show all | hide all No of entries

Information on EC - acyl-lipid omega-6 desaturase (cytochrome b5)

for references in articles please use BRENDA:EC1.14.19.22
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This microsomal enzyme introduces a cis double bond in fatty acids attached to lipid molecules at a location 6 carbons away from the methyl end of the fatty acid. The distance from the carboxylic acid end of the molecule does not affect the location of the new double bond. The most common substrates are oleoyl groups attached to either the sn-1 or sn-2 position of the glycerol backbone in phosphatidylcholine. cf. EC, acyl-lipid omega-6 desaturase (ferredoxin).
Specify your search results
Select one or more organisms in this record: ?
Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
1-acyl-2-oleoyl-sn-glycero-3-phosphocholine DELTA12-desaturase, 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine DELTAl2-desaturase, 18:1-phosphatidylcholine desaturase, acyl-lipid DELTA12-desaturase, BrFAD2-1, CeFAT-2, CtFAD2-1, delta 12 fatty acid desaturase, delta-12 fatty acid desaturase 2, Delta-12 oleate desaturase, more
an oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a linoleoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
Select items on the left to see more content.