We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Information on EC 1.14.14.130 - laurate 7-monooxygenase for references in articles please use BRENDA:EC1.14.14.130
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in the synthesis of sporopollenin - a complex polymer found at the outer layer of spores and pollen. It can also act on decanoate (C10), myristate (C14), and palmitate (C16) with lower activity. The enzyme also produces a small amount of products that are hydroxylated at neighboring positions (C-6, C-8 and C-9).
The enzyme appears in viruses and cellular organisms
Synonyms
CYP703A2, CYP703A3,
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CYP703A2
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2 = 7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dodecanoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating)
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in the synthesis of sporopollenin - a complex polymer found at the outer layer of spores and pollen. It can also act on decanoate (C10), myristate (C14), and palmitate (C16) with lower activity. The enzyme also produces a small amount of products that are hydroxylated at neighboring positions (C-6, C-8 and C-9).
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
lauric acid + [reduced NADPH-hemoprotein reductase] + O2
12-hydroxydodecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
specific substrate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
Q9LNJ4
-
-
-
?
dodecanoate + [reduced NADPH-hemoprotein reductase] + O2
7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
specific substrate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
-
-
brenda
-
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
brenda
developing flower
brenda
-
-
brenda
developinmg anther
brenda
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
malfunction
Arabidopsis CYP703A2 knockout lines show impaired pollen development and a partial male-sterile phenotype through impaired pollen wall development with absence of exine
physiological function
-
the enzyme is essential for development of anther cuticle and pollen exine
physiological function
the enzyme provides building blocks for sporopollenin synthesis in pollen
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
C70A2_ARATH
510
1
57854
Swiss-Prot
C70A3_ORYSJ
525
0
59631
Swiss-Prot
A0A346RPF9_9LILI
524
2
59567
TrEMBL
A0A346RPF0_9LILI
523
2
59360
TrEMBL
A0A346RPF3_9LILI
523
2
59321
TrEMBL
A0A346RPE7_9LILI
523
2
59323
TrEMBL
A0A346RPE6_9LILI
523
2
59447
TrEMBL
A0A346RPF5_9LILI
523
2
59367
TrEMBL
A0A346RPE5_PHODC
527
2
59739
TrEMBL
A0A346RPF7_9LILI
527
2
59739
TrEMBL
A0A346RPF6_9LILI
527
2
59739
TrEMBL
A0A346RPF8_9LILI
524
2
59577
TrEMBL
A0A346RPF4_9LILI
523
2
59387
TrEMBL
A0A346RPE8_9LILI
523
2
59403
TrEMBL
A0A346RPE4_ELAGV
522
2
59562
TrEMBL
A0A346RPE9_PHORE
527
2
59581
TrEMBL
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in Saccharomyces cerevisiae strain WAT1
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CYP703A3 expression is directly regulated by TDR
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Dobritsa, A.A.; Shrestha, J.; Morant, M.; Pinot, F.; Matsuno, M.; Swanson, R.; Moller, B.L.; Preuss, D.
CYP704B1 is a long-chain fatty acid omega-hydroxylase essential for sporopollenin synthesis in pollen of Arabidopsis
Plant Physiol.
151
574-589
2009
Arabidopsis thaliana
brenda
Yang, X.; Wu, D.; Shi, J.; He, Y.; Pinot, F.; Grausem, B.; Yin, C.; Zhu, L.; Chen, M.; Luo, Z.; Liang, W.; Zhang, D.
Rice CYP703A3, a cytochrome P450 hydroxylase, is essential for development of anther cuticle and pollen exine
J. Integr. Plant Biol.
56
979-994
2014
Oryza sativa
brenda
Morant, M.; Jorgensen, K.; Schaller, H.; Pinot, F.; Moller, B.L.; Werck-Reichhart, D.; Bak, S.
CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen
Plant Cell
19
1473-1487
2007
Arabidopsis thaliana, Arabidopsis thaliana (Q9LNJ4)
brenda
Select items on the left to see more content.
html completed
HOME
login
history
all enzymes
BRENDA home
History
1.14.14.130 laurate 7-monooxygenase
more
top
Information
