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Information on EC 1.16.1.10 - ferric-chelate reductase [NAD(P)H]

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EC Tree
     1 Oxidoreductases
         1.16 Oxidizing metal ions
             1.16.1 With NAD+ or NADP+ as acceptor
                1.16.1.10 ferric-chelate reductase [NAD(P)H]
IUBMB Comments
A flavoprotein. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus is not active with uncomplexed Fe(III). cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.9, ferric-chelate reductase (NADPH).
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Word Map
  • 1.16.1.10
  • epileptic
  • encephalopathy
  • excitatory
  • hyperkinetic
  • glutamatergic
  • choreoathetosis
  • neurodevelopmental
  • synapses
  • clinicians
  • disability
  • sleep
  • neurotransmission
  • monogenic
  • fad
  • ampars
The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Reaction Schemes
2
Fe(II)-siderophore
+
+
=
2
Fe(III)-siderophore
+
Synonyms
frrs1l, af0830, fro protein, chloroplast ferric chelate oxidoreductase, ferric chelate reductase 1 like protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 Fe(II)-siderophore + NAD(P)+ + H+ = 2 Fe(III)-siderophore + NAD(P)H
show the reaction diagram
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