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Information on EC 1.14.14.162 - flavanone 2-hydroxylase

for references in articles please use BRENDA:EC1.14.14.162

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IUBMB Comments

A cytochrome P-450 (heme thiolate) plant enzyme that catalyses the 2-hydroxylation of multiple flavanones such as (2S)-naringenin, (2S)-eriodictyol, (2S)-pinocembrin, and (2S)-liquiritigenin. The products are meta-stable and exist in an equilibrium with open forms such as 1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane-1,3-dione.

The enzyme appears in viruses and cellular organisms

Synonyms
cyp93g2, flavanone 2-hydroxylase, (2s)-flavanone 2-hydroxylase, osf2h, os06g01250, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a flavanone + [reduced NADPH-hemoprotein reductase] + O2 = a 2-hydroxyflavanone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -, -
Highest Expressing Human Cell Lines
Cell Line Links Gene Links