Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 1.14.99.61 - cyclooctat-9-en-7-ol 5-monooxygenase and Organism(s) Streptomyces melanosporofaciens and UniProt Accession C9K1X6

for references in articles please use BRENDA:EC1.14.99.61
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Isolated from the bacterium Streptomyces melanosporofaciens M1614-43f2. Involved in the biosynthesis of cyclooctatin.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Streptomyces melanosporofaciens
UNIPROT: C9K1X6
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
The taxonomic range for the selected organisms is: Streptomyces melanosporofaciens
The expected taxonomic range for this enzyme is: Streptomyces melanosporofaciens
Synonyms
cotb3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CotB3
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
cyclooctat-9-en-7-ol,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)
Isolated from the bacterium Streptomyces melanosporofaciens M1614-43f2. Involved in the biosynthesis of cyclooctatin.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
cyclooctat-9-en-7-ol + reduced acceptor + O2
cyclooctat-9-ene-5,7-diol + acceptor + H2O
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
cyclooctat-9-en-7-ol + reduced acceptor + O2
cyclooctat-9-ene-5,7-diol + acceptor + H2O
show the reaction diagram
the enzyme is involved in the biosynthesis of cyclooctatin
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
the enzyme is involved in the biosynthesis of cyclooctatin
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
COTB3_STRMJ
459
0
50687
Swiss-Prot
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli BL21(DE3)
overexpression of the cyclooctatin biosynthetic gene cluster in Escherichia coli
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kim, S.; Zhao, P.; Igarashi, M.; Sawa, R.; Tomita, T.; Nishiyama, M.; Kuzuyama, T.
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster affordxa0a diterpene cyclase and two P450 hydroxylases
Chem. Biol.
16
736-743
2009
Streptomyces melanosporofaciens (C9K1X6), Streptomyces melanosporofaciens MI614-43F2 (C9K1X6)
Manually annotated by BRENDA team
Grner, C.; Schrepfer, P.; Redai, V.; Wallrapp, F.; Loll, B.; Eisenreich, W.; Haslbeck, M.; Brck, T.
Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids
Microb. Cell Fact.
15
86
2016
Streptomyces melanosporofaciens (C9K1X6)
Manually annotated by BRENDA team