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D-carnitine + NADH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
D-carnitine + NADPH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
D-carnitine + NADH + H+ + O2

(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
D-carnitine + NADH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
D-carnitine + NADH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
D-carnitine + NADPH + H+ + O2

(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
D-carnitine + NADPH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
D-carnitine + NADPH + H+ + O2
(3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
the enzyme shows higher activity with D-carnitine compared to L-carnitine
-
-
?
L-carnitine + NADH + H+ + O2

(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2

(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
L-carnitine + NADH + H+ + O2

(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2

(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
L-carnitine + NADPH + H+ + O2
(3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
-
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Ditullio, D.; Anderson, D.; Chen, C.S.; Sih, C.J.
L-carnitine via enzyme-catalyzed oxidative kinetic resolution
Bioorg. Med. Chem.
2
415-420
1994
Acinetobacter calcoaceticus, Acinetobacter calcoaceticus ATCC 39648, Acinetobacter calcoaceticus ATCC 39647
brenda
Koeth, R.; Levison, B.; Culley, M.; Buffa, J.; Wang, Z.; Gregory, J.; Org, E.; Wu, Y.; Li, L.; Smith, J.; Tang, W.; Didonato, J.; Lusis, A.; Hazen, S.
gamma-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO
Cell Metab.
20
799-812
2014
Escherichia coli, Escherichia coli DH10B
brenda
Zhu, Y.; Jameson, E.; Crosatti, M.; Schaefer, H.; Rajakumar, K.; Bugg, T.D.; Chen, Y.
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota
Proc. Natl. Acad. Sci. USA
111
4268-4273
2014
Acinetobacter baumannii (D0C9N6 AND D0C9N8), Acinetobacter baumannii, Acinetobacter baumannii ATCC19606 (D0C9N6 AND D0C9N8)
brenda