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The enzyme, characterized from the bacterium Streptomyces sp. WA46, participates in a pathway for salicylate degradation. cf. EC 188.8.131.52, salicylate 5-hydroxylase.
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The enzyme appears in viruses and cellular organisms
salicylyl-coa 5-hydroxylase, more
2-hydroxybenzoyl-CoA + NADH + H+ + O2 = gentisyl-CoA + NAD+ + H2O
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