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Information on EC 1.13.99.3 - tryptophan 2'-dioxygenase

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IUBMB Comments
A hemoprotein. Acts on a number of indole-3-alkane derivatives, oxidizing the 3-side-chain in the 2'-position. Best substrates were L-tryptophan and 5-hydroxy-L-tryptophan.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
indolyl-3-alkane alpha-hydroxylase, tryptophan side chain oxidase, tryptophan side-chain oxidase, tryptophan side chain oxidase ii, tso i, tso ii, tryptophan side chain oxidase type i, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-tryptophan + O2 = (indol-3-yl)glycolaldehyde + CO2 + NH3
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PATHWAY SOURCE
PATHWAYS
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