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Information on EC 1.14.99.53 - lytic chitin monooxygenase

for references in articles please use BRENDA:EC1.14.99.53

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IUBMB Comments

The enzyme cleaves chitin in an oxidative manner, releasing fragments of chitin with an N-acetylamino-D-glucono-1,5-lactone at the reducing end. The initially formed lactone at the reducing end of the shortened chitin chain quickly hydrolyses spontaneously to the aldonic acid. In vitro ascorbate can serve as reducing agent. The enzyme contains copper at the active site.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
lpmo10, lmo2467, lytic chitin monooxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[(1->4)-N-acetyl-beta-D-glucosaminyl](m+n) + reduced acceptor + O2 = [(1->4)-N-acetyl-beta-D-glucosaminyl](m-1)-(1->4)-2-(acetylamino)-2-deoxy-D-glucono-1,5-lactone + [(1->4)-N-acetyl-beta-D-glucosaminyl]n + acceptor + H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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