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Information on EC 1.14.13.15 - cholestanetriol 26-monooxygenase

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transferred to EC 1.14.15.15
IUBMB Comments

The enzyme requires ferredoxin and ferredoxin reductase. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-en-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25.

Synonyms
cholestanetriol 26-monooxygenase, more

Highest Expressing Human Cell Lines
Cell Line Links Gene Links