Information on EC 1.14.13.201 - beta-amyrin 28-monooxygenase

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EC Tree 1 Oxidoreductases 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor 1.14.13.201 beta-amyrin 28-monooxygenase

IUBMB Comments

The enzyme, found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago truncatula (barrel medic) (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively. The enzyme from Maesa lanceolata (false assegai) (CYP16A75) does not catalyse the reaction to completion, resulting in accumulation of both intermediates.

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Release 2026.1 (March 2026)