Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 1.14.99.54 - lytic cellulose monooxygenase (C1-hydroxylating)

for references in articles please use BRENDA:EC1.14.99.54
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This copper-containing enzyme, found in fungi and bacteria, cleaves cellulose in an oxidative manner. The cellulose fragments that are formed contain a D-glucono-1,5-lactone residue at the reducing end, which hydrolyses quickly and spontaneously to the aldonic acid. The electrons are provided in vivo by the cytochrome b domain of EC 1.1.99.18, cellobiose dehydrogenase (acceptor) . Ascorbate can serve as the electron donor in vitro.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
UNIPROT: O83009
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
lytic polysaccharide monooxygenase, cbp21, cel61a, aa9 lpmo, cel61b, lpmo9d, lpmo9c, lpmo9a, pagh61b, pagh61a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
cellulose, hydrogen-donor:oxygen oxidoreductase (D-glucosyl C1-hydroxylating)
This copper-containing enzyme, found in fungi and bacteria, cleaves cellulose in an oxidative manner. The cellulose fragments that are formed contain a D-glucono-1,5-lactone residue at the reducing end, which hydrolyses quickly and spontaneously to the aldonic acid. The electrons are provided in vivo by the cytochrome b domain of EC 1.1.99.18, cellobiose dehydrogenase (acceptor) [1]. Ascorbate can serve as the electron donor in vitro.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
O83009_SERMA
197
0
21586
TrEMBL
-
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
comparative analysis of sequences, solved structures, and homology models from AA9 and AA10 LPMO families.The two LPMO families are highly conserved, structurally they have minimal sequence similarity outside the active site residues
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Book, A.; Yennamalli, R.; Takasuka, T.; Currie, C.; Phillips, G.; Fox, B.
Evolution of substrate specificity in bacterial AA10 lytic polysaccharide monooxygenases
Biotechnol. Biofuels
7
109
2014
Neurospora crassa (Q1K8B6), Neurospora crassa (Q7SA19), Neurospora crassa DSM 1257 (Q1K8B6), Neurospora crassa DSM 1257 (Q7SA19), Serratia marcescens (O83009), Thermoascus aurantiacus (G3XAP7), Thermothielavioides terrestris (D0VWZ9), Trichoderma reesei, Trichoderma reesei QM6a, Vibrio cholerae O1 (Q9KLD5), Vibrio cholerae O1 ATCC 39315 (Q9KLD5)
Manually annotated by BRENDA team