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BRENDA support

Information on EC 1.14.20.16 - 4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol 9-dehydrogenase

for references in articles please use BRENDA:EC1.14.20.16

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IUBMB Comments

The enzyme is active in the biosynthetic pathway of paclitaxel (Taxol) in Taxus species (yew).

The expected taxonomic range for this enzyme is: Taxus sp.

Synonyms
T9alpha oxidase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol + 2-oxoglutarate + O2 = 4-hydroxy-4alpha,5beta-5,20-epoxytax-11-en-9-one + succinate + CO2 + H2O
show the reaction diagram
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