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Information on EC 1.14.13.38 - anhydrotetracycline 6-monooxygenase

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IUBMB Comments
The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics. It can also catalyse EC 1.14.13.234, 12-dehydrotetracycline 5-monooxygenase.
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The enzyme appears in viruses and cellular organisms
Synonyms
anhydrotetracycline oxygenase, anhydrotetracycline monooxygenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
anhydrotetracycline + NADPH + H+ + O2 = 12-dehydrotetracycline + NADP+ + H2O
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