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Information on EC 1.14.12.11 - toluene dioxygenase

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IUBMB Comments
A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase, and a ferredoxin. Some other aromatic compounds, including ethylbenzene, 4-xylene and some halogenated toluenes, are converted into the corresponding cis-dihydrodiols.
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The enzyme appears in viruses and cellular organisms
Synonyms
nagac, todc1c2ba, isptol, toluene 2,3-dioxygenase, oxygenasetol, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
toluene + NADH + H+ + O2 = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+
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