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Information on EC 1.16.3.2 - bacterial non-heme ferritin and Organism(s) Halobacterium salinarum and UniProt Accession Q9HMP7

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EC Tree
     1 Oxidoreductases
         1.16 Oxidizing metal ions
             1.16.3 With oxygen as acceptor
                1.16.3.2 bacterial non-heme ferritin
IUBMB Comments
Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. Thousands of mineralized iron atoms are stored within the core of the structure. The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.
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Halobacterium salinarum
UNIPROT: Q9HMP7
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Word Map
The taxonomic range for the selected organisms is: Halobacterium salinarum
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
hide(Overall reactions are displayed. Show all >>)
4
+
+
6
=
4
+
8
Synonyms
ferritin a, dna-binding protein from starved cells, ecftna, cjdps, non-heme ferritin, non-heme type bacterial ferritin, bacterial non-heme ferritin, non-heme bacterial ferritin, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
non-heme type bacterial ferritin
-
FtnA
-
-
-
-
HuHF
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
Fe(II):oxygen oxidoreductase ([FeO(OH)]core-producing)
Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. Thousands of mineralized iron atoms are stored within the core of the structure. The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Fe(II) + O2 + H2O
[FeO(OH)] + H+ + H2O2
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Fe(II) + O2 + H2O
[FeO(OH)] + H+ + H2O2
show the reaction diagram
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Fe2+
the protein exhibits a ferric iron loading of 64-120 Fe ions per mole of holoprotein
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25000
12 * 25000, SDS-PAGE
291500
gel filtration
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dodecamer
12 * 25000, SDS-PAGE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
DEAE resin column chromatography and Sephacryl S-300-HR gel filtration
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reindel, S.; Anemueller, S.; Sawaryn, A.; Matzanke, B.F.
The DpsA-homologue of the archaeon Halobacterium salinarum is a ferritin
Biochim. Biophys. Acta
1598
140-146
2002
Halobacterium salinarum (Q9HMP7), Halobacterium salinarum, Halobacterium salinarum NRC 1 (Q9HMP7)
Manually annotated by BRENDA team