Information on EC 1.16.9.1 - iron:rusticyanin reductase

for references in articles please use BRENDA:EC1.16.9.1
Word Map on EC 1.16.9.1
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The expected taxonomic range for this enzyme is: Acidithiobacillus ferrooxidans

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EC NUMBER
COMMENTARY hide
1.16.9.1
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RECOMMENDED NAME
GeneOntology No.
iron:rusticyanin reductase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Fe(II) + rusticyanin = Fe(III) + reduced rusticyanin
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Fe(II) oxidation
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SYSTEMATIC NAME
IUBMB Comments
Fe(II):rusticyanin oxidoreductase
Contains c-type heme. The enzyme in Acidithiobacillus ferrooxidans is a component of an electron transfer chain from Fe(II), comprising this enzyme, the copper protein rusticyanin, cytochrome c4, and cytochrome c oxidase (EC 1.9.3.1).
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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by overexpression of Cyc2 in Acidithiobacillus ferrooxidans Fe2+ oxidation activity and arsenic stressed cell growth is increased
physiological function
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the iron:rusticyanin oxidoreductase is the primary cellular oxidant of ferrous ions in the iron respiratory electron transport chain of Thiobacillus ferrooxidans
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Fe(II) + rusticyanin
Fe(III) + reduced rusticyanin
show the reaction diagram
Fe2+ + rusticyanin
Fe3+ + reduced rusticyanin
show the reaction diagram
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?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
49700
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calculated from amino acid sequence
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partially purified by ammonium sulfate precipitation and SP-Sephadex C-25 gel filtration
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
recombinant plasmid pTCYC2 containing cyc2 gene under the control of Ptac promoter is constructed and transferred into Acidithiobacillus ferrooxidans ATCC19859
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LINKS TO OTHER DATABASES (specific for EC-Number 1.16.9.1)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)