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Information on EC 1.14.11.33 - DNA oxidative demethylase and Organism(s) Escherichia coli and UniProt Accession P05050

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IUBMB Comments
Contains iron; activity is slightly stimulated by ascorbate. Catalyses oxidative demethylation of the DNA base lesions N1-methyladenine, N3-methylcytosine, N1-methylguanine, and N3-methylthymine. It works better on single-stranded DNA (ssDNA) and is capable of repairing damaged bases in RNA.
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This record set is specific for:
Escherichia coli
UNIPROT: P05050
Word Map
The taxonomic range for the selected organisms is: Escherichia coli
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
Synonyms
alkbh3, alkbh2, alkbh8, alkb homolog 1, alkylated dna repair protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1-methyladenine-DNA dioxygenase
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alkylated DNA repair protein
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alpha-ketoglutarate-dependent dioxygenase ABH1
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidative demethylation
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demethylation
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PATHWAY SOURCE
PATHWAYS