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Information on EC 1.14.14.53 - (R)-limonene 6-monooxygenase

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IUBMB Comments
The reaction is stereospecific with over 95% yield of (+)-trans-carveol from (R)-limonene. (S)-Limonene, the substrate for EC 1.14.14.51, (S)-limonene 6-monooxygenase, is not a substrate. Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds.
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The enzyme appears in viruses and cellular organisms
Synonyms
(+)-limonene 6-monooxygenase, (+)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating), (+)-limonene-6-hydroxylase, (R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating), EC 1.14.13.80, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-limonene + [reduced NADPH-hemoprotein reductase] + O2 = (+)-trans-carveol + [oxidized NADPH-hemoprotein reductase] + H2O
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The reaction is stereospecific with over 95% yield of (+)-trans-carveol from (R)-limonene. (S)-Limonene, the substrate for EC 1.14.13.48, (S)-limonene 6-monooxygenase, is not a substrate. Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds
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