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Information on EC 1.14.13.122 - chlorophyllide-a oxygenase and Organism(s) Oryza sativa and UniProt Accession Q8S7E1

for references in articles please use BRENDA:EC1.14.13.122
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IUBMB Comments
Chlorophyll b is required for the assembly of stable light-harvesting complexes (LHCs) in the chloroplast of green algae, cyanobacteria and plants [2,3]. Contains a mononuclear iron centre . The enzyme catalyses two successive hydroxylations at the 7-methyl group of chlorophyllide a. The second step yields the aldehyde hydrate, which loses H2O spontaneously to form chlorophyllide b . Chlorophyll a and protochlorophyllide a are not substrates .
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This record set is specific for:
Oryza sativa
UNIPROT: Q8S7E1
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The taxonomic range for the selected organisms is: Oryza sativa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
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Synonyms
chlorophyllide a oxygenase, chlorophyll a oxygenase, oscao1, zmcao1, atptc52, pchlide a oxygenase, chlorophyllide a oxygenase 1, chlorophyll a oxygenase/chlorophyll b synthase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
chlorophyll a oxygenase
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chlorophyllide a oxygenase
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SYSTEMATIC NAME
IUBMB Comments
chlorophyllide-a:oxygen 7-oxidoreductase
Chlorophyll b is required for the assembly of stable light-harvesting complexes (LHCs) in the chloroplast of green algae, cyanobacteria and plants [2,3]. Contains a mononuclear iron centre [3]. The enzyme catalyses two successive hydroxylations at the 7-methyl group of chlorophyllide a. The second step yields the aldehyde hydrate, which loses H2O spontaneously to form chlorophyllide b [2]. Chlorophyll a and protochlorophyllide a are not substrates [2].
CAS REGISTRY NUMBER
COMMENTARY hide
216503-73-0
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
chlorophyllide a + O2 + NADPH + H+
chlorophyllide b + H2O + NADP+
show the reaction diagram
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?
additional information
?
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isozyme CAO1 is important in chlorophyll b biosynthesis
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?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
chlorophyllide a + O2 + NADPH + H+
chlorophyllide b + H2O + NADP+
show the reaction diagram
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?
additional information
?
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isozyme CAO1 is important in chlorophyll b biosynthesis
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?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADPH
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
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gene CAO1 expression is reduced in the dark, while expression of gene CAO2 is induced
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
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gene CAO1 is induced by light, gene CAO2 is down-regulated after exposure to light
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
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chlorophyll a nd chlorophyll b contents in wild-type and mutants plants
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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low enzyme expression
Manually annotated by BRENDA team
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high enzyme expression
Manually annotated by BRENDA team
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etiolated, high enzyme expression
Manually annotated by BRENDA team
additional information
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination and analysis of wild-type and mutants genes, gene structures, overview
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Morita, R.; Kusaba, M.; Yamaguchi, H.; Amano, E.; Miyao, A.; Hirochika, H.; Nishimura, M.
Characterization of chlorophyllide a oxygenase (CAO) in rice
Breed. Sci.
55
361-364
2005
Oryza sativa
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Manually annotated by BRENDA team
Lee, S.; Kim, J.H.; Yoo, E.S.; Lee, C.H.; Hirochika, H.; An, G.
Differential regulation of chlorophyll a oxygenase genes in rice
Plant Mol. Biol.
57
805-818
2005
Oryza sativa
Manually annotated by BRENDA team