Information on EC 1.14.13.228 - jasmonic acid 12-hydroxylase

ABM

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(-)-jasmonate + NADPH + H+ + O2 = trans-12-hydroxyjasmonate + NADP+ + H2O

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MetaCyc

tuberonate glucoside biosynthesis

jasmonate,NADPH:oxygen oxidoreductase (12-hydroxylating)

Although believed to occur in plants, the enzyme has so far been characterized only from the rice blast fungus, Magnaporthe oryzae. The fungus strategically deploys the enzyme to hydroxylate and inactivate endogenous jasmonate to evade the jasmonate-based innate immunity in rice plants.

(-)-jasmonate + NADPH + H+ + O2

trans-12-hydroxyjasmonate + NADP+ + H2O

Pyricularia oryzae

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739135

Substrates: -
Products: -

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physiological function

Pyricularia oryzae

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the reaction product 12-hydroxyjasmonate is secreted during host penetration and helps evade the defense response. Loss of Abm in Magnaporthe oryzae leads to accumulation of methyljasmonate, which induces host defense and blocks invasive growth. Exogenously added 12-hydroxyjasmonate markedly attenuates immunity induced by loss of ABM in rice

739135

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