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Information on EC 1.13.11.54 - acireductone dioxygenase [iron(II)-requiring]

for references in articles please use BRENDA:EC1.13.11.54

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IUBMB Comments

Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
mtcbp-1, osard1, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, fe-ard, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-(methylsulfanyl)-2-oxobutanoate + formate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links