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BRENDA support

Information on EC 1.14.13.180 - aklavinone 12-hydroxylase

for references in articles please use BRENDA:EC1.14.13.180

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IUBMB Comments

The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase.

The enzyme appears in viruses and cellular organisms

Synonyms
aklavinone 12-hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
aklavinone + NADPH + H+ + O2 = epsilon-rhodomycinone + NADP+ + H2O
show the reaction diagram
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