Information on EC 1.14.20.11 - 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase

for references in articles please use BRENDA:EC1.14.20.11
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The expected taxonomic range for this enzyme is: Fischerella ambigua

EC NUMBER
COMMENTARY hide
1.14.20.11
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RECOMMENDED NAME
GeneOntology No.
3-[(Z)-2-isocyanoethenyl]-1H-indole synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
12-epi-fischerindole biosynthesis
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12-epi-hapalindole biosynthesis
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hapalindole H biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase (decarboxylating, 3-[(Z)-2-isocyanoethenyl]-1H-indole-forming)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2
3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2
3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
show the reaction diagram
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
exprerssion in Escherichia coli
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