Reference on EC 1.14.11.55 - ectoine hydroxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hoeppner, A.; Widderich, N.; Bremer, E.; Smits, S.
Overexpression, crystallization and preliminary X-ray crystallographic analysis of the ectoine hydroxylase from Sphingopyxis alaskensis
Acta Crystallogr. Sect. F
70
493-496
2014
Sphingopyxis alaskensis (Q1GNW5), Sphingopyxis alaskensis
Prabhu, J.; Schauwecker, F.; Grammel, N.; Keller, U.; Bernhard, M.
Functional expression of the ectoine hydroxylase gene (thpD) from Streptomyces chrysomallus in Halomonas elongata
Appl. Environ. Microbiol.
70
3130-3132
2004
Streptomyces anulatus (Q6QUY7), Streptomyces anulatus
Bursy, J.; Kuhlmann, A.U.; Pittelkow, M.; Hartmann, H.; Jebbar, M.; Pierik, A.J.; Bremer, E.
Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses
Appl. Environ. Microbiol.
74
7286-7296
2008
Streptomyces coelicolor, Streptomyces coelicolor A3(2)
Bursy, J.; Pierik, A.J.; Pica, N.; Bremer, E.
Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase
J. Biol. Chem.
282
31147-31155
2007
Virgibacillus salexigens (Q2TDY4), Virgibacillus salexigens
Hoeppner, A.; Widderich, N.; Lenders, M.; Bremer, E.; Smits, S.H.
Crystal structure of the ectoine hydroxylase, a snapshot of the active site
J. Biol. Chem.
289
29570-29583
2014
Sphingopyxis alaskensis (Q1GNW5), Sphingopyxis alaskensis, Sphingopyxis alaskensis DSM 13593 (Q1GNW5)
Eilert, E.; Kranz, A.; Hollenberg, C.P.; Piontek, M.; Suckow, M.
Synthesis and release of the bacterial compatible solute 5-hydroxyectoine in Hansenula polymorpha
J. Biotechnol.
167
85-93
2013
Halomonas elongata (E1VA04), Halomonas elongata DSM 2581 (E1VA04)
Widderich, N.; Pittelkow, M.; Hoeppner, A.; Mulnaes, D.; Buckel, W.; Gohlke, H.; Smits, S.H.; Bremer, E.
Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase
J. Mol. Biol.
426
586-600
2014
Virgibacillus salexigens (Q2TDY4), Virgibacillus salexigens
Reuter, K.; Pittelkow, M.; Bursy, J.; Heine, A.; Craan, T.; Bremer, E.
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD
PLoS ONE
5
e10647
2010
Virgibacillus salexigens (Q2TDY4), Virgibacillus salexigens
Widderich, N.; Hoeppner, A.; Pittelkow, M.; Heider, J.; Smits, S.H.; Bremer, E.
Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms
PLoS ONE
9
e93809
2014
Pseudomonas stutzeri, Paenibacillus lautus (A0A1R1AUM9), Halomonas elongata (E1VA04), Acidiphilium cryptum (JN019030), Alkalilimnicola ehrlichii (JN019031), Sphingopyxis alaskensis (Q1GNW5), Virgibacillus salexigens (Q2TDY4), Virgibacillus salexigens, Pseudomonas stutzeri A1501, Sphingopyxis alaskensis DSM 13593 (Q1GNW5), Halomonas elongata DSM 2581 (E1VA04)
Yang, J.; Wang, Q.; Xu, S.; Guan, W.; Zhao, B.; Dong, H.; Ju, J.
Crystallization and X-ray diffraction of an ectoine hydroxylase from Bacillus pseudofirmus OF4
Wei Sheng Wu Xue Bao
55
1468-1474
2015
Alkalihalophilus pseudofirmus (D3FWN2), Alkalihalophilus pseudofirmus OF4 (D3FWN2)
Tao, P.; Li, H.; Yu, Y.; Gu, J.; Liu, Y.
Ectoine and 5-hydroxyectoine accumulation in the halophile Virgibacillus halodenitrificans PDB-F2 in response to salt stress
Appl. Microbiol. Biotechnol.
100
6779-6789
2016
Virgibacillus halodenitrificans (A0A1B1SPG3), Virgibacillus halodenitrificans PDB-F2 (A0A1B1SPG3)
Widderich, N.; Czech, L.; Elling, F.J.; Koenneke, M.; Stoeveken, N.; Pittelkow, M.; Riclea, R.; Dickschat, J.S.; Heider, J.; Bremer, E.
Strangers in the archaeal world osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus
Environ. Microbiol.
18
1227-1248
2016
Nitrosopumilus maritimus
Widderich, N.; Pittelkow, M.; Hppner, A.; Mulnaes, D.; Buckel, W.; Gohlke, H.; Smits, S.; Bremer, E.
Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase
J. Mol. Biol.
426
586-600
2014
Virgibacillus salexigens (Q2TDY4), Virgibacillus salexigens
Hara, R.; Nishikawa, T.; Okuhara, T.; Koketsu, K.; Kino, K.
Ectoine hydroxylase displays selective trans-3-hydroxylation activity towards L-proline
Appl. Microbiol. Biotechnol.
103
5689-5698
2019
Halomonas elongata (E1VA04), Halomonas elongata, Streptomyces cattleya (F8JYW1), Streptomyces cattleya, Halomonas elongata DSM 2581 (E1VA04), Streptomyces cattleya NBRC 14057 (F8JYW1)
Czech, L.; Wilcken, S.; Czech, O.; Linne, U.; Brauner, J.; Smits, S.H.J.; Galinski, E.A.; Bremer, E.
Exploiting substrate promiscuity of ectoine hydroxylase for regio- and stereoselective modification of homoectoine
Front. Microbiol.
10
2745
2019
Stutzerimonas stutzeri (A4VFY4), Sphingopyxis alaskensis (Q1GNW5), Sphingopyxis alaskensis, Stutzerimonas stutzeri A1501 (A4VFY4), Sphingopyxis alaskensis DSM 13593 (Q1GNW5)
Chen, W.C.; Hsu, C.C.; Wang, L.F.; Lan, J.C.; Chang, Y.K.; Wei, Y.H.
Exploring useful fermentation strategies for the production of hydroxyectoine with a halophilic strain, Halomonas salina BCRC 17875
J. Biosci. Bioeng.
128
332-336
2019
Halomonas salina, Halomonas salina BCRC 17875
Argandona, M.; Piubeli, F.; Reina-Bueno, M.; Nieto, J.J.; Vargas, C.
New insights into hydroxyectoine synthesis and its transcriptional regulation in the broad-salt growing halophilic bacterium Chromohalobacter salexigens
Microb. Biotechnol.
14
1472-1493
2021
Chromohalobacter salexigens (Q1QT61), Chromohalobacter salexigens (Q1RPP0), Chromohalobacter salexigens, Chromohalobacter salexigens DSM 3043 (Q1QT61)
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