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Information on EC 1.14.11.57 - L-proline trans-4-hydroxylase

for references in articles please use BRENDA:EC1.14.11.57

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IUBMB Comments

Requires Fe2+ and ascorbate. The enzyme, isolated from multiple bacterial species, only produces trans-4-hydroxy-L-proline (cf. EC 1.14.11.56, L-proline cis-4-hydroxylase).

The enzyme appears in viruses and cellular organisms
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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