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Information on EC 1.14.99.B5 - 2-octaprenyl-6-methoxyphenol hydroxylase and Organism(s) Escherichia coli and UniProt Accession P25534

for references in articles please use BRENDA:EC1.14.99.B5
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Escherichia coli
UNIPROT: P25534
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The taxonomic range for the selected organisms is: Escherichia coli
The expected taxonomic range for this enzyme is: Escherichia coli
Synonyms
ubiH, visB, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
PATHWAY SOURCE
PATHWAYS
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-methoxy-6-(all-trans-octaprenyl)phenol + a reduced electron acceptor + oxygen
6-all-trans-octaprenyl-2-methoxy-1,4-benzoquinol + a reduced electron acceptor + H2O
show the reaction diagram
no direct biochemical evidence for the enzymatic activity. Based on information obtained from studies with ubiquinone-deficient mutants, a pathway is proposed for ubiquinone biosynthesis in Escherichia coli. ubiH mutants accumulate small quantities of 2-octaprenyl-6-methoxyphenol and relatively large amounts of 2-octaprenylphenol
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?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
the enzyme catalyzes a reaction in the ubiquinone biosynthesis pathway
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nakahigashi, K.; Miyamoto, K.; Nishimura, K.; Inokuchi, H.
Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone
J. Bacteriol.
174
7352-7359
1992
Escherichia coli (P25534)
Manually annotated by BRENDA team