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Information on EC 1.14.13.180 - aklavinone 12-hydroxylase

for references in articles please use BRENDA:EC1.14.13.180
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IUBMB Comments
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
DnrF, RdmE, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
aklavinone + NADPH + H+ + O2 = epsilon-rhodomycinone + NADP+ + H2O
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