Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 1.14.18.5 - sphingolipid C4-monooxygenase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9AST3

for references in articles please use BRENDA:EC1.14.18.5
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme, which belongs to the familiy of endoplasmic reticular cytochrome b5-dependent enzymes, is involved in the biosynthesis of sphingolipids in eukaryotes. Some enzymes are bifunctional and also catalyse EC 1.14.19.17, sphingolipid 4-desaturase .
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9AST3
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
sur2p, sphingolipid c4-hydroxylase, sphingolipid hydroxylase, sphingolipid delta(4)-desaturase/c4-monooxygenase, syr2p, sphinganine c4-hydroxylase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
sphingolipid C4-hydroxylase
-
SBH1
-
-
-
-
SBH2
-
-
-
-
sphinganine C4-monooxygenase
-
-
-
-
sphingolipid C4-hydroxylase
-
-
-
-
SUR2
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -
SYSTEMATIC NAME
IUBMB Comments
dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating)
The enzyme, which belongs to the familiy of endoplasmic reticular cytochrome b5-dependent enzymes, is involved in the biosynthesis of sphingolipids in eukaryotes. Some enzymes are bifunctional and also catalyse EC 1.14.19.17, sphingolipid 4-desaturase [4].
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
sphinganine + reduced acceptor + H+ + O2
phytosphinganine + acceptor + H2O
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SBH2_ARATH
259
3
29831
Swiss-Prot
Secretory Pathway (Reliability: 1)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in a Saccharomyces cerevisiae sur2v-null mutant
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sperling, P.; Ternes, P.; Moll, H.; Franke, S.; Zaehringer, U.; Heinz, E.
Functional characterization of sphingolipid C4-hydroxylase genes from Arabidopsis thaliana
FEBS Lett.
494
90-94
2001
Arabidopsis thaliana (Q9AST3), Arabidopsis thaliana
Manually annotated by BRENDA team