Disease on EC 1.14.14.23 - cholesterol 7alpha-monooxygenase
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Adenoma
Genetic polymorphism of cholesterol 7alpha-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.
Adenoma
Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis.
Adenoviridae Infections
Expression of human cholesterol 7alpha-hydroxylase in atherosclerosis-susceptible mice via adenovirus infection.
Adrenoleukodystrophy
Case report of dysregulation of primary bile acid synthesis in a family with X-linked adrenoleukodystrophy.
Arteriosclerosis
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.
Ascorbic Acid Deficiency
Effect of dietary ascorbic acid, cholesterol and PCB on cholesterol and bile acid metabolism in a rat mutant unable to synthesize ascorbic acid.
Atherosclerosis
Cholesterol 7alpha-hydroxylase influences the expression of hepatic apoA-I in two inbred mouse strains displaying different susceptibilities to atherosclerosis and in hepatoma cells.
Atherosclerosis
Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
Atherosclerosis
CYP7A1 promoter polymorphism -203A>C affects bile salt synthesis rate in patients after ileal resection.
Atherosclerosis
Downregulation of Cyp7a1 by Cholic Acid and Chenodeoxycholic Acid in Cyp27a1/ApoE Double Knockout Mice: Differential Cardiovascular Outcome.
Atherosclerosis
Effect of GBOT on blood lipid and blood glucose metabolism in rats with atherosclerosis.
Atherosclerosis
Effects of dipeptides having a C-terminal lysine on the cholesterol 7alpha-hydroxylase mRNA level in HepG2 cells.
Atherosclerosis
Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease.
Atherosclerosis
Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events.
Atherosclerosis
Heat shock factor-1 knockout enhances cholesterol 7?-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis.
Atherosclerosis
Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment.
Atherosclerosis
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice.
Atherosclerosis
Improved assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by the use of hydroxypropyl-beta-cyclodextrin and an NADPH-regenerating system.
Atherosclerosis
Loss of small heterodimer partner expression in the liver protects against dyslipidemia.
Atherosclerosis
Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects.
Atherosclerosis
[Effects of electroacupuncture on CYP7A1 expression in liver of rabbits with atherosclerosis].
Biliary Atresia
Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation.
Biliary Atresia
CYP7A1 expression in hepatocytes is retained with upregulated fibroblast growth factor 19 in pediatric biliary atresia.
Biliary Atresia
Intestinal synthesis and secretion of bile salts as an adaptation to developmental biliary atresia in the sea lamprey.
Biliary Fistula
Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats.
Biliary Fistula
Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas.
Biliary Fistula
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat.
Brain Death
FGF15 improves outcomes after brain dead donor liver transplantation with steatotic and non-steatotic grafts in rats.
Carcinogenesis
Association between CYP7A1 and the risk of proximal colon cancer in Japanese.
Carcinogenesis
Genetic polymorphism in cytochrome P450 7A1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Carcinogenesis
Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis.
Carcinoma, Hepatocellular
A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter.
Carcinoma, Hepatocellular
Anticholestatic effects of bezafibrate in patients with primary biliary cirrhosis treated with ursodeoxycholic acid.
Carcinoma, Hepatocellular
ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1.
Carcinoma, Hepatocellular
Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase.
Carcinoma, Hepatocellular
Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.
Carcinoma, Hepatocellular
Cholesterol 7alpha-hydroxylase influences the expression of hepatic apoA-I in two inbred mouse strains displaying different susceptibilities to atherosclerosis and in hepatoma cells.
Carcinoma, Hepatocellular
Coordinate regulation of lipogenesis, the assembly and secretion of apolipoprotein B-containing lipoproteins by sterol response element binding protein 1.
Carcinoma, Hepatocellular
Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.
Carcinoma, Hepatocellular
Enhancing effect of taurine on CYP7A1 mRNA expression in Hep G2 cells.
Carcinoma, Hepatocellular
Expression of cholesterol 7alpha-hydroxylase restores bile acid synthesis in McArdle RH7777 cells.
Carcinoma, Hepatocellular
Free fatty acids repress SHP activation and adiponectin counteracts bile acid induced liver injury in super-obese patients with NASH.
Carcinoma, Hepatocellular
Green tea catechin enhances cholesterol 7alpha-hydroxylase gene expression in HepG2 cells.
Carcinoma, Hepatocellular
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
Carcinoma, Hepatocellular
Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
Carcinoma, Hepatocellular
Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid.
Carcinoma, Hepatocellular
Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7?-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.
Carcinoma, Hepatocellular
MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1.
Carcinoma, Hepatocellular
NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF-1 and CYP7A1.
Carcinoma, Hepatocellular
One or more labile proteins regulate the stability of chimeric mRNAs containing the 3'-untranslated region of cholesterol-7alpha -hydroxylase mRNA.
Carcinoma, Hepatocellular
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha activation of CYP7A1 during food restriction and diabetes is still inhibited by small heterodimer partner.
Carcinoma, Hepatocellular
Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis.
Carcinoma, Hepatocellular
Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase.
Carcinoma, Hepatocellular
Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.
Carcinoma, Hepatocellular
Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.
Carcinoma, Hepatocellular
The atypical interaction of peroxisome proliferator-activated receptor alpha with liver X receptor alpha antagonizes the stimulatory effect of their respective ligands on the murine cholesterol 7alpha-hydroxylase gene promoter.
Carcinoma, Hepatocellular
The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII.
Carcinoma, Hepatocellular
The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
Carcinoma, Hepatocellular
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
Carcinoma, Hepatocellular
Transcriptional induction of cholesterol 7alpha-hydroxylase by dexamethasone in L35 hepatoma cells requires sulfhydryl reducing agents.
Cardiovascular Diseases
Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7?-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.
Cholelithiasis
ApoB-100, ApoE and CYP7A1 gene polymorphisms in Mexican patients with cholesterol gallstone disease.
Cholelithiasis
Association of Common Single Nucleotide Polymorphisms of Candidate Genes with Gallstone Disease: A Meta-Analysis.
Cholelithiasis
Cholelithiasis induced in the Syrian hamster: evidence for an intramucinous nucleating process and down regulation of cholesterol 7 alpha-hydroxylase (CYP7) gene by medroxyprogesterone.
Cholelithiasis
Cholesterol 7alpha-Hydrolase (CYP7A1) c.-278A>C Promoter Polymorphism in Gallstone Disease Patients.
Cholelithiasis
Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma LDL cholesterol concentration.
Cholelithiasis
CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.
Cholelithiasis
Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis.
Cholelithiasis
Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease.
Cholelithiasis
Hepatic microsomal activities of cholesterol 7 alpha-hydroxylase and 3-hydroxy-3-methylglutaryl-CoA reductase in the prairie dog. An animal model for cholesterol gallstone disease.
Cholelithiasis
Improved assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by the use of hydroxypropyl-beta-cyclodextrin and an NADPH-regenerating system.
Cholelithiasis
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.
Cholelithiasis
Role of genetic variant A-204C of cholesterol 7alpha-hydroxylase (CYP7A1) in susceptibility to gallbladder cancer.
Cholelithiasis
The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man.
Cholestasis
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.
Cholestasis
Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues.
Cholestasis
Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis.
Cholestasis
Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease.
Cholestasis
Hepatic adenine nucleotides and microsomal cholesterol 7 alpha-hydroxylase activity in the obstructed and freely draining lobes of the liver after selective bile duct obstruction.
Cholestasis
Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis.
Cholestasis
Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans.
Cholestasis
Synergistic role of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7alpha-hydroxylase in the pathogenesis of manganese-bilirubin-induced cholestasis in rats.
Cholestasis
The effects, underlying mechanism and interactions of dexamethasone exposure during pregnancy on maternal bile acid metabolism.
Cholestasis
The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17?-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats.
Cholestasis
[Effect of geniposidic acid on SHP-LRH-1 signaling pathway in cholestasis rats].
Cholestasis, Intrahepatic
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes.
Cholestasis, Intrahepatic
[Expressions of SHP and CYP7A1 in pregnant rats with intrahepatic cholestasis]
cholesterol 7alpha-monooxygenase deficiency
Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.
cholesterol 7alpha-monooxygenase deficiency
Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background impairs very-low-density lipoprotein production.
cholesterol 7alpha-monooxygenase deficiency
Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol.
cholesterol 7alpha-monooxygenase deficiency
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice.
cholesterol 7alpha-monooxygenase deficiency
Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.
cholesterol 7alpha-monooxygenase deficiency
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.
Colonic Neoplasms
Association between CYP7A1 and the risk of proximal colon cancer in Japanese.
Colonic Neoplasms
Genetic polymorphism in cytochrome P450 7A1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Colonic Neoplasms
Genetic polymorphism of cholesterol 7alpha-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.
Colorectal Neoplasms
Association between CYP7A1 and the risk of proximal colon cancer in Japanese.
Colorectal Neoplasms
Genetic polymorphism in cytochrome P450 7A1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Colorectal Neoplasms
Genetic polymorphism of cholesterol 7alpha-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.
Coronary Artery Disease
CYP7A1 gene polymorphism located in the 5' upstream region modifies the risk of coronary artery disease.
Coronary Artery Disease
Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events.
Coronary Artery Disease
Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7?-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.
Coronary Artery Disease
The relationship between CYP7A1 polymorphisms, coronary artery disease & serum lipid markers.
Diabetes Mellitus
Association between cytochrome P450 promoter polymorphisms and ischemic stroke.
Diabetes Mellitus
Correlation between the decrease of cholesterol efflux from macrophages in patients with type II diabetes mellitus and down-regulated CYP7A1 expression.
Diabetes Mellitus
How the cytochrome 7a1 (CYP7A1) and ATP-binding cassette G8 (ABCG8) genetic variants affect atorvastatin response among type 2 diabetic patients attending the University of Jordan Hospital.
Diabetes Mellitus
Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7?-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.
Diabetes Mellitus, Type 2
Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes.
Dyslipidemias
Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice.
Dyslipidemias
Loss of small heterodimer partner expression in the liver protects against dyslipidemia.
Dyslipidemias
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Dyslipidemias
Pleiotropic effects of lipid genes on plasma glucose, HbA1c and HOMA-IR levels.
Dyslipidemias
Whole-Body Prolyl Hydroxylase Domain (PHD) 3 Deficiency Increased Plasma Lipids and Hematocrit Without Impacting Plaque Size in Low-Density Lipoprotein Receptor Knockout Mice.
Dyslipidemias
[CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism].
Fatty Liver
Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase.
Fatty Liver
Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.
Fatty Liver
Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice.
Fatty Liver
Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease.
Fatty Liver
Effects of sanshoamides and capsaicinoids on plasma and liver lipid metabolism in hyperlipidemic rats.
Fatty Liver
Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Fatty Liver
Low-level expression of cholesterol 7 ?-hydroxylase is associated with the formation of goose fatty liver.
Fatty Liver
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Fatty Liver
MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1.
Fatty Liver
Osthol ameliorates fat milk-induced fatty liver in mice by regulation of hepatic sterol regulatory element-binding protein-1c/2-mediated target gene expression.
Fatty Liver
Osthole improves fat milk-induced fatty liver in rats: modulation of hepatic PPAR-alpha/gamma-mediated lipogenic gene expression.
Fatty Liver
Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats.
Fatty Liver
Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7?-hydroxylase and lipoprotein lipase.
Fatty Liver
Regulation of Cholesterol Metabolism in Liver: Link to NAFLD and Impact of n-3 PUFAs.
Fatty Liver
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice.
Fatty Liver
[CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism].
Gallbladder Neoplasms
CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.
Gallbladder Neoplasms
Role of genetic variant A-204C of cholesterol 7alpha-hydroxylase (CYP7A1) in susceptibility to gallbladder cancer.
Gallstones
Accumulation of 7 alpha-hydroxycholesterol in liver tissue of patients with cholesterol gallstones.
Gallstones
Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice.
Gallstones
Antilithiasic effect of beta-cyclodextrin in LPN hamster: comparison with cholestyramine.
Gallstones
Circulating markers for biosynthesis of cholesterol and bile acids are not depressed in asymptomatic gallstone subjects.
Gallstones
Concentration of unsulfated lithocholic acid in portal and systemic venous plasma: evidence that lithocholic acid does not down regulate the hepatic cholesterol 7 alpha-hydroxylase activity in gallstone patients.
Gallstones
CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.
Gallstones
Decreased expression of cholesterol 7alpha hydroxylase and altered bile acid metabolism in Apobec-1 -/- mice leads to increased gallstone susceptibility.
Gallstones
Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis.
Gallstones
Deoxycholic acid treatment in patients with cholesterol gallstones: failure to detect a suppression of cholesterol 7alpha-hydroxylase activity.
Gallstones
Effect of chenodeoxycholic acid and phenobarbital on the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in patients with gallstones.
Gallstones
Effect of dietary taurine on cholesterol 7 alpha-hydroxylase activity in the liver of mice fed a lithogenic diet.
Gallstones
Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
Gallstones
Hepatic cholesterol and bile acid metabolism in subjects with gallstones: comparative effects of short erm feeding of chenodeoxycholic and ursodeoxycholic acid.
Gallstones
Hepatic cholesterol and bile acid synthesis in Japanese patients with cholesterol gallstones.
Gallstones
Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterol.
Gallstones
Hepatic microsomal activities of cholesterol 7 alpha-hydroxylase and 3-hydroxy-3-methylglutaryl-CoA reductase in the prairie dog. An animal model for cholesterol gallstone disease.
Gallstones
Hypothyroidism Increases Cholesterol Gallstone Prevalence in Mice by Elevated Hydrophobicity of Primary Bile Acids.
Gallstones
Increased bile acid concentration in liver tissue with cholesterol gallstone disease.
Gallstones
Influence of bezafibrate on hepatic cholesterol metabolism in gallstone patients: reduced activity of cholesterol 7 alpha-hydroxylase.
Gallstones
Modulation of cholesterol 7 alpha-hydroxylase activity by nonspecific lipid transfer protein in human liver--possibly altered regulation of its cytosolic level in patients with gallstones.
Gallstones
On the saturation of the cholesterol 7 alpha-hydroxylase in human liver microsomes.
Gallstones
Protective Effects of Yinchenhao Decoction on Cholesterol Gallstone in Mice Fed a Lithogenic Diet by Regulating LXR, CYP7A1, CYP7B1, and HMGCR Pathways.
Gallstones
Role of genetic variant A-204C of cholesterol 7alpha-hydroxylase (CYP7A1) in susceptibility to gallbladder cancer.
Gallstones
The G protein-coupled receptor G2A: involvement in hepatic lipid metabolism and gallstone formation in mice.
Hepatitis
A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model.
Hepatoblastoma
Combining intracellular and secreted bioluminescent reporter proteins for multicolor cell-based assays.
Hepatoblastoma
Dual-color bioluminescent assay using infected HepG2 cells sheds new light on Chlamydia pneumoniae and human cytomegalovirus effects on human cholesterol 7?-hydroxylase (CYP7A1) transcription.
Hepatoblastoma
Hep G2 cells: a model for studies on regulation of human cholesterol 7alpha-hydroxylase at the molecular level.
Hepatoblastoma
The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
Hepatomegaly
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Hepatomegaly
Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.
Homozygous Familial Hypercholesterolemia
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.
Hypercholesterolemia
Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.
Hypercholesterolemia
Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase.
Hypercholesterolemia
Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues.
Hypercholesterolemia
Cholesterol and bile acid synthesis during total parenteral nutrition with and without lipid emulsion in the rat.
Hypercholesterolemia
Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
Hypercholesterolemia
Cyp7a1 is continuously increased with disrupted Fxr-mediated feedback inhibition in hypercholesterolemic TALLYHO/Jng mice.
Hypercholesterolemia
Decreased protein and gene expression of hepatic cholesterol 7a-hydroxylase associated with dilated endoplasmic reticulum in chronic hypothyroid rats.
Hypercholesterolemia
Dietary chitosan enhances hepatic CYP7A1 activity and reduces plasma and liver cholesterol concentrations in diet-induced hypercholesterolemia in rats.
Hypercholesterolemia
Differences in expression of cholesterol 7alpha-hydroxylase between PHHC and Wistar rats.
Hypercholesterolemia
Effect of Cytochrome P450 7A1 (CYP7A1) Polymorphism on Lipid Responses to Simvastatin Treatment.
Hypercholesterolemia
Effect of sitosterol on the rate-limiting enzymes in cholesterol synthesis and degradation.
Hypercholesterolemia
Effects of dipeptides having a C-terminal lysine on the cholesterol 7alpha-hydroxylase mRNA level in HepG2 cells.
Hypercholesterolemia
Effects of gender on hepatic HMG-CoA reductase, cholesterol 7alpha-hydroxylase, and LDL receptor in hereditary analbuminemia.
Hypercholesterolemia
Effects of HMG-CoA reductase inhibition on hepatic expression of key cholesterol-regulatory enzymes and receptors in nephrotic syndrome.
Hypercholesterolemia
Gemfibrozil reduces non-high-density lipoprotein cholesterol in exogenously hypercholesterolemic (ExHC) rats fed a high-cholesterol diet.
Hypercholesterolemia
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
Hypercholesterolemia
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LCAT, ACAT, LDL receptor, and SRB-1 in hereditary analbuminemia.
Hypercholesterolemia
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X.
Hypercholesterolemia
Hypocholesterolemic action of pre-germinated brown rice in hepatoma-bearing rats.
Hypercholesterolemia
Increasing hepatic cholesterol 7alpha-hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits.
Hypercholesterolemia
Inhibition of miR-27b Regulates Lipid Metabolism in Skeletal Muscle of Obese Rats During Hypoxic Exercise by Increasing PPAR? Expression.
Hypercholesterolemia
Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.
Hypercholesterolemia
Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice.
Hypercholesterolemia
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.
Hypercholesterolemia
Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.
Hypercholesterolemia
Premature weaning-induced changes of cholesterol metabolism in guinea pigs.
Hypercholesterolemia
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.
Hypercholesterolemia
Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
Hypercholesterolemia
Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid.
Hypercholesterolemia
Significance of plasma 7alpha-hydroxy-4-cholesten-3-one and 27-hydroxycholesterol concentrations as markers for hepatic bile acid synthesis in cholesterol-fed rabbits.
Hypercholesterolemia
Superiority of dietary safflower oil over olive oil in lowering serum cholesterol and increasing hepatic mRnas for the LDL receptor and cholesterol 7alpha-hydroxylase in exogenously hypercholesterolemic (exHC) rats.
Hypercholesterolemia
The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men.
Hypercholesterolemia
Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.
Hypercholesterolemia
Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease.
Hypercholesterolemia
Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia.
Hypercholesterolemia
Up-regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) in nephrotic syndrome.
Hyperglycemia
Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity.
Hyperglycemia
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Hyperhomocysteinemia
Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease.
Hyperinsulinism
NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF-1 and CYP7A1.
Hyperlipidemias
A new TCM formula FTZ lowers serum cholesterol by regulating HMG-CoA reductase and CYP7A1 in hyperlipidemic rats.
Hyperlipidemias
Antihyperlipidemic and Hepatoprotective Properties of Vitamin B6 Supplementation in Rats with High-Fat Diet-Induced Hyperlipidemia.
Hyperlipidemias
Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism.
Hyperlipidemias
Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Hyperlipidemias
Enterococcus faecium WEFA23 from infants lessens high-fat-diet-induced hyperlipidemia via cholesterol 7-alpha-hydroxylase gene by altering the composition of gut microbiota in rats.
Hyperlipidemias
Glucomannan and glucomannan plus spirulina added to pork significantly block dietary cholesterol effects on lipoproteinemia, arylesterase activity, and CYP7A1 expression in Zucker fa/fa rats.
Hyperlipidemias
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X.
Hyperlipidemias
Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype.
Hyperlipidemias
Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
Hyperlipidemias
Protective role of puerarin on lead-induced alterations of the hepatic glutathione antioxidant system and hyperlipidemia in rats.
Hyperlipidemias
Regulation of Cholesterol Metabolism in Liver: Link to NAFLD and Impact of n-3 PUFAs.
Hyperlipidemias
Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.
Hyperlipidemias
[Intervention of Huayu Qutan Recipe on liver SREBP-2 signal pathway of hyperlipidemia rats of pi deficiency syndrome].
Hyperlipoproteinemia Type II
Genes Potentially Associated with Familial Hypercholesterolemia.
Hyperlipoproteinemia Type II
No genetic linkage or molecular evidence for involvement of the PCSK9, ARH or CYP7A1 genes in the Familial Hypercholesterolemia phenotype in a sample of Danish families without pathogenic mutations in the LDL receptor and apoB genes.
Hyperlipoproteinemia Type II
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.
Hypersensitivity
The nuclear matrix protein CDP represses hepatic transcription of the human cholesterol-7alpha hydroxylase gene.
Hypertension
Biochemical and morphological characterization of spontaneously hypertensive hyperlipidaemic rats.
Hypertension
CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population.
Hypertension
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X.
Hypertension
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Hyperthyroidism
Cholesterol 7 alpha-hydroxylase activity in hypothyroidism and hyperthyroidism in humans.
Hyperthyroidism
Effect of modification of thyroid function on cholesterol 7 alpha-hydroxylation in rat liver.
Hyperthyroidism
Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice.
Hypertriglyceridemia
Common genetic variants contribute to primary hypertriglyceridemia without differences between familial combined hyperlipidemia and isolated hypertriglyceridemia.
Hypertriglyceridemia
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.
Hypertriglyceridemia
[Association between cholesterol 7alpha-hydroxylase -204A/C gene polymorphism and endogenous hypertriglyceridemia in Chinese]
Hypothyroidism
Cholesterol 7 alpha-hydroxylase activity in hypothyroidism and hyperthyroidism in humans.
Hypothyroidism
Decreased protein and gene expression of hepatic cholesterol 7a-hydroxylase associated with dilated endoplasmic reticulum in chronic hypothyroid rats.
Hypothyroidism
Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice.
Hypothyroidism
THYROID-STIMULATING HORMONE LEVELS ARE INVERSELY ASSOCIATED WITH SERUM TOTAL BILE ACID LEVELS: A CROSS-SECTIONAL STUDY.
Hypothyroidism
[CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism].
Infections
Dual-color bioluminescent assay using infected HepG2 cells sheds new light on Chlamydia pneumoniae and human cytomegalovirus effects on human cholesterol 7?-hydroxylase (CYP7A1) transcription.
Infections
Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo.
Infections
In vivo regulation of murine CYP7A1 by HNF-6: a novel mechanism for diminished CYP7A1 expression in biliary obstruction.
Infections
Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse.
Infections
Reciprocal regulation of farnesoid X receptor ? activity and hepatitis B virus replication in differentiated HepaRG cells and primary human hepatocytes.
Infections
Testosterone response of hepatic gene expression in female mice having acquired testosterone-unresponsive immunity to Plasmodium chabaudi malaria.
Insulin Resistance
Alteration of FXR phosphorylation and sumoylation in liver in the development of adult catch-up growth.
Insulin Resistance
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis.
Insulin Resistance
Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice.
Insulin Resistance
Hepatocyte Sortilin 1 knockout and treatment with a Sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice.
Insulin Resistance
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X.
Insulin Resistance
Insulin-dependent suppression of cholesterol 7?-hydroxlase is a possible link between glucose and cholesterol metabolisms.
Insulin Resistance
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Insulin Resistance
NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF-1 and CYP7A1.
Insulin Resistance
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice.
Liver Cirrhosis
Chemical profile of Swertia mussotii Franch and its potential targets against liver fibrosis revealed by cross-platform metabolomics.
Liver Cirrhosis
Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease.
Liver Cirrhosis
The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model.
Liver Cirrhosis, Biliary
Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway.
Liver Diseases
A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model.
Liver Diseases
Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients.
Liver Diseases
Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease.
Liver Diseases
Establishment of an ex Vivo Model of Nonalcoholic Fatty Liver Disease Using a Tissue-Engineered Liver.
Liver Diseases
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Liver Diseases
Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice.
Liver Diseases
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver.
Liver Diseases
Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease.
Liver Diseases
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice.
Liver Diseases
[CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism].
Liver Diseases, Alcoholic
Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice.
Liver Neoplasms
Transcriptional toxicity of the Yangtze River source water on mouse (Mus musculus) detected by cDNA microarray.
Malnutrition
Undernutrition Shapes the Gut Microbiota and Bile Acid Profile in Association with Altered Gut-Liver FXR Signaling in Weaning Pigs.
Metabolic Syndrome
NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF-1 and CYP7A1.
Metabolic Syndrome
STUDIES ON THE EXPRESSION LEVELS OF STEROL-METABOLIZING ENZYMES IN THE OBESE MODEL SHR/NDmcr-cp RATS.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver.
Multiple Sclerosis
Variants in the promoter region of CYP7A1 are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population.
Myocardial Infarction
Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease.
Neoplasms
A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice.
Neoplasms
Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting.
Neoplasms
All-trans-retinoic acid improves cholestasis in ?-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
Neoplasms
Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase.
Neoplasms
Co-administration of obeticholic acid and simvastatin protects against high-fat diet-induced non-alcoholic steatohepatitis in mice.
Neoplasms
Corn silk extract improves cholesterol metabolism in C57BL/6J mouse fed high-fat diets.
Neoplasms
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.
Neoplasms
Posttranscriptional regulation of mRNA levels in rat liver associated with deoxycholic acid feeding.
Neoplasms
Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice.
Neoplasms
The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.
Neoplasms
Tumor necrosis factor-alpha-independent downregulation of hepatic cholesterol 7alpha-hydroxylase gene in mice treated with lead nitrate.
Nephrosis
Gene expression of hepatic cholesterol 7 alpha-hydroxylase in the course of puromycin-induced nephrosis.
Nephrotic Syndrome
Studies of alteration of hepatic cholesterol metabolism in puromycin-induced nephrotic syndrome in rats.
Nephrotic Syndrome
Up-regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) in nephrotic syndrome.
Neurocutaneous Syndromes
Unique Variant of Cerebrotendinous Xanthomatosis Presenting With Eyelid Involvement Due to Heterozygous CYP7A1 and SLC10A1 Gene Mutations.
Neuromyelitis Optica
Common CYP7A1 promoter polymorphism associated with risk of neuromyelitis optica.
Neuromyelitis Optica
Variants in the promoter region of CYP7A1 are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population.
Non-alcoholic Fatty Liver Disease
A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates.
Non-alcoholic Fatty Liver Disease
Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver.
Non-alcoholic Fatty Liver Disease
Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Establishment of an ex Vivo Model of Nonalcoholic Fatty Liver Disease Using a Tissue-Engineered Liver.
Non-alcoholic Fatty Liver Disease
Integrated Analysis of Multiple Microarray Studies to Identify Novel Gene Signatures in Non-alcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Lactobacillus fermentum CQPC06 in naturally fermented pickles prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis in mice.
Non-alcoholic Fatty Liver Disease
Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver.
Non-alcoholic Fatty Liver Disease
Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice.
Non-alcoholic Fatty Liver Disease
Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
[CYP7A1 gene polymorphism and the characteristics of dyslipidemias in patients with nonalcoholic fatty liver disease concurrent with hypothyroidism].
Obesity
Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.
Obesity
Hepatic cholesterol accumulation ascribed to the activation of ileum Fxr-Fgf15 pathway inhibiting hepatic Cyp7a1 in high-fat diet-induced obesity rats.
Obesity
Hepatocyte Sortilin 1 knockout and treatment with a Sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice.
Obesity
HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X.
Obesity
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Obesity
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice.
Rectal Neoplasms
Genetic polymorphism in cytochrome P450 7A1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Renal Insufficiency
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7 alpha-hydroxylase in rats with subtotal nephrectomy.
Sarcoma, Avian
Expression of human cholesterol 7alpha-hydroxylase in atherosclerosis-susceptible mice via adenovirus infection.
Sepsis
On the Role of Illness Duration and Nutrient Restriction in Cholestatic Alterations that Occur During Critical Illness.
Sepsis
Retinoid X receptor alpha participation in dexamethasone induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver.
Smith-Lemli-Opitz Syndrome
Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7alpha-hydroxylase and 27-hydroxylase activities in rat liver.
Starvation
Serum starvation improves transient transfection efficiency in differentiating embryonic stem cells.
Starvation
Studies on the link between HMG-CoA reductase and cholesterol 7 alpha-hydroxylase in rat liver.
Tuberculosis
The CYP7A1 gene rs3808607 variant is associated with susceptibility of tuberculosis in Moroccan population.
Vitamin E Deficiency
Effects of vitamin E deficiency on the distribution of cholesterol in plasma lipoproteins and the activity of cholesterol 7 alpha-hydroxylase in rabbit liver.
Xanthomatosis
Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase.
Xanthomatosis
Unique Variant of Cerebrotendinous Xanthomatosis Presenting With Eyelid Involvement Due to Heterozygous CYP7A1 and SLC10A1 Gene Mutations.
Xanthomatosis, Cerebrotendinous
Unique Variant of Cerebrotendinous Xanthomatosis Presenting With Eyelid Involvement Due to Heterozygous CYP7A1 and SLC10A1 Gene Mutations.
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