.B.; Crocker, D.E.; Gaxiola-Robles, R.; Bernal-Vertiz, J.A.; de la Rosa, A.; Vazquez-Medina, J.P.; Zenteno-Savin, T.
Purine nucleoside phosphorylase and xanthine oxidase activities in erythrocytes and plasma from marine, semiaquatic and terrestrial mammals
Comp. Biochem. Physiol. A
171
31-35
2014
Tursiops truncatus, Lontra longicaudis annectens, Sus scrofa (F1S3Y7), Mirounga angustirostris (H9A5F8), Mirounga angustirostris, Homo sapiens (P47989), Homo sapiens
brenda
1.17.3.2 xanthine oxidase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
