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Information on EC - cholestanetriol 26-monooxygenase

for references in articles please use BRENDA:EC1.14.13.15

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transferred to EC
IUBMB Comments

The enzyme requires ferredoxin and ferredoxin reductase. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-en-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25.

cholestanetriol 26-monooxygenase, more

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