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Information on EC 1.14.12.13 - 2-halobenzoate 1,2-dioxygenase

for references in articles please use BRENDA:EC1.14.12.13
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IUBMB Comments
A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component. The latter contains FAD. The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity. Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference.
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The enzyme appears in viruses and cellular organisms
Synonyms
cbdabc, 2-halobenzoate dioxygenase, 2-chlorobenzoate 1,2-dioxygenase, cbdab, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
a 2-halobenzoate + NADH + H+ + O2 = catechol + a halide anion + NAD+ + CO2
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