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Information on EC 1.14.15.24 - beta-carotene 3-hydroxylase

for references in articles please use BRENDA:EC1.14.15.24
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EC Tree
IUBMB Comments
Requires ferredoxin and Fe(II). Also acts on other carotenoids with a beta-end group. In some species canthaxanthin is the preferred substrate.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
+
4
reduced ferredoxin [iron-sulfur] cluster
+
2
+
2
=
+
4
oxidized ferredoxin [iron-sulfur] cluster
+
2
+
2
reduced ferredoxin [iron-sulfur] cluster
+
+
=
+
2
oxidized ferredoxin [iron-sulfur] cluster
+
+
2
reduced ferredoxin [iron-sulfur] cluster
+
+
=
+
2
oxidized ferredoxin [iron-sulfur] cluster
+
Synonyms
beta-hydroxylase, beta-carotene hydroxylase, cyp175a1, crtrb1, carotenoid hydroxylase, crtr-b, cyp97a3, beta-carotene oxygenase, cyp97c1, cyp97a, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 = zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
show the reaction diagram
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beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
show the reaction diagram
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beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
show the reaction diagram
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