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Information on EC 1.16.1.10 - ferric-chelate reductase [NAD(P)H]

for references in articles please use BRENDA:EC1.16.1.10

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IUBMB Comments

A flavoprotein. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus is not active with uncomplexed Fe(III). cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.9, ferric-chelate reductase (NADPH).

The expected taxonomic range for this enzyme is: Eukaryota, Archaea
  • 1.16.1.10
  • epileptic
  • encephalopathy
  • hyperkinetic
  • choreoathetosis
  • excitatory
  • biallelic
  • neurodevelopmental
  • ampa-receptors
  • ampars
  • sleep
  • neurotransmission
  • glutamatergic
  • electrograph
  • synapses
  • dyskinesia
  • monogenic
  • electroencephalogram
  • co-assembled
  • pore-forming
Reaction Schemes
2
Fe(II)-siderophore
+
+
=
2
Fe(III)-siderophore
+

Synonyms
frrs1l, fro protein, chloroplast ferric chelate oxidoreductase, ferric chelate reductase 1 like protein, af0830, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 Fe(II)-siderophore + NAD(P)+ + H+ = 2 Fe(III)-siderophore + NAD(P)H
show the reaction diagram
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