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Information on EC 1.14.14.18 - heme oxygenase (biliverdin-producing)
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1.14.14.18 heme oxygenase (biliverdin-producing)IUBMB Comments
This mammalian enzyme participates in the degradation of heme. The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules . The third oxygen molecule provides the oxygen atom that converts the alpha-carbon to CO. The enzyme requires NAD(P)H and EC 1.6.2.4, NADPH---hemoprotein reductase. cf. EC 1.14.15.20, heme oxygenase (biliverdin-producing, ferredoxin).
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Word Map
- 1.14.14.18
- monoxide
-
cytoprotective
- endothelial
- necrosis
- dismutase
- protoporphyrin
-
erythroid
-
2-related
- tnf
- bilirubin
- artery
- malondialdehyde
- lipopolysaccharide
- catalase
- hemin
-
neuroprotective
- ischemia
- gsh
- lps
- sod
-
anti-oxidant
- mapks
- sirna
- caspase-3
- quinone
- pulmonary
-
reperfusion
-
lps-induced
- hypoxia
- cyclooxygenase-2
- cox-2
- ferritin
- erk
-
nf-e2-related
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anti-apoptotic
- cobalt
- myeloperoxidase
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ischemia-reperfusion
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nrf2-mediated
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pro-oxidant
-
kelch-like
-
nadph:quinone
-
factor-2
-
lps-stimulated
-
2-like
-
erythroid-derived
- oxygenases
-
delta-aminolevulinic
- sulforaphane
- hyperbilirubinemia
- medicine
- drug development
- analysis
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
heme oxygenase-1, heme oxygenase, hmox1, heme oxygenase 1, haem oxygenase, hsp32, heme oxygenase-2, hmox2, heme oxygenase 2, hmox1a, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
haem oxygenase
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ORP33 proteins
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oxygenase, heme (decyclizing)
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proteins, specific or class, ORP33 (oxygen-regulated protein 33,000-mol.-wt.)
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
BRENDA
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SYSTEMATIC NAME
IUBMB Comments
protoheme,NADPH-hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
This mammalian enzyme participates in the degradation of heme. The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules [4]. The third oxygen molecule provides the oxygen atom that converts the alpha-carbon to CO. The enzyme requires NAD(P)H and EC 1.6.2.4, NADPH---hemoprotein reductase. cf. EC 1.14.15.20, heme oxygenase (biliverdin-producing, ferredoxin).
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CAS REGISTRY NUMBER
COMMENTARY
9059-22-7
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
protoheme + [reduced NADPH-hemoprotein reductase] + O2
biliverdin IXbeta + biliverdin IXdelta + Fe2+ + CO + [oxidized NADPH-hemoprotein reductase] + H2O
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
(E)-2-(4-isopropylbenzylidene)hydrazinecarboximidamide
compound shows a binding affinity of 5.7 microM and an MIC50 of 52.3 microg/ml against Pseudomonas aeruginosa PAO1 and increased activity against clinical isolates of Pseudomonas aeruginosa
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Habitual
The size of a microsatellite polymorphism of the haem oxygenase 1 gene is associated with idiopathic recurrent miscarriage.
Abortion, Spontaneous
Haem oxygenases play a pivotal role in placental physiology and pathology.
Acidosis
Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells.
Acidosis
Heme Oxygenase-1 Does Not Mediate the Effects of Extracellular Acidosis on Vascular Smooth Muscle Cell Proliferation, Migration, and Susceptibility to Apoptosis.
Acidosis
Protective effect of hypercapnic acidosis in ischemia-reperfusion lung injury is attributable to upregulation of heme oxygenase-1.
Acidosis
The p38 mitogen-activated protein kinase pathway is involved in the regulation of heme oxygenase-1 by acidic extracellular pH in aortic smooth muscle cells.
Acquired Immunodeficiency Syndrome
Cellular cholesterol modifies flow-mediated gene expression.
Acquired Immunodeficiency Syndrome
Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients.
Acquired Immunodeficiency Syndrome
Host heme oxygenase-1: Friend or foe in tackling pathogens?
Acute Chest Syndrome
Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease.
Acute Coronary Syndrome
Heme Oxygenase-1 Restores Impaired GARPCD4(+)CD25(+) Regulatory T Cells from Patients with Acute Coronary Syndrome by Upregulating LAP and GARP Expression on Activated T Lymphocytes.
Acute Kidney Injury
6-Shogaol protects against ischemic acute kidney injury by modulating NF-?B and heme oxygenase-1 pathways.
Acute Kidney Injury
Activation of AMP-activated protein kinase inhibits ER stress and renal fibrosis.
Acute Kidney Injury
Acute renal hemodynamic effects of dimanganese decacarbonyl and cobalt protoporphyrin.
Acute Kidney Injury
Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-?B axis and upregulating heme oxygenase-1.
Acute Kidney Injury
Changes in 25-hydroxyvitamin D3 alpha- and 24-hydroxylase activities of kidney cells isolated from rats with either unilateral kidney damage or acute renal insufficiency.
Acute Kidney Injury
Cyclin-dependent kinase inhibitor p18INK4c is involved in protective roles of heme oxygenase-1 in cisplatin-induced acute kidney injury.
Acute Kidney Injury
Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury.
Acute Kidney Injury
Epithelial cell polarity and hypoxia influence heme oxygenase-1 expression by heme in renal epithelial cells.
Acute Kidney Injury
Fundamental role of heme oxygenase in the protection against ischemic acute renal failure.
Acute Kidney Injury
Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury.
Acute Kidney Injury
Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury.
Acute Kidney Injury
Heme oxygenase-1 induction mitigates burn-associated early acute kidney injury via the TLR4 signaling pathway.
Acute Kidney Injury
Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury.
Acute Kidney Injury
Heme oxygenase-1 protects against radiocontrast-induced acute kidney injury by regulating anti-apoptotic proteins.
Acute Kidney Injury
Heme oxygenase-2 protects against ischemic acute kidney injury: influence of age and sex.
Acute Kidney Injury
Hepatocyte growth factor prevents multiple organ injuries in endotoxemic mice through a heme oxygenase-1-dependent mechanism.
Acute Kidney Injury
Hyperbaric Oxygen Preconditioning Upregulates Heme OxyGenase-1 and Anti-Apoptotic Bcl-2 Protein Expression in Spontaneously Hypertensive Rats with Induced Postischemic Acute Kidney Injury.
Acute Kidney Injury
Hyperhomocysteinemia Accelerates Acute Kidney Injury to Chronic Kidney Disease Progression by Downregulating Heme Oxygenase-1 Expression.
Acute Kidney Injury
Immunohistochemical Analysis of 4-HNE, NGAL, and HO-1 Tissue Expression after Apocynin Treatment and HBO Preconditioning in Postischemic Acute Kidney Injury Induced in Spontaneously Hypertensive Rats.
Acute Kidney Injury
Induction of heme oxygenase in toxic renal injury: a protective role in cisplatin nephrotoxicity in the rat.
Acute Kidney Injury
Induction of heme oxygenase-1 in toxic renal injury: mercuric chloride-induced acute renal failure in rat.
Acute Kidney Injury
Inhibition of cytochrome P450 2E1 and activation of transcription factor Nrf2 are renoprotective in myoglobinuric acute kidney injury.
Acute Kidney Injury
Isoflavone and the heme oxygenase system in ischemic acute kidney injury in rats.
Acute Kidney Injury
Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury.
Acute Kidney Injury
Non-urate transporter 1, non-glucose transporter member 9-related renal hypouricemia and acute renal failure accompanied by hyperbilirubinemia after anaerobic exercise: a case report.
Acute Kidney Injury
Protective effect of carbon monoxide-releasing compounds in ischemia-induced acute renal failure.
Acute Kidney Injury
Protective effect of heme oxygenase induction in ischemic acute renal failure.
Acute Kidney Injury
Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury.
Acute Kidney Injury
Reactive oxygen and nitrogen species in the renal ischemia/reperfusion injury.
Acute Kidney Injury
Regulation and immunohistochemical analysis of stress protein heme oxygenase-1 in rat kidney with myoglobinuric acute renal failure.
Acute Kidney Injury
Rehmannia glutinose ameliorates renal function in the ischemia/reperfusion-induced acute renal failure rats.
Acute Kidney Injury
Tin chloride pretreatment prevents renal injury in rats with ischemic acute renal failure.
Acute Kidney Injury
Tin protoporphyrin activates the oxidant-dependent NRF2-cytoprotective pathway and mitigates acute kidney injury.
Acute Kidney Injury
Uremia induces proximal tubular cytoresistance and heme oxygenase-1 expression in the absence of acute kidney injury.
Acute Kidney Injury
Yukmijihwang-tang ameliorates ischemia/reperfusion-induced renal injury in rats.
Acute Lung Injury
A novel chalcone derivative, L2H17, ameliorates lipopolysaccharide-induced acute lung injury via upregulating HO-1 activity.
Acute Lung Injury
Absence of heme oxygenase-1 expression in the lung parenchyma exacerbates endotoxin-induced acute lung injury and decreases surfactant protein-B levels.
Acute Lung Injury
Acacetin attenuates mice endotoxin-induced acute lung injury via augmentation of heme oxygenase-1 activity.
Acute Lung Injury
AICAR decreases acute lung injury by phosphorylating AMPK and upregulating heme oxygenase-1.
Acute Lung Injury
Astragalin reduces lipopolysaccharide-induced acute lung injury in rats via induction of heme oxygenase-1.
Acute Lung Injury
Baicalin ameliorates lipopolysaccharide-induced acute lung injury in mice by suppressing oxidative stress and inflammation via the activation of the Nrf2-mediated HO-1 signaling pathway.
Acute Lung Injury
Combined Delivery of a Lipopolysaccharide-Binding Peptide and the Heme Oxygenase-1 Gene Using Deoxycholic Acid-Conjugated Polyethylenimine for the Treatment of Acute Lung Injury.
Acute Lung Injury
Combined delivery of curcumin and the heme oxygenase-1 gene using cholesterol-conjugated polyamidoamine for anti-inflammatory therapy in acute lung injury.
Acute Lung Injury
Effect of Radix Paeoniae Rubra on the expression of HO-1 and iNOS in rats with endotoxin-induced acute lung injury.
Acute Lung Injury
Effect of TLR-4 and HO-1 on acute lung injury induced by hemorrhagic shock in mice.
Acute Lung Injury
Effects of propofol pretreatment on lung morphology and heme oxygenase-1 expression in oleic acid-induced acute lung injury in rats.
Acute Lung Injury
Exhaled carbon monoxide and inducible heme oxygenase expression in a rat model of postperfusion acute lung injury.
Acute Lung Injury
GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation.
Acute Lung Injury
Heme oxygenase-1 ameliorates LPS-induced acute lung injury correlated with downregulation of interleukin-33.
Acute Lung Injury
Heme oxygenase-1 attenuates seawater drowning-induced acute lung injury through a reduction in inflammation and oxidative stress.
Acute Lung Injury
Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome.
Acute Lung Injury
Heme oxygenase-1 modulates thrombomodulin and activated protein c levels to attenuate lung injury in cecal ligation and puncture-induced acute lung injury mice.
Acute Lung Injury
Heme Oxygenase-1 Reduces Sepsis-Induced Endoplasmic Reticulum Stress and Acute Lung Injury.
Acute Lung Injury
Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor.
Acute Lung Injury
Heme oxygenase-1 upregulation significantly inhibits TNF-alpha and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in mice.
Acute Lung Injury
Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1.
Acute Lung Injury
Hyperbaric oxygen attenuation of lipopolysaccharide-induced acute lung injury involves heme oxygenase-1.
Acute Lung Injury
Hyperbaric oxygen preconditioning protects lung against hyperoxic acute lung injury in rats via heme oxygenase-1 induction.
Acute Lung Injury
Induction of heme oxygenase-1 by hemin protects lung against orthotopic autologous liver transplantation-induced acute lung injury in rats.
Acute Lung Injury
Mesenchymal stem cells overexpressing heme oxygenase-1 ameliorate lipopolysaccharide-induced acute lung injury in rats.
Acute Lung Injury
Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice.
Acute Lung Injury
Posttreatment with aspirin-triggered lipoxin A4 analog attenuates lipopolysaccharide-induced acute lung injury in mice: the role of heme oxygenase-1.
Acute Lung Injury
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system.
Acute Lung Injury
Pterostilbene 4'-?-Glucoside Attenuates LPS-Induced Acute Lung Injury via Induction of Heme Oxygenase-1.
Acute Lung Injury
Systemic perfluorohexane attenuates lung injury induced by lipopolysaccharide in rats: the role of heme oxygenase-1.
Acute Lung Injury
The protective effect of alpha-lipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1.
Acute Lung Injury
TLR4 REGULATE HEME OXYGENASE-1 EXPRESSION AFTER HEMORRHAGIC SHOCK INDUCED ACUTE LUNG INJURY IN MICE: REQUIREMENT OF p38MAPK ACTIVATION.
Acute Lung Injury
TLR4 signaling-induced heme oxygenase upregulation in the acute lung injury: role in hemorrhagic shock and two-hit induced lung inflammation.
Acute Lung Injury
Transfer of heme oxygenase 1 cDNA by a replication-deficient adenovirus enhances interleukin 10 production from alveolar macrophages that attenuates lipopolysaccharide-induced acute lung injury in mice.
Acute Lung Injury
[Effect of heme oxygenase-1 on the apoptosis of type II alveolar epithelial cells in rats with hyperoxia-induced acute lung injury].
Acute Lung Injury
[Role of heme oxygenase-1 in dachengqitang ameliorating lipopolysaccharide-induced acute lung injury in mice].
Adenocarcinoma
Clinicopathological and prognostic significance of heme oxygenase-1 expression in small intestinal adenocarcinomas.
Adenocarcinoma
Deuterium Oxide (D2O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma.
Adenocarcinoma
Heme oxygenase-1 gene promoter polymorphism is associated with risk of gastric adenocarcinoma and lymphovascular tumor invasion.
Adenocarcinoma
Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma.
Adenocarcinoma
HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer.
Adenocarcinoma
Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors.
Adenocarcinoma of Lung
Association of susceptibility to the development of lung adenocarcinoma with the heme oxygenase-1 gene promoter polymorphism.
Adenocarcinoma of Lung
Expression of heme oxygenase in arsenic-resistant human lung adenocarcinoma cells.
Adenocarcinoma of Lung
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Adenocarcinoma of Lung
Study on the Mechanism of Ginseng in the Treatment of Lung Adenocarcinoma Based on Network Pharmacology.
Adenocarcinoma of Lung
[Effects of heme oxygenase-1 knockdown on proliferation, invasion and metastasis of lung adenocarcinoma A549 cells and its mechanism].
Adenoma
Interplay of MKP-1 and Nrf2 drives tumor growth and drug resistance in non-small cell lung cancer.
Adenoma, Pleomorphic
Constitutive (HO-2) and inducible (HO-1) haem oxygenase in pleomorphic adenomas of the human parotid: an immunocytochemical study.
Adenomyosis
Expression of heme oxygenase in the eutopic and ectopic endometrium in patients with adenomyosis.
Albuminuria
Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study.
Albuminuria
Erratum: Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study: Erratum.
Alkalosis
The influence of exogenous carbohydrate provision and pre-exercise alkalosis on the heat shock protein response to prolonged interval cycling.
Alopecia Areata
Decreased heme oxygenase-1 expression in the scalp of patients with alopecia areata: the pathogenic role of heme oxygenase-1.
alpha-Thalassemia
Risk assessment of gene variants for neonatal hyperbilirubinemia in Taiwan.
Altitude Sickness
Heme oxygenase activity in fetal and adult sheep is not altered by acclimatization to high altitude hypoxia.
Alveolar Bone Loss
Simultaneous Quantitative Analysis of Ginsenosides Isolated from the Fruit of Panax ginseng C.A. Meyer and Regulation of HO-1 Expression through EGFR Signaling Has Anti-Inflammatory and Osteogenic Induction Effects in HPDL Cells.
Alveolar Bone Loss
Strontium Ranelate Elevates Expression of Heme Oxygenase-1 and Decreases Alveolar Bone Loss in Rats.
Alzheimer Disease
A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism.
Alzheimer Disease
Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease.
Alzheimer Disease
Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer's Disease.
Alzheimer Disease
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.
Alzheimer Disease
Bilirubin does not modulate ionotropic glutamate receptors or glutamate transporters.
Alzheimer Disease
Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain.
Alzheimer Disease
Biomarker potential of heme oxygenase-1 in Alzheimer's disease and mild cognitive impairment.
Alzheimer Disease
Characterization of alpha(1)-antitrypsin as a heme oxygenase-1 suppressor in Alzheimer plasma.
Alzheimer Disease
Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer's disease.
Alzheimer Disease
Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.
Alzheimer Disease
Early induction of oxidative stress in a mouse model of Alzheimer's disease with heme oxygenase activity.
Alzheimer Disease
Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk.
Alzheimer Disease
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment.
Alzheimer Disease
Heme oxygenase effect on mesenchymal stem cells action on experimental Alzheimer's disease.
Alzheimer Disease
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Alzheimer Disease
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment.
Alzheimer Disease
Heme oxygenase-1 protects against Alzheimer's amyloid-?(1-42)-induced toxicity via carbon monoxide production.
Alzheimer Disease
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Alzheimer Disease
Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
Alzheimer Disease
Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?
Alzheimer Disease
LXR-? genomics programmes neuronal death observed in Alzheimer's disease.
Alzheimer Disease
Neuroprotective effect of Annona muricata-derived polysaccharides in neuronal HT22 cell damage induced by hydrogen peroxide.
Alzheimer Disease
Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease.
Alzheimer Disease
No genetic association between polymorphisms of heme oxygenase 1 and 2 and Alzheimer's disease in a Japanese population.
Alzheimer Disease
Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease.
Alzheimer Disease
Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia.
Alzheimer Disease
Overexpression of heme oxygenase 1 causes cognitive decline and affects pathways for tauopathy in mice.
Alzheimer Disease
Overexpression of Heme Oxygenase 1 Impairs Cognitive Ability and Changes the Plasticity of the Synapse.
Alzheimer Disease
Oxidative and nitrosative modifications of biliverdin reductase-a in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment.
Alzheimer Disease
Pathogenesis of Alzheimer's disease and the role of heme oxygenase: new perspectives and hypothesis.
Alzheimer Disease
Possible assessment for antioxidant capacity in Alzheimer's disease by measuring lymphocyte heme oxygenase-1 expression with real-time RT-PCR.
Alzheimer Disease
Relationship between Brain Tissue Changes and Blood Biomarkers of Cyclophilin A, Heme Oxygenase-1, and Inositol-Requiring Enzyme 1 in Patients with Alzheimer's Disease.
Alzheimer Disease
Serum heme oxygenase-1 levels are increased in Parkinson's disease but not in Alzheimer's disease.
Alzheimer Disease
Synergistic Effect of Heme Oxygenase-1 and Tau Genetic Variants on Alzheimer's Disease Risk.
Alzheimer Disease
The balance mediated by miRNAs and the heme oxygenase 1 feedback loop contributes to biological effects.
Alzheimer Disease
The Neuroprotective and Neurodegeneration Effects of Heme Oxygenase-1 in Alzheimer's Disease.
Alzheimer Disease
The silent information regulator 1 pathway attenuates ROS-induced oxidative stress in Alzheimer's disease.
Alzheimer Disease
Ultrastructural localization of heme oxygenase-1 to the neurofibrillary pathology of Alzheimer disease.
Amnesia, Retrograde
Intrahippocampal, but not intra-amygdala, infusion of an inhibitor of heme oxygenase causes retrograde amnesia in the rat.
Amyotrophic Lateral Sclerosis
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Anaphylaxis
Effects of hyperthermia pretreatment on expression of heme oxygenase-1 and nitric oxide synthase in rats subjected to experimental anaphylactic shock.
Anemia
Dysfunction of the heme recycling system in heme oxygenase 1 deficient mice: effects on macrophage viability and tissue iron distribution.
Anemia
Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice.
Anemia
Heme oxygenase-1 induction by the ROS-JNK pathway plays a role in aluminum-induced anemia.
Anemia
Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development.
Anemia
Implication of HMOX1 and CCR5 genotypes on clinical phenotype of Egyptian patients with sickle cell anemia.
Anemia
Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice.
Anemia
Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a ?-thalassemia mouse model.
Anemia
Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation.
Anemia
Perfluorooctanoic acid (PFOA) exposure induces splenic atrophy via overactivation of macrophages in male mice.
Anemia
Polymorphism in the HMOX1 gene is associated with high levels of fetal hemoglobin in Brazilian patients with sickle cell anemia.
Anemia
Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients.
Anemia
Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state.
Anemia
Significance of heme oxygenase-1(HMOX1) gene on fetal hemoglobin induction in sickle cell anemia patients.
Anemia
Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine.
Anemia, Hemolytic
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Anemia, Hemolytic
Human spleen heme oxygenase in normal, hemolytic and other pathological states.
Anemia, Hemolytic
Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia.
Anemia, Hemolytic
Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha).
Anemia, Hemolytic
[Activity of key enzymes of heme metabolism and cytochrome P-450 content in the rat liver in experimental rhabdomyolysis and hemolytic anemia]
Anemia, Hemolytic
[Heme oxygenase induction in rat heart and vessels and peroxidative resistance of erythrocytes during hemolytic anemia development]
Anemia, Hemolytic, Autoimmune
Marked hyperbilirubinemia associated with the heme oxygenase-1 gene promoter microsatellite polymorphism in a boy with autoimmune hemolytic anemia.
Anemia, Hemolytic, Congenital
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.
Anemia, Hypochromic
Heme oxygenase induction. A possible factor in aluminum-associated anemia.
Anemia, Hypochromic
Young Leaf Chlorosis 2 encodes the stroma-localized heme oxygenase 2 which is required for normal tetrapyrrole biosynthesis in rice.
Anemia, Iron-Deficiency
Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state.
Anemia, Iron-Deficiency
Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine.
Anemia, Sickle Cell
Anomalous renal effects of tin protoporphyrin in a murine model of sickle cell disease.
Anemia, Sickle Cell
Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease.
Anemia, Sickle Cell
Clinical and genetic predictors of renal dysfunctions in sickle cell anaemia in Cameroon.
Anemia, Sickle Cell
Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
Anemia, Sickle Cell
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Anemia, Sickle Cell
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction.
Anemia, Sickle Cell
Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease.
Anemia, Sickle Cell
Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease.
Anemia, Sickle Cell
Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease.
Anemia, Sickle Cell
Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1.
Anemia, Sickle Cell
Implication of HMOX1 and CCR5 genotypes on clinical phenotype of Egyptian patients with sickle cell anemia.
Anemia, Sickle Cell
Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease.
Anemia, Sickle Cell
Polymorphism in the HMOX1 gene is associated with high levels of fetal hemoglobin in Brazilian patients with sickle cell anemia.
Anemia, Sickle Cell
Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients.
Anemia, Sickle Cell
Significance of heme oxygenase-1(HMOX1) gene on fetal hemoglobin induction in sickle cell anemia patients.
Anemia, Sickle Cell
The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease.
Anemia, Sickle Cell
The Role of Carbon Monoxide and Heme Oxygenase in the Prevention of Sickle Cell Disease Vaso-Occlusive Crises.
Anemia, Sickle Cell
Vasculoprotective Effects of Apolipoprotein Mimetic Peptides: An Evolving Paradigm In Hdl Therapy (Vascular Disease Prevention, In Press.).
Aneurysm
The Abdominal Aortic Aneurysm and Intraluminal Thrombus: Current Concepts of Development and Treatment.
Angina, Stable
Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients.
Aortic Aneurysm
Heme oxygenase-1 deficiency exacerbates angiotensin II-induced aortic aneurysm in mice.
Aortic Aneurysm, Abdominal
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Aortic Aneurysm, Abdominal
Biliverdin reductase deficiency triggers an endothelial-to-mesenchymal transition in human endothelial cells.
Aortic Aneurysm, Abdominal
GT Microsatellite Repeats in the Heme Oxygenase-1 Gene Promoter Associated with Abdominal Aortic Aneurysm in Croatian Patients.
Aortic Aneurysm, Abdominal
Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.
Aortic Aneurysm, Abdominal
Heme oxygenase-1 gene promoter polymorphism is associated with abdominal aortic aneurysm.
Aortic Valve Stenosis
Enhanced expression of hemoglobin scavenger receptor and heme oxygenase-1 is associated with aortic valve stenosis in patients undergoing hemodialysis.
Aortic Valve Stenosis
Simultaneous accurate quantification of HO-1, CD39, and CD73 in human calcified aortic valves using multiple enzyme digestion - filter aided sample pretreatment (MED-FASP) method and targeted proteomics.
Apnea
Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure.
Arteriosclerosis
A microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with increased bilirubin and HDL levels but not with coronary artery disease.
Arteriosclerosis
Adenovirus-mediated heme oxygenase transfer inhibits graft arteriosclerosis in rat aortic transplants.
Arteriosclerosis
Attenuation of aortic graft arteriosclerosis by systemic administration of Allotrap peptide RDP58.
Arteriosclerosis
Dendritic Cells Function in Transplantation Arteriosclerosis Is Regulated by Heme Oxygenase 1.
Arteriosclerosis
Eukaryotic expression vector of heme oxygenase-1 and its expression in endothelial cell.
Arteriosclerosis
Inhibition of graft arteriosclerosis development in rat aortas following heme oxygenase-1 gene transfer.
Arteriovenous Fistula
A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1.
Arteriovenous Fistula
Far infrared therapy inhibits vascular endothelial inflammation via the induction of heme oxygenase-1.
Arteriovenous Fistula
Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse.
Arteriovenous Fistula
Length polymorphism in heme oxygenase-1 is associated with arteriovenous fistula patency in hemodialysis patients.
Arteriovenous Fistula
Length polymorphisms of heme oxygenase-1 determine the effect of far-infrared therapy on the function of arteriovenous fistula in hemodialysis patients: a novel physicogenomic study.
Arthralgia
Amelioration of human osteoarthritis symptoms with topical 'biotherapeutics': a phase I human trial.
Arthritis
Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat.
Arthritis
Anti-inflammatory, anti-rheumatic and analgesic activities of 2-(5-mercapto-1,3,4-oxadiazol-2-yl)-N-propylbenzenesulphonamide (MOPBS) in rodents.
Arthritis
Heme oxygenase-1 end-products carbon monoxide and biliverdin ameliorate murine collagen induced arthritis.
Arthritis
Heme oxygenase-1/biliverdin/carbon monoxide pathway downregulates hypernociception in rats by a mechanism dependent on cGMP/ATP-sensitive K
Arthritis
Inhibition of transcription factors by plant-derived compounds and their implications in inflammation and cancer.
Arthritis
Pharmacologic induction of heme oxygenase 1 reduces acute inflammatory arthritis in mice.
Arthritis
Protective effect of Chresta martii extract on the zymosan-induced temporomandibular joint arthritis in rats.
Arthritis
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.
Arthritis
Up-Regulation of the Inflammatory Response by Ovariectomy in Collagen-Induced Arthritis. Effects of Tin Protoporphyrin IX.
Arthritis, Experimental
Effects of heme oxygenase-1 inducers on established rat adjuvant arthritis.
Arthritis, Experimental
Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis.
Arthritis, Experimental
Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis.
Arthritis, Experimental
Protective effect of higenamine ameliorates collagen-induced arthritis through heme oxygenase-1 and PI3K/Akt/Nrf-2 signaling pathways.
Arthritis, Experimental
Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect.
Arthritis, Experimental
Rebamipide suppresses collagen-induced arthritis through reciprocal regulation of th17/treg cell differentiation and heme oxygenase 1 induction.
Arthritis, Experimental
Rebamipide suppresses collagen-induced arthritis through reciprocal regulation of Th17/Treg differentiation and heme oxygenase-1 induction.
Arthritis, Juvenile
HMOX1 promoter (GT)n polymorphim is associated with childhood-onset systemic lupus erythematosus but not with juvenile rheumatoid arthritis in a Mexican population.
Arthritis, Juvenile
The role of heme oxygenase-1 in systemic-onset juvenile idiopathic arthritis.
Arthritis, Rheumatoid
"Breathing" Micelles for Combinatorial Treatment of Rheumatoid Arthritis.
Arthritis, Rheumatoid
Bach1 regulates osteoclastogenesis via both heme oxygenase-1 dependent and independent pathways.
Arthritis, Rheumatoid
Calycosin suppresses expression of pro-inflammatory cytokines via the activation of p62/Nrf2-linked heme oxygenase 1 in rheumatoid arthritis synovial fibroblasts.
Arthritis, Rheumatoid
Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction.
Arthritis, Rheumatoid
Comparative study of HO-1 expressing synovial lining cells between RA and OA.
Arthritis, Rheumatoid
Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis.
Arthritis, Rheumatoid
HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis.
Arthritis, Rheumatoid
Increased level of heme oxygenase-1 in rheumatoid arthritis synovial fluid.
Arthritis, Rheumatoid
Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis.
Arthritis, Rheumatoid
Serum Heme Oxygenase-1 and BMP-7 Are Potential Biomarkers for Bone Metabolism in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis.
Arthritis, Rheumatoid
Sour cherry (Prunus cerasus) seed extract increases heme oxygenase-1 expression and decreases proinflammatory signaling in peripheral blood human leukocytes from rheumatoid arthritis patients.
Ascorbic Acid Deficiency
Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Asthma
Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model.
Asthma
Anti-asthmatic effects of Angelica dahurica against ovalbumin-induced airway inflammation via upregulation of heme oxygenase-1.
Asthma
Anti-inflammatory, immunomodulatory, and heme oxygenase-1 inhibitory activities of ravan napas, a formulation of uighur traditional medicine, in a rat model of allergic asthma.
Asthma
Antioxidant genes and susceptibility to air pollution for respiratory and cardiovascular health.
Asthma
Heme oxygenase-1 inhibits basophil maturation and activation but promotes its apoptosis in T helper type 2-mediated allergic airway inflammation.
Asthma
Heme oxygenase-1 protects airway epithelium against apoptosis by targeting the proinflammatory NLRP3-RXR axis in asthma.
Asthma
Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation.
Asthma
Opposing effects of nasal epithelial NAD(P)H dehydrogenase quinine 1 and heme oxygenase 1 expression on upper and lower airway symptoms in adolescents with asthma.
Asthma
Protective effects of Ulmus davidiana var. japonica against OVA-induced murine asthma model via upregulation of heme oxygenase-1.
Asthma
Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress.
Asthma
Suppression of heme oxygenase-1 activity reduces airway hyperresponsiveness and inflammation in a mouse model of asthma.
Asthma
The PPAR? agonist, rosiglitazone, attenuates airway inflammation and remodeling via heme oxygenase-1 in murine model of asthma.
Asthma
Up-regulation of heme oxygenase-I in alveolar macrophages of newly diagnosed asthmatics.
Asthma
[Effect of budesonide on the heme oxygenase-1 expression in lung tissues of rats with asthma]
Asthma
[Experimental study on the effect of ginkgo bioba extract on the expression of heme oxygenase-1 in bronchial asthma].
Astrocytoma
Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma.
Ataxia
Glial HMOX1 expression promotes central and peripheral ?-synuclein dysregulation and pathogenicity in parkinsonian mice.
Ataxia
Parkinsonian features in aging GFAP.HMOX1 transgenic mice overexpressing human HO-1 in the astroglial compartment.
Ataxia
Strategic Timing of Glial HMOX1 Expression Results in Either Schizophrenia-Like or Parkinsonian Behavior in Mice.
Ataxia Telangiectasia
Ataxia telangiectasia mutated inhibits oxidative stress-induced apoptosis by regulating heme oxygenase-1 expression.
Ataxia Telangiectasia
Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein.
Atherosclerosis
3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells.
Atherosclerosis
Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis
Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging.
Atherosclerosis
Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease.
Atherosclerosis
Brain microvascular and intracranial artery resistance to atherosclerosis is associated with heme oxygenase and ferritin in Japanese quail.
Atherosclerosis
CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages.
Atherosclerosis
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: A critical role for heme oxygenase-1.
Atherosclerosis
Differential response of vascular smooth muscle cells to oxidized LDL in mouse strains with different atherosclerosis susceptibility.
Atherosclerosis
Dual anti-oxidative effects of fraxetin isolated from Fraxinus rhinchophylla.
Atherosclerosis
Effects of induction/inhibition of endogenous heme oxygenase-1 on lipid metabolism, endothelial function, and atherosclerosis in rabbits on a high fat diet.
Atherosclerosis
Effects of Induction/Inhibition of Endogenous Heme Oxygenase-1 on Lipid Metabolism, Endothelial Function, and Atherosclerosis in Rabbits on a High Fat Diet.
Atherosclerosis
Effects of oxidant-induced injury on heme oxygenase and glutathione in cultured aortic endothelial cells from atherosclerosis-susceptible and -resistant Japanese quail.
Atherosclerosis
Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice.
Atherosclerosis
Epigallocatechin gallate-mediated protection against tumor necrosis factor-?-induced monocyte chemoattractant protein-1 expression is heme oxygenase-1 dependent.
Atherosclerosis
Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement.
Atherosclerosis
Ginkgo biloba extract reduces high-glucose-induced endothelial reactive oxygen species generation and cell adhesion molecule expression by enhancing HO-1 expression via Akt/eNOS and p38 MAP kinase pathways.
Atherosclerosis
Heme oxygenase 1 determines atherosclerotic lesion progression into a vulnerable plaque.
Atherosclerosis
Heme oxygenase as an intrinsic defense system in vascular wall: implication against atherogenesis.
Atherosclerosis
Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.
Atherosclerosis
Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease.
Atherosclerosis
Heme oxygenase-1 inhibits atherogenesis in Watanabe heritable hyperlipidemic rabbits.
Atherosclerosis
Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis.
Atherosclerosis
Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy.
Atherosclerosis
Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress-A New Insight into the Pathophysiology of Vascular Diseases.
Atherosclerosis
HO-1 and VGEF gene expression in human arteries with advanced atherosclerosis.
Atherosclerosis
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2.
Atherosclerosis
Lunasin attenuates oxidant-induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE-/- mice by up-regulating heme oxygenase-1 via PI3K/Akt/Nrf2/ARE pathway.
Atherosclerosis
Mechanism of heme oxygenase-1 gene induction by quercetin in rat aortic smooth muscle cells.
Atherosclerosis
Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury.
Atherosclerosis
Oxidative stress mediates sodium arsenite-induced expression of heme oxygenase-1, monocyte chemoattractant protein-1, and interleukin-6 in vascular smooth muscle cells.
Atherosclerosis
Paradoxical protection from atherosclerosis and thrombosis in a mouse model of sickle cell disease.
Atherosclerosis
Protective role of heme oxygenase in the blood vessel wall during atherogenesis.
Atherosclerosis
Protective role of heme oxygenase-1 against inflammation in atherosclerosis.
Atherosclerosis
Quercetin Inhibited Endothelial Dysfunction and Atherosclerosis in Apolipoprotein E-Deficient Mice: Critical Roles for NADPH Oxidase and Heme Oxygenase-1.
Atherosclerosis
Salvianolic acid B inhibits atherogenesis of vascular cells through induction of Nrf2-dependent heme oxygenase-1.
Atherosclerosis
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
Atherosclerosis
Spirulina platensis and phycocyanobilin activate atheroprotective heme oxygenase-1: a possible implication for atherogenesis.
Atherosclerosis
Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1.
Atherosclerosis
Structural requirements of flavonoids to induce heme oxygenase-1 expression.
Atherosclerosis
Targeting Vascular Redox Biology Through Antioxidant Gene Delivery: A Historical View and Current Perspectives.
Atherosclerosis
The Association between Serum Heme Oxygenase-1 Levels and Coronary SYNTAX Score.
Atherosclerosis
YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.
Atherosclerosis
[Assessment of oxidative stress in patients with atherosclerosis focusing on heme oxygenase]
Atrial Fibrillation
Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling.
Atrial Fibrillation
Microsatellite polymorphism in the heme oxygenase-1 gene promoter and the risk of atrial fibrillation in Taiwanese.
Atrial Fibrillation
The Association between Heme Oxygenase-1 Gene Promoter Polymorphism and the Outcomes of Catheter Ablation of Atrial Fibrillation.
Autoimmune Diseases
5-Aminolevulinic acid regulates the inflammatory response and alloimmune reaction.
Autoimmune Diseases
Functional Immunoregulation by Heme Oxygenase 1 in Juvenile Autoimmune Diseases.
Autoimmune Diseases
Heme oxygenase-1 as a target for the design of gene and pharmaceutical therapies for autoimmune diseases.
Avitaminosis
Activity of xenobiotic-metabolizing enzymes in the liver of rats with multi-vitamin deficiency.
Bacterial Infections
Association of genetic polymorphisms and risk of late post-transplantation infection in pediatric heart recipients.
Bacterial Infections
Bacteroides fragilis enterotoxin upregulates heme oxygenase-1 in dendritic cells via reactive oxygen species-, mitogen-activated protein kinase-, and Nrf2-dependent pathway.
Bacterial Infections
Heme Oxygenase-1 Deficiency Diminishes Methicillin-Resistant Staphylococcus aureus Clearance Due to Reduced TLR9 Expression in Pleural Mesothelial Cells.
Bacterial Infections
Heme oxygenase-1 induction by cobalt protoporphyrin enhances fever and inhibits pyrogenic tolerance to lipopolysaccharide.
Bacterial Infections
Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1.
Bacterial Infections
Low-dose immune challenges result in detectable levels of oxidative damage.
Bacterial Infections
Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation.
Bacterial Infections
Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils.
Bacterial Infections
The immune function of heme oxygenase-1 from grass carp (Ctenopharyngodon idellus) in response to bacterial infection.
Behcet Syndrome
Association of Reduced Heme Oxygenase-1 with Decreased MicroRNA-196a2 Expression in Peripheral Blood Mononuclear Cells of Patients with Intestinal Behcet's Disease.
Blister
Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery.
Bone Neoplasms
[Overexpression of heme oxygenase 1 in spinal cord alleviates bone cancer pain in mice].
Bone Resorption
Deltamethrin inhibits osteoclast differentiation via regulation of heme oxygenase-1 and NFATc1.
Bone Resorption
Heme oxygenase-1 protects human periodontal ligament cells against substance P-induced RANKL expression.
Brain Death
Brain dead donor kidneys are immunologically active: is intervention justified?
Brain Death
Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70.
Brain Death
Norepinephrine and arginine vasopressin increase hepatic but not renal inflammatory activation during hemodynamic resuscitation in a rodent model of brain-dead donors.
Brain Death
Sumoylation of hypoxia-inducible factor-1? ameliorates failure of brain stem cardiovascular regulation in experimental brain death.
Brain Diseases
A Heme Oxygenase-1 Transducer Model of Degenerative and Developmental Brain Disorders.
Brain Diseases
Heme oxygenase-1 modulates microRNA expression in cultured astroglia: implications for chronic brain disorders.
Brain Edema
Cerebral hemorrhage, brain edema, and heme oxygenase-1 expression after experimental traumatic brain injury.
Brain Edema
Effects of heme oxygenase 1 on brain edema and neurologic outcome after cardiopulmonary resuscitation in rats.
Brain Edema
Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage.
Brain Edema
miR-24 targets HMOX1 to regulate inflammation and neurofunction in rats with cerebral vasospasm after subarachnoid hemorrhage.
Brain Edema
Neuroprotective potential of GDF11 in experimental intracerebral hemorrhage in elderly rats.
Brain Edema
Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in mice.
Brain Edema
Role of Oleanolic acid in maintaining BBB integrity by targeting p38MAPK/VEGF/Src signaling pathway in rat model of subarachnoid hemorrhage.
Brain Edema
Systemic zinc protoporphyrin administration reduces intracerebral hemorrhage-induced brain injury.
Brain Injuries
A new antioxidant compound H-290/51 attenuates nitric oxide synthase and heme oxygenase expression following hyperthermic brain injury. An experimental study using immunohistochemistry in the rat.
Brain Injuries
Carbon monoxide potentiation of L-type Ca2+ channel activity increases HIF-1?-independent VEGF expression via an AMPK?/SIRT1-mediated PGC-1?/ERR? axis.
Brain Injuries
Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells.
Brain Injuries
Curcumin attenuates hypoxic-ischemic brain injury in neonatal rats through induction of nuclear factor erythroid-2-related factor 2 and heme oxygenase-1.
Brain Injuries
Deferoxamine Alleviates Iron Overload and Brain Injury in a Rat Model of Brainstem Hemorrhage.
Brain Injuries
Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage.
Brain Injuries
Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.
Brain Injuries
Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage.
Brain Injuries
Heme Oxygenase-1 Mediated Memorial and Revivable Protective Effect of Ischemic Preconditioning on Brain Injury.
Brain Injuries
Heme Oxygenase-1 Mediates Neuroprotection Conferred by Argon in Combination with Hypothermia in Neonatal Hypoxia-Ischemia Brain Injury.
Brain Injuries
Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways.
Brain Injuries
High-Glucose-Derived Oxidative Stress-Dependent Heme Oxygenase-1 Expression from Astrocytes Contributes to the Neuronal Apoptosis.
Brain Injuries
Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain injury.
Brain Injuries
Neuroprotective effects of valproic acid against hemin toxicity: Possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway.
Brain Injuries
Reactive Oxygen Species-Dependent c-Fos/Activator Protein 1 Induction Upregulates Heme Oxygenase-1 Expression by Bradykinin in Brain Astrocytes.
Brain Injuries
Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats.
Brain Injuries
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Brain Injuries
Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy.
Brain Injuries
Research Progress in Understanding the Relationship Between Heme Oxygenase-1 and Intracerebral Hemorrhage.
Brain Injuries
Role of heme oxygenase in heme-mediated inhibition of rat brain Na+-K+-ATPase: protection by tin-protoporphyrin.
Brain Injuries
Shogaol but not gingerol has a neuroprotective effect on hemorrhagic brain injury: Contribution of the ?, ?-unsaturated carbonyl to heme oxygenase-1 expression.
Brain Injuries
The deleterious or beneficial effects of different agents in intracerebral hemorrhage: think big, think small, or is hematoma size important?
Brain Injuries
The Gene Coexpression Analysis Identifies Functional Modules Dynamically Changed After Traumatic Brain Injury.
Brain Injuries
Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury.
Brain Injuries, Traumatic
Cerebral hemorrhage, brain edema, and heme oxygenase-1 expression after experimental traumatic brain injury.
Brain Injuries, Traumatic
Exercise preconditioning improves traumatic brain injury outcomes.
Brain Injuries, Traumatic
Heme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury.
Brain Injuries, Traumatic
Heme oxygenase-2 modulates early pathogenesis after traumatic injury to the immature brain.
Brain Injuries, Traumatic
Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury.
Brain Injuries, Traumatic
Immunohistochemical study on the induction of heme oxygenase-1 by traumatic brain injury.
Brain Injuries, Traumatic
Increased miR-155 and heme oxygenase-1 expression is involved in the protective effects of formononetin in traumatic brain injury in rats.
Brain Injuries, Traumatic
Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat.
Brain Injuries, Traumatic
Induction of heme oxygenase-1 (HO-1) in glia after traumatic brain injury.
Brain Injuries, Traumatic
Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain injury.
Brain Injuries, Traumatic
Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans.
Brain Injuries, Traumatic
N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury.
Brain Injuries, Traumatic
Nutraceutical induction and mimicry of heme oxygenase activity as a strategy for controlling excitotoxicity in brain trauma and ischemic stroke: focus on oxidative stress.
Brain Injuries, Traumatic
Time-dependent hemeoxygenase-1, lipocalin-2 and ferritin induction after non-contusion traumatic brain injury.
Brain Injuries, Traumatic
Toll-like receptor 2 contributes to glial cell activation and heme oxygenase-1 expression in traumatic brain injury.
Brain Ischemia
Cerebral heme oxygenase 1 and 2 spatial distribution is modulated following injury from hypoxia-ischemia and middle cerebral artery occlusion in rats.
Brain Ischemia
Changes of hypoxia-inducible factor-1 signaling and the effect of cilostazol in chronic cerebral ischemia.
Brain Ischemia
Ebselen lowers plasma interleukin-6 levels and glial heme oxygenase-1 expression after focal photothrombotic brain ischemia.
Brain Ischemia
Expression of heme oxygenase-1 protein and messenger RNA in permanent cerebral ischemia in rats.
Brain Ischemia
Ginkgo biloba Extract Prevents Female Mice from Ischemic Brain Damage and the Mechanism Is Independent of the HO1/Wnt Pathway.
Brain Ischemia
Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia.
Brain Ischemia
Heme oxygenase-1 regulates the JNK signaling pathway through the MLK3-MKK7-JNK3 signaling module in brain ischemia injury.
Brain Ischemia
Induction of heme oxygenase protein protects neurons in cortex and striatum, but not in hippocampus, against transient forebrain ischemia.
Brain Ischemia
Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice.
Brain Ischemia
Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain.
Brain Ischemia
Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury.
Brain Ischemia
Quantitative imaging mass spectroscopy reveals roles of heme oxygenase-2 for protecting against transhemispheric diaschisis in the brain ischemia.
Brain Ischemia
Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats.
Brain Ischemia
Simvastatin-induced heme oxygenase-1 increases apoptosis of Neuro 2A cells in response to glucose deprivation.
Brain Ischemia
Stress-responsive heme oxygenase-1 isoenzyme participates in Toll-like receptor 4-induced inflammation during brain ischemia.
Brain Ischemia
Tetramethylpyrazine inhibits neutrophil activation following permanent cerebral ischemia in rats.
Brain Ischemia
Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats.
Brain Ischemia
Tin-mesoporphyrin, a potent heme oxygenase inhibitor, for treatment of intracerebral hemorrhage: in vivo and in vitro studies.
Brain Ischemia
Up-regulation of heme oxygenase-1 attenuates brain damage after cerebral ischemia via simultaneous inhibition of superoxide production and preservation of NO bioavailability.
Brain Neoplasms
Expression of heme oxygenase and inducible nitric oxide synthase mRNA in human brain tumors.
Brain Neoplasms
Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model.
Breast Neoplasms
15-Deoxy-?(12,14)-prostaglandin J2 Induces p53 Expression through Upregulation of Heme Oxygenase-1 in Human Breast Cancer (MCF-7) Cells.
Breast Neoplasms
15-Deoxy-?12,14-prostaglandin J2 Upregulates VEGF Expression via NRF2 and Heme Oxygenase-1 in Human Breast Cancer Cells.
Breast Neoplasms
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
Breast Neoplasms
BMP-6 inhibits MMP-9 expression by regulating heme oxygenase-1 in MCF-7 breast cancer cells.
Breast Neoplasms
Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells.
Breast Neoplasms
Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2.
Breast Neoplasms
EIF2A promotes cell survival during paclitaxel treatment in vitro and in vivo.
Breast Neoplasms
Evaluation of biological activities of a groundnut (Apios americana Medik) extract containing a novel isoflavone.
Breast Neoplasms
Expression of nerve growth factor and heme oxygenase-1 predict poor survival of breast carcinoma patients.
Breast Neoplasms
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.
Breast Neoplasms
Heme Oxygenase-1 and Breast Cancer Resistance Protein Protect Against heme-induced toxicity.
Breast Neoplasms
Heme oxygenase-1 determines the differential response of breast cancer and normal cells to piperlongumine.
Breast Neoplasms
Heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to pharmorubicin by promoting autophagy via PI3K/Akt pathway.
Breast Neoplasms
Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9.
Breast Neoplasms
Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase.
Breast Neoplasms
Heme Oxygenase-1 Inhibits Tumor Metastasis Mediated By Notch1 Pathway In Murine Mammary Carcinoma.
Breast Neoplasms
Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells.
Breast Neoplasms
Inhibition Of Fatty Acid Amide Hydrolase Activates Nrf2 Signaling And Induces Heme Oxygenase 1 Transcription In Breast Cancer Cells.
Breast Neoplasms
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells.
Breast Neoplasms
Knockdown of heme oxygenase-1 promotes apoptosis and autophagy and enhances the cytotoxicity of doxorubicin in breast cancer cells.
Breast Neoplasms
Mutant p53 tunes the NRF2-dependent antioxidant response to support survival of cancer cells.
Breast Neoplasms
Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk.
Breast Neoplasms
Plasmatic hypercoagulation in patients with breast cancer: role of heme oxygenase-1.
Breast Neoplasms
Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1.
Breast Neoplasms
Role of heme oxygenase-1 and its reaction product, carbon monoxide, in manifestation of breast cancer stem cell-like properties: Notch-1 as a putative target.
Breast Neoplasms
Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells.
Breast Neoplasms
Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy.
Breast Neoplasms
The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide.
Breast Neoplasms
The role of functional polymorphisms in oxidative stress-related genes on early-stage breast cancer survival.
Bronchiolitis
Graft protective effects of heme oxygenase 1 in mouse tracheal transplant-related obliterative bronchiolitis.
Bronchiolitis Obliterans
Heme oxygenase-1 expression in alveolar macrophages is elevated in patients with bronchiolitis obliterans syndrome after lung transplantation.
Bronchitis
Reciprocal regulation of airway rejection by the inducible gas-forming enzymes heme oxygenase and nitric oxide synthase.
Bronchopulmonary Dysplasia
Genetic Contributions to the Development of Complications in Preterm Newborns.
Bronchopulmonary Dysplasia
Vasculoprotective effects of heme oxygenase-1 in a murine model of hyperoxia-induced bronchopulmonary dysplasia.
Candidemia
Candida albicans heme oxygenase and its product CO contribute to pathogenesis of candidemia and alter systemic chemokine and cytokine expression.
Carcinogenesis
Arsenite, but not cadmium, induces ornithine decarboxylase and heme oxygenase activity in rat liver: relevance to arsenic carcinogenesis.
Carcinogenesis
Bach1 deficiency and accompanying overexpression of heme oxygenase-1 do not influence aging or tumorigenesis in mice.
Carcinogenesis
Cell cycle arrest and modulation of HO-1 expression induced by acetyl salicylic acid in hepatocarcinogenesis.
Carcinogenesis
Dimethylarsinic acid treatment alters six different rat biochemical parameters: relevance to arsenic carcinogenesis.
Carcinogenesis
Enhancement of DEN-induced liver tumorigenesis in heme oxygenase-1 G143H mutant transgenic mice.
Carcinogenesis
Fraxetin Induces Heme Oxygenase-1 Expression by Activation of Akt/Nrf2 or AMP-activated Protein Kinase ?/Nrf2 Pathway in HaCaT Cells.
Carcinogenesis
Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer.
Carcinogenesis
Heme Oxygenase-1 Is a Pivotal Modulator of Bone Turnover and Remodeling: Molecular Implications for Prostate Cancer Bone Metastasis.
Carcinogenesis
Marliolide inhibits skin carcinogenesis by activating NRF2/ARE to induce heme oxygenase-1.
Carcinogenesis
Nrf2-Keap1 Signaling as a Potential Target for Chemoprevention of Inflammation-Associated Carcinogenesis.
Carcinogenesis
Pharmacological versus genetic inhibition of heme oxygenase-1 - the comparison of metalloporphyrins, shRNA and CRISPR/Cas9 system.
Carcinogenesis
The Galpha12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis.
Carcinogenesis
Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPK? as upstream targets.
Carcinogenesis
Transforming growth factor-? induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.
Carcinogenesis
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation.
Carcinoma
Antioxidation and Antiapoptosis Characteristics of Heme Oxygenase-1 Enhance Tumorigenesis of Human Prostate Carcinoma Cells.
Carcinoma
Antitumor Effect of 5-Aminolevulinic Acid Through Ferroptosis in Esophageal Squamous Cell Carcinoma.
Carcinoma
Arsenic methylation capability, heme oxygenase-1 and NADPH quinone oxidoreductase-1 genetic polymorphisms and the stage and grade of urothelial carcinomas.
Carcinoma
Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma.
Carcinoma
Chrysosplenol D Triggers Apoptosis through Heme Oxygenase-1 and Mitogen-Activated Protein Kinase Signaling in Oral Squamous Cell Carcinoma.
Carcinoma
Clinicopathological and prognostic significance of heme oxygenase-1 expression in small intestinal adenocarcinomas.
Carcinoma
Effect of cisplatin and cobalt chloride on antioxidant enzymes in the livers of Lewis lung carcinoma-bearing mice: protective role of heme oxygenase.
Carcinoma
Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
Carcinoma
Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate.
Carcinoma
Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis.
Carcinoma
Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas.
Carcinoma
Heme Oxygenase-1 Inhibits Tumor Metastasis Mediated By Notch1 Pathway In Murine Mammary Carcinoma.
Carcinoma
Heme oxygenase-1 is a predictive biomarker for therapeutic targeting of advanced clear cell renal cell carcinoma treated with sorafenib or sunitinib.
Carcinoma
Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder.
Carcinoma
Honokiol inhibits c-Met-HO-1 tumor-promoting pathway and its cross-talk with calcineurin inhibitor-mediated renal cancer growth.
Carcinoma
Individual and co-expression patterns of nerve growth factor and heme oxygenase-1 predict shorter survival of gastric carcinoma patients.
Carcinoma
Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis.
Carcinoma
Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients.
Carcinoma
MiR-200c sensitizes clear-cell renal cell carcinoma cells to sorafenib and imatinib by targeting heme oxygenase-1.
Carcinoma
Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas.
Carcinoma
Polymorphism in heme oxygenase-1 (HO-1) promoter and alcohol are related to the risk of esophageal squamous cell carcinoma on Chinese males.
Carcinoma
Polymorphism in heme oxygenase-1 (HO-1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers.
Carcinoma
Prediction of radiosensitivity in human esophageal squamous cell carcinomas with heme oxygenase-1: a clinicopathological and immunohistochemical study.
Carcinoma
Protease-activated receptor 2 modulates proliferation and invasion of oral squamous cell carcinoma cells.
Carcinoma
The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells.
Carcinoma
The Usage of Curcumin as Chemopreventive Agent for Oral Squamous Cell Carcinoma: An Experimental Study on Sprague-Dawley Rat.
Carcinoma
Upregulation of heme oxygenase-1 expression in areca-quid-chewing-associated oral squamous cell carcinoma.
Carcinoma
Upregulation of Ying Yang 1 (YY1) suppresses esophageal squamous cell carcinoma development through heme oxygenase-1.
Carcinoma
[The risk of esophageal squamous cell carcinoma associated with microsatellite polymorphism in promoter of heme oxygenase-1].
Carcinoma, Hepatocellular
14-3-3? inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Carcinoma, Hepatocellular
A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene.
Carcinoma, Hepatocellular
A high expression of heme oxygenase-1 in the liver of LEC rats at the stage of hepatoma: the possible implication of induction in uninvolved tissue.
Carcinoma, Hepatocellular
Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells.
Carcinoma, Hepatocellular
Alternative 5' Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1.
Carcinoma, Hepatocellular
Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats.
Carcinoma, Hepatocellular
Carbon monoxide mediates heme oxygenase 1 induction via Nrf2 activation in hepatoma cells.
Carcinoma, Hepatocellular
Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells.
Carcinoma, Hepatocellular
CYP2E1 overexpression up-regulates both non-specific delta-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1.
Carcinoma, Hepatocellular
Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity.
Carcinoma, Hepatocellular
Effect of interleukin-11 on the levels of mRNAs encoding heme oxygenase and haptoglobin in human HepG2 hepatoma cells.
Carcinoma, Hepatocellular
Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells.
Carcinoma, Hepatocellular
Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxygenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells.
Carcinoma, Hepatocellular
HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells.
Carcinoma, Hepatocellular
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.
Carcinoma, Hepatocellular
Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.
Carcinoma, Hepatocellular
Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3- dependent apoptosis in human hepatoma cell line.
Carcinoma, Hepatocellular
Heme oxygenase-1 induction by heat shock in rat hepatoma cell line is regulated by the coordinated function of HSF1, NRF2, AND BACH1.
Carcinoma, Hepatocellular
Heme oxygenase-1 retards hepatocellular carcinoma progression through the microRNA pathway.
Carcinoma, Hepatocellular
Heme oxygenase-1: a molecular brake on hepatocellular carcinoma cell migration.
Carcinoma, Hepatocellular
Heme-hemopexin-mediated induction of metallothionein gene expression.
Carcinoma, Hepatocellular
Human Heme Oxygenase-1 Induced by Interleukin-6 via JAK/STAT3 Pathways Is a Tumor Suppressor Gene in Hepatoma Cells.
Carcinoma, Hepatocellular
Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines. A possible strategy for the maintenance of intracellular heme level.
Carcinoma, Hepatocellular
Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.
Carcinoma, Hepatocellular
Induction of heme oxygenase in rat hepatoma cells by exposure to heavy metals and hyperthermia.
Carcinoma, Hepatocellular
Interaction of hemopexin with Sn-protoporphyrin IX, an inhibitor of heme oxygenase. Role for hemopexin in hepatic uptake of Sn-protoporphyrin IX and induction of mRNA for heme oxygenase.
Carcinoma, Hepatocellular
Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
Carcinoma, Hepatocellular
Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV.
Carcinoma, Hepatocellular
Mechanism of Action of Sulforaphane: Inhibition of p38 Mitogen-Activated Protein Kinase Isoforms Contributing to the Induction of Antioxidant Response Element-Mediated Heme Oxygenase-1 in Human Hepatoma HepG2 Cells.
Carcinoma, Hepatocellular
Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
Carcinoma, Hepatocellular
MiRNA-15a-3p inhibits the metastasis of hepatocellular carcinoma by interacting with HMOX1.
Carcinoma, Hepatocellular
Nrf2-mediated induction of detoxifying enzymes by alantolactone present in Inula helenium.
Carcinoma, Hepatocellular
Phloretamide, an apple phenolic compound, activates the Nrf2/ARE pathway in human hepatocytes.
Carcinoma, Hepatocellular
Receptor-mediated transport of heme by hemopexin regulates gene expression in mammalian cells.
Carcinoma, Hepatocellular
Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron.
Carcinoma, Hepatocellular
SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Carcinoma, Hepatocellular
Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression.
Carcinoma, Hepatocellular
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.
Carcinoma, Hepatocellular
The therapeutic benefits of heme oxygenase (HO-1) inhibition in the management of systemic malignancies besides hepatocellular carcinomas.
Carcinoma, Hepatocellular
Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells.
Carcinoma, Hepatocellular
Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements.
Carcinoma, Hepatocellular
Using the gene expression signature of scutebarbalactone VN isolated from Scutellaria barbata to elucidate its anticancer activities.
Carcinoma, Hepatocellular
[Protective effect of HIF-1alpha-dependent HO-1 overexpression on hypoxic human hepatoma cells in vitro]
Carcinoma, Lewis Lung
Effect of cisplatin and cobalt chloride on antioxidant enzymes in the livers of Lewis lung carcinoma-bearing mice: protective role of heme oxygenase.
Carcinoma, Mucoepidermoid
Heme Oxygenase-1 is a Key Molecule Underlying Differential Response of TW-37-Induced Apoptosis in Human Mucoepidermoid Carcinoma Cells.
Carcinoma, Non-Small-Cell Lung
Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.
Carcinoma, Non-Small-Cell Lung
Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data.
Carcinoma, Non-Small-Cell Lung
High expression of heme oxygenase-1 is associated with tumor invasiveness and poor clinical outcome in non-small cell lung cancer patients.
Carcinoma, Non-Small-Cell Lung
Inhibition of heme oxygenase-1 enhances the radiosensitivity in human nonsmall cell lung cancer a549 cells.
Carcinoma, Non-Small-Cell Lung
Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis.
Carcinoma, Non-Small-Cell Lung
MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1.
Carcinoma, Non-Small-Cell Lung
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation.
Carcinoma, Renal Cell
Heme oxygenase-1 is a predictive biomarker for therapeutic targeting of advanced clear cell renal cell carcinoma treated with sorafenib or sunitinib.
Carcinoma, Renal Cell
Honokiol inhibits c-Met-HO-1 tumor-promoting pathway and its cross-talk with calcineurin inhibitor-mediated renal cancer growth.
Carcinoma, Renal Cell
Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells.
Carcinoma, Renal Cell
MiR-200c sensitizes clear-cell renal cell carcinoma cells to sorafenib and imatinib by targeting heme oxygenase-1.
Carcinoma, Renal Cell
Quantitative measurement of heme oxygenase-1 in the human renal adenocarcinoma.
Carcinoma, Squamous Cell
Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
Carcinoma, Squamous Cell
Enhancement of heme oxygenase expression and activity in A431 squamous carcinoma multicellular tumor spheroids.
Carcinoma, Squamous Cell
Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas.
Carcinoma, Squamous Cell
Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas.
Carcinoma, Squamous Cell
Prediction of radiosensitivity in human esophageal squamous cell carcinomas with heme oxygenase-1: a clinicopathological and immunohistochemical study.
Cardio-Renal Syndrome
OX-HDL: A Starring Role in Cardiorenal Syndrome and the Effects of Heme Oxygenase-1 Intervention.
Cardiomegaly
Altered expression of the natriuretic peptide system in genetically modified heme oxygenase-1 mice treated with high dietary salt.
Cardiomegaly
Astragaloside IV Exerts a Myocardial Protective Effect against Cardiac Hypertrophy in Rats, Partially via Activating the Nrf2/HO-1 Signaling Pathway.
Cardiomegaly
Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo.
Cardiomegaly
Interaction among heme oxygenase, nuclear factor-kappaB, and transcription activating factors in cardiac hypertrophy in hypertension.
Cardiomegaly
Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats.
Cardiomegaly
Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats.
Cardiomegaly
Systemic Heme Oxygenase-1 Transgenic Overexpression Aggravates Pressure Overload-induced Cardiac Hypertrophy in Mice.
Cardiomegaly
The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model.
Cardiomegaly
The effect of a preparation of minerals, vitamins and trace elements on the cardiac gene expression pattern in male diabetic rats.
Cardiomegaly
[Simvastatin inhibits hypertension-induced cardiac hypertrophy in rats through activation of heme oxygenase-1/carbon monoxide pathway.]
Cardiomyopathies
Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1.
Cardiomyopathies
Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy.
Cardiomyopathies
EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice.
Cardiomyopathies
Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
Cardiomyopathies
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Cardiomyopathies
Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Cardiomyopathies
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1.
Cardiomyopathies
Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress.
Cardiotoxicity
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Cardiotoxicity
Crocin ameliorates arsenic trioxide?induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Cardiotoxicity
Non-mitogenic FGF2 protects cardiomyocytes from acute doxorubicin-induced toxicity independently of the protein kinase CK2/heme oxygenase-1 pathway.
Cardiovascular Diseases
An update of the effect of far infrared therapy on arteriovenous access in end-stage renal disease patients.
Cardiovascular Diseases
Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases.
Cardiovascular Diseases
Cardioprotective Effects of Sour Cherry Seed Extract (SCSE) on the Hypercholesterolemic Rabbit Heart.
Cardiovascular Diseases
CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.
Cardiovascular Diseases
Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies.
Cardiovascular Diseases
Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression.
Cardiovascular Diseases
Evidence for a Possible Inhibitory Interaction between the HO-1/CO- and Akt/NO-Pathways in Human Endothelial Cells.
Cardiovascular Diseases
Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?
Cardiovascular Diseases
Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (the Ludwigshafen Risk and Cardiovascular Health study).
Cardiovascular Diseases
Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase.
Cardiovascular Diseases
Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease.
Cardiovascular Diseases
Heme oxygenase-1 in cardiovascular diseases: molecular mechanisms and clinical perspectives.
Cardiovascular Diseases
Heme oxygenase-1 transgenic overexpression did not prevent artery injury induced by electric stimulation and pressure overload in mice.
Cardiovascular Diseases
Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease.
Cardiovascular Diseases
Hmox1 (Heme Oxygenase-1) Protects Against Ischemia-Mediated Injury via Stabilization of HIF-1? (Hypoxia-Inducible Factor-1?).
Cardiovascular Diseases
HMOX1 gene promoter polymorphism is not associated with coronary artery disease in Koreans.
Cardiovascular Diseases
Plasma bilirubin values on admission and ventricular remodeling after a first anterior ST-segment elevation acute myocardial infarction.
Cardiovascular Diseases
Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases.
Cardiovascular Diseases
Quercetin, but not rutin, attenuated hydrogen peroxide-induced cell damage via heme oxygenase-1 induction in endothelial cells.
Cardiovascular Diseases
Role of heme oxygenase-1 in cardiovascular diseases: a novel target for molecular intervention?
Cardiovascular Diseases
Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells.
Cardiovascular Diseases
The role of statins in heme oxygenase-1 activation in cardiovascular diseases.
Cardiovascular Diseases
The size of a microsatellite polymorphism of the haem oxygenase 1 gene is associated with idiopathic recurrent miscarriage.
Cardiovascular Diseases
Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway.
Cardiovascular Diseases
Xinmailong Attenuates Doxorubicin-Induced Lysosomal Dysfunction and Oxidative Stress in H9c2 Cells via HO-1.
Cardiovascular Diseases
Xyloketal B Exhibits Its Antioxidant Activity through Induction of HO-1 in Vascular Endothelial Cells and Zebrafish.
Carotid Artery Diseases
GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure.
Catalepsy
Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll-like receptor 4, TGF-?1, NF-?B and glucagon-like peptide 1.
Cataract
Bioinformatics analysis of microarray data to explore the key genes involved in HSF4 mutation-induced cataract.
Central Nervous System Diseases
Heme oxygenase expression in human central nervous system disorders.
Cerebral Hemorrhage
Astrocyte heme oxygenase-1 reduces mortality and improves outcome after collagenase-induced intracerebral hemorrhage.
Cerebral Hemorrhage
Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome After Intracerebral Hemorrhage.
Cerebral Hemorrhage
Attenuation of oxidative injury after induction of experimental intracerebral hemorrhage in heme oxygenase-2 knockout mice.
Cerebral Hemorrhage
Cerebral hemorrhage, brain edema, and heme oxygenase-1 expression after experimental traumatic brain injury.
Cerebral Hemorrhage
Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage.
Cerebral Hemorrhage
Distinct role of heme oxygenase-1 in early- and late-stage intracerebral hemorrhage in 12-month-old mice.
Cerebral Hemorrhage
Expression changes of inflammatory cytokines TNF-?, IL-1? and HO-1 in hematoma surrounding brain areas after intracerebral hemorrhage.
Cerebral Hemorrhage
Fenofibrate increases heme oxygenase 1 expression and astrocyte proliferation while limits neuronal injury during intracerebral hemorrhage.
Cerebral Hemorrhage
Fenofibrate Increases Heme Oxygenase 1 Expression and Astrocyte Proliferation While Limits Neuronal Injury During Intracerebral Hemorrhage.
Cerebral Hemorrhage
Heme oxygenase 1 plays role of neuron-protection by regulating Nrf2-ARE signaling post intracerebral hemorrhage.
Cerebral Hemorrhage
Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage.
Cerebral Hemorrhage
Heme oxygenase in experimental intracerebral hemorrhage: the benefit of tin-mesoporphyrin.
Cerebral Hemorrhage
Heme oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage.
Cerebral Hemorrhage
Higher Level of Serum Heme Oxygenase-1 in Patients With Intracerebral Hemorrhage.
Cerebral Hemorrhage
HO-1 protects the nerves of rats with cerebral hemorrhage by regulating the PI3K/AKT signaling pathway.
Cerebral Hemorrhage
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states.
Cerebral Hemorrhage
miR-183-5p alleviates early injury after intracerebral hemorrhage by inhibiting heme oxygenase-1 expression.
Cerebral Hemorrhage
Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage.
Cerebral Hemorrhage
Neuroprotective effects of valproic acid against hemin toxicity: Possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway.
Cerebral Hemorrhage
Research Progress in Understanding the Relationship Between Heme Oxygenase-1 and Intracerebral Hemorrhage.
Cerebral Hemorrhage
The deleterious or beneficial effects of different agents in intracerebral hemorrhage: think big, think small, or is hematoma size important?
Cerebral Hemorrhage
The role of heme oxygenase-1 (HO-1) in the regulation of inflammatory reaction, neuronal cell proliferation and apoptosis in rats after intracerebral hemorrhage (ICH).
Cerebral Hemorrhage
Time course of heme oxygenase-1 and oxidative stress after experimental intracerebral hemorrhage.
Cerebral Hemorrhage
Time course of increased heme oxygenase activity and expression after experimental intracerebral hemorrhage: correlation with oxidative injury.
Cerebral Hemorrhage
Tin-mesoporphyrin, a potent heme oxygenase inhibitor, for treatment of intracerebral hemorrhage: in vivo and in vitro studies.
Cerebral Hemorrhage
[Expressions of heme oxygenase-1 and apoptosis-modulating proteins in peri-hematomal cortex after intracerebral hemorrhage in human being]
Cerebral Infarction
Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement.
Cerebral Infarction
Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans.
Chemical and Drug Induced Liver Injury
Possible association of HMOX1 and NQO1 polymorphisms with anti-tuberculosis drug-induced liver injury: A matched case-control study.
Cholangiocarcinoma
Crucial role of heme oxygenase-1 on the sensitivity of cholangiocarcinoma cells to chemotherapeutic agents.
Cholangiocarcinoma
Enhancement of piperlongumine chemosensitivity by silencing heme oxygenase-1 expression in cholangiocarcinoma cell lines.
Cholangiocarcinoma
Growth inhibitory effect of ?-eudesmol on cholangiocarcinoma cells and its potential suppressive effect on heme oxygenase-1 production, STAT1/3 activation, and NF-?B downregulation.
Cholangiocarcinoma
Haem oxygenase 1 expression is associated with prognosis in cholangiocarcinoma patients and with drug sensitivity in xenografted mice.
Cholelithiasis
The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease.
Cholestasis
Curcumin ameliorates hepatic chronic inflammation induced by bile duct obstruction in mice through the activation of heme oxygenase-1.
Cholestasis
Effect of cholestasis produced by bile duct ligation on hepatic heme and hemoprotein metabolism in rats.
Cholestasis
Heme oxygenase-1 induction by hemin prevents oxidative stress-induced acute cholestasis in the rat.
Cholestasis
Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis.
Cholestasis
The effect of heme oxygenase on ganglioside redistribution within hepatocytes in experimental estrogen-induced cholestasis.
Cholestasis, Intrahepatic
Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy.
Choriocarcinoma
Expression of placenta growth factor, soluble fms-like tyrosine kinase-1, metal-responsive transcription factor-1, heme oxygenase 1 and hypoxia inducible factor-1? mRNAs in pre-eclampsia placenta and the effect of pre-eclampsia sera on their expression of choriocarcinoma cells.
Choriocarcinoma
Transcriptome analysis of human cancer reveals a functional role of Heme Oxygenase-1 in tumor cell adhesion.
Classical Swine Fever
Down-regulation of cellular protein heme oxygenase 1 inhibits proliferation of classical swine fever virus in PK-15 cells.
Cleft Palate
[Expression of sHsps of normal palate and cleft palate during mouse embryogenesis]
Coinfection
Hepatic HMOX1 expression positively correlates with Bach-1 and miR-122 in patients with HCV mono and HIV/HCV coinfection.
Colitis
15-Deoxy-?12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.
Colitis
2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways.
Colitis
An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis.
Colitis
BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-1.
Colitis
Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway.
Colitis
Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance.
Colitis
Dietary ?-linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis.
Colitis
Dietary quercetin ameliorates experimental colitis in mouse by remodeling the function of colonic macrophages via a heme oxygenase-1-dependent pathway.
Colitis
Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice: evidence of the connection between heme oxygenase-1 and the nuclear factor-kappaB pathway in vitro and in vivo.
Colitis
H2S confers colonoprotection against TNBS-induced colitis by HO-1 upregulation in rats.
Colitis
Heme oxygenase-1 ameliorates dextran sulfate sodium-induced acute murine colitis by regulating Th17/Treg cell balance.
Colitis
Heme Oxygenase-1 Induction and Anti-inflammatory Actions of Atractylodes macrocephala and Taraxacum herba Extracts Prevented Colitis and Was More Effective than Sulfasalazine in Preventing Relapse.
Colitis
Host nuclear factor erythroid 2-related factor-2 defense system determines the outcome of dextran sulfate sodium-induced colitis in mice.
Colitis
Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation.
Colitis
Nrf2 is not required for epithelial prohibitin-dependent attenuation of experimental colitis.
Colitis
Oral delivery of Lactococcus lactis that secretes bioactive heme oxygenase-1 alleviates development of acute colitis in mice.
Colitis
Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1? protein by inhibiting HIF prolyl hydroxylase.
Colitis
Protective role of heme oxygenase-1 on trinitrobenzene sulfonic acid-induced colitis in rats.
Colitis
Rectal administration of tranilast ameliorated acute colitis in mice through increased expression of heme oxygenase-1.
Colitis
The effect of heme oxygenase-1 induction by glutamine on TNBS-induced colitis. The effect of glutamine on TNBS colitis.
Colitis
The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis.
Colitis
Ziziphus spina-christi fruit extract suppresses oxidative stress and p38 MAPK expression in ulcerative colitis in rats via induction of Nrf2 and HO-1 expression.
Colitis, Ulcerative
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.
Colitis, Ulcerative
Increased intestinal expression of heme oxygenase-1 and its localization in patients with ulcerative colitis.
Colitis, Ulcerative
Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation.
Colonic Neoplasms
15-Deoxy-?12,14-prostaglandin J2 Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells.
Colonic Neoplasms
Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice.
Colonic Neoplasms
Epidermal growth factor stimulates nuclear factor-?B activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Colonic Neoplasms
Erratum: 15-Deoxy-?12,14-prostaglandin J2 Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells.
Colonic Neoplasms
Heme induces DNA damage and hyperproliferation of colonic epithelial cells via hydrogen peroxide produced by heme oxygenase: A possible mechanism of heme-induced colon cancer.
Colonic Neoplasms
Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway.
Colonic Neoplasms
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity.
Colonic Neoplasms
Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.
Colonic Neoplasms
Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer.
Colonic Neoplasms
The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells.
Colorectal Neoplasms
A new chalcone derivative, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)prop-2-yn-1-one), inhibits phorbol ester-induced metastatic activity of colorectal cancer cells through upregulation of heme oxygenase-1.
Colorectal Neoplasms
Association of serum bilirubin and promoter variations in HMOX1 and UGT1A1 genes with sporadic colorectal cancer.
Colorectal Neoplasms
Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer.
Colorectal Neoplasms
Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer.
Colorectal Neoplasms
Heme oxygenase-1 has antitumoral effects in colorectal cancer: involvement of p53.
Colorectal Neoplasms
Heme oxygenase-1 polymorphism is not associated with risk of colorectal cancer: a Danish prospective study.
Colorectal Neoplasms
Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity.
Colorectal Neoplasms
No association between HMOX1 and risk of colorectal cancer and no interaction with diet and lifestyle factors in a prospective Danish case-cohort study.
Colorectal Neoplasms
The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer.
Colorectal Neoplasms
Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity.
Communicable Diseases
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.
Communicable Diseases
Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages.
Corneal Edema
Hemin Promotes Corneal Allograft Survival Through the Suppression of Macrophage Recruitment and Activation.
Corneal Edema
Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery.
Coronary Artery Disease
A microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with increased bilirubin and HDL levels but not with coronary artery disease.
Coronary Artery Disease
Association Between Heme Oxygenase 1 Gene Promoter Polymorphisms and Susceptibility to Coronary Artery Disease: A HuGE Review and Meta-Analysis.
Coronary Artery Disease
Association of Genetic Variations in NRF2, NQO1, HMOX1, and MT with Severity of Coronary Artery Disease and Related Risk Factors.
Coronary Artery Disease
Blood levels of heme oxygenase-1 versus bilirubin in patients with coronary artery disease.
Coronary Artery Disease
Correlation between genetic polymorphisms within the MAPK1/HIF-1/HO-1 signaling pathway and risk or prognosis of perimenopausal coronary artery disease.
Coronary Artery Disease
Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (the Ludwigshafen Risk and Cardiovascular Health study).
Coronary Artery Disease
GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan.
Coronary Artery Disease
Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors.
Coronary Artery Disease
HMOX1 gene promoter polymorphism is not associated with coronary artery disease in Koreans.
Coronary Artery Disease
Intragraft heme oxygenase-1 and coronary artery disease after heart transplantation.
Coronary Artery Disease
Length Polymorphism in Heme Oxygenase-1 and Risk of CKD among Patients with Coronary Artery Disease.
Coronary Artery Disease
Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients.
Coronary Artery Disease
Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study.
Coronary Artery Disease
Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis.
Coronary Artery Disease
Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients.
Coronary Artery Disease
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Coronary Artery Disease
Shorter GT repeats in the heme oxygenase-1 gene promoter are associated with a lower severity score in coronary artery disease.
Coronary Artery Disease
Subjects with coronary artery disease and reduced ejection fraction have longer (GT)n repeats in the heme-oxygenase 1 gene promoter.
Coronary Artery Disease
The prediction of coronary artery disease based on non-invasive examinations and heme oxygenase 1 polymorphism versus virtual histology.
Coronary Artery Disease
[Assessment of oxidative stress in patients with atherosclerosis focusing on heme oxygenase]
Coronary Disease
Expression of heme oxygenase-1, hypoxia inducible factor-1alpha, and ubiquitin in peripheral inflammatory cells from patients with coronary heart disease.
Coronary Disease
Heme oxygenase-1 gene promoter polymorphisms are associated with coronary heart disease and restenosis after percutaneous coronary intervention: a meta-analysis.
Coronary Disease
Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
Coronary Disease
Short (GT) ( n ) repeats in heme oxygenase-1 gene promoter are associated with lower risk of coronary heart disease in subjects with high levels of oxidative stress.
Coronary Disease
Study on changes of heme oxygenase-1 expression in patients with coronary heart disease.
Coronary Thrombosis
Hypoxic regulation of cardiac Ca2+ channel: possible role of haem oxygenase.
Corticobasal Degeneration
Evidence for oxidative stress in Pick disease and corticobasal degeneration.
COVID-19
Chlorogenic acid, a natural product as potential inhibitor of COVID-19: virtual screening experiment based on network pharmacology and molecular docking.
COVID-19
Correction to: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.
COVID-19
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.
COVID-19
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1.
COVID-19
Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases.
COVID-19
Heme oxygenase-1 (HO-1) cytoprotective pathway: A potential treatment strategy against coronavirus disease 2019 (COVID-19)-induced cytokine storm syndrome.
COVID-19
Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications.
COVID-19
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
COVID-19
The HMOX1 Pathway as a Promising Target for the Treatment and Prevention of SARS-CoV-2 of 2019 (COVID-19).
Craniocerebral Trauma
N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury.
Crigler-Najjar Syndrome
Pharmacological and biological effects of tin-protoporphyrin on neonatal hyperbilirubinemic Gunn rats.
Crohn Disease
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.
Crohn Disease
Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation.
Cystadenocarcinoma, Serous
A Network Pharmacology-Based Analysis of Multi-Target, Multi-Pathway, Multi-Compound Treatment for Ovarian Serous Cystadenocarcinoma.
Cystic Fibrosis
Exhaled carbon monoxide concentration increases after exercise in children with cystic fibrosis.
Cystic Fibrosis
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
Cystic Fibrosis
Heme oxygenase-1 expression in human lungs with cystic fibrosis and cytoprotective effects against Pseudomonas aeruginosa in vitro.
Cystic Fibrosis
Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator.
Cystic Fibrosis
Targeting the Heme Oxygenase 1/Carbon Monoxide Pathway to Resolve Lung Hyper-Inflammation and Restore a Regulated Immune Response in Cystic Fibrosis.
Cystitis
Protective effects of bilirubin against cyclophosphamide induced hemorrhagic cystitis in rats.
Cystitis
Protective effects of heme oxygenase-1 against cyclophosphamide-induced haemorrhagic cystitis in rats.
Cysts
Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease.
Dementia
Heme Oxygenase-1 Activity as a Correlate to Exercise-Mediated Amelioration of Cognitive Decline and Neuropathological Alterations in an Aging Rat Model of Dementia.
Dementia, Vascular
Increased HO-1 expression and decreased iNOS expression in the hippocampus from adult spontaneously hypertensive rats.
Demyelinating Diseases
Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders.
Demyelinating Diseases
Stress proteins in oligodendrocytes: differential effects of heat shock and oxidative stress.
Dengue
(E)-Guggulsterone Inhibits Dengue Virus Replication by Upregulating Antiviral Interferon Responses through the Induction of Heme Oxygenase-1 Expression.
Dengue
Antibodies against dengue virus nonstructural protein-1 induce heme oxygenase-1 via a redox-dependent pathway in human endothelial cells.
Dengue
Human heme oxygenase 1 is a potential host cell factor against dengue virus replication.
Dengue
Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1.
Dermatitis, Atopic
Cell-penetrating heme oxygenase-1 in the therapy of atopic dermatitis in mice.
Dermatitis, Atopic
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin.
Dermatitis, Contact
Heme oxygenase (HO-1) is involved in the negative regulation of contact sensitivity reaction.
Dermatitis, Contact
Heme oxygenase-1 attenuates contact hypersensitivity induced by 2,4-dinitrofluorobenzene in mice.
Dermatitis, Phototoxic
Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells.
Diabetes Complications
Heme oxygenase-1, a novel target for the treatment of diabetic complications: focus on diabetic peripheral neuropathy.
Diabetes Mellitus
Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes in a Chinese population.
Diabetes Mellitus
Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes mellitus: a HuGE review and meta-analysis.
Diabetes Mellitus
CHRONIC TEMPOL TREATMENT ATTENUATES THE RENAL HEMODYNAMIC EFFECTS INDUCED BY A HEME OXYGENASE INHIBITOR IN STREPTOZOTOCIN DIABETIC RATS.
Diabetes Mellitus
CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.
Diabetes Mellitus
Effects of Losartan, HO-1 Inducers or HO-1 Inhibitors on Erectile Signaling in Diabetic Rats.
Diabetes Mellitus
Haem oxygenases play a pivotal role in placental physiology and pathology.
Diabetes Mellitus
Heme oxygenase microsatellite polymorphism, oxidative stress, glycemic control, and complication development in type 2 diabetes patients.
Diabetes Mellitus
Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress-A New Insight into the Pathophysiology of Vascular Diseases.
Diabetes Mellitus
Maternal serum heme-oxygenase-1 (HO-1) concentrations in early pregnancy and subsequent risk of gestational diabetes mellitus.
Diabetes Mellitus
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with iron status in persons with type 2 diabetes mellitus.
Diabetes Mellitus
Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study.
Diabetes Mellitus
Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus.
Diabetes Mellitus
Short repeats in the heme oxygenase 1 gene promoter is associated with increased levels of inflammation, ferritin and higher risk of type-2 diabetes mellitus.
Diabetes Mellitus
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Diabetes Mellitus, Type 1
Adeno-associated virus (AAV) as a vehicle for therapeutic gene delivery: improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet cell transplantation for the reversal of type 1 diabetes.
Diabetes Mellitus, Type 1
Elevated catalase and heme oxygenase-1 may contribute to improved postischaemic cardiac function in long-term type 1 diabetes.
Diabetes Mellitus, Type 1
Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice.
Diabetes Mellitus, Type 1
Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes.
Diabetes Mellitus, Type 1
Heme Oxygenase-1 Induction Prevents Autoimmune Diabetes in Association With Pancreatic Recruitment of M2-Like Macrophages, Mesenchymal Cells, and Fibrocytes.
Diabetes Mellitus, Type 1
Proteomic characterization of pancreatic islet {beta}-cells stimulated with pancreatic carcinoma cell conditioned medium.
Diabetes Mellitus, Type 1
Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice.
Diabetes Mellitus, Type 1
The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice.
Diabetes Mellitus, Type 2
Administration of heme arginate ameliorates murine type 2 diabetes independently of heme oxygenase activity.
Diabetes Mellitus, Type 2
Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes in a Chinese population.
Diabetes Mellitus, Type 2
Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes mellitus: a HuGE review and meta-analysis.
Diabetes Mellitus, Type 2
Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study.
Diabetes Mellitus, Type 2
Cross-Talk Between Body Iron Stores and Diabetes: Iron Stores are Associated with Activity and Microsatellite Polymorphism of the Heme Oxygenase and Type 2 Diabetes.
Diabetes Mellitus, Type 2
Erratum: Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study: Erratum.
Diabetes Mellitus, Type 2
Expression levels of enzymes generating NO and CO in islets of murine and human diabetes.
Diabetes Mellitus, Type 2
Heme oxygenase microsatellite polymorphism, oxidative stress, glycemic control, and complication development in type 2 diabetes patients.
Diabetes Mellitus, Type 2
Heme oxygenase-1 in type 2 diabetes: from cell first-line defense to early marker of diabetic nephropathy.
Diabetes Mellitus, Type 2
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism.
Diabetes Mellitus, Type 2
Liraglutide reduces oxidative stress and restores heme oxygenase-1 and ghrelin levels in patients with type 2 diabetes: a prospective pilot study.
Diabetes Mellitus, Type 2
Maternal serum heme-oxygenase-1 (HO-1) concentrations in early pregnancy and subsequent risk of gestational diabetes mellitus.
Diabetes Mellitus, Type 2
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with iron status in persons with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study.
Diabetes Mellitus, Type 2
Plasma heme oxygenase-1 concentration in relation to impaired glucose regulation in a non-diabetic Chinese population.
Diabetes Mellitus, Type 2
Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Sour Cherry Seed Kernel Extract Increases Heme Oxygenase-1 Expression and Decreases Representation of CD3+ TNF-??+?and CD3?+?IL-8+ Subpopulations in Peripheral Blood Leukocyte Cultures from Type 2 Diabetes Patients.
Diabetes Mellitus, Type 2
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Diabetes Mellitus, Type 2
The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice.
Diabetes Mellitus, Type 2
Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance.
Diabetes Mellitus, Type 2
Upregulation of the heme oxygenase system ameliorates postprandial and fasting hyperglycemia in type 2 diabetes.
Diabetes, Gestational
Effect of oxidative stress on heme oxygenase-1 expression in patients with gestational diabetes mellitus.
Diabetic Cardiomyopathies
miR-503 Is Involved in the Protective Effect of Phase II Enzyme Inducer (CPDT) in Diabetic Cardiomyopathy via Nrf2/ARE Signaling Pathway.
Diabetic Cardiomyopathies
The heme oxygenase system selectively enhances the anti-inflammatory macrophage-M2 phenotype, reduces pericardial adiposity and ameliorated cardiac injury in diabetic cardiomyopathy in Zucker diabetic fatty rats.
Diabetic Cardiomyopathies
The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy.
Diabetic Nephropathies
Heme oxygenase-1 in type 2 diabetes: from cell first-line defense to early marker of diabetic nephropathy.
Diabetic Nephropathies
Modulation of heme oxygenase-1 expression and activity affects streptozotocin-induced diabetic nephropathy in rats.
Diabetic Nephropathies
Nrf-2 mediated heme oxygenase-1 activation contributes to the anti-inflammatory and renal protective effects of Ginkgo biloba extract in diabetic nephropathy.
Diabetic Nephropathies
Protective Effects of Luteolin on Diabetic Nephropathy in STZ-Induced Diabetic Rats.
Diabetic Nephropathies
Sitagliptin improves renal function in diabetic nephropathy in male Sprague Dawley rats through upregulating heme oxygenase-1 expression.
Diabetic Nephropathies
Targeting heme oxygenase-1 in early diabetic nephropathy in streptozotocin-induced diabetic rats.
Diabetic Nephropathies
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Diabetic Nephropathies
The heme oxygenase system suppresses perirenal visceral adiposity, abates renal inflammation and ameliorates diabetic nephropathy in Zucker diabetic fatty rats.
Diabetic Nephropathies
Urinary Heme Oxygenase-1 as a potential biomarker for early diabetic nephropathy.
Diabetic Neuropathies
The antinociceptive effects of a ?-opioid receptor agonist in mice with painful diabetic neuropathy: Involvement of heme oxygenase 1.
Diabetic Neuropathies
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Diabetic Neuropathies
The role of carbon monoxide on the anti-nociceptive effects and expression of cannabinoid 2 receptors during painful diabetic neuropathy in mice.
Diabetic Retinopathy
Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine.
Diabetic Retinopathy
Association of HMGB1 with oxidative stress markers and regulators in PDR.
Diabetic Retinopathy
Pharmacologic Induction of Heme Oxygenase-1 Plays a Protective Role in Diabetic Retinopathy in Rats.
Diabetic Retinopathy
Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression.
Diabetic Retinopathy
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Diaschisis
Quantitative imaging mass spectroscopy reveals roles of heme oxygenase-2 for protecting against transhemispheric diaschisis in the brain ischemia.
Diffuse Axonal Injury
Sulforaphane administration alleviates diffuse axonal injury (DAI) via regulation signaling pathway of NRF2 and HO-1.
Diphtheria
NMR assignments of cd-HO, a 24 kDa heme oxygenase from Corynebacterium diphtheria.
Distemper
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
dna 5'-3' helicase deficiency
Bach1 deficiency and accompanying overexpression of heme oxygenase-1 do not influence aging or tumorigenesis in mice.
dna 5'-3' helicase deficiency
Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1.
Drug-Related Side Effects and Adverse Reactions
Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes.
Dyslipidemias
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Encephalitis
Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection.
Encephalitis, Herpes Simplex
Microglia are the major cellular source of inducible nitric oxide synthase during experimental herpes encephalitis.
Encephalomyelitis
Daphnetin Ameliorates Experimental Autoimmune Encephalomyelitis Through Regulating Heme Oxygenase-1.
Encephalomyelitis
Heme oxygenase-1 in lesions of rat experimental autoimmune encephalomyelitis and neuritis.
Encephalomyelitis
Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis.
Encephalomyelitis
Quantifying immunohistochemical staining of phospho-eIF2alpha, heme oxygenase-2 and NADPH cytochrome P450 reductase in oligodendrocytes during experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Daphnetin Ameliorates Experimental Autoimmune Encephalomyelitis Through Regulating Heme Oxygenase-1.
Encephalomyelitis, Autoimmune, Experimental
Effect of dimethyl fumarate on heme oxygenase-1 expression in experimental allergic encephalomyelitis in rats.
Encephalomyelitis, Autoimmune, Experimental
Heme oxygenase-1 and NADPH cytochrome P450 reductase expression in experimental allergic encephalomyelitis: an expanded view of the stress response.
Encephalomyelitis, Autoimmune, Experimental
Heme oxygenase-1 in lesions of rat experimental autoimmune encephalomyelitis and neuritis.
Encephalomyelitis, Autoimmune, Experimental
Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Quantifying immunohistochemical staining of phospho-eIF2alpha, heme oxygenase-2 and NADPH cytochrome P450 reductase in oligodendrocytes during experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
[Dynamic changes of heme oxygenase-1 protein and mRNA in the brains of rats with experimental allergic encephalomyelitis]
Encephalomyelitis, Autoimmune, Experimental
[The dynamic changes of heme oxygenase-1 mRNA and protein express at subfornical organ in rats with experimental allergic encephalomyelitis].
Endometriosis
A delicate redox balance between iron and heme oxygenase-1 as an essential biological feature of endometriosis.
Endometriosis
Autophagy is upregulated in ovarian endometriosis: a possible interplay with p53 and heme oxygenase-1.
Endometriosis
Clinical significance of M2 macrophages expressing heme oxygenase-1 in malignant transformation of ovarian endometrioma.
Endometriosis
Comparison of redox parameters in ovarian endometrioma and its malignant transformation.
Endometriosis
Endometriosis Is Associated with Functional Polymorphism in the Promoter of Heme Oxygenase 1 (HMOX1) Gene.
Endotoxemia
Alanyl-glutamine dipeptide does not affect hemodynamics despite a greater increase in myocardial heat shock protein 72 immunoreactivity in endotoxemic sheep.
Endotoxemia
Alteration in heme oxygenase-1 and nitric oxide synthase-2 gene expression during endotoxemia in cyclooxygenase-2-deficient mice.
Endotoxemia
Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia.
Endotoxemia
Gelam honey inhibits lipopolysaccharide-induced endotoxemia in rats through the induction of heme oxygenase-1 and the inhibition of cytokines, nitric oxide, and high-mobility group protein B1.
Endotoxemia
Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia.
Endotoxemia
Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1.
Endotoxemia
Hemoglobin-based oxygen carrier induces heme oxygenase-1 in the heart and lung but not brain.
Endotoxemia
High Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1 Deficient Mice.
Endotoxemia
Induction of heme oxygenase-1 during endotoxemia is downregulated by transforming growth factor-beta1.
Endotoxemia
Intragastric administration with recombinant Lactococcus lactis producing heme oxygenase-1 prevents lipopolysaccharide-induced endotoxemia in rats.
Endotoxemia
Reciprocal regulation of IL-6 and IL-10 balance by HGF via recruitment of heme oxygenase-1 in macrophages for attenuation of liver injury in a mouse model of endotoxemia.
Endotoxemia
The lower intestinal tract-specific induction of heme oxygenase-1 by glutamine protects against endotoxemic intestinal injury.
Endotoxemia
The reciprocal relationship between heme oxygenase and nitric oxide synthase in the organs of lipopolysaccharide-treated rodents.
Endotoxemia
Tin-mesoporphyrin for inhibition of heme oxygenase during long-term hyperdynamic porcine endotoxemia.
Enteritis
Crystal structure of Campylobacter jejuni ChuZ: a split-barrel family heme oxygenase with a novel heme-binding mode.
Enteritis
Protective roles of CX3CR1-mediated signals in toxin A-induced enteritis through the induction of heme oxygenase-1 expression.
Enteritis
The effect of heme oxygenase-1 induction by glutamine on radiation-induced intestinal damage: the effect of heme oxygenase-1 on radiation enteritis.
Erectile Dysfunction
The potential role of the heme oxygenase/carbon monoxide system in male sexual dysfunctions.
Erectile Dysfunction
[Expression of heme oxygenase in the corpus cavernosum of castrated rats]
Esophageal and Gastric Varices
Study of the influence of heme oxygenase 1 gene single nucleotide polymorphism (rs2071746) on esophageal varices among patients with cirrhosis.
Esophageal Neoplasms
Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine.
Esophageal Neoplasms
Prediction of radiosensitivity in human esophageal squamous cell carcinomas with heme oxygenase-1: a clinicopathological and immunohistochemical study.
Esophageal Neoplasms
Upregulation of Ying Yang 1 (YY1) suppresses esophageal squamous cell carcinoma development through heme oxygenase-1.
Esophageal Neoplasms
[The risk of esophageal squamous cell carcinoma associated with microsatellite polymorphism in promoter of heme oxygenase-1].
Esophageal Squamous Cell Carcinoma
Antitumor Effect of 5-Aminolevulinic Acid Through Ferroptosis in Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
Polymorphism in heme oxygenase-1 (HO-1) promoter and alcohol are related to the risk of esophageal squamous cell carcinoma on Chinese males.
Esophageal Squamous Cell Carcinoma
Upregulation of Ying Yang 1 (YY1) suppresses esophageal squamous cell carcinoma development through heme oxygenase-1.
Esophageal Squamous Cell Carcinoma
[The risk of esophageal squamous cell carcinoma associated with microsatellite polymorphism in promoter of heme oxygenase-1].
Esophagitis
Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine.
Esophagitis
Protective effect of Rhei Rhizoma on reflux esophagitis in rats via Nrf2-mediated inhibition of NF-?B signaling pathway.
Essential Hypertension
Association of an intronic variant of the heme oxygenase-1 gene with hypertension in northern Chinese Han population.
Essential Hypertension
Association of heme oxygenase-1 gene polymorphisms with essential hypertension and blood pressure in the Chinese Han population.
Essential Hypertension
Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension.
Essential Hypertension
The heme oxygenase system selectively suppresses the proinflammatory macrophage m1 phenotype and potentiates insulin signaling in spontaneously hypertensive rats.
Essential Tremor
Heme Oxygenase 1 and 2 Common Genetic Variants and Risk for Essential Tremor.
Fanconi Anemia
Impaired synthesis of heme oxygenase-1 in Fanconi anemia cells can be rescued by transfection of Fanconi wild-type cDNA.
Fatty Liver
Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis.
Fatty Liver
Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress.
Fatty Liver
Heme oxygenase-1 alleviates alcoholic liver steatosis: histopathological study.
Fatty Liver
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients.
Fatty Liver
Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice.
Fatty Liver
Heme oxygenase-1 protects against steatohepatitis both in cultured hepatocytes and in mice.
Fatty Liver
Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice.
Fatty Liver
Protective role of heme oxygenase-1 in fatty liver ischemia-reperfusion injury.
Fatty Liver
[Application of heme oxygenase 1 in the diagnosis of non-alcoholic fatty liver disease].
Fatty Liver, Alcoholic
The role of heme oxygenase-1 in drug metabolizing dysfunction in the alcoholic fatty liver exposed to ischemic injury.
Fetal Death
Exploring the potential of low doses carbon monoxide as therapy in pregnancy complications.
Fetal Death
Heme Oxygenase-1 Expression in the Ovary Dictates a Proper Oocyte Ovulation, Fertilization, and Corpora Lutea Maintenance.
Fetal Growth Retardation
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
Fetal Growth Retardation
Exploring the potential of low doses carbon monoxide as therapy in pregnancy complications.
Fetal Growth Retardation
Expression of endogenous heme oxygenase on surface of placental trophoblasts of pregnant women with intrauterine growth retardation of the fetus.
Fetal Growth Retardation
Haem oxygenase-1 dictates intrauterine fetal survival in mice via carbon monoxide.
Fetal Growth Retardation
Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction.
Fetal Growth Retardation
Heme oxygenase-1 is critically involved in placentation, spiral artery remodeling, and blood pressure regulation during murine pregnancy.
Fetal Growth Retardation
Maternal Heme Oxygenase 1 Regulates Placental Vasculature Development via Angiogenic Factors in Mice.
Fetal Growth Retardation
OS 21-05 PIVOTAL ROLE OF HEME OXYGENASE IN AMELIORATION BY NICOTINAMIDE OF FETAL GROWTH RESTRICTION ASSOCIATED WITH PREECLAMPSIA.
Fetal Growth Retardation
The Role of the Reduction of Spiral Artery Remodeling and Heme Oxygenase 1 in Mediating AT1-AA-Induced Hypertension and Intrauterine Growth Restriction in Pregnant Rats.
Fetal Growth Retardation
Using ultrasound to define the time point of intrauterine growth retardation in a mouse model of heme oxygenase-1 deficiency.
Fetal Resorption
Developmental role of nuclear factor E2-related factor 2 in mitigating methamphetamine fetal toxicity and postnatal neurodevelopmental deficits.
Fibrosarcoma
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells.
Fibrosarcoma
Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury from Oxidative Stress by Regulating Succinate, Lysophospholipid Metabolism, and ROS Scavenging System.
Fibrosarcoma
S-allyl cysteine activates the Nrf2-dependent antioxidant response and protects neurons against ischemic injury in vitro and in vivo.
Fibrosarcoma
[?-aminobutyric acid fortified rice alleviated oxidative stress and pancreatic injury in type 2 diabetic mice].
Frontotemporal Lobar Degeneration
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Gallstones
Activation of the Hypoxia Inducible Factor 1? Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.
Gallstones
Do UGT1A1 and HMOX1 gene promoter polymorphisms increase the risk of hyperbilirubinemia and gallstones in patients with hereditary spherocytosis?
Gastritis
Expression of heat shock protein 32 (hemoxygenase-1) in the normal and inflamed human stomach and colon: an immunohistochemical study.
Gastritis
The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms.
Gastrointestinal Diseases
Heme oxygenase-1: a novel therapeutic target for gastrointestinal diseases.
Gastrointestinal Diseases
Modulation of heme oxygenase in tissue injury and its implication in protection against gastrointestinal diseases.
Gastrointestinal Neoplasms
Importance of Heme Oxygenase-1 in Gastrointestinal Cancers: Functions, Inductions, Regulations, and Signaling.
Gastroparesis
CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice.
Gastroparesis
Diabetic Gastroparesis: An Emerging Role for Macrophages and Heme Oxygenase-1.
Gastroparesis
Effects of hemin on heme oxygenase-1, gastric emptying, and symptoms in diabetic gastroparesis.
Gastroparesis
Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis.
Gastroparesis
Idiopathic gastroparesis is associated with specific transcriptional changes in the gastric muscularis externa.
Gastroparesis
Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.
Glaucoma
Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease.
Glaucoma
Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage.
Glioblastoma
Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1.
Glioblastoma
Cytotoxic effects of metal protoporphyrins in glioblastoma cells: Roles of albumin, reactive oxygen species, and heme oxygenase-1.
Glioblastoma
Expression of heme oxygenase isozyme mRNAs in the human brain and induction of heme oxygenase-1 by nitric oxide donors.
Glioblastoma
Fenofibrate increases heme oxygenase 1 expression and astrocyte proliferation while limits neuronal injury during intracerebral hemorrhage.
Glioblastoma
Fenofibrate Increases Heme Oxygenase 1 Expression and Astrocyte Proliferation While Limits Neuronal Injury During Intracerebral Hemorrhage.
Glioblastoma
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells.
Glioblastoma
Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells.
Glioblastoma
Suppression of heme oxygenase-1 mRNA expression by interferon-gamma in human glioblastoma cells.
Glioblastoma
TGF?-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme.
Glioma
AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells.
Glioma
CD4+ CD25+ FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas.
Glioma
Cellular antioxidant adaptive survival response to 6-hydroxydopamine-induced nitrosative cell death in C6 glioma cells.
Glioma
Heme oxygenase (HO) isoforms in experimental C6 glioma: an immunocytochemical study.
Glioma
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells.
Glioma
Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma.
Glioma
Inhibition of heme oxygenase-1 enhances anti-cancer effects of arsenic trioxide on glioma cells.
Glioma
Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas.
Glioma
Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells.
Glioma
Possible Relation of Hemin-Induced HO-1 Expression to the Upregulation of VEGF and BDNF mRNA Levels in Rat C6 Glioma Cells.
Glioma
Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes.
Glioma
Spirulina non-protein components induce BDNF gene transcription via HO-1 activity in C6 glioma cells.
Glioma
The anti-tumor effects of calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas.
Glioma
The Correlation of Fluorescence of Protoporphyrinogen IX and Status of Isocitrate Dehydrogenase in Gliomas.
Glioma
Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter.
Glomerulonephritis
Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1.
Glomerulonephritis
Ferritin heavy chain mediates the protective effect of heme oxygenase-1 against oxidative stress.
Glomerulonephritis
Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury.
Glomerulonephritis
Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis.
Glomerulonephritis
Interactions between inducible nitric oxide synthase and heme oxygenase-1 in glomerulonephritis.
Glomerulonephritis
Mechanisms of HO-1 mediated attenuation of renal immune injury: a gene profiling study.
Glomerulonephritis
Regulatory effects of inducible nitric oxide synthase on cyclooxygenase-2 and heme oxygenase-1 expression in experimental glomerulonephritis.
Glomerulonephritis, IGA
Activated intrarenal reactive oxygen species and renin angiotensin system in IgA nephropathy.
Glomerulonephritis, IGA
The heme oxygenase-1 genotype is a risk factor to renal impairment of IgA nephropathy at diagnosis, which is a strong predictor of mortality.
Glomerulonephritis, Membranous
Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy.
Glomerulonephritis, Membranous
Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy.
Glucose Intolerance
Maternal serum heme-oxygenase-1 (HO-1) concentrations in early pregnancy and subsequent risk of gestational diabetes mellitus.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Risk assessment of gene variants for neonatal hyperbilirubinemia in Taiwan.
Glucosephosphate Dehydrogenase Deficiency
Risk assessment of gene variants for neonatal hyperbilirubinemia in Taiwan.
Graft vs Host Disease
Alleviation of graft-versus-host disease after conditioning with cobalt-protoporphyrin, an inducer of heme oxygenase-1.
Graft vs Host Disease
Donor-Derived Myeloid Heme Oxygenase-1 Controls the Development of Graft-Versus-Host Disease.
Graft vs Host Disease
High expression of heme oxygenase-1 in target organs may attenuate acute graft-versus-host disease through regulation of immune balance of TH17/Treg.
Graft vs Host Disease
Induction of heme oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation.
Granuloma
Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.
Granuloma
Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria.
Head Injuries, Closed
Zinc protoporphyrin IX attenuates closed head injury-induced edema formation, blood-brain barrier disruption, and serotonin levels in the rat.
Heart Arrest
Motor Cortex and Hippocampus Display Decreased Heme Oxygenase Activity 2 Weeks After Ventricular Fibrillation Cardiac Arrest in Rats.
Heart Diseases
The balance mediated by miRNAs and the heme oxygenase 1 feedback loop contributes to biological effects.
Heart Diseases
The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD.
Heart Failure
Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure.
Heart Failure
Chamber-specific regulation of heme oxygenase-1 (heat shock protein 32) in right-sided congestive heart failure.
Heart Failure
Fenofibrate Modulates HO-1 and Ameliorates Endothelial Expression of Cell Adhesion Molecules in Systolic Heart Failure.
Heart Failure
Functional heme oxygenase-1 promoter polymorphism in relation to heart failure and cardiac transplantation.
Heart Failure
Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung.
Heart Failure
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Heart Failure
Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Heart Failure
Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy.
Heart Failure
HO-1 induction improves the type-1 cardiorenal syndrome in mice with impaired angiotensin II-induced lymphocyte activation.
Heart Failure
Hydrogen sulfide upregulates heme oxygenase-1 expression in rats with volume overload-induced heart failure.
Heart Failure
Kappa-Opioid Agonist U50,488H-Mediated Protection Against Heart Failure Following Myocardial Ischemia/Reperfusion: Dual Roles of Heme Oxygenase-1.
Heart Failure
Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure.
Heart Failure
Modulation of the monocyte/macrophage system in heart failure by targeting heme oxygenase-1.
Heart Failure
Organic Nitrates in Heart Failure Revisited: Pentaerythritol Tetranitrate Induces Heme Oxygenase 1 to Protect the Myocardium.
Heart Failure
Protective effect of heme oxygenase-1 on Wistar rats with heart failure through the inhibition of inflammation and amelioration of intestinal microcirculation.
Hematologic Neoplasms
Overexpression of heme oxygenase-1 in bone marrow stromal cells promotes multiple myeloma resistance through the JAK2/STAT3 pathway.
Hematologic Neoplasms
Targeting of Hsp32 in solid tumors and leukemias: a novel approach to optimize anticancer therapy.
Hematologic Neoplasms
The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34(+)/CD38(+) and CD34(+)/CD38(-) AML progenitor cells.
heme oxygenase (biliverdin-producing) deficiency
Effect of Heme Oxygenase-1 Deficiency on Glomerular Proteomics.
heme oxygenase (biliverdin-producing) deficiency
Effect of heme oxygenase-1 deficiency on placental development.
heme oxygenase (biliverdin-producing) deficiency
Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice.
heme oxygenase (biliverdin-producing) deficiency
Heme Oxygenase-1 Deficiency and Oxidative Stress: A Review of 9 Independent Human Cases and Animal Models.
heme oxygenase (biliverdin-producing) deficiency
Heme Oxygenase-1 Deficiency Diminishes Methicillin-Resistant Staphylococcus aureus Clearance Due to Reduced TLR9 Expression in Pleural Mesothelial Cells.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency exacerbates angiotensin II-induced aortic aneurysm in mice.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency promotes severity of sepsis in a non-surgical preterm mouse model.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency results in splenic T-cell dysregulation in offspring of mothers exposed to late gestational inflammation.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-1 deficiency: the first autopsy case.
heme oxygenase (biliverdin-producing) deficiency
Heme Oxygenase-1 Influences Satellite Cells and Progression of Duchenne Muscular Dystrophy in Mice.
heme oxygenase (biliverdin-producing) deficiency
Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction.
heme oxygenase (biliverdin-producing) deficiency
Heme Oxygenases in Cardiovascular Health and Disease.
heme oxygenase (biliverdin-producing) deficiency
Heme, heme oxygenase and ferritin in vascular endothelial cell injury.
heme oxygenase (biliverdin-producing) deficiency
Hepatocellular heme oxygenase 1 deficiency does not affect inflammatory hepcidin regulation in mice.
heme oxygenase (biliverdin-producing) deficiency
Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency.
heme oxygenase (biliverdin-producing) deficiency
Human heme oxygenase-1 deficiency presenting with hemolysis, nephritis, and asplenia.
heme oxygenase (biliverdin-producing) deficiency
Human heme oxygenase-1 deficiency: a lesson on serendipity in the discovery of the novel disease.
heme oxygenase (biliverdin-producing) deficiency
Induction of Heme Oxygenase-1 Deficiency and Associated Glutamate-Mediated Neurotoxicity Is a Highly Conserved HIV Phenotype of Chronic Macrophage Infection That Is Resistant to Antiretroviral Therapy.
heme oxygenase (biliverdin-producing) deficiency
Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice.
heme oxygenase (biliverdin-producing) deficiency
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency.
heme oxygenase (biliverdin-producing) deficiency
Post-mortem Diagnosis of Heme Oxygenase-1 Deficiency by Whole Exome Sequencing in an Iranian Child.
heme oxygenase (biliverdin-producing) deficiency
Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation.
heme oxygenase (biliverdin-producing) deficiency
Sex-specific effects of heme oxygenase-2 deficiency on renovascular hypertension.
heme oxygenase (biliverdin-producing) deficiency
Splenic Ly6C(hi) monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice.
heme oxygenase (biliverdin-producing) deficiency
Structural evidence of genomic exon-deletion mediated by Alu-Alu recombination in a human case with heme oxygenase-1 deficiency.
heme oxygenase (biliverdin-producing) deficiency
The molecular basis of heme oxygenase deficiency in the pcd1 mutant of pea.
heme oxygenase (biliverdin-producing) deficiency
Tubular injury as a cardinal pathologic feature in human heme oxygenase-1 deficiency.
heme oxygenase (biliverdin-producing) deficiency
Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice.
Hemochromatosis
Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response.
Hemochromatosis
Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
Hemoglobinopathies
The Effect of ABO Blood Groups, Hemoglobinopathy, and Heme Oxygenase-1 Polymorphisms on Malaria Susceptibility and Severity.
Hemoglobinuria
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Hemophilia A
Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.
Hemorrhagic Fever, Ebola
Therapeutic potential of the heme oxygenase-1 inducer hemin against Ebola virus infection.
Hemorrhagic Stroke
Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells.
Hemorrhagic Stroke
Hematoma removal, heme, and heme oxygenase following hemorrhagic stroke.
Hemorrhagic Stroke
Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke.
Hemorrhagic Stroke
Neuroprotection after Hemorrhagic Stroke Depends on Cerebral Heme Oxygenase-1.
Hemorrhagic Stroke
Neuroprotective effects of valproic acid against hemin toxicity: Possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway.
Hemorrhagic Stroke
Transient elevation of serum bilirubin (a heme oxygenase-1 metabolite) level in hemorrhagic stroke: bilirubin is a marker of oxidant stress.
Hepatic Veno-Occlusive Disease
A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.
Hepatic Veno-Occlusive Disease
A Phosphodiesterase III Inhibitor Protects Rat Liver From Sinusoidal Obstruction Syndrome Through Heme Oxygenase-1 Induction.
Hepatitis
A high expression of heme oxygenase-1 in the liver of LEC rats at the stage of hepatoma: the possible implication of induction in uninvolved tissue.
Hepatitis
GT-Repeat Polymorphism in the HO-1 Gene Promoter Is Associated with Risk of Liver Cancer: A Follow-Up Study from Arseniasis-Endemic Areas in Taiwan.
Hepatitis
Resveratrol attenuates lipopolysaccharide-induced hepatitis in d-galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1.
Hepatitis
Transcriptional activation of heme oxygenase-1 and its functional significance in acetaminophen-induced hepatitis and hepatocellular injury in the rat.
Hepatitis
[Peculiarities of the Structural-Functional State of the Cytochrome Part of Liver Mitochondrial Respiratory Chain under Conditions of Acetaminophen-induced Hepatitis against the Background of Alimentary Deprivation of Protein].
Hepatitis B
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection.
Hepatitis B
Does Guasha Offer Hepatoprotective Effect to Chronic Inactive Hepatitis B Carriers? A Built-in Design to Control Subject Expectation.
Hepatitis B
Dynamic correlation between induction of the expression of heme oxygenase-1 and hepatitis B viral replication.
Hepatitis B
Hepatoprotective and antiviral properties of isochlorogenic acid A from Laggera alata against hepatitis B virus infection.
Hepatitis C
Beyond hepatitis C: The anti-inflammatory role of heme oxygenase-1 in systemic infections.
Hepatitis C
Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase?
Hepatitis C
Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells.
Hepatitis C
Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.
Hepatitis C
Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein.
Hepatitis C
Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury.
Hepatitis C
Hepatitis C core protein inhibits induction of heme oxygenase-1 and sensitizes hepatocytes to cytotoxicity.
Hepatitis C
Hypericin inhibits hepatitis C virus replication via deacetylation and down-regulation of heme oxygenase-1.
Hepatitis C
Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
Hepatitis C
Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV.
Hepatitis C
Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction.
Hepatitis C
MicroRNA-let-7c suppresses hepatitis C virus replication by targeting Bach1 for induction of heme oxygenase-1 expression.
Hepatitis C
Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes.
Hepatitis C
Reduced heme oxygenase-1 expression in steatotic livers infected with hepatitis C virus.
Hepatitis C
Restoration of Type I Interferon Expression by Heme and Related Tetrapyrroles Through Inhibition of NS3/4A Protease.
Hepatitis C
Ribavirin induced hemolysis: a novel mechanism of action against chronic hepatitis C virus infection.
Hepatitis C
Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway.
Hepatitis C
The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response.
Hepatitis C, Chronic
No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C.
Hepatitis, Alcoholic
Targeting heme oxygenase-1 by quercetin ameliorates alcohol-induced acute liver injury via inhibiting NLRP3 inflammasome activation.
Hepatitis, Animal
Guasha-induced hepatoprotection in chronic active hepatitis B: a case study.
Hepatitis, Chronic
Does Guasha Offer Hepatoprotective Effect to Chronic Inactive Hepatitis B Carriers? A Built-in Design to Control Subject Expectation.
Hepatitis, Chronic
[Study on heme oxygenase-1 and HAP model for the diagnosis of chronic hepatitis B-related liver fibrosis].
Hepatoblastoma
Heme Oxygenase-1 May Affect Cell Signalling via Modulation of Ganglioside Composition.
Hepatopulmonary Syndrome
Analysis of pulmonary heme oxygenase-1 and nitric oxide synthase alterations in experimental hepatopulmonary syndrome.
Hepatopulmonary Syndrome
Quercetin administration ameliorates pulmonary complications of cirrhosis in rats.
Hepatopulmonary Syndrome
Regulation of heme oxygenase-1 by nitric oxide during hepatopulmonary syndrome.
Hepatopulmonary Syndrome
The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat.
Hepatorenal Syndrome
Effect of heme oxygenase-1 on renal function in rats with liver cirrhosis.
Hernias, Diaphragmatic, Congenital
Expression of heme oxygenase-1 and endothelial nitric oxide synthase in the lung of newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension.
Herpes Simplex
Pharmacological Induction of Heme Oxygenase-1 Impairs Nuclear Accumulation of Herpes Simplex Virus Capsids upon Infection.
Herpes Zoster
Transcriptional responses in juvenile Atlantic cod (Gadus morhua) after exposure to mercury-contaminated sediments obtained near the wreck of the German WW2 submarine U-864, and from Bergen Harbor, Western Norway.
Hirschsprung Disease
An experimental study on the expression of heme oxygenase-2 mRNA in Hirschsprung's disease.
HIV Infections
Association of Genetic Polymorphisms of TGF-?1, HMOX1, and APOL1 With CKD in Nigerian Patients With and Without HIV.
HIV Infections
Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
HIV Infections
Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection.
HIV Infections
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Hodgkin Disease
Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase-1 through HIF-1?.
Huntington Disease
Alpha-7 nicotinic acetylcholine receptor agonist treatment in a rat model of Huntington's disease and involvement of heme oxygenase-1.
Hydrocephalus
Deferoxamine attenuates acute hydrocephalus after traumatic brain injury in rats.
Hydronephrosis
Urinary heme oxygenase-1 in children with congenital hydronephrosis due to ureteropelvic junction obstruction.
Hyperaldosteronism
Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension.
Hyperaldosteronism
The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension.
Hyperaldosteronism
Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism.
Hyperalgesia
H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
Hyperalgesia
The Anxiolytic and Antidepressant Effects of Diallyl Disulfide and GYY4137 in Animals with Chronic Neuropathic Pain.
Hyperalgesia
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Hyperalgesia
Treatment with 5-fluoro-2-oxindole Increases the Antinociceptive Effects of Morphine and Inhibits Neuropathic Pain.
Hyperalgesia
Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation.
Hyperalgesia
Wrapping With Basic Fibroblast Growth Factor-Impregnated Collagen Sheet Reduces Rat Sciatic Nerve Allodynia.
Hyperalgesia
[The role of HO/CO in the spinal nociception transmission and hyperalgesia of rats induced by formalin].
Hyperbilirubinemia, Neonatal
Association between genetic polymorphism of heme oxygenase 1 promoter and neonatal hyperbilirubinemia: a meta-analysis.
Hyperbilirubinemia, Neonatal
Association of HMOX1 gene promoter polymorphisms with hyperbilirubinemia in the early neonatal period.
Hyperbilirubinemia, Neonatal
Association of UGT1A1 variants and hyperbilirubinemia in breast-fed full-term Chinese infants.
Hyperbilirubinemia, Neonatal
Biochemical properties of the heme oxygenase inhibitor, Sn-protoporphyrin. Interactions with apomyoglobin and human serum albumin.
Hyperbilirubinemia, Neonatal
In vitro generation of carbon monoxide from organic molecules and synthetic metalloporphyrins mediated by light.
Hyperbilirubinemia, Neonatal
Interaction of hemopexin with Sn-protoporphyrin IX, an inhibitor of heme oxygenase. Role for hemopexin in hepatic uptake of Sn-protoporphyrin IX and induction of mRNA for heme oxygenase.
Hyperbilirubinemia, Neonatal
Neonatal hyperbilirubinemia in Japanese neonates: analysis of the heme oxygenase-1 gene and fetal hemoglobin composition in cord blood.
Hyperbilirubinemia, Neonatal
Tin-protoporphyrin-mediated disruption in vivo of heme oxygenase-2 protein integrity and activity in rat brain.
Hypercholesterolemia
Intravascular hemolysis increases atherogenicity of diet-induced hypercholesterolemia in rabbits in spite of heme oxygenase-1 gene and protein induction.
Hyperemia
Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures.
Hyperglycemia
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Hyperglycemia
Heme oxygenase overexpression attenuates glucose-mediated oxidative stress in quiescent cell phase: linking heme to hyperglycemia complications.
Hyperglycemia
Hyperglycemia in streptozotocin-induced diabetes leads to persistent inflammation and tissue damage following uveitis due to reduced levels of ciliary body heme oxygenase-1.
Hyperglycemia
Nrf2 Suppression Delays Diabetic Wound Healing Through Sustained Oxidative Stress and Inflammation.
Hyperglycemia
The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways.
Hyperglycemia
Transcriptomic Responses of Skeletal Muscle to Acute Exercise in Diabetic Goto-Kakizaki Rats.
Hyperglycemia
Tyrosol Facilitates Neovascularization by Enhancing Skeletal Muscle Cells Viability and Paracrine Function in Diabetic Hindlimb Ischemia Mice.
Hyperglycemia
Upregulation of the heme oxygenase system ameliorates postprandial and fasting hyperglycemia in type 2 diabetes.
Hyperhomocysteinemia
Hyperhomocysteinemia Accelerates Acute Kidney Injury to Chronic Kidney Disease Progression by Downregulating Heme Oxygenase-1 Expression.
Hyperhomocysteinemia
[Effects of plasma Hey on the contents of CO and HO-2 in the corpus cavernosum of ED rats with hyperhomocysteinemia].
Hyperlipidemias
[Effects of policosanol on serum lipids and heme oxygenase-1 in patients with hyperlipidemia].
Hypersensitivity
Heme oxygenase activity causes transient hypersensitivity to oxidative ultraviolet A radiation that depends on release of iron from heme.
Hypersensitivity
Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy.
Hypersensitivity
Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
Hypertension
Activation of heme oxygenase and suppression of cGMP are associated with impaired endothelial function in obstructive sleep apnea with hypertension.
Hypertension
Activation of PPAR-? ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21(WAF1): an in vivo study in rats.
Hypertension
Altered expression of the natriuretic peptide system in genetically modified heme oxygenase-1 mice treated with high dietary salt.
Hypertension
An analysis of the DOCA-salt model of hypertension in HO-1-/- mice and the Gunn rat.
Hypertension
Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta.
Hypertension
Association of an intronic variant of the heme oxygenase-1 gene with hypertension in northern Chinese Han population.
Hypertension
Calcitonin gene-related peptide, heme oxygenase-1, endothelial progenitor cells and nitric oxide-dependent vasodilation relationships in a human model of angiotensin II type-1 receptor antagonism.
Hypertension
Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension.
Hypertension
Effect of heme oxygenase 1 and renin/prorenin receptor on oxidized low-density lipoprotein-induced human umbilical vein endothelial cells.
Hypertension
Effect of olmesartan medoxomil on number and survival of circulating endothelial progenitor cells and calcitonin gene related peptide in hypertensive patients.
Hypertension
Erythropoietin Attenuates Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension through Interplay between Endothelial Progenitor Cells and Heme Oxygenase.
Hypertension
Expression of Heme Oxygenase-1 in Thick Ascending Loop of Henle Attenuates Angiotensin II-Dependent Hypertension.
Hypertension
Gene targeting and heme oxygenase-1 expression in prevention of hypertension induced by angiotensin II.
Hypertension
Heme arginate suppresses cardiac lesions and hypertrophy in deoxycorticosterone acetate-salt hypertension.
Hypertension
Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells.
Hypertension
Heme Oxygenase Improves Renal Function by Potentiating Podocyte-Associated Proteins in N ?-Nitro-l-Arginine-Methyl Ester (l-NAME)-Induced Hypertension.
Hypertension
Heme oxygenase induction attenuates TNF-?-induced hypertension in pregnant rodents.
Hypertension
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Hypertension
Heme oxygenase-1 alleviates vascular complications associated with metabolic syndrome: Effect on endothelial dependent relaxation and NO production.
Hypertension
Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils.
Hypertension
Heme oxygenase-1 induction does not improve vascular relaxation in angiotensin II hypertensive mice.
Hypertension
Heme oxygenase-1 induction protects against hypertension associated with diabetes: effect on exaggerated vascular contractility.
Hypertension
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Hypertension
Heme oxygenase-1 overexpression fails to attenuate hypertension when the nitric oxide synthase system is not fully operative.
Hypertension
Heme oxygenase-1 promotes migration and beta epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas.
Hypertension
Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans.
Hypertension
Heme-oxygenase upregulation ameliorates angiotensin II-induced tubulointerstitial injury and salt-sensitive hypertension.
Hypertension
Hippocampal neurogenesis response: What can we expect from two different models of hypertension?
Hypertension
HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice.
Hypertension
Increased HO-1 expression and decreased iNOS expression in the hippocampus from adult spontaneously hypertensive rats.
Hypertension
Induction of Heme Oxygenase 1 Attenuates Placental Ischemia-Induced Hypertension.
Hypertension
Induction of Heme Oxygenase-1 Attenuates sFlt-1-Induced Hypertension in Pregnant Rats.
Hypertension
Induction of heme oxygenase-1 shifts the balance from proinjury to prosurvival in the placentas of pregnant rats with reduced uterine perfusion pressure.
Hypertension
Interaction among heme oxygenase, nuclear factor-kappaB, and transcription activating factors in cardiac hypertrophy in hypertension.
Hypertension
Interaction between the heme oxygenase system and aldosterone in hypertension.
Hypertension
Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension.
Hypertension
Lentiviral-Human Heme Oxygenase Targeting Endothelium Improved Vascular Function In Ang II Animal Model of Hypertension.
Hypertension
Oxidative stress and post-transplant hypertension in pediatric kidney-transplanted patients.
Hypertension
Oxidative stress and TGFbeta in kidney-transplanted patients with cyclosporin-induced hypertension. Effect of carvedilol and nifedipine.
Hypertension
Renal Inhibition of Heme Oxygenase-1 Increases Blood Pressure in Angiotensin II-Dependent Hypertension.
Hypertension
Renal intramedullary infusion of tempol normalizes the blood pressure response to intrarenal blockade of heme oxygenase-1 in angiotensin II-dependent hypertension.
Hypertension
SIRT1, heme oxygenase-1 and NO-mediated vasodilation in a human model of endogenous angiotensin II type 1 receptor antagonism: implications for hypertension.
Hypertension
Study on the association between environmental cadmium exposure, cytochrome P450-mediated 20-HETE, heme-oxygenase-1 polymorphism and hypertension in Thai population residing in a malaria endemic areas with cadmium pollution.
Hypertension
The elevated blood pressure of human GRK4gamma A142V transgenic mice is not associated with increased ROS production.
Hypertension
The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats.
Hypertension
The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension.
Hypertension
The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude.
Hypertension
The Modulatory Role of Heme Oxygenase on Subpressor Angiotensin II-Induced Hypertension and Renal Injury.
Hypertension
The Role of the Reduction of Spiral Artery Remodeling and Heme Oxygenase 1 in Mediating AT1-AA-Induced Hypertension and Intrauterine Growth Restriction in Pregnant Rats.
Hypertension
Upregulation of Heme Oxygenase-1 in Response to Wild Thyme Treatment Protects against Hypertension and Oxidative Stress.
Hypertension
[Genistein attenuates monocrotaline-induced pulmonary arterial hypertension in rats by up-regulating heme oxygenase-1 expression].
Hypertension
[Hemeoxygenase expression and activity in human placenta of pregnancy induced hypertension]
Hypertension, Portal
Antioxidant role of heme oxygenase-1 in prehepatic portal hypertensive rats.
Hypertension, Portal
Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: A novel target for the attenuation of portal hypertension.
Hypertension, Portal
Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression.
Hypertension, Portal
Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats.
Hypertension, Portal
Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity.
Hypertension, Portal
Increased heme oxygenase-1 gene expression in the livers of patients with portal hypertension due to severe hepatic cirrhosis.
Hypertension, Portal
Pulmonary expression of iNOS and HO-1 protein is upregulated in a rat model of prehepatic portal hypertension.
Hypertension, Pregnancy-Induced
The pathogenetic role of heme in pregnancy-induced hypertension-like disease in ewes.
Hypertension, Pregnancy-Induced
[Hemeoxygenase expression and activity in human placenta of pregnancy induced hypertension]
Hypertension, Pregnancy-Induced
[Therapeutic effect of hemin on gestational hypertension in rats and the mechanism].
Hypertension, Pulmonary
Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells.
Hypertension, Pulmonary
Cardioprotective and vasomotor effects of HO activity during acute and chronic hypoxia.
Hypertension, Pulmonary
Effects of Salvia miltiorrhiza extracts on rat hypoxic pulmonary hypertension, heme oxygenase-1 and nitric oxide synthase.
Hypertension, Pulmonary
Expression of heme oxygenase-1 and endothelial nitric oxide synthase in the lung of newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension.
Hypertension, Pulmonary
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Hypertension, Pulmonary
Heme oxygenase-1 and inflammation in experimental right ventricular failure on prolonged overcirculation-induced pulmonary hypertension.
Hypertension, Pulmonary
Heme oxygenase-1 induces 15-lipoxygenase expression during hypoxia-induced pulmonary hypertension.
Hypertension, Pulmonary
Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension.
Hypertension, Pulmonary
Hepatic heme and drug metabolism in rats with chronic mountain sickness.
Hypertension, Pulmonary
Hypoxia inducible factor-1 alpha correlates the expression of heme oxygenase 1 gene in pulmonary arteries of rat with hypoxia-induced pulmonary hypertension.
Hypertension, Pulmonary
Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation.
Hypertension, Pulmonary
Increased pulmonary heme oxygenase-1 and delta-aminolevulinate synthase expression in monocrotaline-induced pulmonary hypertension.
Hypertension, Pulmonary
Loss of caveolin and heme oxygenase expression in severe pulmonary hypertension.
Hypertension, Pulmonary
Mesenchymal Stromal Cells Expressing Heme Oxygenase-1 Reverse Pulmonary Hypertension.
Hypertension, Pulmonary
Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat.
Hypertension, Pulmonary
Rapid clearance of circulating haptoglobin from plasma during acute pulmonary embolism in rats results in HMOX1 up-regulation in peripheral blood leukocytes.
Hypertension, Pulmonary
Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats.
Hypertension, Pulmonary
Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung.
Hypertension, Pulmonary
The role of endogenous carbon monoxide in the hypoxic vascular remodeling of rat model of hypoxic pulmonary hypertension.
Hypertension, Pulmonary
[The role of endogenous carbon monoxide in vascular remodeling in hypoxic pulmonary hypertension].
Hypertension, Renovascular
Increase in heme oxygenase-1 levels ameliorates renovascular hypertension.
Hypertension, Renovascular
Induction of heme oxygenase-1 in renovascular hypertension is associated with inhibition of apoptosis.
Hypertension, Renovascular
Sex-specific effects of heme oxygenase-2 deficiency on renovascular hypertension.
Hyperthyroidism
Heme Oxygenase-1 Prevents Hyperthyroidism Induced Hepatic Damage via an Antioxidant and Antiapoptotic Pathway.
Hypertriglyceridemia
Association of HMOX1 and NQO1 Polymorphisms with Metabolic Syndrome Components.
Hypertrophy, Left Ventricular
Upregulating the heme oxygenase system suppresses left ventricular hypertrophy in adult spontaneously hypertensive rats for 3 months.
Hypertrophy, Right Ventricular
Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation.
Hypoglycemia
Nrf2-mediated neuroprotection against recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes.
Hypotension
HSP induction inhibits iNOS mRNA expression and attenuates hypotension in endotoxin-challenged rats.
Hypoxia-Ischemia, Brain
Tin protoporphyrin provides protection following cerebral hypoxia-ischemia: involvement of alternative pathways.
IgA Vasculitis
Elevated serum heme oxygenase-1 and insulin-like growth factor-1 levels in patients with Henoch-Schonlein purpura.
Ileus
Hemin reduces postoperative ileus in a heme oxygenase 1-dependent manner while dimethyl fumarate does without heme oxygenase 1-induction.
Ileus
The role and interactions of nitric oxide (NO), carbon monoxide (CO), and prostanoids in the pathogenesis of postoperative ileus in rats.
Infarction, Middle Cerebral Artery
Cerebral heme oxygenase 1 and 2 spatial distribution is modulated following injury from hypoxia-ischemia and middle cerebral artery occlusion in rats.
Infarction, Middle Cerebral Artery
Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.
Infarction, Middle Cerebral Artery
Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice.
Infections
1H NMR characterization of the solution active site structure of substrate-bound, cyanide-inhibited heme oxygenase from Neisseria meningitidis: comparison to crystal structures.
Infections
A central role for free heme in the pathogenesis of severe malaria: the missing link?
Infections
Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells.
Infections
Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.
Infections
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Infections
Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinase- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis.
Infections
Beyond hepatitis C: The anti-inflammatory role of heme oxygenase-1 in systemic infections.
Infections
Bovine Herpesvirus 1 Productive Infection Led to Inactivation of Nrf2 Signaling through Diverse Approaches.
Infections
Classical swine fever virus induces oxidative stress in swine umbilical vein endothelial cells.
Infections
Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene.
Infections
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1.
Infections
Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells.
Infections
Emodin resists to Cyprinid herpesvirus 3 replication via the pathways of Nrf2/Keap1-ARE and NF-?B in the ornamental koi carp (Cyprinus carpio haematopterus).
Infections
Expression of heme oxygenase-1 is associated with abortion caused by Brucella abortus infection in pregnant mice.
Infections
Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate.
Infections
Factors involved in the depression of hepatic mixed function oxidase during infections with Listeria monocytogenes.
Infections
Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury.
Infections
Haeme oxygenase activity protects the host against excessive cardiac inflammation during experimental Trypanosoma cruzi infection.
Infections
Heat shock protein 32 in human peripheral blood mononuclear cells: effect of aging and inflammation.
Infections
Helicobacter pylori infection promotes autophagy through Nrf2-mediated heme oxygenase upregulation in human gastric cancer cells.
Infections
Heme arginate potentiates latent HIV-1 reactivation while inhibiting the acute infection.
Infections
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Infections
Heme dampens T-cell sequestration by modulating glial cell responses during rodent cerebral malaria.
Infections
Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella typhimurium infection.
Infections
Heme oxygenase 1 plays a crucial role in swamp eel response to oxidative stress induced by cadmium exposure or Aeromonas hydrophila infection.
Infections
Heme oxygenase limits Mycobacterium marinum infection-induced detrimental ferrostatin-sensitive cell death in zebrafish.
Infections
Heme oxygenase-1 activity is involved in the control of Toxoplasma gondii infection in the lung of BALB/c and C57BL/6 and in the small intestine of C57BL/6 mice.
Infections
Heme Oxygenase-1 and Carbon Monoxide Promote Burkholderia pseudomallei Infection.
Infections
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.
Infections
Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections.
Infections
Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages.
Infections
Heme oxygenase-1 inhibition promotes IFN?- and NOS2-mediated control of Mycobacterium tuberculosis infection.
Infections
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection.
Infections
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection.
Infections
Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria.
Infections
Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection.
Infections
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.
Infections
Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis.
Infections
Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon.
Infections
Hepatocarcinogenesis in hepatitis C: HCV shrewdly exacerbates oxidative stress by modulating both production and scavenging of reactive oxygen species.
Infections
Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa.
Infections
Induction of Heme Oxygenase-1 Deficiency and Associated Glutamate-Mediated Neurotoxicity Is a Highly Conserved HIV Phenotype of Chronic Macrophage Infection That Is Resistant to Antiretroviral Therapy.
Infections
Induction of heme oxygenase-1 increases infection of dog macrophages by L. infantum.
Infections
Infection of human endothelial cells with spotted Fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins.
Infections
Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease.
Infections
Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms.
Infections
Leishmania donovani Exploits Macrophage Heme Oxygenase-1 To Neutralize Oxidative Burst and TLR Signaling-Dependent Host Defense.
Infections
Leishmania pifanoi amastigotes avoid macrophage production of superoxide by inducing heme degradation.
Infections
miR-125b/NRF2/HO-1 axis is involved in protection against oxidative stress of cystic fibrosis: A pilot study.
Infections
miR-204/miR-211 downregulation contributes to Candidemia-induced kidney injuries via derepression of Hmx1 expression.
Infections
MiR-22 promotes porcine reproductive and respiratory syndrome virus replication by targeting the host factor HO-1.
Infections
Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens.
Infections
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection.
Infections
Novel Insights into the Regulatory Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 in Oxidative Stress and Inflammation of Human Fetal Membranes.
Infections
Pharmacological Induction of Heme Oxygenase-1 Impairs Nuclear Accumulation of Herpes Simplex Virus Capsids upon Infection.
Infections
Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes.
Infections
Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease.
Infections
PMA-triggered PKC? activity enhances Nrf2-mediated antiviral response on fish rhabdovirus infection.
Infections
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Infections
Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.
Infections
Respiratory syncytial virus inhibits ciliagenesis in differentiated normal human bronchial epithelial cells: effectiveness of N-acetylcysteine.
Infections
Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression.
Infections
Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
Infections
Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice.
Infections
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation.
Infections
Studies on heme and heme oxygenase during Plasmodium berghei infection in golden hamsters.
Infections
Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity.
Infections
The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium.
Infections
The effects of novel heme oxygenase inhibitors on the growth of Pseudomonas aeruginosa.
Infections
The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells.
Infertility, Male
Study of GT-repeat expansion in Heme oxygenase-1 gene promoter as genetic cause of male infertility.
Inflammatory Bowel Diseases
Association of the haem oxygenase-1 gene with inflammatory bowel disease.
Inflammatory Bowel Diseases
Dihydroartemisinin Regulates the Th/Treg Balance by Inducing Activated CD4+ T cell Apoptosis via Heme Oxygenase-1 Induction in Mouse Models of Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Expression of heat shock protein 32 (hemoxygenase-1) in the normal and inflamed human stomach and colon: an immunohistochemical study.
Inflammatory Bowel Diseases
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.
Inflammatory Bowel Diseases
Heme oxygenase-1: a new therapeutic target for inflammatory bowel disease.
Inflammatory Bowel Diseases
Increased intestinal luminal carbon monoxide gas in patients with ulcerative colitis.
Inflammatory Bowel Diseases
Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat.
Inflammatory Bowel Diseases
The role of heme oxygenase and carbon monoxide in inflammatory bowel disease.
Influenza in Birds
Down-regulation of cellular protein heme oxygenase-1 inhibits proliferation of avian influenza virus H9N2 in chicken oviduct epithelial cells.
Influenza, Human
Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice.
Influenza, Human
Chinese herbal medicine compound Yi-Zhi-Hao pellet inhibits replication of influenza virus infection through activation of heme oxygenase-1.
Influenza, Human
Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.
Influenza, Human
heme oxygenase-1 agonist CoPP suppresses influenza virus replication through IRF3-mediated generation of IFN-?/?.
Influenza, Human
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.
Influenza, Human
Practical strategies for targeting NF-kappaB and NADPH oxidase may improve survival during lethal influenza epidemics.
Insulin Resistance
Adipose overexpression of heme oxygenase-1 does not protect against high fat diet-induced insulin resistance in mice.
Insulin Resistance
Antiobesity effect of Biochanin-A: Effect on trace element metabolism in high fat diet-induced obesity in rats.
Insulin Resistance
ApoA1: Mimetic peptide reverses adipocyte dysfunction in vivo and in vitro via an increase in heme oxygenase (HO-1) and Wnt10b.
Insulin Resistance
Clinically confirmed DEL-1 as a myokine attenuates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes via AMPK/HO-1- pathway.
Insulin Resistance
Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids.
Insulin Resistance
Diminished upregulation of visceral adipose heme oxygenase-1 correlates with waist-to-hip ratio and insulin resistance.
Insulin Resistance
Expression levels of haem oxygenase-1 in the omental adipose tissue and peripheral blood mononuclear cells of women with polycystic ovary syndrome.
Insulin Resistance
Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes.
Insulin Resistance
Heme oxygenase-1 alleviates vascular complications associated with metabolic syndrome: Effect on endothelial dependent relaxation and NO production.
Insulin Resistance
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man.
Insulin Resistance
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats.
Insulin Resistance
Identification and validation of novel adipokines released from primary human adipocytes.
Insulin Resistance
Impact of Bariatric Surgery on Heme Oxygenase-1, Inflammation, and Insulin Resistance in Morbid Obesity with Obstructive Sleep Apnea.
Insulin Resistance
Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?
Insulin Resistance
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism.
Insulin Resistance
Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity.
Insulin Resistance
Myeloid heme oxygenase-1 haploinsufficiency reduces high fat diet-induced insulin resistance by affecting adipose macrophage infiltration in mice.
Insulin Resistance
The effect of a preparation of minerals, vitamins and trace elements on the cardiac gene expression pattern in male diabetic rats.
Insulin Resistance
The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension.
Insulin Resistance
Transcriptomic Responses of Skeletal Muscle to Acute Exercise in Diabetic Goto-Kakizaki Rats.
Insulin Resistance
Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance.
Insulin Resistance
Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive rats.
Insulin Resistance
Upregulating the heme oxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in rats.
Intervertebral Disc Degeneration
Heme oxygenase-1 attenuates IL-1? induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Intervertebral Disc Degeneration
Heme oxygenase-1 modulates degeneration of the intervertebral disc after puncture in Bach 1 deficient mice.
Intervertebral Disc Degeneration
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
Intervertebral Disc Degeneration
HO-1 induced autophagy protects against IL-1 ?-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-?B.
Intracranial Embolism
Carbon Monoxide and Iron Modulate Plasmatic Coagulation in Alzheimer's Disease.
Intracranial Hemorrhages
Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress-A New Insight into the Pathophysiology of Vascular Diseases.
Intussusception
Endogenous heme oxygenase/carbon monoxide system mediates lipopolysaccharide-induced intussusception in rats.
Iron Deficiencies
Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome.
Iron Deficiencies
Heme oxygenase: the physiological role of one of its metabolites, carbon monoxide and interactions with zinc protoporphyrin, cobalt protoporphyrin and other metalloporphyrins.
Iron Deficiencies
Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
Iron Deficiencies
Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine.
Iron Deficiencies
Zinc Protoporphyrin Upregulates Heme Oxygenase-1 in PC-3 Cells via the Stress Response Pathway.
Iron Overload
Control of delta-aminolaevulinate synthase and haem oxygenase in chronic-iron-overloaded rats.
Iron Overload
Dysfunction of the heme recycling system in heme oxygenase 1 deficient mice: effects on macrophage viability and tissue iron distribution.
Iron Overload
Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats.
Iron Overload
Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease.
Iron Overload
Heme metabolism and erythropoiesis in abnormal iron states: role of delta-aminolevulinic acid synthase and heme oxygenase.
Iron Overload
Heme oxygenase-1 protects bone marrow mesenchymal stem cells from iron overload through decreasing reactive oxygen species and promoting IL-10 generation.
Iron Overload
Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice.
Iron Overload
Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a ?-thalassemia mouse model.
Iron Overload
Iron overload upregulates haem oxygenase 1 in the lung more rapidly than in other tissues.
Iron Overload
Myelodysplastic syndrome macrophages have aberrant iron storage and heme oxygenase-1 expression.
Iron Overload
Oxidative stress-mediated down-regulation of rat hydroxyacid oxidase 1, a liver-specific peroxisomal enzyme.
Ischemic Attack, Transient
Activation of heme oxygenase-1 expression by disturbance of endoplasmic reticulum calcium homeostasis in rat neuronal cell culture.
Ischemic Attack, Transient
Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia.
Ischemic Attack, Transient
Sumoylation of hypoxia-inducible factor-1? ameliorates failure of brain stem cardiovascular regulation in experimental brain death.
Ischemic Stroke
A self-assembled DNA-nanoparticle with a targeting peptide for hypoxia-inducible gene therapy of ischemic stroke.
Ischemic Stroke
Delivery of Hypoxia-Inducible Heme Oxygenase-1 Gene for Site-Specific Gene Therapy in the Ischemic Stroke Animal Model.
Ischemic Stroke
Deoxycholic Acid-Conjugated Polyethylenimine for Delivery of Heme Oxygenase-1 Gene in Rat Ischemic Stroke Model.
Ischemic Stroke
Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection.
Ischemic Stroke
Heme Oxygenase 1-Mediated Neurogenesis Is Enhanced by Ginkgo biloba (EGb 761®) After Permanent Ischemic Stroke in Mice.
Ischemic Stroke
Induction of heme oxygenase-1 by traditional Chinese medicine formulation ISF-1 and its ingredients as a cytoprotective mechanism against oxidative stress.
Ischemic Stroke
Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature.
Ischemic Stroke
Nutraceutical induction and mimicry of heme oxygenase activity as a strategy for controlling excitotoxicity in brain trauma and ischemic stroke: focus on oxidative stress.
Ischemic Stroke
Rosmarinic acid elicits neuroprotection in ischemic stroke via Nrf2 and heme oxygenase 1 signaling.
Ischemic Stroke
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Ischemic Stroke
The potential role of HO-1 in regulating the MLK3-MKK7-JNK3 module scaffolded by JIP1 during cerebral ischemia/reperfusion in rats.
Ischemic Stroke
Up-regulation of heme oxygenase-1 protects against cold injury-induced brain damage: a laboratory-based study.
Jaundice, Neonatal
Absorption of zinc deuteroporphyrin IX 2,4-bis-glycol by the neonatal rat small intestine in vivo.
Jaundice, Neonatal
Duration of action and tissue distribution of zinc protoporphyrin in neonatal rats.
Jaundice, Neonatal
Expression and regulation of heme oxygenase isozymes in the developing mouse cortex.
Jaundice, Neonatal
New concepts in bilirubin and jaundice: report of the Third International Bilirubin Workshop, April 6-8, 1995, Trieste, Italy.
Jaundice, Neonatal
Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity.
Jaundice, Neonatal
Study of the developmental pattern of heme catabolism in liver and the effects of cobalt on cytochrome P-450 and the rate of heme oxidation during the neonatal period.
Jaundice, Neonatal
Systemic effects of orally-administered zinc and tin (IV) metalloporphyrins on heme oxygenase expression in mice.
Jaundice, Neonatal
The Role of Heme Oxygenase-1 Promoter Polymorphisms in Perinatal Disease.
Jaundice, Neonatal
Theoretical investigations on the hydrolysis pathway of tin verdoheme complexes: elucidation of tin's ring opening inhibition role.
Keratoconus
Investigation of Heme Oxygenase 2 Enzyme Protein Expression in Keratoconus and Normal Human Corneal Epithelium: An Immunohistochemical Study.
Kidney Diseases
BMP6 attenuates oxidant injury in HK-2 cells via Smad-dependent HO-1 induction.
Kidney Diseases
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Kidney Diseases
Induction of heme oxygenase-1 modulates the profibrotic effects of transforming growth factor-beta in human renal tubular epithelial cells.
Kidney Diseases
Length Polymorphism in Heme Oxygenase-1 and Risk of CKD among Patients with Coronary Artery Disease.
Kidney Diseases
Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling.
Kidney Diseases
Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models.
Kidney Diseases
Systematic review of the nuclear factor erythroid 2-related factor 2 (NRF2) system in human chronic kidney disease: alterations, interventions, and relation to morbidity.
Kidney Diseases, Cystic
Oxidant stress and reduced antioxidant enzyme protection in polycystic kidney disease.
Kidney Failure, Chronic
Effect of heme oxygenase-1 inducer hemin on chronic renal failure rats.
Kidney Failure, Chronic
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Kidney Failure, Chronic
Molecular biology-based assessment of vitamin e-coated dialyzer effects on oxidative stress, inflammation, and vascular remodeling.
Kidney Failure, Chronic
Skeletal muscle, cytokines, and oxidative stress in end-stage renal disease.
Kidney Failure, Chronic
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Kidney Failure, Chronic
[Changes of heme oxygenase-1 and inflammatory factors in patients with end-stage renal failure following hemodialysis]
Kidney Neoplasms
CXCR3-B can mediate growth-inhibitory signals in human renal cancer cells by downregulating the expression of heme oxygenase-1.
Kidney Neoplasms
Heme oxygenase-1 is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK Pathway, and mediates anti-apoptotic signal.
Kidney Neoplasms
Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules.
Kidney Neoplasms
Molecular pathways: Fumarate hydratase-deficient kidney cancer--targeting the Warburg effect in cancer.
Kidney Neoplasms
Novel Roles of c-Met in the Survival of Renal Cancer Cells through the Regulation of HO-1 and PD-L1 Expression.
Leishmaniasis, Visceral
Leishmania donovani Targets Host Transcription Factor NRF2 To Activate Antioxidant Enzyme HO-1 and Transcriptional Repressor ATF3 for Establishing Infection.
Leishmaniasis, Visceral
The effects of increased heme oxygenase-1 on the lymphoproliferative response in dogs with visceral leishmaniasis.
Leprosy, Tuberculoid
Indoleamine 2,3-dioxygenase and iron are required for Mycobacterium leprae survival.
Leukemia
Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.
Leukemia
Association between (GT)n Repeats in Heme Oxygenase-1 Gene Promoter and 3-Year Survival of Patients with Acute Leukemia: a Controlled, Cross-Sectional Study.
Leukemia
Contribution of the induction of heme oxygenase-1 to etoposide-induced apoptosis in acute myeloblastic leukemia.
Leukemia
Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators.
Leukemia
Expression of Heme Oxygenase-1 and Leukemia Inhibitory Factor in Maternal Plasma and Placental Tissue in a Lipopolysaccharide-Induced Late Pregnancy Preterm Birth Mouse Model.
Leukemia
Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells.
Leukemia
HO-1, RET and PML as possible markers for risk stratification of acute myelocytic leukemia and prognostic evaluation.
Leukemia
Identification of Heme Oxygenase-1 as a Novel Predictor of Hematopoietic Stem Cell Transplantation Outcomes in Acute Leukemia.
Leukemia
Induction of apoptosis in human leukemia cells through the production of reactive oxygen species and activation of HMOX1 and Noxa by benzene, toluene, and o-xylene.
Leukemia
Involvement of heme oxygenase-1 in kaempferol-induced anti-allergic actions in RBL-2H3 cells.
Leukemia
Nuclear translocation of heme oxygenase-1 confers resistance to Imatinib in chronic myeloid leukemia cells.
Leukemia
Redox Control of Leukemia: From Molecular Mechanisms to Therapeutic Opportunities.
Leukemia
Regulatory T cells induce a privileged tolerant microenvironment at the fetal-maternal interface.
Leukemia
Targeting of Hsp32 in solid tumors and leukemias: a novel approach to optimize anticancer therapy.
Leukemia
The Landscape of Gene Expression and Molecular Regulation Following Spinal Cord Hemisection in Rats.
Leukemia
The role of nrf2 and cytoprotection in regulating chemotherapy resistance of human leukemia cells.
Leukemia
Upregulation of heme oxygenase-1 by degranulation in rat basophilic leukemia cells.
Leukemia
VLX1570 induces apoptosis through the generation of ROS and induction of ER stress on leukemia cell lines.
Leukemia, Erythroblastic, Acute
Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines. A possible strategy for the maintenance of intracellular heme level.
Leukemia, Lymphocytic, Chronic, B-Cell
Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Heme oxygenase-1 contributes to imatinib resistance by promoting autophagy in chronic myeloid leukemia through disrupting the mTOR signaling pathway.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Heme oxygenase-1 reduces the sensitivity to imatinib through nonselective activation of histone deacetylases in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Identification of heme oxygenase-1 as a novel BCR/ABL-dependent survival factor in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Induction of heme oxygenase-1 by Na+-H+ exchanger 1 protein plays a crucial role in imatinib-resistant chronic myeloid leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Nuclear translocation of heme oxygenase-1 confers resistance to Imatinib in chronic myeloid leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Over-expression of heme oxygenase-1 in peripheral blood predicts the progression and relapse risk of chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Overexpression of heme oxygenase-1 in bone marrow stromal cells promotes microenvironment-mediated imatinib resistance in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Translocation of heme oxygenase-1 contributes to imatinib resistance in chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[CML Cell Apotosis Induced by AMN107 Combined with Heme Oxygenase-1 Inhibitor].
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effects of HO-1 gene expression on proliferation of imatinib resistant CML cells].
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[The effect of retrovirus-mediated HO-1 gene on chronic myeloid leukemia resistance cell K562/A02 apoptosis induced by nilotinib].
Leukemia, Myeloid
CD64-targeted HO-1 RNA interference enhances chemosensitivity in orthotopic model of acute myeloid leukemia and patient-derived bone marrow cells.
Leukemia, Myeloid
Modification by heme oxygenase inhibitor, tin protoporphyrin, of cellular differentiation of human myeloid leukemia K562 cell line.
Leukemia, Myeloid
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses.
Leukemia, Myeloid, Acute
Contribution of the induction of heme oxygenase-1 to etoposide-induced apoptosis in acute myeloblastic leukemia.
Leukemia, Myeloid, Acute
Crucial role of heme oxygenase-1 in the sensitivity of acute myeloid leukemia cell line Kasumi-1 to ursolic acid.
Leukemia, Myeloid, Acute
Heme Oxygenase 1-Targeted Hybrid Nanoparticle for Chemo- and Immuno-Combination Therapy in Acute Myelogenous Leukemia.
Leukemia, Myeloid, Acute
Heme oxygenase-1 plays a crucial role in chemoresistance in acute myeloid leukemia.
Leukemia, Myeloid, Acute
Heme oxygenase-1 suppresses the apoptosis of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway.
Leukemia, Myeloid, Acute
Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia.
Leukemia, Myeloid, Acute
In vivo and in vitro effects of heme oxygenase-1 silencing on the survival of acute myelocytic leukemia-M2 cells.
Leukemia, Myeloid, Acute
Maesopsin 4-O-beta-D-glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia.
Leukemia, Myeloid, Acute
NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction.
Leukemia, Myeloid, Acute
Proapoptotic effects of heme oxygenase-1 inhibitor on Kasumi-1 cells via the ATF4/CHOP/Ire-1? pathway.
Leukemia, Myeloid, Acute
Silencing HO-1 sensitizes SKM-1 cells to apoptosis induced by low concentration 5-azacytidine through enhancing p16 demethylation.
Leukemia, Myeloid, Acute
The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?
Leukemia, Myeloid, Acute
The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34(+)/CD38(+) and CD34(+)/CD38(-) AML progenitor cells.
Lewy Body Disease
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Liver Cirrhosis
Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis.
Liver Cirrhosis
Effects of heme oxygenase-1 on pulmonary function and structure in rats with liver cirrhosis.
Liver Cirrhosis
GT-Repeat Polymorphism in the HO-1 Gene Promoter Is Associated with Risk of Liver Cancer: A Follow-Up Study from Arseniasis-Endemic Areas in Taiwan.
Liver Cirrhosis
Heme oxygenase-1 exerts pro-apoptotic effects on hepatic stellate cells in vitro through regulation of nuclear factor-?B.
Liver Cirrhosis
Heme oxygenase-1 prevents liver fibrosis in rats by regulating the expression of PPAR? and NF-?B.
Liver Cirrhosis
Heme oxygenase-1 regulates the major route involved in formation of immune hepatic fibrosis in rats.
Liver Cirrhosis
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Liver Cirrhosis
Increased heme oxygenase-1 gene expression in the livers of patients with portal hypertension due to severe hepatic cirrhosis.
Liver Cirrhosis
Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice.
Liver Cirrhosis
Influence of heme oxygenase-1 expression on immune liver fibrosis induced by cobalt protoporphyrin in rats.
Liver Cirrhosis
Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation.
Liver Cirrhosis
Nitric oxide synthase and heme oxygenase expressions in human liver cirrhosis.
Liver Cirrhosis
Octreotide attenuates liver fibrosis by inhibiting hepatic heme oxygenase-1 expression.
Liver Cirrhosis
Quercetin administration ameliorates pulmonary complications of cirrhosis in rats.
Liver Cirrhosis
rAAV-mediated stable expression of heme oxygenase-1 in stellate cells: a new approach to attenuate liver fibrosis in rats.
Liver Cirrhosis
Role of the heme oxygenase/carbon monoxide pathway in the pathogenesis and prevention of hepatic encephalopathy.
Liver Cirrhosis
[Expression and location of heme oxygenase in the lung of experimental cirrhotic rats]
Liver Cirrhosis
[Study on heme oxygenase-1 and HAP model for the diagnosis of chronic hepatitis B-related liver fibrosis].
Liver Diseases
Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress.
Liver Diseases
Heme oxygenase-1 gene promoter polymorphism and the risk of pediatric nonalcoholic fatty liver disease.
Liver Diseases
Heme Oxygenase-1 Induction by Cobalt Protoporphyrin Ameliorates Cholestatic Liver Disease in a Xenobiotic-Induced Murine Model.
Liver Diseases
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients.
Liver Diseases
Heme oxygenase-1 mRNA expression in egyptian patients with chronic liver disease.
Liver Diseases
Heme Oxygenase-1 Prevents Hyperthyroidism Induced Hepatic Damage via an Antioxidant and Antiapoptotic Pathway.
Liver Diseases
Heme oxygenase-1 regulates the major route involved in formation of immune hepatic fibrosis in rats.
Liver Diseases
Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury.
Liver Diseases
Inhibition of heme oxygenase ameliorates sepsis-induced liver dysfunction in rats.
Liver Diseases
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Liver Diseases
Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease.
Liver Diseases
SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Liver Diseases
Tissue lipid peroxidation may be triggered by increased formation of bilirubin in vivo.
Liver Diseases
Transduced PEP-1-Heme Oxygenase-1 Fusion Protein Attenuates Lung Injury in Septic Shock Rats.
Liver Diseases, Alcoholic
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is not associated with alcoholic liver disease severity.
Liver Diseases, Alcoholic
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is not associated with alcoholic liver disease severity: Reply.
Liver Diseases, Alcoholic
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Liver Failure
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.
Liver Failure
Heme oxygenase-1 alleviates mouse hepatic failure through suppression of adaptive immune responses.
Liver Failure
Inhibition of dendritic cell maturation and function is independent of heme oxygenase 1 but requires the activation of STAT3.
Liver Failure
The significance of the peroxides increase in the plasma of the patients with liver failure.
Liver Failure, Acute
Increased heme oxygenase-1 and decreased delta-aminolevulinate synthase expression in the liver of patients with acute liver failure.
Liver Failure, Acute
Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure.
Liver Failure, Acute
Mesenchymal stem cells increase heme oxygenase 1-activated autophagy in treatment of acute liver failure.
Liver Failure, Acute
NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1.
Liver Failure, Acute
Protective effects of protostemonine on LPS/GalN-induced acute liver failure: Roles of increased hepatic expression of heme oxygenase-1.
Liver Failure, Acute
Resveratrol attenuates lipopolysaccharide-induced hepatitis in d-galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1.
Liver Neoplasms
GT-Repeat Polymorphism in the HO-1 Gene Promoter Is Associated with Risk of Liver Cancer: A Follow-Up Study from Arseniasis-Endemic Areas in Taiwan.
Liver Neoplasms
Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis.
Liver Neoplasms
Transcriptome analysis of PPAR? target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.
Lung Diseases
Expression of heme oxygenase-1 in type II pneumocytes protects against heatstroke-induced lung damage.
Lung Diseases
Heme oxygenase attenuates allergen-induced airway inflammation and hyperreactivity in guinea pigs.
Lung Diseases
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system.
Lung Diseases, Interstitial
Decreased expression of haem oxygenase-1 by alveolar macrophages in idiopathic pulmonary fibrosis.
Lung Diseases, Interstitial
Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.
Lung Diseases, Interstitial
Heme Oxygenase-1 in Patients With Interstitial Lung Disease: A Review of the Clinical Evidence.
Lung Diseases, Interstitial
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system.
Lung Diseases, Interstitial
Serum heme oxygenase-1 measurement is useful for evaluating disease activity and outcomes in patients with acute respiratory distress syndrome and acute exacerbation of interstitial lung disease.
Lung Diseases, Obstructive
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system.
Lung Injury
Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice.
Lung Injury
Andrographolide protects against cigarette smoke-induced lung inflammation through activation of heme oxygenase-1.
Lung Injury
Anti-apoptosis effect of heme oxygenase-1 on lung injury after cardiopulmonary bypass.
Lung Injury
Anti-inflammatory effects of mangiferin on sepsis-induced lung injury in mice via up-regulation of heme oxygenase-1.
Lung Injury
Artesunate Protects Against Sepsis-Induced Lung Injury Via Heme Oxygenase-1 Modulation.
Lung Injury
Attenuation of TGF-ss-Stimulated Collagen Production in Fibroblasts by Quercetin-Induced HO-1.
Lung Injury
Biliverdin administration protects against endotoxin-induced acute lung injury in rats.
Lung Injury
BML-111, a lipoxin receptor agonist, ameliorates 'two-hit'-induced acute pancreatitis-associated lung injury in mice by the upregulation of heme oxygenase-1.
Lung Injury
BMP4 Induces HO-1 via a Smad-Independent, p38MAPK-Dependent Pathway in Pulmonary Artery Myocytes.
Lung Injury
Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease.
Lung Injury
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.
Lung Injury
Cardiopulmonary, Histologic, and Inflammatory Effects of Intravenous Na2S After Blunt Chest Trauma-Induced Lung Contusion in Mice.
Lung Injury
Change of heme oxygenase-1 expression in lung injury induced by chrysotile asbestos in vivo and in vitro.
Lung Injury
Curcumin Attenuates Cardiopulmonary Bypass-Induced Lung Oxidative Damage in Rats.
Lung Injury
Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1.
Lung Injury
Desoxyrhapontigenin up-regulates Nrf2-mediated heme oxygenase-1 expression in macrophages and inflammatory lung injury.
Lung Injury
Dexmedetomidine attenuates oxidative/nitrative stress in lung tissues of septic mice partly via activating heme oxygenase-1.
Lung Injury
Eff ects of hemin, a heme oxygenase-1 inducer in L-arginine-induced acute pancreatitis and associated lung injury in adult male albino rats.
Lung Injury
Endogenous carbon monoxide attenuates lung injury following ischemia-reperfusion in the hind limbs of rats.
Lung Injury
Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury.
Lung Injury
Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model.
Lung Injury
Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury.
Lung Injury
Heme Oxygenase-1 Mediates the Protective Effects of Ischemic Preconditioning on Mitigating Lung Injury Induced by Lower Limb Ischemia-Reperfusion in Rats.
Lung Injury
Heme oxygenase-1 modulates thrombomodulin and activated protein c levels to attenuate lung injury in cecal ligation and puncture-induced acute lung injury mice.
Lung Injury
Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of ?-catenin/hnRNPK signaling.
Lung Injury
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.
Lung Injury
Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury.
Lung Injury
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury.
Lung Injury
Hydrogen gas inhibits high-mobility group box 1 release in septic mice by upregulation of heme oxygenase 1.
Lung Injury
Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
Lung Injury
Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups
Lung Injury
Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups.
Lung Injury
Ischemia/reperfusion Lung Injury Increases Serum Ferritin and Heme Oxygenase-1 in Rats.
Lung Injury
Ischemic post-conditioning attenuates acute lung injury induced by intestinal ischemia-reperfusion in mice: role of Nrf2.
Lung Injury
Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1.
Lung Injury
Naringin Decreases TNF-? and HMGB1 Release from LPS-Stimulated Macrophages and Improves Survival in a CLP-Induced Sepsis Mice.
Lung Injury
Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock.
Lung Injury
Protective effect of heme oxygenase-1 on lung injury induced by erythrocyte instillation in rats.
Lung Injury
Protective effect of hypercapnic acidosis in ischemia-reperfusion lung injury is attributable to upregulation of heme oxygenase-1.
Lung Injury
Protective effects of HO-1 pathway on lung injury subsequent to limb ischemia reperfusion.
Lung Injury
Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury.
Lung Injury
Role of heme oxygenase in pulmonary response to antigen challenge in sensitized rats in vivo.
Lung Injury
Role of HO-1 in protective effect of electro-acupuncture against endotoxin shock-induced acute lung injury in rabbits.
Lung Injury
Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide.
Lung Injury
Systemic perfluorohexane attenuates lung injury induced by lipopolysaccharide in rats: the role of heme oxygenase-1.
Lung Injury
Valproic Acid Attenuates Acute Lung Injury Induced by Ischemia-Reperfusion in Rats.
Lung Injury
Wood smoke extract promotes both apoptosis and proliferation in rat alveolar epithelial type II cells: the role of oxidative stress and heme oxygenase-1.
Lung Injury
[A study of the role of heme oxygenase-1 expression in ventilator induced lung injury and its mechanism in rats]
Lung Injury
[Effect of baicalin on expression of heme oxygenase-1 in lung injury of rats associated with paraquat poisoning]
Lung Injury
[Effect of hydrogen-saline on lung injury and heme oxygenase-1 expression in the lung tissue of acute paraquat-intoxicated mice].
Lung Injury
[Expression of heme oxygenase-1 and inducible nitric oxide synthase in the lungs of hyperoxia-exposed preterm rats].
Lung Injury
[Protective effects of the induction of heme oxygenase-1 on ischemia reperfusion lung injury: in vivo experiment with rats]
Lung Injury
[Research on the effect of protection against ventilator-induced lung injury via regulation of caveolin-1/heme oxygenase-1 signaling].
Lung Injury
[The role of heme oxygenase-1 in the protection of chronic intermittent hypoxia-induced lung injury in vivo].
Lung Neoplasms
Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.
Lung Neoplasms
Effects of dexmedetomidine pretreatment on heme oxygenase-1 expression and oxidative stress during one-lung ventilation.
Lung Neoplasms
Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data.
Lung Neoplasms
High expression of heme oxygenase-1 is associated with tumor invasiveness and poor clinical outcome in non-small cell lung cancer patients.
Lung Neoplasms
Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice.
Lung Neoplasms
Inhibition of heme oxygenase-1 enhances the radiosensitivity in human nonsmall cell lung cancer a549 cells.
Lung Neoplasms
Inhibition of heme oxygenase-1 with an epidermal growth factor receptor inhibitor and cisplatin decreases proliferation of lung cancer A549 cells.
Lung Neoplasms
KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells.
Lung Neoplasms
Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.
Lung Neoplasms
MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1.
Lung Neoplasms
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation.
Lung Neoplasms
Propyl gallate sensitizes human lung cancer cells to cisplatin-induced apoptosis by targeting heme oxygenase-1 for TRC8-mediated degradation.
Lung Neoplasms
Smad7 sensitizes A549 lung cancer cells to cisplatin-induced apoptosis through heme oxygenase-1 inhibition.
Lung Neoplasms
Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin.
Lung Neoplasms
Targeting Nrf2-mediated heme oxygenase-1 enhances non-thermal plasma-induced cell death in non-small-cell lung cancer A549 cells.
Lung Neoplasms
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Lung Neoplasms
Tin Mesoporphyrin Selectively Reduces Non-Small-Cell Lung Cancer Cell Line A549 Proliferation by Interfering with Heme Oxygenase and Glutathione Systems.
Lupus Erythematosus, Systemic
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
HMOX1 promoter (GT)n polymorphim is associated with childhood-onset systemic lupus erythematosus but not with juvenile rheumatoid arthritis in a Mexican population.
Lymphatic Metastasis
Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis.
Lymphatic Metastasis
Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas.
Lymphoma
Ablation of the tumor suppressor histidine triad nucleotide binding protein 1 is protective against hepatic ischemia/reperfusion injury.
Lymphoma
Attenuation of High Glucose-Induced Rat Cardiomyocyte Apoptosis by Exendin-4 via Intervention of HO-1/Nrf-2 and the PI3K/AKT Signaling Pathway.
Lymphoma
Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-?B-Controlled Oxidative Stress Responses.
Lymphoma
Chi-Ju-Di-Huang-Wan protects rats against retinal ischemia by downregulating matrix metalloproteinase-9 and inhibiting p38 mitogen-activated protein kinase.
Lymphoma
Cobalt-protoporphyrin enhances heme oxygenase 1 expression and attenuates liver ischemia/reperfusion injury by inhibiting apoptosis.
Lymphoma
Cytoprotective pathways in the vascular endothelium. Do they represent a viable therapeutic target?
Lymphoma
Identification of a cis-acting element responsive to ultrasound in the 5'-flanking region of the human heme oxygenase-1 gene.
Lymphoma
Losartan improves erectile function through suppression of corporal apoptosis and oxidative stress in rats with cavernous nerve injury.
Lymphoma
N-acetylcysteine protects ovarian follicles from ischemia-reperfusion injury in xenotransplanted human ovarian tissue.
Lymphoma
Ocular Effects of Sildenafil in Naïve Mice and a Mouse Model of Optic Nerve Crush.
Lymphoma
Resveratrol Attenuates Doxorubicin-Induced Cardiomyocyte Apoptosis in Lymphoma Nude Mice by Heme Oxygenase-1 Induction.
Lymphoma
Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells.
Lymphoma
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development.
Lymphoma
Smokeless tobacco extract inhibits proliferation and promotes apoptosis in oral mucous fibroblasts.
Lymphoma, B-Cell
Ablation of the tumor suppressor histidine triad nucleotide binding protein 1 is protective against hepatic ischemia/reperfusion injury.
Lymphoma, B-Cell
Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury.
Lymphoma, B-Cell
Ameliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway.
Lymphoma, B-Cell
Argon Mitigates Impaired Wound Healing Process and Enhances Wound Healing In Vitro and In Vivo.
Lymphoma, B-Cell
Chi-Ju-Di-Huang-Wan protects rats against retinal ischemia by downregulating matrix metalloproteinase-9 and inhibiting p38 mitogen-activated protein kinase.
Lymphoma, B-Cell
Cytoprotective pathways in the vascular endothelium. Do they represent a viable therapeutic target?
Lymphoma, B-Cell
Development of an alternative zebrafish model for drug-induced intestinal toxicity.
Lymphoma, B-Cell
Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.
Lymphoma, B-Cell
Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats.
Lymphoma, B-Cell
Effect of human umbilical cord blood mesenchymal stem cells administered by intravenous or intravitreal routes on cryo-induced retinal injury.
Lymphoma, B-Cell
Effect of levocarnitine on cerebral ischemia-reperfusion rats via activating Nrf2/ARE signaling pathway.
Lymphoma, B-Cell
Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-?B signaling pathway.
Lymphoma, B-Cell
l-Arginine Protects Ovine Intestinal Epithelial Cells from Lipopolysaccharide-Induced Apoptosis through Alleviating Oxidative Stress.
Lymphoma, B-Cell
Mycophenolate mofetil attenuates concanavalin A-induced acute liver injury through modulation of TLR4/NF-?B and Nrf2/HO-1 pathways.
Lymphoma, B-Cell
Neuroprotective Effect of 4-Phenylbutyric Acid against Photo-Stress in the Retina.
Lymphoma, B-Cell
Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO-1/NF-?B signaling pathway.
Lymphoma, B-Cell
Overexpression of heme oxygenase-1 induced by constitutively activated NF-?B as a potential therapeutic target for activated B-cell-like diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Preventive Effect of Lactobacillus fermentum CQPC08 on 4-Nitroquineline-1-Oxide Induced Tongue Cancer in C57BL/6 Mice.
Lymphoma, B-Cell
Protective effect of artemisia asiatica extract against renal ischemia-reperfusion injury in mice.
Lymphoma, B-Cell
Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor
Lymphoma, B-Cell
Steroidal Saponin Diosgenin from Dioscorea bulbifera Protects Cardiac Cells from Hypoxia-reoxygenation Injury Through Modulation of Pro-survival and Pro-death Molecules.
Lymphoma, B-Cell
The Coffee Diterpene, Kahweol, Ameliorates Pancreatic ?-Cell Function in Streptozotocin (STZ)-Treated Rat INS-1 Cells through NF-kB and p-AKT/Bcl-2 Pathways.
Lymphoma, B-Cell
Transcriptional Changes after Enniatins A, A1, B and B1 Ingestion in Rat Stomach, Liver, Kidney and Lower Intestine.
Lymphoma, Large B-Cell, Diffuse
Overexpression of heme oxygenase-1 induced by constitutively activated NF-?B as a potential therapeutic target for activated B-cell-like diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor
Lymphoproliferative Disorders
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Lymphoproliferative Disorders
Human spleen heme oxygenase in normal, hemolytic and other pathological states.
Macrophage Activation Syndrome
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Macular Degeneration
An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration.
Macular Degeneration
Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration.
Macular Degeneration
Lack of association between the c.544G>A polymorphism of the heme oxygenase-2 gene and age-related macular degeneration.
Malaria
A central role for free heme in the pathogenesis of severe malaria: the missing link?
Malaria
Association of heme oxygenase 1 with the restoration of liver function after damage in murine malaria by Plasmodium yoelii.
Malaria
Could Heme Oxygenase-1 Be a New Target for Therapeutic Intervention in Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome?
Malaria
Heme oxygenase and related indices in chloroquine-resistant and -sensitive strains of Plasmodium berghei.
Malaria
HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.
Malaria
HO-1 polymorphism as a genetic determinant behind the malaria resistance afforded by haemolytic disorders.
Malaria
Increased carboxyhemoglobin in adult falciparum malaria is associated with disease severity and mortality.
Malaria
Malaria parasite-mediated alteration of macrophage function and increased iron availability predispose to disseminated non-typhoidal Salmonella infection.
Malaria
Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children.
Malaria
Potential inhibitors of plasmodial heme oxygenase; an innovative approach for combating chloroquine resistant malaria.
Malaria
Prolonged neutrophil dysfunction after Plasmodium falciparum malaria is related to hemolysis and heme oxygenase-1 induction.
Malaria
Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity.
Malaria
The association between Haptoglobin and Heme Oxygenase-1 genetic profiles and sCD163 in the susceptibility to and severity of human malaria.
Malaria
The Effect of ABO Blood Groups, Hemoglobinopathy, and Heme Oxygenase-1 Polymorphisms on Malaria Susceptibility and Severity.
Malaria
Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.
Malaria, Cerebral
Could Heme Oxygenase-1 Be a New Target for Therapeutic Intervention in Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome?
Malaria, Cerebral
Glutathione peroxidase contributes with heme oxygenase-1 to redox balance in mouse brain during the course of cerebral malaria.
Malaria, Cerebral
Heme dampens T-cell sequestration by modulating glial cell responses during rodent cerebral malaria.
Malaria, Cerebral
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria.
Malaria, Cerebral
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to cerebral malaria in Myanmar.
Malaria, Cerebral
Possible role of heme oxygenase-1 and prostaglandins in the pathogenesis of cerebral malaria: heme oxygenase-1 induction by prostaglandin D(2) and metabolite by a human astrocyte cell line.
Malaria, Cerebral
Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.
Malaria, Falciparum
Prolonged neutrophil dysfunction after Plasmodium falciparum malaria is related to hemolysis and heme oxygenase-1 induction.
Malnutrition
Chemical pathology of homocysteine. V. Thioretinamide, thioretinaco, and cystathionine synthase function in degenerative diseases.
Massive Hepatic Necrosis
Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.
Mastocytoma
Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis.
Measles
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Medulloblastoma
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition.
Melanoma
A microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with risk for melanoma.
Melanoma
Co-expression of thymidine phosphorylase and heme oxygenase-1 in macrophages in human malignant vertical growth melanomas.
Melanoma
Combination of PDT and inhibitor treatment affects melanoma cells and spares keratinocytes.
Melanoma
Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma.
Melanoma
Decreased heme oxygenase-1 expression distinguishes human melanomas from melanocytic nevi.
Melanoma
Deuterium Oxide (D2O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma.
Melanoma
Effect of Heme Oxygenase-1 on Melanoma Development in Mice-Role of Tumor-Infiltrating Immune Cells.
Melanoma
Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy.
Melanoma
Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma.
Melanoma
Hsps are up-regulated in melanoma tissue and correlate with patient clinical parameters.
Melanoma
Inhibition of heme oxygenase-1 increases responsiveness of melanoma cells to ALA-based photodynamic therapy.
Melanoma
Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice.
Melanoma
Oxidized Lipoproteins Promote Resistance to Cancer Immunotherapy Independent of Patient Obesity.
Melanoma
Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors.
Melanoma
Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy.
Melanoma
Relationships between thermotolerance, oxidative stress responses and induction of stress proteins in human tumour cell lines.
Melanoma
The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1.
Melioidosis
Heme Oxygenase-1 and Carbon Monoxide Promote Burkholderia pseudomallei Infection.
Memory Disorders
Effects of batroxobin on spatial learning and memory disorder of rats with temporal ischemia and the expression of HSP32 and HSP70.
Memory Disorders
S-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase.
Meningioma
Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells.
Meningioma
Possible mechanism of heme oxygenase-1 expression in rat malignant meningioma KMY-J cells subjected to talaporfin sodium-mediated photodynamic therapy.
Mesothelioma
Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells.
Mesothelioma, Malignant
Heme Oxygenase-1 Promoter Polymorphism is Associated with Risk of Malignant Mesothelioma.
Metabolic Diseases
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man.
Metabolic Diseases
Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?
Metabolic Diseases
New insights into intracellular locations and functions of heme oxygenase-1.
Metabolic Diseases
Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1.
Metabolic Syndrome
A Randomized Trial of Aspirin at Clinically Relevant Doses and Nitric Oxide Formation in Humans.
Metabolic Syndrome
Adipocyte Heme Oxygenase-1 Induction Attenuates Metabolic Syndrome in Both Male and Female Obese Mice.
Metabolic Syndrome
Association between heme oxygenase-1 gene promoter polymorphisms and metabolic syndrome in Iranians.
Metabolic Syndrome
Association of HMOX1 and NQO1 Polymorphisms with Metabolic Syndrome Components.
Metabolic Syndrome
Correlation between lipid profile and heme oxygenase system in patients with benign prostatic hyperplasia.
Metabolic Syndrome
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.
Metabolic Syndrome
Cross-Talk Between Body Iron Stores and Diabetes: Iron Stores are Associated with Activity and Microsatellite Polymorphism of the Heme Oxygenase and Type 2 Diabetes.
Metabolic Syndrome
Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications.
Metabolic Syndrome
Heme oxygenase-1 alleviates vascular complications associated with metabolic syndrome: Effect on endothelial dependent relaxation and NO production.
Metabolic Syndrome
Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy.
Metabolic Syndrome
Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet.
Metabolic Syndrome
The Effects of Heme Oxygenase Upregulation on Obesity and the Metabolic Syndrome.
Metabolic Syndrome
Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome.
Microvascular Angina
Subjects with microvascular angina have longer GT repeats polymorphism in the haem oxygenase-1 gene promoter.
Mitral Valve Stenosis
Heme oxygenase derived carbon monoxide and iron mediated plasmatic hypercoagulability in a patient with calcific mitral valve disease.
Mouth Neoplasms
Induction of peroxiredoxin 1 by hypoxia regulates heme oxygenase-1 via NF-?B in oral cancer.
Mouth Neoplasms
Involvement of Nrf2-mediated upregulation of heme oxygenase-1 in mollugin-induced growth inhibition and apoptosis in human oral cancer cells.
Mouth Neoplasms
Isoliquiritigenin 2'-methyl ether induces growth inhibition and apoptosis in oral cancer cells via heme oxygenase-1.
Mouth Neoplasms
MAPK/JNK1 activation protects cells against cadmium-induced autophagic cell death via differential regulation of catalase and heme oxygenase-1 in oral cancer cells.
Mouth Neoplasms
Retracted: Involvement of Nrf2-Mediated Upregulation of Heme Oxygenase-1 in Mollugin-Induced Growth Inhibition and Apoptosis in Human Oral Cancer Cells.
Movement Disorders
Evaluation of salivary heme oxygenase-1 as a potential biomarker of early Parkinson's disease.
Mucocutaneous Lymph Node Syndrome
Polymorphisms of heme oxygenase-1 and bilirubin UDP-glucuronosyltransferase genes are not associated with Kawasaki disease susceptibility.
Multiple Myeloma
Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma.
Multiple Myeloma
Heme oxygenase-1 attenuates the inhibitory effect of bortezomib against the APRIL-NF-?B-CCL3 signaling pathways in multiple myeloma cells: Corelated with bortezomib tolerance in multiple myeloma.
Multiple Myeloma
Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis.
Multiple Myeloma
Overexpression of heme oxygenase-1 in bone marrow stromal cells promotes multiple myeloma resistance through the JAK2/STAT3 pathway.
Multiple Sclerosis
Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis.
Multiple Sclerosis
Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis.
Multiple Sclerosis
Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement.
Multiple Sclerosis
Heme oxygenase-1 expression in peripheral blood mononuclear cells correlates with disease activity in multiple sclerosis.
Multiple Sclerosis
Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitis.
Multiple Sclerosis
Microsatellite polymorphism in haem oxygenase 1 gene promoter in multiple sclerosis.
Multiple Sclerosis
Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia.
Multiple Sclerosis
Proinflammatory cytokines promote glial heme oxygenase-1 expression and mitochondrial iron deposition: implications for multiple sclerosis.
Muscular Atrophy
A FoxO1-dependent, but NRF2-independent induction of heme oxygenase-1 during muscle atrophy.
Muscular Atrophy
Hemin, heme oxygenase-1 inducer, attenuates immobilization-induced skeletal muscle atrophy in mice.
Muscular Atrophy
Quercetin Reduces Tumor Necrosis Factor Alpha-Induced Muscle Atrophy by Upregulation of Heme Oxygenase-1.
Muscular Diseases
Human septic myopathy: induction of cyclooxygenase, heme oxygenase and activation of the ubiquitin proteolytic pathway.
Muscular Dystrophy, Duchenne
Heme Oxygenase-1 Influences Satellite Cells and Progression of Duchenne Muscular Dystrophy in Mice.
Mycobacterium Infections
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Mycoses
ROS-induced Oxidative Injury involved in Pathogenesis of Fungal Keratitis via p38 MAPK Activation.
Myelodysplastic Syndromes
Myelodysplastic syndrome macrophages have aberrant iron storage and heme oxygenase-1 expression.
Myelodysplastic Syndromes
Role of heme oxygenase-1 in demethylating effects on SKM-1 cells induced by decitabine.
Myocardial Infarction
A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia.
Myocardial Infarction
Bilirubin Levels and the Burden of Coronary Atherosclerosis in Patients With STEMI.
Myocardial Infarction
Bilirubin Levels and Thrombus Burden in Patients With ST-Segment Elevation Myocardial Infarction.
Myocardial Infarction
Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species.
Myocardial Infarction
Change in bilirubin level following acute myocardial infarction is an index for heme oxygenase activation.
Myocardial Infarction
Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarction.
Myocardial Infarction
Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction.
Myocardial Infarction
Expression of heme oxygenase-1 in response to myocardial infarction in rats.
Myocardial Infarction
Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (the Ludwigshafen Risk and Cardiovascular Health study).
Myocardial Infarction
Ginsenoside Rg2 attenuates myocardial fibrosis and improves cardiac function after myocardial infarction via AKT signaling pathway.
Myocardial Infarction
Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function.
Myocardial Infarction
Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B.
Myocardial Infarction
Heme Oxygenase-1 Induction Improves Cardiac Function following Myocardial Ischemia by Reducing Oxidative Stress.
Myocardial Infarction
Heme oxygenase-1 induction protects the heart and modulates cellular and extracellular remodelling after myocardial infarction in rats.
Myocardial Infarction
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
Myocardial Infarction
Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca(2+) channels.
Myocardial Infarction
Hydrogen sulfide restores sevoflurane postconditioning mediated cardioprotection in diabetic rats: Role of SIRT1/Nrf2 signaling-modulated mitochondrial dysfunction and oxidative stress.
Myocardial Infarction
Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector.
Myocardial Infarction
Leptin modulates gene expression in the heart and cardiomyocytes towards mitigating ischemia-induced damage.
Myocardial Infarction
MST1-Hippo pathway regulates inflammation response following myocardial infarction through inhibiting HO-1 signaling pathway.
Myocardial Infarction
New strategies for cardiovascular gene therapy: regulatable pre-emptive expression of pro-angiogenic and antioxidant genes.
Myocardial Infarction
Plasma bilirubin values on admission and ventricular remodeling after a first anterior ST-segment elevation acute myocardial infarction.
Myocardial Infarction
Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction.
Myocardial Infarction
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Myocardial Infarction
Splenic Ly6C(hi) monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice.
Myocardial Infarction
The expression of myeloperoxidase in thrombi is associated with reduced heme oxygenase-1 induction and worse left ventricular remodeling in patients with acute ST-elevation myocardial infarction.
Myocardial Infarction
Three-dimensional echocardiography in the diagnosis of myocardial infarction and its correlation with the expressions of serum HIF-1?, HO-1 and VEGF.
Myocardial Infarction
[Clinical study on changes of heme oxygenase-1 expression in patients with acute myocardial infarction]
Myocardial Infarction
[Long-term effects of heme oxygenase 1 overexpression on post-infarction heart function in diabetic rats].
Myocardial Infarction
[Transplantation of bone marrow cells up-regulated the expressions of HSP32 and HSP70 in the acute ischemic myocardium]
Myocardial Ischemia
A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese.
Myocardial Ischemia
Enhanced expression and localization of heme oxygenase-1 during recovery phase of porcine stunned myocardium.
Myocardial Ischemia
Heme Oxygenase-1 Induction Improves Cardiac Function following Myocardial Ischemia by Reducing Oxidative Stress.
Myocardial Ischemia
Heme oxygenase-1: An important therapeutic target for protecting against myocardial ischemia and reperfusion injury.
Myocardial Ischemia
Impact of anti-apoptotic and anti-oxidative effects of bone marrow mesenchymal stem cells with transient overexpression of heme oxygenase-1 on myocardial ischemia.
Myocardial Ischemia
Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion.
Myocardial Ischemia
Upregulation of heme oxygenase-1 expression for protecting against myocardial ischemia and reperfusion injury.
Myocardial Reperfusion Injury
Effects of intracoronary delivery of allogenic bone marrow-derived stem cells expressing heme oxygenase-1 on myocardial reperfusion injury.
Myocardial Stunning
Enhanced expression and localization of heme oxygenase-1 during recovery phase of porcine stunned myocardium.
Myocarditis
Heme oxygenase-1 mediates oxidative stress and apoptosis in coxsackievirus b3-induced myocarditis.
Myocarditis
[Effects of hemoglobin oxygenase-1 inhibitor zinc protoporphyrin IX on acute viral myocarditis in mice]
Myxoma
Left atrial myxoma presenting as pulmonary embolism: potential role of heme oxygenase-1.
Nasal Polyps
Expression of heme oxygenase-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps: modulation by cytokines.
Nasal Polyps
[Expression of heme oxygenase-1 in nasal polyps and regulation by glucocorticoid].
Nasopharyngeal Carcinoma
High expression of heme oxygenase-1 in tumor-associated macrophages characterizes a poor-prognosis subtype in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Implication of heme oxygenase-1 in the sensitivity of nasopharyngeal carcinomas to radiotherapy.
Neoplasm Metastasis
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
Neoplasm Metastasis
Association between GT-repeat polymorphism at heme oxygenase-1 gene promoter and gastric cancer and metastasis.
Neoplasm Metastasis
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.
Neoplasm Metastasis
Curcumin-induced heme oxygenase-1 expression plays a negative role for its anti-cancer effect in bladder cancers.
Neoplasm Metastasis
Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice.
Neoplasm Metastasis
Effects of ellagic Acid on angiogenic factors in prostate cancer cells.
Neoplasm Metastasis
Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53.
Neoplasm Metastasis
Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer.
Neoplasm Metastasis
Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis.
Neoplasm Metastasis
Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas.
Neoplasm Metastasis
Heme Oxygenase-1 Inhibits Tumor Metastasis Mediated By Notch1 Pathway In Murine Mammary Carcinoma.
Neoplasm Metastasis
Heme Oxygenase-1 Is a Pivotal Modulator of Bone Turnover and Remodeling: Molecular Implications for Prostate Cancer Bone Metastasis.
Neoplasm Metastasis
Heme oxygenase-1 is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK Pathway, and mediates anti-apoptotic signal.
Neoplasm Metastasis
Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity.
Neoplasm Metastasis
Heme oxygenase-1: a molecular brake on hepatocellular carcinoma cell migration.
Neoplasm Metastasis
In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis.
Neoplasm Metastasis
Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis.
Neoplasm Metastasis
MiRNA-15a-3p inhibits the metastasis of hepatocellular carcinoma by interacting with HMOX1.
Neoplasm Metastasis
Myeloid tumor necrosis factor and heme oxygenase-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion.
Neoplasm Metastasis
Pathological roles of c-Met in bladder cancer: Association with cyclooxygenase-2, heme oxygenase-1, vascular endothelial growth factor-A and programmed death ligand 1.
Neoplasm Metastasis
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Neoplasm Metastasis
The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer.
Neoplasm Metastasis
ZnPPIX inhibits peritoneal metastasis of gastric cancer via its antiangiogenic activity.
Neoplasm Metastasis
[Effects of heme oxygenase-1 knockdown on proliferation, invasion and metastasis of lung adenocarcinoma A549 cells and its mechanism].
Neoplasms
14-3-3? inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Neoplasms
15d-PGJ2 inhibits NF-?B and AP-1-mediated MMP-9 expression and invasion of breast cancer cell by means of a heme oxygenase-1-dependent mechanism.
Neoplasms
2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways.
Neoplasms
27 OXIDATIVE STRESS OF LIVER IN TRANSGENIC PIGLETS WITH MULTIPLE COPIES OF TRANSGENES SOLUBLE HUMAN TUMOUR NECROSIS FACTOR RECEPTOR TYPE Ig-Fc AND HUMAN HEME OXYGENASE-1.
Neoplasms
5-Aminolevulinic acid regulates the inflammatory response and alloimmune reaction.
Neoplasms
A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H2O2, and produce large amounts CO for a highly efficient treatment of osteoarthritis.
Neoplasms
A Near-Infrared Probe Tracks and Treats Lung Tumor Initiating Cells by Targeting HMOX2.
Neoplasms
A Parkinson's disease gene, DJ-1, regulates anti-inflammatory roles of astrocytes through prostaglandin D2 synthase expression.
Neoplasms
A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival.
Neoplasms
A transient inflammatory reaction in the lung after experimental hemorrhagic shock and resuscitation with a hemoglobin-vesicles solution compared with rat RBC transfusion.
Neoplasms
Ablation of the tumor suppressor histidine triad nucleotide binding protein 1 is protective against hepatic ischemia/reperfusion injury.
Neoplasms
Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression.
Neoplasms
Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness.
Neoplasms
Achillea millefolium L. Essential Oil Inhibits LPS-Induced Oxidative Stress and Nitric Oxide Production in RAW 264.7 Macrophages.
Neoplasms
Action of prolactin, IFN-gamma, TNF-alpha and LPS on heme oxygenase-1 expression and VEGF release in human monocytes/macrophages.
Neoplasms
Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.
Neoplasms
Activation of the Nrf2/ARE signaling pathway by probucol contributes to inhibiting inflammation and neuronal apoptosis after spinal cord injury.
Neoplasms
Activity of heme oxygenase-1 affects expression levels of hypoxia inducible factor-1 gene in vitro.
Neoplasms
Acute effects of diesel emission from the urea selective catalytic reduction engine system on male rats.
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Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice.
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Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin.
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Albumin Limits Mesenteric Endothelial Dysfunction and Inflammatory Response in Cardiopulmonary Bypass.
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Alterations in hepatic heme and cytochrome P-450 metabolism in Murphy-Sturm lymphosarcoma-bearing rats. Implications for drug metabolism.
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Alterations of hepatic delta-aminolevulinic acid synthetase, heme oxygenase, microsomal cytochrome content and drug metabolism in rats bearing ascitic tumors AH 13, AH 66 and AH 414 and a 3-methylcholanthrene induced tumor.
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Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth.
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Amelioration of estrogen-induced endometrial hyperplasia in female rats by hemin via heme-oxygenase-1 expression, suppression of iNOS, p38MAPK and Ki67.
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Ameliorative Effect of Coenzyme Q10 and/or Candesartan on Carboplatin-Induced Nephrotoxicity: Roles of Apoptosis, Transforming Growth Factor-?1, Nuclear Factor Kappa-B And The Nrf2/HO-1 Pathway
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Ameliorative effect of N-acetyl cysteine on alpha-cypermethrin-induced pulmonary toxicity in male rats.
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Ameliorative potential of sitagliptin and/or resveratrol on experimentally-induced clear cell renal cell carcinoma.
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Ameliorative role of curcumin on copper oxide nanoparticles-mediated renal toxicity in rats: An investigation of molecular mechanisms.
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An antibody-based enzymatic therapy for cancer treatment: The selective localization of D-amino acid oxidase to EDA fibronectin.
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Analysis of Macrophage Activation Markers in an Experimental Model of Cutaneous Leishmaniasis Treated with Photodynamic Therapy Mediated by 5-Aminolevulinic Acid.
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Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsia.
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Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in A?1-42-Induced Mice.
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Anti-inflammatory effects of Saururus chinensis aerial parts in murine macrophages via induction of heme oxygenase-1.
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Anti-inflammatory potential of curcumin and quercetin in rats: Role of oxidative stress, heme oxygenase-1 and TNF-?
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Anti-oxidative and anti-inflammatory effects of Rosa Mosqueta oil supplementation in rat liver ischemia-reperfusion.
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Antitumor Effect of 5-Aminolevulinic Acid Through Ferroptosis in Esophageal Squamous Cell Carcinoma.
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Aspirin-triggered resolvin D1 alleviates paraquat-induced acute lung injury in mice.
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Association between heme oxygenase-1 gene promoter polymorphisms and cancer susceptibility: A meta-analysis.
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Association between the (GT)n polymorphism of the HO-1 gene promoter region and cancer risk: a meta-analysis.
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Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation.
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Association of heme oxygenase-1 polymorphisms with cancer risk: A systematic review and meta-analysis.
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Atrial natriuretic peptide alleviates cardiovascular and metabolic disorders in a rat endotoxemia model: a possible role for its anti-inflammatory properties.
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Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.
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Aucubin administered by either oral or parenteral route protects against cisplatin-induced acute kidney injury in mice.
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Balancing anti-inflammatory and anti-oxidant responses in murine bone marrow derived macrophages.
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Beneficial effects of the transgenic expression of human sTNF-?R-Fc and HO-1 on pig-to-mouse islet xenograft survival.
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Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms.
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Betulinic acid attenuates lipopolysaccharide-induced vascular hyporeactivity in the rat aorta by modulating Nrf2 antioxidative function.
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Biodegradable Copper-Based Nanoparticles Augmented Chemodynamic Therapy through Deep Penetration and Suppressing Antioxidant Activity in Tumors.
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Bioeffects of low-intensity ultrasound in vitro: apoptosis, protein profile alteration, and potential molecular mechanism.
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Bismuth Sulfide Nanorods with Retractable Zinc Protoporphyrin Molecules for Suppressing Innate Antioxidant Defense System and Strengthening Phototherapeutic Effects.
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Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer.
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Brain vessels normally undergo cyclic activation and inactivation: evidence from tumor necrosis factor-alpha, heme oxygenase-1, and manganese superoxide dismutase immunostaining of vessels and perivascular brain cells.
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Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages.
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Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin.
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Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition.
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Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors.
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Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-?- and Interleukin-1?-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway.
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Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms.
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Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice.
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CD4+ CD25+ FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas.
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Changes in expression of genes encoding antioxidant enzymes, heme oxygenase-1, Bcl-2, and Bcl-xl and in level of reactive oxygen species in tumor cells resistant to doxorubicin.
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Characterization of docosahexaenoic acid (DHA)-induced heme oxygenase-1 (HO-1) expression in human cancer cells: the importance of enhanced BTB and CNC homology 1 (Bach1) degradation.
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Chijabyukpi-Tang Inhibits Pro-Inflammatory Cytokines and Chemokines via the Nrf2/HO-1 Signaling Pathway in TNF-?/IFN-?-Stimulated HaCaT Cells and Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice.
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Chloropicrin induces endoplasmic reticulum stress in human retinal pigment epithelial cells.
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Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers.
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Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: nuclear HO-1 promotes vascular endothelial growth factor secretion.
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Clinical outcomes and genetic expression profile in human liver graft dysfunction during ischemia/reperfusion injury.
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Clofibrate induces heme oxygenase 1 expression through a PPAR?-independent mechanism in human cancer cells.
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Co-expression of thymidine phosphorylase and heme oxygenase-1 in macrophages in human malignant vertical growth melanomas.
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Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity.
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Combination therapy with human umbilical cord mesenchymal stem cells and angiotensin-converting enzyme 2 is superior for the treatment of acute lung ischemia-reperfusion injury in rats.
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Combined effect of substance P and curcumin on cutaneous wound healing in diabetic rats.
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Comparison of m-RNA expression for inflammatory mediators in leukocytes between on-pump and off-pump coronary artery bypass grafting.
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Computational Designing and Prediction of ADMET Properties of Four Novel Imidazole-Based Drug Candidates Inhibiting Heme Oxygenase-1 Causing Cancers.
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Computational pharmacology and bioinformatics to explore the potential mechanism of Schisandra against atherosclerosis.
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Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate.
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Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms.
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Costunolide inhibits production of tumor necrosis factor-alpha and interleukin-6 by inducing heme oxygenase-1 in RAW264.7 macrophages.
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Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.
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Curcumin-induced heme oxygenase-1 expression plays a negative role for its anti-cancer effect in bladder cancers.
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Cypermethrin-Induced Nigrostriatal Dopaminergic Neurodegeneration Alters the Mitochondrial Function:A Proteomics Study.
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Cytotoxicity and Pro-/Anti-inflammatory Properties of Cinnamates, Acrylates and Methacrylates Against RAW264.7 Cells.
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d-Limonene protects PC12 cells against corticosterone-induced neurotoxicity by activating the AMPK pathway.
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Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-? Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats.
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Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment.
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Development of an alternative zebrafish model for drug-induced intestinal toxicity.
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Dietary exposure to bisphenol A affects memory function and neuroimmune biomarkers in allergic asthmatic mice.
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Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells.
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Differential effects of resveratrol and its natural analogs, piceatannol and 3,5,4'-trans-trimethoxystilbene, on anti-inflammatory heme oxigenase-1 expression in RAW264.7 macrophages.
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Differential regulation of cytochrome P450 isozyme mRNAs and proteins by femur fracture trauma.
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Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner.
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Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity.
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Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases.
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Distinct cell-types in the prostate share an aging signature suggestive of metabolic reprogramming.
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DL-3-n-butylphthalide extends survival by attenuating glial activation in a mouse model of amyotrophic lateral sclerosis.
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DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes.
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Docosahexaenoic acid suppresses neuroinflammatory responses and induces heme oxygenase-1 expression in BV-2 microglia: implications of antidepressant effects for omega-3 fatty acids.
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Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.
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Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice.
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East to West not North-West: Structure-Based Mechanistic Resolution of 8-Hydroxyl Replacement and Resulting Effects on the Activities of Imidazole-Based Heme Oxygenase-1 Inhibitors.
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Effect of combination sildenafil and gemfibrozil on cisplatin-induced nephrotoxicity; role of heme oxygenase-1.
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Effect of growth hormone treatment on pancreatic inflammation, oxidative stress, and apoptosis related to aging in SAMP8 mice.
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Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan.
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Effect of Heme Oxygenase-1 on Melanoma Development in Mice-Role of Tumor-Infiltrating Immune Cells.
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Effect of Selenium Against Lead-Induced Damage on the Gene Expression of Heat Shock Proteins and Inflammatory Cytokines in Peripheral Blood Lymphocytes of Chickens.
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Effect of Trolox on altered vasoregulatory gene expression in hepatic ischemia/reperfusion.
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Effect of tumor necrosis factor-alpha and interleukin-1 alpha on heme oxygenase-1 expression in human endothelial cells.
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Effects of dietary tryptophan levels on antioxidant status and immunity for juvenile blunt snout bream (Megalobrama amblycephala) involved in Nrf2 and TOR signaling pathway.
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Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
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Embelin attenuates cisplatin-induced nephrotoxicity: Involving inhibition of oxidative stress and inflammation in addition with activation of Nrf-2/Ho-1 pathway.
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Emerging roles of cadmium and heme oxygenase in type-2 diabetes and cancer susceptibility.
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Endogenous Estrogen-Mediated Heme Oxygenase Regulation in Experimental Menopause.
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Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53.
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Engineered Polymeric Micelles for Combinational Oxidation Anticancer Therapy through Concurrent HO-1 Inhibition and ROS Generation.
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Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application.
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Enhanced effect of human mesenchymal stem cells expressing human TNF-?R-Fc and HO-1 gene on porcine islet xenotransplantation in humanized mice.
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Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
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Enhancement of heme oxygenase expression and activity in A431 squamous carcinoma multicellular tumor spheroids.
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Epidermal growth factor stimulates nuclear factor-?B activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
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Epigallocatechin gallate-mediated protection against tumor necrosis factor-?-induced monocyte chemoattractant protein-1 expression is heme oxygenase-1 dependent.
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Exercise training in intermittent claudication: effects on antioxidant genes, inflammatory mediators and proangiogenic progenitor cells.
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Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats.
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Expression changes of inflammatory cytokines TNF-?, IL-1? and HO-1 in hematoma surrounding brain areas after intracerebral hemorrhage.
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Expression of heme oxygenase-1 (HSP32) in human prostate: normal, hyperplastic, and tumor tissue distribution.
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Expression of hepatic vascular stress genes following ischemia/reperfusion and subsequent endotoxemia.
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Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate.
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Expression of oxidative stress-responsive genes and cytokine genes during caerulein-induced acute pancreatitis.
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Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor Growth.
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Fatty acid epoxyisoprostane E2 stimulates an oxidative stress response in endothelial cells.
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FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway.
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Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.
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Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy.
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Functional dissection of Nrf2-dependent phase II genes in vascular inflammation and endotoxic injury using Keap1 siRNA.
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Gamma-tocopherol supplementation ameliorated hyper-inflammatory response during the early cutaneous wound healing in alloxan-induced diabetic mice.
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Gastroprotective effect of ghrelin against indomethacin-induced gastric injury in rats: possible role of heme oxygenase-1 pathway.
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Generation by somatic cell nuclear transfer of GGTA1 knockout pigs expressing soluble human TNFRI-Fc and human HO-1.
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Genetic and histopathological alterations induced by cypermethrin in rat kidney and liver: Protection by sesame oil.
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Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
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Glucocorticoid-induced Tumor Necrosis Factor Receptor Negatively Regulates Activation of Human Primary Natural Killer (NK) Cells by Blocking Proliferative Signals and Increasing NK Cell Apoptosis.
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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
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Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells.
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Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma.
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Heme Oxygenase 1-Targeted Hybrid Nanoparticle for Chemo- and Immuno-Combination Therapy in Acute Myelogenous Leukemia.
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Heme oxygenase and carbon monoxide as an immunotherapeutic approach in transplantation and cancer.
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Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells.
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Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma.
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Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis.
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Heme oxygenase-1 expression is associated with tumor aggressiveness and outcomes in patients with bladder cancer: a correlation with smoking intensity.
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Heme oxygenase-1 gene promoter polymorphism is associated with risk of gastric adenocarcinoma and lymphovascular tumor invasion.
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Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer.
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Heme oxygenase-1 has antitumoral effects in colorectal cancer: involvement of p53.
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Heme oxygenase-1 in pregnancy and cancer: similarities in cellular invasion, cytoprotection, angiogenesis, and immunomodulation.
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Heme Oxygenase-1 Induction and Anti-inflammatory Actions of Atractylodes macrocephala and Taraxacum herba Extracts Prevented Colitis and Was More Effective than Sulfasalazine in Preventing Relapse.
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Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis.
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Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma.
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Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.
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Heme Oxygenase-1 Inhibitors Induce Cell Cycle Arrest and Suppress Tumor Growth in Thyroid Cancer Cells.
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Heme Oxygenase-1 Inhibits Tumor Metastasis Mediated By Notch1 Pathway In Murine Mammary Carcinoma.
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Heme oxygenase-1 is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK Pathway, and mediates anti-apoptotic signal.
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Heme oxygenase-1 messenger RNA expression is induced in peripheral blood mononuclear cells of pediatric cancer patients with systemic inflammatory response syndrome.
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Heme oxygenase-1 plays a crucial role in chemoresistance in acute myeloid leukemia.
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Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules.
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Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity.
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Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells.
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Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity.
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Heme oxygenase-1 retards hepatocellular carcinoma progression through the microRNA pathway.
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Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis.
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Heme oxygenase-1/carbon monoxide axis suppresses transforming growth factor-?1-induced growth inhibition by increasing ERK1/2-mediated phosphorylation of Smad3 at Thr-179 in human hepatocellular carcinoma cell lines.
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High expression of heme oxygenase-1 is associated with tumor invasiveness and poor clinical outcome in non-small cell lung cancer patients.
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High Glucose Promotes Tumor Invasion and Increases Metastasis-Associated Protein Expression in Human Lung Epithelial Cells by Upregulating Heme Oxygenase-1 via Reactive Oxygen Species or the TGF-?1/PI3K/Akt Signaling Pathway.
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HMOX1 is an important prognostic indicator of nonmuscle invasive bladder cancer recurrence and progression.
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Hmox1 Upregulation Is a Mutual Marker in Human Tumor Cells Exposed to Physical Plasma-Derived Oxidants.
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HO-1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy.
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HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib.
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HPV16 E2 protein promotes innate immunity by modulating immunosuppressive status.
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HSP32 and HSP90 Immunoexpression, in Relation to Kit Pattern, Grading, and Mitotic Count in Canine Cutaneous Mast Cell Tumors.
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Human Heme Oxygenase-1 Induced by Interleukin-6 via JAK/STAT3 Pathways Is a Tumor Suppressor Gene in Hepatoma Cells.
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Human mesenchymal stromal cells suppress T-cell proliferation independent of heme oxygenase-1.
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Hydrogen Gas Alleviates the Intestinal Injury Caused by Severe Sepsis in Mice by Increasing the Expression of Heme Oxygenase-1.
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Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.
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Hydrogen sulfide attenuates renal I/R?induced activation of the inflammatory response and apoptosis via regulating Nrf2?mediated NLRP3 signaling pathway inhibition.
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Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation and Structure Induced by Neonatal Hyperoxia in Mice (Mus musculus).
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Implication of heme oxygenase-1 in the sensitivity of nasopharyngeal carcinomas to radiotherapy.
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In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats.
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In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor.
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In Vivo Hemin Conditioning Targets the Vascular and Immunologic Compartments and Restrains Prostate Tumor Development.
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Increase of IFN-? and TNF-? production in CD107a?+?NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor.
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Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression.
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Increasing Heme Oxygenase-1-Expressing Macrophages Indicates a Tendency of Poor Prognosis in Advanced Colorectal Cancer.
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Individual and co-expression patterns of nerve growth factor and heme oxygenase-1 predict shorter survival of gastric carcinoma patients.
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Indolyl-chalcone derivatives induce hepatocellular carcinoma cells apoptosis through oxidative stress related mitochondrial pathway in vitro and in vivo.
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Induction of heme oxygenase 1 and inhibition of tumor necrosis factor alpha-induced intercellular adhesion molecule expression by andrographolide in EA.hy926 cells.
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Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy.
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Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones.
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Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza.
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Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
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Inhibition of 7,12-Dimethylbenz(a)anthracene-Induced Skin Tumorigenesis in C57BL/6 Mice by Sulforaphane Is Mediated by Nuclear Factor E2-Related Factor 2.
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Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis.
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Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice.
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Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy.
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Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice.
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Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin.
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Inhibition of heme oxygenase-1 enhances the cytotoxic effect of gemcitabine in urothelial cancer cells.
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Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment.
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Interleukin-1 and tumour necrosis factor induce hepatic haem oxygenase. Feedback regulation by glucocorticoids.
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Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis.
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Interplay of MKP-1 and Nrf2 drives tumor growth and drug resistance in non-small cell lung cancer.
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Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups
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Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups.
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Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment.
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Investigation of the effects of short-term inhalation of carbon nanoparticles on brains and lungs of c57bl/6j and p47(phox-/-) mice.
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Involvement of tumor necrosis factor alpha, rather than interleukin-1alpha/beta or nitric oxides in the heme oxygenase-1 gene expression by lipopolysaccharide in the mouse liver.
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Iron metabolism gene expression and prognostic features of hepatocellular carcinoma.
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Is bilirubin a marker of vascular disease and/or cancer and is it a potential therapeutic target?
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Left atrial myxoma presenting as pulmonary embolism: potential role of heme oxygenase-1.
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Lentivirus-mediated interleukin-1? (IL-1?) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice.
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Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
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Light-induced cytotoxicity after aminolevulinic acid treatment is mediated by heme and not by iron.
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Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll-like receptor 4, TGF-?1, NF-?B and glucagon-like peptide 1.
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Liver graft preservation using perfluorocarbon improves the outcomes of simulated donation after cardiac death liver transplantation in rats.
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Low heme oxygenase-1 expression promotes gastric cancer cell apoptosis, inhibits proliferation and invasion, and correlates with increased overall survival in gastric cancer patients.
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Luteolin ameliorates dextran sulfate sodium-induced colitis in mice possibly through activation of the Nrf2 signaling pathway.
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Magnolia bioactive constituent 4-O-methylhonokiol prevents the impairment of cardiac insulin signaling and the cardiac pathogenesis in high-fat diet-induced obese mice.
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Mechanical stress activates proinflammatory cytokines and antioxidant defense enzymes in human dental pulp cells.
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Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
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Mechanisms underlying the perifocal neuroprotective effect of the Nrf2-ARE signaling pathway after intracranial hemorrhage.
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Meeting report: ISN forefronts in nephrology on endothelial biology and renal disease: from bench to prevention.
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Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway.
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Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.
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Metformin Inhibits Lipoteichoic Acid-Induced Oxidative Stress and Inflammation Through AMPK/NRF2/NF-?B Signaling Pathway in Bovine Mammary Epithelial Cells.
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METH-Induced Neurotoxicity Is Alleviated by Lactulose Pretreatment Through Suppressing Oxidative Stress and Neuroinflammation in Rat Striatum.
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Micheliolide Protects Against Doxorubicin-Induced Cardiotoxicity in Mice by Regulating PI3K/Akt/NF-kB Signaling Pathway.
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Microarray analysis uncovers retinoid targets in human bronchial epithelial cells.
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Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
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MicroRNA-155 and microRNA-181a, via HO-1, participate in regulating the immunotoxicity of cadmium in the kidneys of exposed Cyprinus carpio.
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microRNA-494 Favors HO-1 Expression in Neuroblastoma Cells Exposed to Oxidative Stress in a Bach1-Independent Way.
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Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients.
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MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth.
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MiR-200c sensitizes clear-cell renal cell carcinoma cells to sorafenib and imatinib by targeting heme oxygenase-1.
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miR-24 targets HMOX1 to regulate inflammation and neurofunction in rats with cerebral vasospasm after subarachnoid hemorrhage.
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Modulation of hormone-dependent glucocorticoid receptor function using a tetracycline-regulated expression system.
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Modulation of inflammatory response by selective inhibition of cyclooxygenase-1 and cyclooxygenase-2 in acute kidney injury.
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Modulation of the JAK/ERK/STAT signaling in melanocortin-induced inhibition of local and systemic responses to myocardial ischemia/reperfusion.
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Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis.
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Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2.
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Molecular pathways: Fumarate hydratase-deficient kidney cancer--targeting the Warburg effect in cancer.
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Multi-targeted protection of acetaminophen-induced hepatotoxicity in mice by tannic acid.
Neoplasms
Mycophenolate mofetil attenuates concanavalin A-induced acute liver injury through modulation of TLR4/NF-?B and Nrf2/HO-1 pathways.
Neoplasms
Myeloid tumor necrosis factor and heme oxygenase-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion.
Neoplasms
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Neoplasms
Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO-1/NF-?B signaling pathway.
Neoplasms
NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction.
Neoplasms
Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism.
Neoplasms
Nitrogen Dioxide and Ultrafine Particles Dominate the Biological Effects of Inhaled Diesel Exhaust Treated by a Catalyzed Diesel Particulate Filter.
Neoplasms
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation.
Neoplasms
Non-invasive Assessment of Fecal Stress Biomarkers in Hunting Dogs During Exercise and at Rest.
Neoplasms
Non-mitogenic FGF2 protects cardiomyocytes from acute doxorubicin-induced toxicity independently of the protein kinase CK2/heme oxygenase-1 pathway.
Neoplasms
Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.
Neoplasms
Nrf2-dependent induction of human ABC transporter ABCG2 and heme oxygenase-1 in HepG2 cells by photoactivation of porphyrins: biochemical implications for cancer cell response to photodynamic therapy.
Neoplasms
Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases.
Neoplasms
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
Neoplasms
Nuclear factor erythroid 2-related factor 2 (Nrf2), tumor necrosis factor alpha protein (TNF-?), heme oxygenase-1 (HO-1) gene expressions during cardiopulmonary bypass.
Neoplasms
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses.
Neoplasms
Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas.
Neoplasms
Nuclear translocation of heme oxygenase-1 confers resistance to Imatinib in chronic myeloid leukemia cells.
Neoplasms
Nur77 attenuates inflammatory responses and oxidative stress by inhibiting phosphorylated I?B-? in Parkinson's disease cell model.
Neoplasms
Oligonol prevented the relapse of dextran sulfate sodium-ulcerative colitis through enhancing NRF2-mediated antioxidative defense mechanism.
Neoplasms
Omega-3 fatty acids protect against acetaminophen-induced hepatic and renal toxicity in rats through HO-1-Nrf2-BACH1 pathway.
Neoplasms
Opposite expression of the antioxidant heme oxygenase-1 in primary cells and tumor cells: regulation by interaction of USF-2 and Fra-1.
Neoplasms
Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage.
Neoplasms
Over-expression of heme oxygenase-1 in peripheral blood predicts the progression and relapse risk of chronic myeloid leukemia.
Neoplasms
Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice.
Neoplasms
Overexpression of heme oxygenase-1 induced by constitutively activated NF-?B as a potential therapeutic target for activated B-cell-like diffuse large B-cell lymphoma.
Neoplasms
Overexpression of the transcription factor FOXP3 in lung adenocarcinoma sustains malignant character by promoting G1/S transition gene CCND1.
Neoplasms
Overexpressions of HO-1/HO-1G143H in C57/B6J mice affect melanoma B16F10 lung metastases rather than change the survival rate of mice-bearing tumours.
Neoplasms
Oxidative stress in Fanconi anaemia: from cells and molecules toward prospects in clinical management.
Neoplasms
Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines.
Neoplasms
Oxidized Lipoproteins Promote Resistance to Cancer Immunotherapy Independent of Patient Obesity.
Neoplasms
P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex.
Neoplasms
Panax ginseng Fruit Has Anti-Inflammatory Effect and Induces Osteogenic Differentiation by Regulating Nrf2/HO-1 Signaling Pathway in In Vitro and In Vivo Models of Periodontitis.
Neoplasms
Pathological roles of c-Met in bladder cancer: Association with cyclooxygenase-2, heme oxygenase-1, vascular endothelial growth factor-A and programmed death ligand 1.
Neoplasms
Pathological significance and prognostic implications of heme oxygenase 1 expression in non-muscle-invasive bladder cancer: Correlation with cell proliferation, angiogenesis, lymphangiogenesis and expression of VEGFs and COX-2.
Neoplasms
Piceatannol alleviates inflammation and oxidative stress via modulation of the Nrf2/HO-1 and NF-?B pathways in diabetic cardiomyopathy.
Neoplasms
Pinitol attenuates LPS-induced pneumonia in experimental animals: Possible role via inhibition of the TLR-4 and NF-?B/I?B? signaling cascade pathway.
Neoplasms
Polydatin and polydatin-loaded chitosan nanoparticles attenuate diabetic cardiomyopathy in rats.
Neoplasms
Postneonatal Mortality and Liver Changes in Cloned Pigs Associated with Human Tumor Necrosis Factor Receptor I-Fc and Human Heme Oxygenase-1 Overexpression.
Neoplasms
Potential crosstalk of Ca2+-ROS-dependent mechanism involved in apoptosis of Kasumi-1 cells mediated by heme oxygenase-1 small interfering RNA.
Neoplasms
Potential crosstalk of the interleukin-6-heme oxygenase-1-dependent mechanism involved in resistance to lenalidomide in multiple myeloma cells.
Neoplasms
PPAR? activation sensitizes cancer cells to epigallocatechin-3-gallate (EGCG) treatment via suppressing heme oxygenase-1.
Neoplasms
Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis.
Neoplasms
Preliminary Analysis of the Expression of Selected Proangiogenic and Antioxidant Genes and MicroRNAs in Patients with Non-Muscle-Invasive Bladder Cancer.
Neoplasms
Pretreatment of Vitamin D3 Ameliorates Lung and Muscle Injury Induced by Reperfusion of Bilateral Femoral Vessels in a Rat Model.
Neoplasms
Proinflammatory cytokines promote glial heme oxygenase-1 expression and mitochondrial iron deposition: implications for multiple sclerosis.
Neoplasms
Prolongation of heart xenograft survival in a hamster-to-rat model after therapy with a rationally designed immunosuppressive peptide.
Neoplasms
Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury.
Neoplasms
Propyl gallate sensitizes human lung cancer cells to cisplatin-induced apoptosis by targeting heme oxygenase-1 for TRC8-mediated degradation.
Neoplasms
Protection of carbon monoxide inhalation on lipopolysaccharide-induced multiple organ injury in rats.
Neoplasms
Protective effect of short-term genistein supplementation on the early stage in diabetes-induced renal damage.
Neoplasms
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Neoplasms
Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-? and augmentation of interleukin-10.
Neoplasms
Protective effects of HV-P411 complex against D-galactosamine-induced hepatotoxicity in rats.
Neoplasms
Protective Effects of Hyperoside against Carbon Tetrachloride-Induced Liver Damage in Mice.
Neoplasms
Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats.
Neoplasms
Protective Effects of the Third Generation Vasodilatory ?eta - Blocker Nebivolol against D-Galactosamine - Induced Hepatorenal Syndrome in Rats.
Neoplasms
Protective mechanism of andrographolide against carbon tetrachloride-induced acute liver injury in mice.
Neoplasms
Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice.
Neoplasms
Protective role of heme oxygenase-1 in the intestinal tissue injury in an experimental model of sepsis.
Neoplasms
Protein network exploration prioritizes targets for modulating neuroinflammation in Parkinson's disease.
Neoplasms
Proteomic characterization of pancreatic islet {beta}-cells stimulated with pancreatic carcinoma cell conditioned medium.
Neoplasms
Proteomic characterization of Withaferin A-targeted protein networks for the treatment of monoclonal myeloma gammopathies.
Neoplasms
PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome.
Neoplasms
Pulmotoxicological effects caused by long-term titanium dioxide nanoparticles exposure in mice.
Neoplasms
Quercetin Potentiates Docosahexaenoic Acid to Suppress Lipopolysaccharide-induced Oxidative/Inflammatory Responses, Alter Lipid Peroxidation Products, and Enhance the Adaptive Stress Pathways in BV-2 Microglial Cells.
Neoplasms
Quercetin Reduces Tumor Necrosis Factor Alpha-Induced Muscle Atrophy by Upregulation of Heme Oxygenase-1.
Neoplasms
Re: Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Neoplasms
Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology.
Neoplasms
Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats.
Neoplasms
Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway.
Neoplasms
Relationships among pancreatic beta cell function, the Nrf2 pathway, and IRS2: a cross-sectional study.
Neoplasms
Resveratrol Improves Hepatic Redox Status and Lipid Balance of Neonates with Intrauterine Growth Retardation in a Piglet Model.
Neoplasms
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Neoplasms
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-?B Pathway.
Neoplasms
Role of HMOX1 Promoter Genetic Variants in Chemoresistance and Chemotherapy Induced Neutropenia in Children with Acute Lymphoblastic Leukemia.
Neoplasms
Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol.
Neoplasms
Roles of inflammation and apoptosis in experimental brain death-induced right ventricular failure.
Neoplasms
Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells.
Neoplasms
Rosa Mosqueta Oil Prevents Oxidative Stress and Inflammation through the Upregulation of PPAR-? and NRF2 in C57BL/6J Mice Fed a High-Fat Diet.
Neoplasms
S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidative Damage, Activation of Nrf2/ARE Binding, and BDNF Preservation.
Neoplasms
Sarcoid-Like Granulomatous Disease: Pathologic Case Series in World Trade Center Dust Exposed Rescue and Recovery Workers.
Neoplasms
Sevoflurane and isoflurane decrease TNF-alpha-induced gene expression in human monocytic THP-1 cells: Potential role of intracellular IkappaBalpha regulation.
Neoplasms
Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity.
Neoplasms
Silencing heme oxygenase-1 gene expression in retinal pigment epithelial cells inhibits proliferation, migration and tube formation of cocultured endothelial cells.
Neoplasms
Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor
Neoplasms
Simvastatin treatment ameliorates injury of rat testes induced by cadmium toxicity.
Neoplasms
Sinapic acid modulates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats.
Neoplasms
Smokeless tobacco extract inhibits proliferation and promotes apoptosis in oral mucous fibroblasts.
Neoplasms
Soluble factor from tumor cells induces heme oxygenase-1 by a nitric oxide-independent mechanism in murine peritoneal macrophages.
Neoplasms
Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1.
Neoplasms
Sour Cherry Seed Kernel Extract Increases Heme Oxygenase-1 Expression and Decreases Representation of CD3+ TNF-??+?and CD3?+?IL-8+ Subpopulations in Peripheral Blood Leukocyte Cultures from Type 2 Diabetes Patients.
Neoplasms
Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity.
Neoplasms
Styrene-maleic acid-copolymer conjugated zinc protoporphyrin as a candidate drug for tumor-targeted therapy and imaging.
Neoplasms
Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling.
Neoplasms
Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
Neoplasms
Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin.
Neoplasms
Sustained bile drainage decreases the organs injuries via inflammation-associated factors modulation in a severe acute pancreatitis rat model.
Neoplasms
Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells.
Neoplasms
Synergistic protective effect of FTY720 and vitamin E against simulated cerebral ischemia in vitro.
Neoplasms
Synthetically Lethal Interactions of Heme Oxygenase-1 and Fumarate Hydratase Genes.
Neoplasms
Systemic administration of autologous adipose-derived mesenchymal stem cells alleviates hepatic ischemia-reperfusion injury in rats.
Neoplasms
T cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue.
Neoplasms
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
Neoplasms
Targeting of Hsp32 in solid tumors and leukemias: a novel approach to optimize anticancer therapy.
Neoplasms
Tert-butylhydroquinone protects PC12 cells against ferrous sulfate-induced oxidative and inflammatory injury via the Nrf2/ARE pathway.
Neoplasms
TGF?-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme.
Neoplasms
The Activity of SV40 Promoter Can Be Inhibited by Overexpression of Heme Oxygenase-1 in Tumor Cells.
Neoplasms
The association of genotype polymorphisms with vascular access patency in hemodialysis patients.
Neoplasms
The balance mediated by miRNAs and the heme oxygenase 1 feedback loop contributes to biological effects.
Neoplasms
The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth.
Neoplasms
The Differential Tissue Expression of Inflammatory, Oxidative Stress, and Apoptosis Markers in Human Uncontrolled Non-Heart-Beating Donors.
Neoplasms
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes.
Neoplasms
The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells.
Neoplasms
The influence of palatable high-energy diet in diet-induced obesity pregnant rats on offspring oxidative stress in liver.
Neoplasms
The Introduction of Human Heme Oxygenase-1 and Soluble Tumor Necrosis Factor-? Receptor Type I With Human IgG1 Fc in Porcine Islets Prolongs Islet Xenograft Survival in Humanized Mice.
Neoplasms
The nitric oxide donor SIN-1 protects endothelial cells from tumor necrosis factor-alpha-mediated cytotoxicity: possible role for cyclic GMP and heme oxygenase.
Neoplasms
The novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cells.
Neoplasms
The novel N-methyl-d-aspartate receptor antagonist MN-08 ameliorates lipopolysaccharide-induced acute lung injury in mice.
Neoplasms
The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains.
Neoplasms
The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1.
Neoplasms
The Protect Effects of Chitosan Oligosaccharides on Intestinal Integrity by Regulating Oxidative Status and Inflammation under Oxidative Stress.
Neoplasms
The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer.
Neoplasms
The role of rhynchophylline in alleviating early brain injury following subarachnoid hemorrhage in rats.
Neoplasms
The therapeutic benefits of heme oxygenase (HO-1) inhibition in the management of systemic malignancies besides hepatocellular carcinomas.
Neoplasms
Therapeutic benefit of mesenchymal stem cells in pregnant rats with angiotensin receptor agonistic autoantibody-induced hypertension: Implications for immunomodulation and cytoprotection.
Neoplasms
Thiamine Alleviates High-Concentrate-Diet-Induced Oxidative Stress, Apoptosis, and Protects the Rumen Epithelial Barrier Function in Goats.
Neoplasms
Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation.
Neoplasms
tissue- and dose-dependent alteration of stress-inducible proteins by beta2-adrenoceptor agonist, salbutamol, in rats.
Neoplasms
TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells.
Neoplasms
Topical application of substance P promotes wound healing in streptozotocin-induced diabetic rats.
Neoplasms
Trans-chalcone added in topical formulation inhibits skin inflammation and oxidative stress in a model of ultraviolet B radiation skin damage in hairless mice.
Neoplasms
Transcriptional Changes after Enniatins A, A1, B and B1 Ingestion in Rat Stomach, Liver, Kidney and Lower Intestine.
Neoplasms
Transcriptome analysis of human cancer reveals a functional role of Heme Oxygenase-1 in tumor cell adhesion.
Neoplasms
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation.
Neoplasms
Trimetallic Nitride Endohedral Fullerenes Carboxyl-Gd3N@C80: A New Theranostic Agent for Combating Oxidative Stress and Resolving Inflammation.
Neoplasms
Tumor necrosis factor alpha acceleration of inflammatory responses by down-regulating heme oxygenase 1 in human peripheral monocytes.
Neoplasms
Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model.
Neoplasms
Typical airborne quinones modulate oxidative stress and cytokine expression in lung epithelial A549 cells.
Neoplasms
Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP.
Neoplasms
Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells.
Neoplasms
Upregulation of Heme Oxygenase-1 as a Host Mechanism for Protection Against Nitric Oxide-Induced Damage in Human Renal Epithelial Cells.
Neoplasms
Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity.
Neoplasms
Versatile Nanodrugs Containing Glutathione and Heme Oxygenase 1 Inhibitors Enable Suppression of Antioxidant Defense System in a Two-Pronged Manner for Enhanced Photodynamic Therapy.
Neoplasms
Vitamin D exerts neuroprotection via SIRT1/nrf-2/ NF-kB signaling pathways against D-galactose-induced memory impairment in adult mice.
Neoplasms
Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice.
Neoplasms
Zinc at sub-cytotoxic concentrations induces heme oxygenase-1 expression in human cancer cells.
Neoplasms
Zinc Protoporphyrin Polymeric Nanoparticles: Potent Heme Oxygenase Inhibitor for Cancer Therapy.
Neoplasms
Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition.
Neoplasms
[Advances in studies on pharmacological action of main chemical constituent of Curcuma Zedoary in preventing in-stent restenosis].
Neoplasms
[Effect of alpha-zearalanol upon the expression of HO-1 gene and the cytosolic free calcium level in tumor necrosis factor alpha-stimulated human endothelial cell]
Neoplasms
[Effect of heme oxygenase 1 on the apoptosis of human degenerated nucleus pulposus cells induced by tumor necrosis factor ?].
Neoplasms
[Formula: see text], a Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-[Formula: see text]B.
Neoplasms
[Ligustrazine alleviates the tissue injury of the submandibular glands by enhanceing the antioxidant and anti-inflammatory effects in diabetic rats].
Neoplasms
[Role and mechanism of low-dose lipopolysaccharide-treated human periodontal ligament stem cells on the expression of macrophage pro-inflammatory factors].
Neoplasms
[The mechanisms of carbon monoxide inhalation on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide]
Neoplasms, Squamous Cell
Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin.
Nephritis
Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease.
Nephritis
Human heme oxygenase-1 deficiency presenting with hemolysis, nephritis, and asplenia.
Nephritis
Interactions between inducible nitric oxide synthase and heme oxygenase-1 in glomerulonephritis.
Nervous System Diseases
Characterization and heme oxygenase-1 content of extracellular vesicles in human biofluids.
Neuralgia
Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation.
Neuralgia
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Neuralgia
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain.
Neuralgia
Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain.
Neuralgia
Heme oxygenase-1 inducer and carbon monoxide-releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice.
Neuralgia
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Neuralgia
Pharmacological activation of heme oxygenase (HO)-1/carbon monoxide pathway prevents the development of peripheral neuropathic pain in Wistar rats.
Neuralgia
Spinal Heme Oxygenase-1 (HO-1) Exerts Antinociceptive Effects Against Neuropathic Pain in a Mouse Model of L5 Spinal Nerve Ligation.
Neuralgia
The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation.
Neuralgia
Treatment with 5-fluoro-2-oxindole Increases the Antinociceptive Effects of Morphine and Inhibits Neuropathic Pain.
Neuralgia
Treatment with a carbon monoxide-releasing molecule inhibits chronic inflammatory pain in mice: nitric oxide contribution.
Neuralgia
Treatment with Carbon Monoxide-Releasing Molecules and an HO-1 Inducer Enhances the Effects and Expression of µ-Opioid Receptors during Neuropathic Pain.
Neuralgia
Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation.
Neuralgia
Treatment With the Delta Opioid Agonist UFP-512 Alleviates Chronic Inflammatory and Neuropathic Pain: Mechanisms Implicated.
Neuritis
Heme oxygenase-1 in lesions of rat experimental autoimmune encephalomyelitis and neuritis.
Neuroblastoma
3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.
Neuroblastoma
Carvacrol Depends on Heme Oxygenase-1 (HO-1) to Exert Antioxidant, Anti-inflammatory, and Mitochondria-Related Protection in the Human Neuroblastoma SH-SY5Y Cells Line Exposed to Hydrogen Peroxide.
Neuroblastoma
Ferrearin C induces apoptosis via heme oxygenase-1 (HO-1) induction in neuroblastoma.
Neuroblastoma
Heme Oxygenase-1 May Affect Cell Signalling via Modulation of Ganglioside Composition.
Neuroblastoma
Magnolol protects against trimethyltin-induced neuronal damage and glial activation in vitro and in vivo.
Neuroblastoma
Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors.
Neuroblastoma
Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1.
Neuroblastoma
Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2-ARE pathway.
Neuroblastoma
Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells.
Neuroblastoma
Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.
Neuroblastoma
TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells.
Neuroblastoma
The Parkinson disease-associated A30P mutation stabilizes alpha-synuclein against proteasomal degradation triggered by heme oxygenase-1 over-expression in human neuroblastoma cells.
Neurodegenerative Diseases
Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage.
Neurodegenerative Diseases
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.
Neurodegenerative Diseases
CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes.
Neurodegenerative Diseases
Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1 - evidence for direct and indirect antioxidant actions of bilirubin.
Neurodegenerative Diseases
Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
Neurodegenerative Diseases
Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats.
Neurodegenerative Diseases
Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells.
Neurodegenerative Diseases
Heme catabolism and heme oxygenase in neurodegenerative disease.
Neurodegenerative Diseases
Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections.
Neurodegenerative Diseases
Heme oxygenase-1 in Alzheimer disease: a tribute to Moussa Youdim.
Neurodegenerative Diseases
High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3.
Neurodegenerative Diseases
Involvement of Heme Oxygenase-1 in Neuropsychiatric and Neurodegenerative Diseases.
Neurodegenerative Diseases
Is glial heme oxygenase-1 suppression in neurodegenerative disorders permissive for neural repair?
Neurodegenerative Diseases
KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells.
Neurodegenerative Diseases
Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease.
Neurodegenerative Diseases
Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau.
Neurodegenerative Diseases
Oxidative and nitrosative modifications of biliverdin reductase-a in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment.
Neurodegenerative Diseases
Protective effect of remote limb post conditioning via upregulation of heme oxygenase-1/BDNF pathway in rat model of cerebral ischemic reperfusion injury.
Neurodegenerative Diseases
Redox metals and oxidative abnormalities in human prion diseases.
Neurodegenerative Diseases
Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function.
Neurodegenerative Diseases
Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance.
Neurodegenerative Diseases
Serum heme oxygenase-1 levels are increased in Parkinson's disease but not in Alzheimer's disease.
Neurodegenerative Diseases
Strategic Timing of Glial HMOX1 Expression Results in Either Schizophrenia-Like or Parkinsonian Behavior in Mice.
Neurodegenerative Diseases
Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases.
Neuroectodermal Tumors, Primitive
Heme Oxygenase-1 Promoter Polymorphism is a Predictor of Disease Relapse in Pancreatic Neuroendocrine Tumors.
Neuroendocrine Tumors
Heme Oxygenase-1 Promoter Polymorphism is a Predictor of Disease Relapse in Pancreatic Neuroendocrine Tumors.
Neuroinflammatory Diseases
Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in A?1-42-Induced Mice.
Neuroinflammatory Diseases
Depression-like behaviors and heme oxygenase-1 are regulated by Lycopene in lipopolysaccharide-induced neuroinflammation.
Neuroinflammatory Diseases
Gedunin Inhibits Oligomeric A?1-42-Induced Microglia Activation Via Modulation of Nrf2-NF-?B Signaling.
Neuroinflammatory Diseases
Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation.
Neuroinflammatory Diseases
Heme Oxygenase-1 Induction by Carbon Monoxide Releasing Molecule-3 Suppresses Interleukin-1?-Mediated Neuroinflammation.
Neuroinflammatory Diseases
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier.
Neuroinflammatory Diseases
Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression.
Neuroinflammatory Diseases
Microsatellite polymorphism in haem oxygenase 1 gene promoter in multiple sclerosis.
Neuroinflammatory Diseases
Mitigation of Microglia-mediated Acute Neuroinflammation and Tissue Damage by Heme Oxygenase 1 in a Rat Spinal Cord Injury Model.
Neuroinflammatory Diseases
Neuroinflammation associates with antioxidant heme oxygenase-1 response throughout the brain in persons living with HIV.
Neuroinflammatory Diseases
Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation.
Neuroinflammatory Diseases
Protein network exploration prioritizes targets for modulating neuroinflammation in Parkinson's disease.
Neuroinflammatory Diseases
Regenerative Effects of Heme Oxygenase Metabolites on Neuroinflammatory Diseases.
Neuroinflammatory Diseases
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Neuroinflammatory Diseases
Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases.
Neuroinflammatory Diseases
The Natural Rotenoid Deguelin Ameliorates Diabetic Neuropathy by Decreasing Oxidative Stress and Plasma Glucose Levels in Rats via the Nrf2 Signalling Pathway.
Neuroinflammatory Diseases
The role of TLR4 and HO-1 in neuroinflammation after subarachnoid hemorrhage.
Neutropenia
Role of HMOX1 Promoter Genetic Variants in Chemoresistance and Chemotherapy Induced Neutropenia in Children with Acute Lymphoblastic Leukemia.
Nevus, Pigmented
Decreased heme oxygenase-1 expression distinguishes human melanomas from melanocytic nevi.
Non-alcoholic Fatty Liver Disease
Activation of the Hypoxia Inducible Factor 1? Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.
Non-alcoholic Fatty Liver Disease
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2?-ATF4 pathway.
Non-alcoholic Fatty Liver Disease
Characteristics of Heme Oxygenase-1 Expression in Rat Hepatocytes during the Development of Nonalcoholic Steatohepatitis.
Non-alcoholic Fatty Liver Disease
Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity.
Non-alcoholic Fatty Liver Disease
Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress.
Non-alcoholic Fatty Liver Disease
Heme oxygenase-1 gene promoter polymorphism and the risk of pediatric nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients.
Non-alcoholic Fatty Liver Disease
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Non-alcoholic Fatty Liver Disease
Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Reduced heme oxygenase-1 expression in steatotic livers infected with hepatitis C virus.
Non-alcoholic Fatty Liver Disease
SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Non-alcoholic Fatty Liver Disease
The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD.
Obesity
?-Tocopherol protects renal cells from nicotine- or oleic acid-provoked oxidative stress via inducing heme oxygenase-1.
Obesity
Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients.
Obesity
Butein induction of HO-1 by p38 MAPK/Nrf2 pathway in adipocytes attenuates high-fat diet induced adipose hypertrophy in mice.
Obesity
Chronic carbon monoxide treatment attenuates development of obesity and remodels adipocytes in mice fed a high-fat diet.
Obesity
Corrigendum to "Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients".
Obesity
Daily exercise prevents diastolic dysfunction and oxidative stress in a female mouse model of western diet induced obesity by maintaining cardiac heme oxygenase-1 levels.
Obesity
Diminished upregulation of visceral adipose heme oxygenase-1 correlates with waist-to-hip ratio and insulin resistance.
Obesity
EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels.
Obesity
Emerging roles of cadmium and heme oxygenase in type-2 diabetes and cancer susceptibility.
Obesity
HMOX1 as a marker of iron excess-induced adipose tissue dysfunction, affecting glucose uptake and respiratory capacity in human adipocytes.
Obesity
Identification and validation of novel adipokines released from primary human adipocytes.
Obesity
Increased heme-oxygenase 1 expression decreases adipocyte differentiation and lipid accumulation in mesenchymal stem cells via upregulation of the canonical Wnt signaling cascade.
Obesity
Inhalation of carbon monoxide is ineffective as a long-term therapy to reduce obesity in mice fed a high fat diet.
Obesity
Irisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1/adiponectin axis in diet-induced obese mice.
Obesity
Obesity, Oxidative Stress, and Their Effect on Serum Heme Oxygenase-1 Concentrations and Insulin in Children Aged 3 to 5 Years in a Pediatric Hospital of the Ministry of Health CDMX.
Obesity
Overexpressed human heme Oxygenase-1 decreases adipogenesis in pigs and porcine adipose-derived stem cells.
Obesity
Positive Effects of Heme Oxygenase Upregulation on Adiposity and Vascular Dysfunction: Gene Targeting vs. Pharmacologic Therapy.
Obesity
Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet.
Obesity
The heme oxygenase system rescues hepatic deterioration in the condition of obesity co-morbid with type-2 diabetes.
Obesity
The Pivotal Role of Adipocyte-Na K peptide in Reversing Systemic Inflammation in Obesity and COVID-19 in the Development of Heart Failure.
Obesity
The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD.
Obesity
Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance.
Obesity, Morbid
Impact of Bariatric Surgery on Heme Oxygenase-1, Inflammation, and Insulin Resistance in Morbid Obesity with Obstructive Sleep Apnea.
Ocular Hypertension
Hemin, an inducer of heme oxygenase-1, lowers intraocular pressure in rabbits.
Oligodendroglioma
Heme oxygenase (HO)-1 expressing macrophages/microglial cells accumulate during oligodendroglioma progression.
Oligodendroglioma
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells.
Oligodendroglioma
Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma.
Oligospermia
Heme oxygenase enzyme activity in seminal plasma of oligoasthenoteratozoospermic males with varicocele.
Oral Submucous Fibrosis
Augmented heme oxygenase-1 expression in areca quid chewing-associated oral submucous fibrosis.
Osteoarthritis
Alleviation of Cartilage Destruction by Sinapic Acid in Experimental Osteoarthritis.
Osteoarthritis
Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1.
Osteoarthritis
Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis.
Osteoarthritis
Comparative study of HO-1 expressing synovial lining cells between RA and OA.
Osteoarthritis
Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes.
Osteoarthritis
Local gene delivery of heme oxygenase-1 by adeno-associated virus into osteoarthritic mouse joints exhibiting synovial oxidative stress.
Osteoarthritis
Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model.
Osteolysis
Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1.
Osteosarcoma
Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2.
Osteosarcoma
Bioinformatics analysis of microarray data to explore the key genes involved in HSF4 mutation-induced cataract.
Osteosarcoma
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Osteosarcoma
Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells to arsenic trioxide.
Osteosarcoma
Molecular Changes Induced in Rat Liver by Hemorrhage and Effects of Melanocortin Treatment.
Ototoxicity
Curcuma Longa (Curcumin) Decreases In Vivo Cisplatin-Induced Ototoxicity Through Heme Oxygenase-1 Induction.
Out-of-Hospital Cardiac Arrest
PLASMA HEME OXYGENASE-1 IN PATIENTS RESUSCITATED FROM OUT-OF-HOSPITAL CARDIAC ARREST.
Ovarian Neoplasms
Clinical significance of M2 macrophages expressing heme oxygenase-1 in malignant transformation of ovarian endometrioma.
Ovarian Neoplasms
Comparison of redox parameters in ovarian endometrioma and its malignant transformation.
Ovarian Neoplasms
Suppression of annexin A11 in ovarian cancer: implications in chemoresistance.
Pancreatic Neoplasms
Chlorophyll-Mediated Changes in the Redox Status of Pancreatic Cancer Cells Are Associated with Its Anticancer Effects.
Pancreatic Neoplasms
Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition.
Pancreatic Neoplasms
Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells.
Pancreatic Neoplasms
Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer.
Pancreatic Neoplasms
Heme oxygenase-1 germ line GTn promoter polymorphism is an independent prognosticator of tumor recurrence and survival in pancreatic cancer.
Pancreatic Neoplasms
Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder.
Pancreatic Neoplasms
Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment.
Pancreatic Neoplasms
JNK inhibition blocks piperlongumine-induced cell death and transcriptional activation of heme oxygenase-1 in pancreatic cancer cells.
Pancreatic Neoplasms
The inhibition of heme oxygenase-1 enhances the chemosensitivity and suppresses the proliferation of pancreatic cancer cells through the SHH signaling pathway.
Pancreatitis
Biliary tract external drainage protects against multiple organs injuries of severe acute pancreatitis rats via heme oxygenase-1 upregulation.
Pancreatitis
Eff ects of hemin, a heme oxygenase-1 inducer in L-arginine-induced acute pancreatitis and associated lung injury in adult male albino rats.
Pancreatitis
Expression of oxidative stress-responsive genes and cytokine genes during caerulein-induced acute pancreatitis.
Pancreatitis
Expression of stress proteins heme oxygenase-1 and -2 in acute pancreatitis and pancreatic islet betaTC3 and acinar AR42J cells.
Pancreatitis
Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.
Pancreatitis
Heme Oxygenase 1-Generated Carbon Monoxide and Biliverdin Attenuate the Course of Experimental Necrotizing Pancreatitis.
Pancreatitis
Heme Oxygenase-1 Gene Promoter Polymorphism Is Associated With the Development of Necrotizing Acute Pancreatitis.
Pancreatitis
Heme oxygenase-1 induced by desoxo-narchinol-A attenuated the severity of acute pancreatitis via blockade of neutrophil infiltration.
Pancreatitis
Heme Oxygenase-1 Polymorphism Is Associated With the Development of Necrotic Acute Pancreatitis Via Vascular Cell Adhesion Molecule-1 and the E-Selectin Expression Regulation Pathway.
Pancreatitis
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction.
Pancreatitis
Induction of heme oxygenase-1 improves the survival of pancreas grafts by prevention of pancreatitis after transplantation.
Pancreatitis
Metallothionein protects against cerulein-induced acute pancreatitis: analysis using transgenic mice.
Pancreatitis
Protective Effect of Adenoviral Transfer of Heme Oxygenase-1 Gene on Rats With Severe Acute Pancreatitis.
Pancreatitis
Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-? and augmentation of interleukin-10.
Pancreatitis
Shenmai Injection Upregulates Heme Oxygenase-1 to Confer Protection Against Severe Acute Pancreatitis.
Pancreatitis, Graft
Induction of heme oxygenase-1 improves the survival of pancreas grafts by prevention of pancreatitis after transplantation.
Paralysis
Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.
Paralysis
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Paraparesis
Vascular insult accompanied by overexpressed heme oxygenase-1 as a pathophysiological mechanism in experimental neurolathyrism with hind-leg paraparesis.
Parasitemia
Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice.
Parathyroid Neoplasms
Gene identification of potential malignant parathyroid tumors phenotype in Chinese population.
Parkinson Disease
A polymorphism located at an ATG transcription start site of the heme oxygenase-2 gene is associated with classical Parkinson's disease.
Parkinson Disease
An association study between Heme oxygenase-1 genetic variants and Parkinson's disease.
Parkinson Disease
Association between a heme oxygenase-2 genetic variant and risk of Parkinson's disease in Han Chinese.
Parkinson Disease
Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson's Disease.
Parkinson Disease
Differences in vulnerability of neurons and astrocytes to heme oxygenase-1 modulation: Implications for mitochondrial ferritin.
Parkinson Disease
Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1.
Parkinson Disease
Elevated Heme Oxygenase-1 Correlates With Increased Brain Iron Deposition Measured by Quantitative Susceptibility Mapping and Decreased Hemoglobin in Patients With Parkinson's Disease.
Parkinson Disease
Elevation of heme oxygenase-1 by proteasome inhibition affords dopaminergic neuroprotection.
Parkinson Disease
Evaluation of salivary heme oxygenase-1 as a potential biomarker of early Parkinson's disease.
Parkinson Disease
Genetic analysis of heme oxygenase-1 (HO-1) in German Parkinson's disease patients.
Parkinson Disease
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Parkinson Disease
Heme Oxygenase 1 and 2 Common Genetic Variants and Risk for Essential Tremor.
Parkinson Disease
Increased Plasma Heme Oxygenase-1 Levels in Patients With Early-Stage Parkinson's Disease.
Parkinson Disease
Interaction between heme oxygenase-1 genotypes and exposure to pesticides in Parkinson's disease.
Parkinson Disease
Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease.
Parkinson Disease
Neuroprotective effect of Annona muricata-derived polysaccharides in neuronal HT22 cell damage induced by hydrogen peroxide.
Parkinson Disease
Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia.
Parkinson Disease
Oxidative Stress Indices in Parkinson's Disease : Biochemical Determination.
Parkinson Disease
P450 and heme oxygenase enzymes in the basal ganglia and their roles in Parkinson's disease.
Parkinson Disease
Parkinson's disease: Alpha synuclein, heme oxygenase and biotherapeutic countermeasures.
Parkinson Disease
Protective effects of Nrf2-ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1.
Parkinson Disease
Serum heme oxygenase-1 levels are increased in Parkinson's disease but not in Alzheimer's disease.
Parkinson Disease
Strategic Timing of Glial HMOX1 Expression Results in Either Schizophrenia-Like or Parkinsonian Behavior in Mice.
Parkinson Disease
Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases.
peptide-methionine (r)-s-oxide reductase deficiency
Methionine sulfoxide reductase B3 deficiency stimulates heme oxygenase-1 expression via ROS-dependent and Nrf2 activation pathways.
Peri-Implantitis
Altered immunolocalization of heat-shock proteins in human peri-implant gingiva.
Periodontitis
Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells.
Periodontitis
Molecular docking study and antireabsorptive activity of a semi-synthetic coumarin derivative from Platymiscium floribundum in the ligature-induced periodontitis in rats: the involvement of heme oxygenase-1.
Periodontitis
Simultaneous Quantitative Analysis of Ginsenosides Isolated from the Fruit of Panax ginseng C.A. Meyer and Regulation of HO-1 Expression through EGFR Signaling Has Anti-Inflammatory and Osteogenic Induction Effects in HPDL Cells.
Periodontitis
Strontium Ranelate Elevates Expression of Heme Oxygenase-1 and Decreases Alveolar Bone Loss in Rats.
Periodontitis
Visualization of Oxidative Stress Induced by Experimental Periodontitis in Keap1-Dependent Oxidative Stress Detector-Luciferase Mice.
Peripheral Arterial Disease
Plasma heme oxygenase-1 is decreased in peripheral artery disease patients.
Peripheral Arterial Disease
Plasma Heme Oxygenase-1 Levels in Patients with Coronary and Peripheral Artery Diseases.
Peripheral Nervous System Diseases
Effects of Immunocytokine Combined with Cattle Encephalon Glycoside and Ignotin on CTGF, HO-1 and NT-3 in Patients with Type 2 Diabetic Peripheral Neuropathy.
Peripheral Nervous System Diseases
Heme oxygenase-1 inhibits neuropathic pain in rats with diabetic mellitus.
Peripheral Nervous System Diseases
Heme oxygenase-1, a novel target for the treatment of diabetic complications: focus on diabetic peripheral neuropathy.
Peripheral Vascular Diseases
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Peritonitis
Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.
Peritonitis
Role of heme oxygenase-1 in potentiation of phagocytic activity of macrophages by taurine chloramine: Implications for the resolution of zymosan A-induced murine peritonitis.
Persistent Infection
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Pheochromocytoma
Nerve growth factor induces anti-apoptotic heme oxygenase-1 in rat pheochromocytoma PC12 cells.
Pheochromocytoma
The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection.
Photosensitivity Disorders
Increased transcription and translation of heme oxygenase in Chinese hamster fibroblasts following photodynamic stress or Photofrin II incubation.
Photosensitivity Disorders
The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells.
Pick Disease of the Brain
Evidence for oxidative stress in Pick disease and corticobasal degeneration.
Plague
Activation of heme oxygenase expression by cobalt protoporphyrin treatment prevents pneumonic plague caused by inhalation of Yersinia pestis.
Pneumonia
Andrographolide protects against cigarette smoke-induced lung inflammation through activation of heme oxygenase-1.
Pneumonia
CO-Releasing Molecule-2 Induces Nrf2/ARE-Dependent Heme Oxygenase-1 Expression Suppressing TNF-?-Induced Pulmonary Inflammation.
Pneumonia
Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia.
Pneumonia
Heme oxygenase-1 attenuates acute pulmonary inflammation by decreasing the release of segmented neutrophils from the bone marrow.
Pneumonia
Heme oxygenase-1 induction by rosiglitazone via PKC?/AMPK?/p38 MAPK?/SIRT1/PPAR? pathway suppresses lipopolysaccharide-mediated pulmonary inflammation.
Pneumonia
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection.
Pneumonia
Heme Oxygenase-1-Expressing Dendritic Cells Promote Foxp3+ Regulatory T Cell Differentiation and Induce Less Severe Airway Inflammation in Murine Models.
Pneumonia
Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups
Pneumonia
Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups.
Pneumonia
Peroxisome proliferator activated receptor-{gamma} (PPAR{gamma}) ligands induce heme oxygenase-1 in lung fibroblasts by a PPAR{gamma}-independent, glutathione-dependent mechanism.
Pneumonia
PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice.
Pneumonia
Protection against ozone-induced pulmonary inflammation and cell death by endotoxin pretreatment in mice: role of HO-1.
Pneumonia
Pseudomonas aeruginosa-induced neutrophilic lung inflammation is attenuated by adenovirus-mediated transfer of the heme oxygenase 1 cDNA in mice.
Pneumonia
Tissue heme oxygenase-1 exerts anti-inflammatory effects on LPS-induced pulmonary inflammation.
Pneumonia
TLR4 signaling-induced heme oxygenase upregulation in the acute lung injury: role in hemorrhagic shock and two-hit induced lung inflammation.
Pneumonia
Usefulness of Intratracheal Instillation Studies for Estimating Nanoparticle-Induced Pulmonary Toxicity.
Pneumothorax
Induction of heme oxygenase-1, biliverdin reductase and H-ferritin in lung macrophage in smokers with primary spontaneous pneumothorax: role of HIF-1alpha.
Polycystic Ovary Syndrome
Association of heme oxygenase-1 with the risk of polycystic ovary syndrome in non-obese women.
Porcine Reproductive and Respiratory Syndrome
Heme oxygenase-1 acts as an antiviral factor for porcine reproductive and respiratory syndrome virus infection and over-expression inhibits virus replication in vitro.
Porcine Reproductive and Respiratory Syndrome
Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication.
Porcine Reproductive and Respiratory Syndrome
Inhibition of replication of porcine reproductive and respiratory syndrome virus by hemin is highly dependent on heme oxygenase-1, but independent of iron in MARC-145 cells.
Porcine Reproductive and Respiratory Syndrome
MiR-24-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication through Suppression of Heme Oxygenase-1 Expression.
Porphyria, Acute Intermittent
Effect of the heme oxygenase inducer hemin on blood haemostasis measured by high-frequency ultrasound.
Porphyrias
Stimulation of liver heme oxygenase in hexachlorobenzene-induced hepatic porphyria.
Porphyrias, Hepatic
Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria.
Porphyrias, Hepatic
Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications.
Porphyrias, Hepatic
Stimulation of liver heme oxygenase in hexachlorobenzene-induced hepatic porphyria.
Porphyrias, Hepatic
Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria.
Pre-Eclampsia
Activation of HO-1 protects placental cells function in oxidative stress via regulating ZO-1/occludin.
Pre-Eclampsia
Cellular mRNA expressions of anti-oxidant factors in the blood of preeclamptic women.
Pre-Eclampsia
Circulating Heme Oxygenase-1: Not a Predictor of Preeclampsia but Highly Expressed in Pregnant Women Who Subsequently Develop Severe Preeclampsia.
Pre-Eclampsia
Circulating HO-1 levels are not associated with plasma sFLT-1 and GTn HMOX1 polymorphism in preeclampsia.
Pre-Eclampsia
Decidual expression and maternal serum levels of heme oxygenase 1 are increased in pre-eclampsia.
Pre-Eclampsia
Decreased Lectin-Like Oxidized LDL Receptor 1 (LOX-1) and Low Nrf2 Activation in Placenta Are Involved in Preeclampsia.
Pre-Eclampsia
Differential Expression of HSP90? and Heme oxygenase in cord blood RBC during preeclampsia.
Pre-Eclampsia
Effects of Nrf-2 expression in trophoblast cells and vascular endothelial cells in preeclampsia.
Pre-Eclampsia
Expression of placenta growth factor, soluble fms-like tyrosine kinase-1, metal-responsive transcription factor-1, heme oxygenase 1 and hypoxia inducible factor-1? mRNAs in pre-eclampsia placenta and the effect of pre-eclampsia sera on their expression of choriocarcinoma cells.
Pre-Eclampsia
Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia.
Pre-Eclampsia
Fourteen years of debate and workshops on the immunology of preeclampsia. Where are we now after the 2012 workshop?
Pre-Eclampsia
Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction.
Pre-Eclampsia
HMOX1 is partly responsible for phenotypic and functional abnormalities in mesenchymal stem cells/stromal cells from placenta of preeclampsia (PE) patients.
Pre-Eclampsia
Immunohistochemical localization of heme oxygenase-1 and bilirubin/biopyrrin of heme metabolites as antioxidants in human placenta with preeclampsia.
Pre-Eclampsia
Increased Heme Oxygenase-1 and Nuclear Factor Erythroid 2-Related Factor-2 in the Placenta Have a Cooperative Action on Preeclampsia.
Pre-Eclampsia
Increased serum heme oxygenase-1 levels as a diagnostic marker of oxidative stress in preeclampsia.
Pre-Eclampsia
Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in Preeclampsia.
Pre-Eclampsia
Investigation heme oxygenase-1 polymorphism with the pathogenesis of preeclampsia.
Pre-Eclampsia
Involvement of the heme oxygenase system in the development of preeclampsia and as a possible therapeutic target.
Pre-Eclampsia
Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1.
Pre-Eclampsia
Maternal Heme Oxygenase 1 Regulates Placental Vasculature Development via Angiogenic Factors in Mice.
Pre-Eclampsia
Microsatellite polymorphism in the heme oxygenase-1 promoter is associated with nonsevere and late-onset preeclampsia.
Pre-Eclampsia
Monocytes from preeclamptic women previously treated with silibinin attenuate oxidative stress in human endothelial cells.
Pre-Eclampsia
MZe786 Rescues Cardiac Mitochondrial Activity in High sFlt-1 and Low HO-1 Environment.
Pre-Eclampsia
MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment.
Pre-Eclampsia
OS 21-05 PIVOTAL ROLE OF HEME OXYGENASE IN AMELIORATION BY NICOTINAMIDE OF FETAL GROWTH RESTRICTION ASSOCIATED WITH PREECLAMPSIA.
Pre-Eclampsia
Overexpressed HO-1 is associated with reduced STAT3 activation in preeclampsia placenta and inhibits STAT3 phosphorylation in placental JEG-3 cells under hypoxia.
Pre-Eclampsia
Peroxisome Proliferator-Activated Receptor-{gamma} as a Potential Therapeutic Target in the Treatment of Preeclampsia.
Pre-Eclampsia
Resveratrol improves endothelial cell markers impaired by plasma incubation from women who subsequently develop preeclampsia.
Pre-Eclampsia
Serum heme oxygenase 1 (HO-1), soluble FMS like tyrosine kinase (sFlt-1) level, and neonatal outcome in early onset, late onset preeclampsia, and normal pregnancy.
Pre-Eclampsia
Sofalcone Upregulates the Nuclear Factor (Erythroid-Derived 2)-Like 2/Heme Oxygenase-1 Pathway, Reduces Soluble fms-Like Tyrosine Kinase-1, and Quenches Endothelial Dysfunction: Potential Therapeutic for Preeclampsia.
Pre-Eclampsia
The hemoglobin degradation pathway in patients with preeclampsia - Fetal hemoglobin, heme, heme oxygenase-1 and hemopexin - Potential diagnostic biomarkers?
Pre-Eclampsia
Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Overexpression of heme oxygenase-1 in microenvironment mediates vincristine resistance of B-cell acute lymphoblastic leukemia by promoting vascular endothelial growth factor secretion.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Role of HMOX1 Promoter Genetic Variants in Chemoresistance and Chemotherapy Induced Neutropenia in Children with Acute Lymphoblastic Leukemia.
Pregnancy Complications
Heme oxygenase as a therapeutic target in immunological pregnancy complications.
Premature Birth
Expression of Heme Oxygenase-1 and Leukemia Inhibitory Factor in Maternal Plasma and Placental Tissue in a Lipopolysaccharide-Induced Late Pregnancy Preterm Birth Mouse Model.
Priapism
Expression and activity of heme oxygenase-1 in artificially induced low-flow priapism in rat penile tissues.
Priapism
Second Pathways in the Pathophysiology of Ischemic Priapism and Treatment Alternatives.
Primary Ovarian Insufficiency
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
Prostatic Hyperplasia
Correlation between lipid profile and heme oxygenase system in patients with benign prostatic hyperplasia.
Prostatic Hyperplasia
Heme oxygenase levels and metaflammation in benign prostatic hyperplasia patients.
Prostatic Neoplasms
Association of HO-1 and BRCA1 Is Critical for the Maintenance of Cellular Homeostasis in Prostate Cancer.
Prostatic Neoplasms
Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: nuclear HO-1 promotes vascular endothelial growth factor secretion.
Prostatic Neoplasms
Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells.
Prostatic Neoplasms
Exosomes Promote the Transition of Androgen-Dependent Prostate Cancer Cells into Androgen-Independent Manner Through Up-Regulating the Heme Oxygenase-1.
Prostatic Neoplasms
Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer.
Prostatic Neoplasms
Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer.
Prostatic Neoplasms
Heme oxygenase-1 (HO-1) expression in prostate cancer cells modulates the oxidative response in bone cells.
Prostatic Neoplasms
Heme oxygenase-1 in the forefront of a multi-molecular network that governs cell-cell contacts and filopodia-induced zippering in prostate cancer.
Prostatic Neoplasms
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.
Prostatic Neoplasms
Heme Oxygenase-1 Is a Pivotal Modulator of Bone Turnover and Remodeling: Molecular Implications for Prostate Cancer Bone Metastasis.
Prostatic Neoplasms
Hemin activation abrogates Mycoplasma hyorhinis replication in chronically infected prostate cancer cells via heme oxygenase-1 induction.
Prostatic Neoplasms
HO-1 Interactors Involved in the Colonization of the Bone Niche: Role of ANXA2 in Prostate Cancer Progression.
Prostatic Neoplasms
In Vivo Hemin Conditioning Targets the Vascular and Immunologic Compartments and Restrains Prostate Tumor Development.
Prostatic Neoplasms
Induction of heme oxygenase-1 with hemin alleviates cisplatin-induced reproductive toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line.
Prostatic Neoplasms
Inhibition of NF-?B nuclear translocation via HO-1 activation underlies ?-tocopheryl succinate toxicity.
Prostatic Neoplasms
PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome.
Protein-Energy Malnutrition
Chemical pathology of homocysteine. V. Thioretinamide, thioretinaco, and cystathionine synthase function in degenerative diseases.
Proteinuria
Glomerular Epithelial Cells-Targeted Heme Oxygenase-1 Over Expression in the Rat: Attenuation of Proteinuria in Secondary But Not Primary Injury.
Proteinuria
Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells.
Proteinuria
Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis.
Proteinuria
Increased serum heme oxygenase-1 levels as a diagnostic marker of oxidative stress in preeclampsia.
Proteinuria
Proteinuria as a determinant of renal expression of heme oxygenase-1: studies in models of glomerular and tubular proteinuria in the rat.
Protozoan Infections
Heme oxygenase-1 in protozoan infections: A tale of resistance and disease tolerance.
Pseudorabies
The Cytoprotective Enzyme Heme Oxygenase-1 Suppresses Pseudorabies Virus Replication in vitro.
Psoriasis
Cogent differences in skin heme oxygenase-1 levels between psoriasis patients and healthy controls.
Psoriasis
Microsatellite polymorphism in the heme oxygenase-1 gene promoter and the risk of psoriasis in Taiwanese.
Psoriasis
Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment.
Psoriasis
Pathophysiological Alterations of Redox Signaling and Endocannabinoid System in Granulocytes and Plasma of Psoriatic Patients.
Pulmonary Arterial Hypertension
Activation of PPAR-? ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21(WAF1): an in vivo study in rats.
Pulmonary Arterial Hypertension
Erythropoietin Attenuates Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension through Interplay between Endothelial Progenitor Cells and Heme Oxygenase.
Pulmonary Arterial Hypertension
[Genistein attenuates monocrotaline-induced pulmonary arterial hypertension in rats by up-regulating heme oxygenase-1 expression].
Pulmonary Disease, Chronic Obstructive
Association of lung function decline with the heme oxygenase-1 gene promoter microsatellite polymorphism in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France.
Pulmonary Disease, Chronic Obstructive
Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.
Pulmonary Disease, Chronic Obstructive
Decreased exercise-induced expression of NF-{kappa}B regulated genes in muscle of COPD patients.
Pulmonary Disease, Chronic Obstructive
Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae.
Pulmonary Disease, Chronic Obstructive
Effect of diesel exhaust generated by a city bus engine on stress responses and innate immunity in primary bronchial epithelial cell cultures.
Pulmonary Disease, Chronic Obstructive
Effect of heme oxygenase-1 polymorphisms on lung function and gene expression.
Pulmonary Disease, Chronic Obstructive
Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter.
Pulmonary Disease, Chronic Obstructive
Exogenous neutrophil elastase enters bronchial epithelial cells and suppresses cigarette smoke extract-induced heme oxygenase-1 by cleaving sirtuin 1.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphism of heme oxygenase 1 promoter in the occurrence and severity of chronic obstructive pulmonary disease: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Genetic variations in detoxification enzymes and HIF-1? in Japanese patients with COPD.
Pulmonary Disease, Chronic Obstructive
Heme oxygenase 1 polymorphism, occupational vapor, gas, dust, and fume exposure and chronic obstructive pulmonary disease in a Danish population-based study.
Pulmonary Disease, Chronic Obstructive
Heme oxygenase-1 induction attenuates senescence in chronic obstructive pulmonary disease lung fibroblasts by protecting against mitochondria dysfunction.
Pulmonary Disease, Chronic Obstructive
Heme oxygenase-1 polymorphism associated with severity of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Increased expression of heme oxygenase (HO)-1 in alveolar spaces and HO-2 in alveolar walls of smokers.
Pulmonary Disease, Chronic Obstructive
Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD.
Pulmonary Disease, Chronic Obstructive
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Pulmonary Disease, Chronic Obstructive
Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild-moderate ex-smoker COPD patients with persistent oxidative stress.
Pulmonary Disease, Chronic Obstructive
Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study.
Pulmonary Disease, Chronic Obstructive
Relationship between COPD and polymorphisms of HOX-1 and mEPH in a Chinese population.
Pulmonary Disease, Chronic Obstructive
Special issue on carbon monoxide and exhaled biomarkers in human disease.
Pulmonary Disease, Chronic Obstructive
Study on changes of heme oxygenase expression in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Update in chronic obstructive pulmonary disease: role of antioxidant and metabolizing gene polymorphisms.
Pulmonary Disease, Chronic Obstructive
[Association of lung function decline with the microsatellite polymorphism in the heme oxygenase-1 gene promoter, in a general population sample. Results from the Longitudinal European Community Respiratory Health Survey (ECRHS-France)]
Pulmonary Disease, Chronic Obstructive
[Genetic features during chronic obstructive pulmonary disease]
Pulmonary Edema
HMOX1 Promoter Microsatellite Polymorphism and High Altitude Pulmonary Edema in Han Chinese Men.
Pulmonary Edema
HMOX1 Promoter Microsatellite Polymorphism Is Not Associated With High Altitude Pulmonary Edema in Han Chinese.
Pulmonary Embolism
Left atrial myxoma presenting as pulmonary embolism: potential role of heme oxygenase-1.
Pulmonary Embolism
Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.
Pulmonary Embolism
Rapid clearance of circulating haptoglobin from plasma during acute pulmonary embolism in rats results in HMOX1 up-regulation in peripheral blood leukocytes.
Pulmonary Embolism
[Molecular biologic study on heme oxygenase in experiment pulmonary thromboembolism]
Pulmonary Emphysema
Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lungs attenuates elastase-induced pulmonary emphysema in mice.
Pulmonary Emphysema
[Etiology, pathogenesis and management of senile inflammatory pulmonary diseases]
Pulmonary Fibrosis
Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway.
Pulmonary Fibrosis
Attenuation of bleomycin induced pulmonary fibrosis in mice using the heme oxygenase inhibitor Zn-deuteroporphyrin IX-2,4-bisethylene glycol.
Pulmonary Fibrosis
Beneficial effects of early (but not late) intervention of heme oxygenase-1 on bleomycin-induced pulmonary fibrosis in mice.
Pulmonary Fibrosis
Change of heme oxygenase-1 expression in lung injury induced by chrysotile asbestos in vivo and in vitro.
Pulmonary Fibrosis
Expression of heme oxygenase-1 in the lungs of rats exposed to crocidolite asbestos.
Pulmonary Fibrosis
Expression of heme oxygenase-1 in the lungs of rats exposed to crystalline silica.
Pulmonary Fibrosis
Expression of heme oxygenase-1 in the lungs of rats exposed to potassium octatitanate whiskers.
Pulmonary Fibrosis
Transforming growth factor ß inhibits heme oxygenase-1 expression in lung fibroblast through NF-B dependent pathway.
Purpura, Thrombocytopenic, Idiopathic
Human spleen heme oxygenase and microsomal electron transport system component activity in normals and in patients with hemolytic anemia, idiopathic thrombocytopenic purpura, and lymphoproliferative disorders.
Purpura, Thrombocytopenic, Idiopathic
Human spleen heme oxygenase in normal, hemolytic and other pathological states.
Pyloric Stenosis, Hypertrophic
Distribution of heme oxygenase-2 in nerves and interstitial cells of Cajal in the normal pylorus and in infantile hypertrophic pyloric stenosis.
Relative Energy Deficiency in Sport
Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis.
Renal Insufficiency
Heme oxygenase-1 induction improves ischemic renal failure: role of nitric oxide and peroxynitrite.
Renal Insufficiency
Low serum bilirubin in chronic renal failure. Relation to haem metabolism.
Renal Insufficiency
Rokumi-jio-gan-Containing Prescriptions Attenuate Oxidative Stress, Inflammation, and Apoptosis in the Remnant Kidney.
Renal Insufficiency
Vascular function and arginine and dimethylarginines in gentamicin-induced renal failure: A possible effect of heme oxygenase-1 inducer hemin.
Renal Insufficiency, Chronic
A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1.
Renal Insufficiency, Chronic
Expression of HO-1 in chronic renal insufficiency. Rat kidney and implication.
Renal Insufficiency, Chronic
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Renal Insufficiency, Chronic
Hyperhomocysteinemia Accelerates Acute Kidney Injury to Chronic Kidney Disease Progression by Downregulating Heme Oxygenase-1 Expression.
Renal Insufficiency, Chronic
THE ASSOCIATION OF SERUM BILIRUBIN ON KIDNEY CLINICOPATHOLOGIC FEATURES AND RENAL OUTCOME IN PATIENTS WITH DIABETIC NEPHROPATHY: A BIOPSY-BASED STUDY.
Renal Insufficiency, Chronic
Up-regulation of heme oxygenase-1 by celastrol alleviates oxidative stress and vascular calcification in chronic kidney disease.
Reperfusion Injury
A novel strategy against ischemia and reperfusion injury: cytoprotection with heme oxygenase system.
Reperfusion Injury
A Somatostatin Analogue, Octreotide, Ameliorates Intestinal Ischemia-Reperfusion Injury Through the Early Induction of Heme Oxygenase-1.
Reperfusion Injury
A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo.
Reperfusion Injury
Alleviating ischemia-reperfusion injury in aged rat liver by induction of heme oxygenase-1.
Reperfusion Injury
Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation.
Reperfusion Injury
Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice.
Reperfusion Injury
Cobalt-protoporphyrin induced heme oxygenase overexpression and its impact on liver regeneration.
Reperfusion Injury
Contributions of heme oxygenase-1 in postconditioning-protected ischemia-reperfusion injury in rat liver transplantation.
Reperfusion Injury
Curcumin induces heme oxygenase-1 in hepatocytes and is protective in simulated cold preservation and warm reperfusion injury.
Reperfusion Injury
Cytoprotective role of heme oxygenase-1 in liver ischemia reperfusion injury.
Reperfusion Injury
Deciphering the Role of Heme Oxygenase-1 (HO-1) Expressing Macrophages in Renal Ischemia-Reperfusion Injury.
Reperfusion Injury
Dobutamine improves liver function after hemorrhagic shock through induction of heme oxygenase-1.
Reperfusion Injury
Donor HO-1 expression inhibits intimal hyperplasia in unmanipulated graft recipients: a potential role for CD8+ T-cell modulation by carbon monoxide.
Reperfusion Injury
Dual protective role of HO-1 in transplanted liver grafts: a review of experimental and clinical studies.
Reperfusion Injury
Effect of heme oxygenase-1 on the protection of ischemia reperfusion injury of bile duct in rats after liver transplantation.
Reperfusion Injury
Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury.
Reperfusion Injury
Heme oxygenase 1 and renal ischemia and reperfusion injury: The impact of immunosuppressive drug.
Reperfusion Injury
Heme oxygenase 1 and renal ischemia and reperfusion injury: the impact of immunosuppressive drug.
Reperfusion Injury
Heme oxygenase 1 may mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats.
Reperfusion Injury
Heme Oxygenase Expression in Human Placental Villous Tissue in Response to Exposure to in vitro Ischemia-Reperfusion Injury.
Reperfusion Injury
Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation.
Reperfusion Injury
Heme Oxygenase-1 dictates innate - adaptive immune phenotype in human liver transplantation.
Reperfusion Injury
Heme oxygenase-1 gene expression in pericentral hepatocytes through beta1-adrenoceptor stimulation.
Reperfusion Injury
Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury.
Reperfusion Injury
Heme Oxygenase-1 in liver transplant ischemia-reperfusion injury: From bench-to-bedside.
Reperfusion Injury
Heme oxygenase-1 induced in muller cells plays a protective role in retinal ischemia-reperfusion injury in rats.
Reperfusion Injury
Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling.
Reperfusion Injury
Heme oxygenase-1 pathway is involved in delayed protection induced by heat stress against cardiac ischemia-reperfusion injury.
Reperfusion Injury
Heme oxygenase-1 protects donor livers from ischemia/reperfusion injury: the role of Kupffer cells.
Reperfusion Injury
Heme oxygenase-1: a redoubtable response that limits reperfusion injury in the transplanted adipose liver.
Reperfusion Injury
Heme oxygenase-1: An important therapeutic target for protecting against myocardial ischemia and reperfusion injury.
Reperfusion Injury
Hemin Preconditioning Upregulates Heme Oxygenase-1 in Deceased Donor Renal Transplant Recipients: A Randomized, Controlled, Phase IIB Trial.
Reperfusion Injury
Hemoglobin-based oxygen carrier induces heme oxygenase-1 in the heart and lung but not brain.
Reperfusion Injury
Hemoglobin-glutamer 200 reduces reperfusion injury of the cold preserved rat liver by induction of heme oxygenase-1.
Reperfusion Injury
Hepatic overexpression of heme oxygenase-1 improves liver allograft survival by expanding T regulatory cells.
Reperfusion Injury
Hepatocellular Heme Oxygenase-1: A Potential Mechanism of Erythropoietin-Mediated Protection after Liver Ischemia-Reperfusion Injury.
Reperfusion Injury
Higenamine reduces apoptotic cell death by induction of heme oxygenase-1 in rat myocardial ischemia-reperfusion injury.
Reperfusion Injury
Hyperbaric Oxygen Preconditioning Attenuates Myocardium Ischemia-Reperfusion Injury Through Upregulation of Heme Oxygenase 1 Expression: PI3K/Akt/Nrf2 Pathway Involved.
Reperfusion Injury
Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury.
Reperfusion Injury
Influence of heme oxygenase-1 on microcirculation after kidney transplantation.
Reperfusion Injury
Inhibition of dendritic cell maturation and function is independent of heme oxygenase 1 but requires the activation of STAT3.
Reperfusion Injury
Ischemic postconditioning attenuates lung reperfusion injury and reduces systemic proinflammatory cytokine release via heme oxygenase 1.
Reperfusion Injury
Ischemic preconditioning of small bowel mitigates the late phase of reperfusion injury: heme oxygenase mediates cytoprotection.
Reperfusion Injury
Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats.
Reperfusion Injury
Kupffer-cell specific induction of heme oxygenase 1 (hsp32) by the atrial natriuretic peptide--role of cGMP.
Reperfusion Injury
Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury.
Reperfusion Injury
Non-urate transporter 1, non-glucose transporter member 9-related renal hypouricemia and acute renal failure accompanied by hyperbilirubinemia after anaerobic exercise: a case report.
Reperfusion Injury
Pharmacological induction of heme oxygenase-1 inhibits iNOS and oxidative stress in renal ischemia-reperfusion injury.
Reperfusion Injury
Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats.
Reperfusion Injury
Pharmacological preconditioning of rat liver by up-regulation of heme oxygenase 1.
Reperfusion Injury
Pharmacological preconditioning with simvastatin protects liver from ischemia-reperfusion injury by heme oxygenase-1 induction.
Reperfusion Injury
PLASMA HEME OXYGENASE-1 IN PATIENTS RESUSCITATED FROM OUT-OF-HOSPITAL CARDIAC ARREST.
Reperfusion Injury
Possible role of garlic oil in ameliorating renal injury after liver ischemia/reperfusion in rats.
Reperfusion Injury
Preconditioning donor liver with Nodosin perfusion lessens rat ischemia reperfusion injury via heme oxygenase-1 upregulation.
Reperfusion Injury
Preconditioning with Hyperbaric Oxygen Induces Tolerance Against Renal Ischemia-Reperfusion Injury Via Increased Expression of Heme Oxygenase-1.
Reperfusion Injury
Prior induction of heme oxygenase-1 with glutathione depletor ameliorates the renal ischemia and reperfusion injury in the rat.
Reperfusion Injury
Propofol vs desflurane on the cytokine, matrix metalloproteinase-9, and heme oxygenase-1 response during living donor liver transplantation: A pilot study.
Reperfusion Injury
Protective effect of artemisia asiatica extract against renal ischemia-reperfusion injury in mice.
Reperfusion Injury
Protective effect of heme oxygenase-1 on hepatic ischemia-reperfusion injury through inhibition of platelet adhesion to the sinusoids.
Reperfusion Injury
Protective effect of ischemic postconditioning on lung ischemia-reperfusion injury in rats and the role of heme oxygenase-1.
Reperfusion Injury
Protective effects of adiponectin against renal ischemia-reperfusion injury via prostacyclin -PPAR?- heme oxygenase-1 signaling pathway.
Reperfusion Injury
Protective effects of heme oxygenase 1 during ischemia-reperfusion injury: Hepatocytes or non-parenchymal cells?
Reperfusion Injury
Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats.
Reperfusion Injury
Protective role of heme oxygenase-1 in fatty liver ischemia-reperfusion injury.
Reperfusion Injury
Rapid ventricular pacing-induced postconditioning attenuates reperfusion injury: effects on peroxynitrite, RISK and SAFE pathways.
Reperfusion Injury
Remote pharmacological preconditioning on median nerve territory increases Hsp32 expression and attenuates ischemia-reperfusion injury in rat heart.
Reperfusion Injury
Reply to: "Protective effects of heme oxygenase 1 during ischemia-reperfusion injury: Hepatocytes or non parenchymal cells?"
Reperfusion Injury
Retinal protection from acute glaucoma-induced ischemia-reperfusion injury through pharmacological induction of Heme oxygenase-1 by Cobalt protoporphyrin.
Reperfusion Injury
Role of heme oxygenase-1/carbon monoxide system in pulmonary ischemia-reperfusion injury.
Reperfusion Injury
Sequence of reperfusion influences ischemia/reperfusion injury and primary graft function following porcine liver transplantation.
Reperfusion Injury
Small Interfering RNA Targeting Heme Oxygenase-1 (HO-1) Reinforces Liver Apoptosis Induced by Ischemia-Reperfusion Injury in Mice: HO-1 Is Necessary for Cytoprotection.
Reperfusion Injury
Specific expression of heme oxygenase-1 by myeloid cells modulates renal ischemia-reperfusion injury.
Reperfusion Injury
Splenectomy ameliorates hepatic ischemia and reperfusion injury mediated by heme oxygenase-1 induction in the rat.
Reperfusion Injury
Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages.
Reperfusion Injury
Steroidal Saponin Diosgenin from Dioscorea bulbifera Protects Cardiac Cells from Hypoxia-reoxygenation Injury Through Modulation of Pro-survival and Pro-death Molecules.
Reperfusion Injury
Taxol prevents myocardial ischemia-reperfusion injury by inducing JNK-mediated HO-1 expression.
Reperfusion Injury
The role of heme oxygenase 1 in rapamycin-induced renal dysfunction after ischemia and reperfusion injury.
Reperfusion Injury
The role of nitric oxide synthase and heme oxygenase in the protective effect of hypothermia in ischemia-reperfusion injury.
Reperfusion Injury
Tissue-protective effect of glutamine on hepatic ischemia-reperfusion injury via induction of heme oxygenase-1.
Reperfusion Injury
Upregulation of heme oxygenase 1 (HO-1) attenuates kidney damage, oxidative stress and inflammatory reaction during renal ischemia/ reperfusion injury.
Reperfusion Injury
Upregulation of heme oxygenase-1 expression for protecting against myocardial ischemia and reperfusion injury.
Reperfusion Injury
Upregulation of heme oxygenase-1 protected against brain damage induced by transient cerebral ischemia-reperfusion injury in rats.
Reperfusion Injury
Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity.
Reperfusion Injury
[Effect of heme oxygenase on apoptosis and apoptosis genes in hepatic ischemia reperfusion injury in rats]
Reperfusion Injury
[Effect of Shenmai injection on expression and activity of heme oxygenase-1 in reperfusion injury after pulmonary ischemia in rabbits]
Reperfusion Injury
[Effects of ischemic postconditioning on the expression of heme oxygenase-1 in the liver graft with ischemia and reperfusion injury in rats]
Reperfusion Injury
[Gene transfer-induced human heme oxygenase-1 over-expression protects kidney from ischemia-reperfusion injury in rats].
Reperfusion Injury
[Involvement of potassium channel in hemin-induced cardioprotection in rat hearts]
Reperfusion Injury
[L-glutamine-induced heme oxygenase-1 protects small intestine from warm ischemia and reperfusion injury in the rat]
Reperfusion Injury
[Protective effect of heme oxygenase on hepatic ischemia reperfusion injury in rats.]
Respiratory Distress Syndrome
Diannexin Can Ameliorate Acute Respiratory Distress Syndrome in Rats by Promoting Heme Oxygenase-1 Expression.
Respiratory Distress Syndrome
Genetic Contributions to the Development of Complications in Preterm Newborns.
Respiratory Distress Syndrome
Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome.
Respiratory Distress Syndrome
Heme oxygenase-1 participates in the resolution of seawater drowning-induced acute respiratory distress syndrome.
Respiratory Distress Syndrome
Hepatocyte growth factor prevents multiple organ injuries in endotoxemic mice through a heme oxygenase-1-dependent mechanism.
Respiratory Distress Syndrome
Increased heme oxygenase-1 expression in premature infants with respiratory distress syndrome.
Respiratory Distress Syndrome
Inducible nitric oxide synthase and heme oxygenase-1 in the lung during lipopolysaccharide tolerance and cross tolerance.
Respiratory Distress Syndrome
Is carbon monoxide-mediated cyclic guanosine monophosphate production responsible for low blood pressure in neonatal respiratory distress syndrome?
Respiratory Distress Syndrome
Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome.
Respiratory Distress Syndrome
Serum heme oxygenase-1 measurement is useful for evaluating disease activity and outcomes in patients with acute respiratory distress syndrome and acute exacerbation of interstitial lung disease.
Respiratory Distress Syndrome
[Changes of carbon monoxide, nitric oxide levels and heme oxygenase system in acute respiratory distress syndrome induced by oleic acid]
Respiratory Distress Syndrome
[Preventive effects and mechanism of heme oxygenase-1 activation on acute respiratory distress syndrome in rats]
Respiratory Insufficiency
Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation.
Restless Legs Syndrome
Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome.
Restless Legs Syndrome
Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Restless Legs Syndrome.
Retinal Degeneration
High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3.
Retinal Degeneration
Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration.
Retinal Detachment
Viral delivery of heme oxygenase-1 attenuates photoreceptor apoptosis in an experimental model of retinal detachment.
Retinoblastoma
Heme oxygenase: expression in human retina and modulation by stress agents in a human retinoblastoma cell model system.
Retinopathy of Prematurity
Genetic Contributions to the Development of Complications in Preterm Newborns.
Rhabdomyolysis
Can gas replace protein function? CO abrogates the oxidative toxicity of myoglobin.
Rhabdomyolysis
Heme oxygenase activity and some indices of antioxidant protection in rat liver and kidney in glycerol model of rhabdomyolysis.
Rhabdomyolysis
Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat.
Rhabdomyolysis
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury.
Rhabdomyosarcoma
Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma.
Rheumatic Diseases
Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases.
Rheumatic Diseases
The role of heme oxygenase-1 in systemic-onset juvenile idiopathic arthritis.
Rhinitis
Ozone-Induced Type 2 Immunity in Nasal Airways. Development and Lymphoid Cell Dependence in Mice.
Rhinitis, Allergic
Heme Oxygenase (HO)-1 Is Upregulated in the Nasal Mucosa With Allergic Rhinitis.
Rhinitis, Allergic
[Anti-allergic effects of xuebijing and potential role of heme oxygenase-1 against ovalbumin-induced murine allergic rhinitis model].
Rhinitis, Allergic
[Expression of heme oxygenase-1 in nasal mucosa of allergic rhinitis guinea pig]
Rickettsia Infections
Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.
Rocky Mountain Spotted Fever
Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression.
Rocky Mountain Spotted Fever
Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
Salmonella Infections
Cytoprotective function of heme oxygenase 1 induced by a nitrated cyclic nucleotide formed during murine salmonellosis.
Sarcoma
Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor.
Sarcoma, Kaposi
Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor.
Sarcoma, Kaposi
Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms.
Sarcoma, Kaposi
The Galpha12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis.
Scleroderma, Localized
UVA irradiation induced heme oxygenase-1: a novel phototherapy for morphea.
Scleroderma, Systemic
Heme oxygenase-1 promoter polymorphisms do not influence susceptibility to systemic sclerosis and its clinical phenotypes.
Scleroderma, Systemic
Low heme oxygenase-1 levels in patients with systemic sclerosis are associated with an altered Toll-like receptor response: another role for CXCL4?
Seizures
Antioxidant roles of heme oxygenase, carbon monoxide, and bilirubin in cerebral circulation during seizures.
Seizures
Cerebrovasodilatory contribution of endogenous carbon monoxide during seizures in newborn pigs.
Seizures
Chronic activation of anti-oxidant pathways and iron accumulation in epileptogenic malformations.
Seizures
Effects of hypoxia preconditioning on expression of metallothionein-1,2 and heme oxygenase-1 before and after kainic acid-induced seizures.
Seizures
Effects of midazolam and phenobarbital on brain oxidative reactions induced by pentylenetetrazole in a convulsion model.
Seizures
Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures.
Seizures
Epileptic seizures cause extended postictal cerebral vascular dysfunction that is prevented by HO-1 overexpression.
Seizures
Inhibition of aconitase in astrocytes increases the sensitivity to chemical convulsants.
Seizures
Soman-induced seizures: limbic activity, oxidative stress and neuroprotective proteins.
Seizures
[Febrile seizure, but not hyperthermia alone, induces the expression of heme oxygenase-1 in rat cortex.]
Seizures, Febrile
Interaction between endogenous nitric oxide and carbon monoxide in the pathogenesis of recurrent febrile seizures.
Seizures, Febrile
[Febrile seizure, but not hyperthermia alone, induces the expression of heme oxygenase-1 in rat cortex.]
Sepsis
3,4,5-Trihydroxycinnamic acid inhibits lipopolysaccharide (LPS)-induced inflammation by Nrf2 activation in vitro and improves survival of mice in LPS-induced endotoxemia model in vivo.
Sepsis
?(1)-Adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice.
Sepsis
A limited series of synthetic tetrahydroisoquinoline alkaloids reduce inflammatory gene iNOS via inhibition of p-STAT-1 and suppress HMGB1 secretion in LPS-treated mice lung tissue.
Sepsis
A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals.
Sepsis
Activation of Mitochondrial Biogenesis by HO-1-mediated Nrf2 Induction Rescues Mice from Lethal S. Aureus Sepsis.
Sepsis
Beneficial effects of the heme oxygenase-1/carbon monoxide system in patients with severe sepsis/septic shock.
Sepsis
Candida albicans heme oxygenase and its product CO contribute to pathogenesis of candidemia and alter systemic chemokine and cytokine expression.
Sepsis
Differential induction of brain heme oxygenase-1 and heat shock protein 70 mRNA in sepsis.
Sepsis
Early expression of heme oxygenase-1 in leukocytes correlates negatively with oxidative stress and predicts hepatic and renal dysfunction at late stage of sepsis.
Sepsis
Enhanced induction of heme oxygenase-1 suppresses thrombus formation and affects the protein C system in sepsis.
Sepsis
Ethanol Extract of Prunella vulgaris var. lilacina Inhibits HMGB1 Release by Induction of Heme Oxygenase-1 in LPS-activated RAW 264.7 Cells and CLP-induced Septic Mice.
Sepsis
Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis.
Sepsis
Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?
Sepsis
Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.
Sepsis
Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression.
Sepsis
Heme oxygenase-1 deficiency promotes severity of sepsis in a non-surgical preterm mouse model.
Sepsis
HEME OXYGENASE-1 SUPPRESSES THE INFILTRATION OF NEUTROPHILS IN RAT LIVER DURING SEPSIS THROUGH INACTIVATION OF P38 MAPK.
Sepsis
Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice.
Sepsis
Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis.
Sepsis
Hepatocyte growth factor prevents multiple organ injuries in endotoxemic mice through a heme oxygenase-1-dependent mechanism.
Sepsis
Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.
Sepsis
Hydrogen Gas Alleviates the Intestinal Injury Caused by Severe Sepsis in Mice by Increasing the Expression of Heme Oxygenase-1.
Sepsis
Induction of Heme OXYGENASE-1 Attenuates the Severity of Sepsis in A Non-Surgical Preterm Mouse Model.
Sepsis
Ketamine reduces LPS-induced HMGB1 via activation of the Nrf2/HO-1 pathway and NF-?B suppression.
Sepsis
Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils.
Sepsis
Nitric oxide synthase is downregulated, while haem oxygenase is increased, in patients with septic shock.
Sepsis
Phosphatidylinositol 3-kinase-mediated HO-1/CO represses Fis1 levels and alleviates lipopolysaccharide-induced oxidative injury in alveolar macrophages.
Sepsis
Protective effect of acacetin on sepsis-induced acute lung injury via its anti-inflammatory and antioxidative activity.
Sepsis
Protective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice.
Sepsis
Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-?B/HIF-1? pathway by binding to HMOX1 in rats with sepsis.
Sepsis
Protective role of heme oxygenase-1 in the intestinal tissue injury in an experimental model of sepsis.
Sepsis
Protective role of heme oxygenases against endotoxin-induced diaphragmatic dysfunction in rats.
Sepsis
Short (GT)n microsatellite repeats in the heme oxygenase-1 gene promoter are associated with antioxidant and anti-inflammatory status in mexican pediatric patients with sepsis.
Sepsis
Stimulation of Alpha7 Nicotinic Acetylcholine Receptor by Nicotine Attenuates Inflammatory Response in Macrophages and Improves Survival in Experimental Model of Sepsis Through Heme Oxygenase-1 Induction.
Sepsis
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1.
Sepsis
The Effects of Arginine and Selective Inducible Nitric Oxide Synthase Inhibitor on Pathophysiology of Sepsis in a CLP Model.
Sepsis
Transient receptor potential melastatin 2-mediated heme oxygenase-1 has a role for bacterial clearance by regulating autophagy in peritoneal macrophages during polymicrobial sepsis.
Sepsis
[Effect of unfractionated heparin on the expression of heme oxygenase-1 in intestinal mucosa of mice with sepsis].
Sepsis
[Hydrogen plays a protective role in intestinal injury of mice with severe sepsis by regulating the release of heme oxygenase-1 and high mobility group protein B1].
Severe Combined Immunodeficiency
HO-1 induction improves the type-1 cardiorenal syndrome in mice with impaired angiotensin II-induced lymphocyte activation.
Shock, Septic
Beneficial effects of the heme oxygenase-1/carbon monoxide system in patients with severe sepsis/septic shock.
Shock, Septic
Electroacupuncture Ameliorates Acute Renal Injury in Lipopolysaccharide-Stimulated Rabbits via Induction of HO-1 through the PI3K/Akt/Nrf2 Pathways.
Shock, Septic
Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress.
Shock, Septic
Nitric oxide synthase is downregulated, while haem oxygenase is increased, in patients with septic shock.
Sialadenitis
Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.
Siderosis
Parkinsonian features in aging GFAP.HMOX1 transgenic mice overexpressing human HO-1 in the astroglial compartment.
Silicosis
0397?Serum heme oxygenase-1 level in silicosis patients and stone mortar and pestle production workers.
Silicosis
Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury.
Silicosis
Serum heme oxygenase-1 as a marker of lung function decline in patients with chronic silicosis.
Sleep Apnea, Obstructive
Activation of heme oxygenase and suppression of cGMP are associated with impaired endothelial function in obstructive sleep apnea with hypertension.
Sleep Apnea, Obstructive
Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Sleep Apnea, Obstructive
Impact of Bariatric Surgery on Heme Oxygenase-1, Inflammation, and Insulin Resistance in Morbid Obesity with Obstructive Sleep Apnea.
Sleep Apnea, Obstructive
Increase in bilirubin levels of patients with obstructive sleep apnea in the morning--a possible explanation of induced heme oxygenase-1.
Sleep Deprivation
Phagocyte migration and cellular stress induced in liver, lung, and intestine during sleep loss and sleep recovery.
Spermatic Cord Torsion
The protective role of heme oxygenase-1 induction on testicular tissues after testicular torsion and detorsion.
Spinal Cord Injuries
A new antioxidant compound H-290/51 attenuates upregulation of constitutive isoform of heme oxygenase (HO-2) following trauma to the rat spinal cord.
Spinal Cord Injuries
Activation of heme oxygenase recovers motor function after spinal cord injury in rats.
Spinal Cord Injuries
Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation.
Spinal Cord Injuries
Co-induction of HSP70 and heme oxygenase-1 in macrophages and glia after spinal cord contusion in the rat.
Spinal Cord Injuries
Effect of canine mesenchymal stromal cells overexpressing heme oxygenase-1 in spinal cord injury.
Spinal Cord Injuries
Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival.
Spinal Cord Injuries
Heme oxygenase-1 expression after spinal cord injury: the induction in activated neutrophils.
Spinal Cord Injuries
Heme oxygenase-1 inhibits neuronal apoptosis in spinal cord injury through down-regulation of Cdc42-MLK3-MKK7-JNK3 axis.
Spinal Cord Injuries
Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury.
Spinal Cord Injuries
Lithium ameliorates rat spinal cord injury by suppressing glycogen synthase kinase-3? and activating heme oxygenase-1.
Spinal Cord Injuries
MEK1/2 Inhibition Synergistically Enhances the Preventive Effects of Normobaric Oxygen on Spinal Cord Injury in Decompression Sickness Rats.
Spinal Cord Injuries
Mitigation of Microglia-mediated Acute Neuroinflammation and Tissue Damage by Heme Oxygenase 1 in a Rat Spinal Cord Injury Model.
Spinal Cord Injuries
Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1.
Spinal Cord Injuries
Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms?
Spondylitis, Ankylosing
Serum Heme Oxygenase-1 and BMP-7 Are Potential Biomarkers for Bone Metabolism in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis.
Spotted Fever Group Rickettsiosis
Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.
Squamous Cell Carcinoma of Head and Neck
Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Chrysosplenol D Triggers Apoptosis through Heme Oxygenase-1 and Mitogen-Activated Protein Kinase Signaling in Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis.
Squamous Cell Carcinoma of Head and Neck
Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients.
Squamous Cell Carcinoma of Head and Neck
Nuclear localization of glutamate-cysteine ligase is associated with proliferation in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Polymorphism in heme oxygenase-1 (HO-1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers.
Squamous Cell Carcinoma of Head and Neck
Protease-activated receptor 2 modulates proliferation and invasion of oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
The Usage of Curcumin as Chemopreventive Agent for Oral Squamous Cell Carcinoma: An Experimental Study on Sprague-Dawley Rat.
Squamous Cell Carcinoma of Head and Neck
Upregulation of heme oxygenase-1 expression in areca-quid-chewing-associated oral squamous cell carcinoma.
Starvation
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Starvation
Sulforaphane ameliorates serum starvation-induced muscle atrophy via activation of the Nrf2 pathway in cultured C2C12 cells.
Still's Disease, Adult-Onset
Beneficial use of serum ferritin and heme oxygenase-1 as biomarkers in adult-onset Still's disease: A multicenter retrospective study.
Stomach Neoplasms
Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis.
Stomach Neoplasms
Association between GT-repeat polymorphism at heme oxygenase-1 gene promoter and gastric cancer and metastasis.
Stomach Neoplasms
Helicobacter pylori infection promotes autophagy through Nrf2-mediated heme oxygenase upregulation in human gastric cancer cells.
Stomach Neoplasms
Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters.
Stomach Neoplasms
Low heme oxygenase-1 expression promotes gastric cancer cell apoptosis, inhibits proliferation and invasion, and correlates with increased overall survival in gastric cancer patients.
Stomach Neoplasms
Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells.
Stomach Neoplasms
ZnPPIX inhibits peritoneal metastasis of gastric cancer via its antiangiogenic activity.
Stomach Ulcer
Expression and immunolocalization of heat shock proteins in the healing of gastric ulcers in rats.
Stomach Ulcer
Heme Oxygenase-1 Is Protective Against Non-Steroidal Anti-Inflammatory Drug-Induced Gastric Ulcers.
Stroke
Association of heme oxygenase-1 gene rs2071746 polymorphism with vascular outcomes in patients with atherosclerotic stroke.
Stroke
Combinational therapy of ischemic brain stroke by delivery of heme oxygenase-1 gene and dexamethasone.
Stroke
Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule.
Stroke
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states.
Stroke
Quantitative imaging mass spectroscopy reveals roles of heme oxygenase-2 for protecting against transhemispheric diaschisis in the brain ischemia.
Stroke
Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1.
Stroke
Stroke outcomes in mice lacking the genes for neuronal heme oxygenase-2 and nitric oxide synthase.
Stroke
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke.
Stroke
Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury.
Subacute Sclerosing Panencephalitis
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Subarachnoid Hemorrhage
Beneficial Properties of Argon After Experimental Subarachnoid Hemorrhage: Early Treatment Reduces Mortality and Influences Hippocampal Protein Expression.
Subarachnoid Hemorrhage
CGS 26303 Upregulates mRNA Expression of Heme Oxygenase-1 in Brain Tissue of Rats Subjected to Experimental Subarachnoid Hemorrhage.
Subarachnoid Hemorrhage
Effect of vasospasm on heme oxygenases in a rat model of subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Heme oxygenase-1 and ferritin are increased in cerebral arteries after subarachnoid hemorrhage in monkeys.
Subarachnoid Hemorrhage
Intracranial heme metabolism and cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1.
Subarachnoid Hemorrhage
miR-24 targets HMOX1 to regulate inflammation and neurofunction in rats with cerebral vasospasm after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Prognostic value of intrathecal heme oxygenase-1 concentration in patients with Fisher Grade III aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm.
Subarachnoid Hemorrhage
Subarachnoid Hemorrhage Increases Level of Heme Oxygenase-1 and Biliverdin Reductase in the Choroid Plexus.
Subarachnoid Hemorrhage
Synergistic induction of heme oxygenase-1 by nicaraven after subarachnoid hemorrhage to prevent delayed cerebral vasospasm.
Subarachnoid Hemorrhage
The role of TLR4 and HO-1 in neuroinflammation after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Zinc protoporphyrin aggravates cerebral ischemic injury following experimental subarachnoid hemorrhage.
Supranuclear Palsy, Progressive
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Supranuclear Palsy, Progressive
Redox metals and oxidative abnormalities in human prion diseases.
Tachycardia
Hemin blunts the depressant effect of chronic nicotine on reflex tachycardia via activation of central NOS/PI3K pathway in female rats.
Takotsubo Cardiomyopathy
Upregulation of Heme Oxygenase-1 in an Animal Model of Takotsubo Cardiomyopathy.
Tauopathies
Overexpression of heme oxygenase 1 causes cognitive decline and affects pathways for tauopathy in mice.
Teratozoospermia
Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats.
Tetanus
On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus.
Thiamine Deficiency
Thiamine Deficiency Modulates p38MAPK and Heme Oxygenase-1 in Mouse Brain: Association with Early Tissue and Behavioral Changes.
Thromboangiitis Obliterans
The Status of Nitric Oxide and its Backup, Heme Oxygenase 1, in Thromboangiitis Obliterans.
Thrombophilia
Bariatric patients have plasmatic hypercoagulability and systemic upregulation of heme oxygenase activity.
Thrombophilia
Heme oxygenase derived carbon monoxide and iron mediated plasmatic hypercoagulability in a patient with calcific mitral valve disease.
Thrombophilia
Iron and carbon monoxide enhance coagulation and attenuate fibrinolysis by different mechanisms.
Thrombosis
Activated protein C accelerates venous thrombus resolution through heme oxygenase-1 induction.
Thrombosis
Bilirubin Levels and Thrombus Burden in Patients With ST-Segment Elevation Myocardial Infarction.
Thrombosis
Carbon monoxide releasing molecule-2 increases the velocity of thrombus growth and strength in human plasma.
Thrombosis
Carbon monoxide-induced early thrombolysis contributes to heme oxygenase-1-mediated inhibition of neointimal growth after vascular injury in hypercholesterolemic mice.
Thrombosis
Enhanced induction of heme oxygenase-1 suppresses thrombus formation and affects the protein C system in sepsis.
Thrombosis
Gain in translation: heme oxygenase-1 induced by activated protein C promotes thrombus resolution.
Thrombosis
Genetic variation in heme oxygenase 1 (HMOX1) and the risk of recurrent venous thromboembolism.
Thrombosis
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.
Thrombosis
Increased risk of venous thromboembolism is associated with genetic variation in heme oxygenase-1 in Blacks.
Thrombosis
Induction of heme oxygenase-1 expression inhibits platelet-dependent thrombosis.
Thrombosis
LOCAL PRECONDITIONING BY THERMAL STRESS ACCELERATES MICROVASCULAR THROMBUS FORMATION.
Thrombosis
Paradoxical protection from atherosclerosis and thrombosis in a mouse model of sickle cell disease.
Thrombosis
The expression of myeloperoxidase in thrombi is associated with reduced heme oxygenase-1 induction and worse left ventricular remodeling in patients with acute ST-elevation myocardial infarction.
Thrombosis
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo.
Thrombotic Microangiopathies
Circulating Heme Oxygenase-1 and Complement Activation in Transplant-Associated Thrombotic Microangiopathy.
Thymoma
Dimerumic Acid and Deferricoprogen Activate Ak Mouse Strain Thymoma/Heme Oxygenase-1 Pathways and Prevent Apoptotic Cell Death in 6-Hydroxydopamine-Induced SH-SY5Y Cells.
Thyroid Cancer, Papillary
Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells.
Thyroid Neoplasms
Heme Oxygenase-1 Inhibitors Induce Cell Cycle Arrest and Suppress Tumor Growth in Thyroid Cancer Cells.
Thyroid Neoplasms
Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells.
Tongue Neoplasms
Preventive Effect of Lactobacillus fermentum CQPC08 on 4-Nitroquineline-1-Oxide Induced Tongue Cancer in C57BL/6 Mice.
Toxoplasmosis
Heme oxygenase-1 activity is involved in the control of Toxoplasma gondii infection in the lung of BALB/c and C57BL/6 and in the small intestine of C57BL/6 mice.
Tricuspid Valve Insufficiency
Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.
Tuberculosis
A Dynamic Substrate is Required for MhuD-Catalyzed Degradation of Heme to Mycobilin.
Tuberculosis
Association of heme oxygenase-1 single nucleotide polymorphisms with susceptibility to tuberculosis in Chinese Han population.
Tuberculosis
Autoantibody-Mediated Erythrophagocytosis Increases Tuberculosis Susceptibility in HIV Patients.
Tuberculosis
cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis.
Tuberculosis
Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide.
Tuberculosis
Heme oxygenase limits Mycobacterium marinum infection-induced detrimental ferrostatin-sensitive cell death in zebrafish.
Tuberculosis
Heme Oxygenase-1 as a Pharmacological Target for Host-Directed Therapy to Limit Tuberculosis Associated Immunopathology.
Tuberculosis
Heme oxygenase-1 inhibition promotes IFN?- and NOS2-mediated control of Mycobacterium tuberculosis infection.
Tuberculosis
Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection.
Tuberculosis
Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis.
Tuberculosis
MhuD from Mycobacterium tuberculosis: Probing a Dual Role in Heme Storage and Degradation.
Tuberculosis
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Tuberculosis
Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes.
Tuberculosis
Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes.
Tuberculosis
Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease.
Tuberculosis, Pulmonary
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Uremia
Uremia induces proximal tubular cytoresistance and heme oxygenase-1 expression in the absence of acute kidney injury.
Ureteral Obstruction
Heme Induces IL-1? Secretion Through Activating NLRP3 in Kidney Inflammation.
Ureteral Obstruction
Heme oxygenase-1 protects rat kidney from ureteral obstruction via an antiapoptotic pathway.
Ureteral Obstruction
Intermedin attenuates renal fibrosis by induction of heme oxygenase-1 in rats with unilateral ureteral obstruction.
Urinary Bladder Neck Obstruction
Upregulation of heme oxygenase and collagen type III in the rat bladder after partial bladder outlet obstruction.
Urinary Bladder Neoplasms
Clinical significance of heme oxygenase-1 expression in non-muscle-invasive bladder cancer.
Urinary Bladder Neoplasms
Curcumin-induced heme oxygenase-1 expression plays a negative role for its anti-cancer effect in bladder cancers.
Urinary Bladder Neoplasms
Exploring the FGFR3-related oncogenic mechanism in bladder cancer using bioinformatics strategy.
Urinary Bladder Neoplasms
Expression of ferrochelatase has a strong correlation in protoporphyrin IX accumulation with photodynamic detection of bladder cancer.
Urinary Bladder Neoplasms
Heme oxygenase-1 expression is associated with tumor aggressiveness and outcomes in patients with bladder cancer: a correlation with smoking intensity.
Urinary Bladder Neoplasms
HMOX1 is an important prognostic indicator of nonmuscle invasive bladder cancer recurrence and progression.
Urinary Bladder Neoplasms
JUND-dependent up-regulation of HMOX1 is associated with cisplatin resistance in muscle-invasive bladder cancer.
Urinary Bladder Neoplasms
Pathological roles of c-Met in bladder cancer: Association with cyclooxygenase-2, heme oxygenase-1, vascular endothelial growth factor-A and programmed death ligand 1.
Urinary Bladder Neoplasms
Pathological significance and prognostic implications of heme oxygenase 1 expression in non-muscle-invasive bladder cancer: Correlation with cell proliferation, angiogenesis, lymphangiogenesis and expression of VEGFs and COX-2.
Urinary Bladder Neoplasms
Prognostic significance of heme oxygenase-1, S100 calcium-binding protein A4, and syndecan-1 expression in primary non-muscle-invasive bladder cancer.
Urinary Tract Infections
miR-204/miR-211 downregulation contributes to Candidemia-induced kidney injuries via derepression of Hmx1 expression.
Urologic Diseases
Protective effects of heme oxygenase-1 against cyclophosphamide-induced haemorrhagic cystitis in rats.
Uterine Cervical Neoplasms
Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines. A possible strategy for the maintenance of intracellular heme level.
Uterine Cervical Neoplasms
Osthole promotes the suppressive effects of cisplatin on NRF2 expression to prevent drug-resistant cervical cancer progression.
Uterine Cervical Neoplasms
Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors.
Uveitis
Hyperglycemia in streptozotocin-induced diabetes leads to persistent inflammation and tissue damage following uveitis due to reduced levels of ciliary body heme oxygenase-1.
Uveitis, Posterior
Effects of heme oxygenase-1 inducer and inhibitor on experimental autoimmune uveoretinitis.
Varicocele
Heme oxygenase enzyme activity in seminal plasma of oligoasthenoteratozoospermic males with varicocele.
Vascular Calcification
Changes of heme oxygenase-carbon monoxide system in vascular calcification in rats.
Vascular Calcification
Up-regulation of heme oxygenase-1 by celastrol alleviates oxidative stress and vascular calcification in chronic kidney disease.
Vascular Diseases
Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling.
Vascular Diseases
Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption.
Vascular Diseases
Heme oxygenase-1 in growth control and its clinical application to vascular disease.
Vascular Diseases
Heme oxygenase-1 inhibition prevents intimal hyperplasia enhancing nitric oxide-dependent apoptosis of vascular smooth muscle cells.
Vascular Diseases
Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress-A New Insight into the Pathophysiology of Vascular Diseases.
Vascular Diseases
Inhibition of plasminogen activator inhibitor-1 expression in vascular smooth muscle cells by protoporphyrins through a heme oxygenase-independent mechanism.
Vascular Diseases
Niacin inhibits vascular inflammation via the induction of heme oxygenase-1.
Vascular Diseases
The effect of a promoter polymorphism in the heme oxygenase-1 gene on the risk of ischaemic cerebrovascular events: the influence of other vascular risk factors.
Vascular Diseases
Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome.
Vascular Diseases
YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.
Vascular Ring
[Administration of hydrogen sulfide intraperitoneally reverses the hyporesponsiveness of rat pulmonary artery induced by lipopolysaccharide and its relationship with carbon monoxide.]
Vascular System Injuries
Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation.
Vascular System Injuries
Anti-oxidant effect of heme oxygenase-1 on cigarette smoke-induced vascular injury.
Vascular System Injuries
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide.
Vascular System Injuries
Ethyl Pyruvate Reduces Acute Lung Injury Via Regulation of iNOS and HO-1 Expression in Endotoxemic Rats.
Vascular System Injuries
Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca(2+) channels.
Vascular System Injuries
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.
Vascular System Injuries
HO-1 and CO Decrease Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cell Migration Via Inhibition of Nox1.
Vascular System Injuries
Induction of heme oxygenase-1 by whisky congeners in human endothelial cells.
Vascular System Injuries
Isoflurane post-treatment improves pulmonary vascular permeability via upregulation of heme oxygenase-1.
Vascular System Injuries
Local administration of carbon monoxide inhibits neointima formation in balloon injured rat carotid arteries.
Vascular System Injuries
Myeloperoxidase oxidized LDL interferes with endothelial cell motility through miR-22 and heme oxygenase 1 induction: possible involvement in reendothelialization of vascular injuries.
Vascular System Injuries
Redox mechanisms of the beneficial effects of heme oxygenase in hypertension.
Vascular System Injuries
Role of hemin in the modulation of H2O2-mediated endothelial cell injury.
Vascular System Injuries
The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.
Vasospasm, Intracranial
Heme oxygenase-1 gene induction as an intrinsic regulation against delayed cerebral vasospasm in rats.
Vasospasm, Intracranial
Intracranial heme metabolism and cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Vasospasm, Intracranial
miR-24 targets HMOX1 to regulate inflammation and neurofunction in rats with cerebral vasospasm after subarachnoid hemorrhage.
Vasospasm, Intracranial
Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm.
Vasospasm, Intracranial
Synergistic induction of heme oxygenase-1 by nicaraven after subarachnoid hemorrhage to prevent delayed cerebral vasospasm.
Vasospasm, Intracranial
Treatment of experimental cerebral vasospasm by protein transduction of heme oxygenase 1 (HO-1) conjugated to a residue of 11 arginines.
Venous Thromboembolism
Genetic variation in heme oxygenase 1 (HMOX1) and the risk of recurrent venous thromboembolism.
Venous Thromboembolism
Increased risk of venous thromboembolism is associated with genetic variation in heme oxygenase-1 in Blacks.
Venous Thrombosis
Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis.
Ventilator-Induced Lung Injury
Heme oxygenase-1 system, inflammation and ventilator-induced lung injury.
Ventilator-Induced Lung Injury
Long-term administration of simvastatin reduces ventilator-induced lung injury and upregulates heme oxygenase 1 expression in a rat model.
Ventilator-Induced Lung Injury
[A study of the role of heme oxygenase-1 expression in ventilator induced lung injury and its mechanism in rats]
Ventricular Fibrillation
Heme oxygenase and cardiac function in ischemic/reperfused rat hearts.
Ventricular Fibrillation
Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium.
Ventricular Fibrillation
Motor Cortex and Hippocampus Display Decreased Heme Oxygenase Activity 2 Weeks After Ventricular Fibrillation Cardiac Arrest in Rats.
Ventricular Fibrillation
Reduction of reperfusion-induced ventricular fibrillation and infarct size via heme oxygenase-1 overexpression in isolated mouse hearts*
Ventricular Fibrillation
Regulation of ventricular fibrillation by heme oxygenase in ischemic/reperfused hearts.
Ventricular Fibrillation
The heme oxygenase inducer hemin protects against cardiac dysfunction and ventricular fibrillation in ischaemic/reperfused rat hearts: role of connexin 43.
Ventricular Fibrillation
The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts.
Viremia
Heme Oxygenase-1 inhibits spring viremia of carp virus replication through carbon monoxide mediated cyclic GMP/Protein kinase G signaling pathway.
Virus Diseases
Chinese herbal medicine compound Yi-Zhi-Hao pellet inhibits replication of influenza virus infection through activation of heme oxygenase-1.
Virus Diseases
Down-regulation of cellular protein heme oxygenase 1 inhibits proliferation of classical swine fever virus in PK-15 cells.
Virus Diseases
Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein.
Virus Diseases
Heme oxygenase-1 acts as an antiviral factor for porcine reproductive and respiratory syndrome virus infection and over-expression inhibits virus replication in vitro.
Virus Diseases
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.
Virus Diseases
Increased carbon monoxide in exhaled air of subjects with upper respiratory tract infections.
Virus Diseases
Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
Virus Diseases
The Activity of SV40 Promoter Can Be Inhibited by Overexpression of Heme Oxygenase-1 in Tumor Cells.
Vitamin A Deficiency
Vitamin A deficiency modulates iron metabolism via ineffective erythropoiesis.
Vitamin B 6 Deficiency
Multiple roles of haem in cystathionine ?-synthase activity: implications for hemin and other therapies of acute hepatic porphyria.
Vitamin E Deficiency
Effects of vitamin E deficiency and glutathione depletion on stress protein heme oxygenase 1 mRNA expression in rat liver and kidney.
Vitiligo
Heme oxygenase-1 expression protects melanocytes from stress-induced cell death: implications for vitiligo.
Wilms Tumor
Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells.
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
evolution
-
Pseudomonas strains exhibit four possible enzyme compositions: (I) BphO, (II) PigA, (III) BphO and PigA and (IV) two PigAs. In Pseudomonas aeruginosa PAO1, PigA is encoded in a cluster together with proteins involved in iron utilization while BphO is functionally and genetically coupled to the phytochrome BphP
physiological function
physiological function
-
role of PigA in iron acquisition, in strains containing no PigA, this function may be fulfilled by BphO
physiological function
enzyme interacts and acquires heme from cytoplasmic heme transport protein holo-PhuS. In mutant strains, the absence of bilverdin IXbeta and bilverdinIXdelta leads to a decrease in extracellular levels of hemophore HasA
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). O69002_PSEAI
198
0
21954
TrEMBL
other Location (Reliability: 2), other Location (Reliability: 1)
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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
molecular docking of inhibitor (E)-2-(4-isopropylbenzylidene)hydrazinecarboximidamide to HemO on the back site and the heme site
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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
H26A/K34A/K132A
mutant does not interact with holo-PhuS and shows no enzymatic activity
N19K/K34A/F117Y/K132A
change in regioselectivity, product is biliverdin IXalpha
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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
54 - 56
melting temperature, wild-type and mutants H26A/K34A/K132A and N19K/K34A/F117Y/K132A
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mourino, S.; Giardina, B.; Reyes-Caballero, H.; Wilks, A.
Metabolite-driven regulation of heme uptake by the biliverdin IXbeta/delta-selective heme oxygenase (HemO) of Pseudomonas aeruginosa
J. Biol. Chem.
291
20503-20515
2016
Pseudomonas aeruginosa (O69002), Pseudomonas aeruginosa
brenda
Heinzl, G.A.; Huang, W.; Yu, W.; Giardina, B.J.; Zhou, Y.; MacKerell, A.D.; Wilks, A.; Xue, F.
Iminoguanidines as allosteric inhibitors of the iron-regulated heme oxygenase (HemO) of Pseudomonas aeruginosa
J. Med. Chem.
59
6929-6942
2016
Pseudomonas aeruginosa (O69002), Pseudomonas aeruginosa
brenda
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Release 2023.1 (January 2023)
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