Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

show all | hide all No of entries

Information on EC 1.14.14.40 - phenylalanine N-monooxygenase

for references in articles please use BRENDA:EC1.14.14.40
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This cytochrome P-450 (heme-thiolate) enzyme, found in plants, catalyses two successive N-hydroxylations of L-phenylalanine, a committed step in the biosynthesis of benzylglucosinolate and the cyanogenic glucosides (R)-prunasin and (R)-amygdalin. The product of the two hydroxylations, N,N-dihydroxy-L-phenylalanine, is labile and undergoes dehydration followed by decarboxylation, producing an oxime. It is still not known whether the decarboxylation is spontaneous or catalysed by the enzyme.
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
cyp79a2, cyp79d16, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-phenylalanine + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-phenylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
-
-
-
-
L-phenylalanine + [reduced NADPH-hemoprotein reductase] + O2 = N-hydroxy-L-phenylalanine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
N-hydroxy-L-phenylalanine + [reduced NADPH-hemoprotein reductase] + O2 = N,N-dihydroxy-L-phenylalanine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
N,N-dihydroxy-L-phenylalanine = (E)-phenylacetaldoxime + CO2 + H2O
show the reaction diagram
-
-
-
-
Select items on the left to see more content.